Works matching IS 15250016 AND DT 2014 AND VI 22

Results: 272

Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2056, doi. 10.1038/mt.2014.174

By:

Ranzani, Marco;
Annunziato, Stefano;
Calabria, Andrea;
Brasca, Stefano;
Benedicenti, Fabrizio;
Gallina, Pierangela;
Naldini, Luigi;
Montini, Eugenio

Publication type:

Article

AAV8-Mediated In Vivo Overexpression of miR-155 Enhances the Protective Capacity of Genetically Attenuated Malarial Parasites.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2130, doi. 10.1038/mt.2014.172

By:

Hentzschel, Franziska;
Hammerschmidt-Kamper, Christiane;
Börner, Kathleen;
Heiss, Kirsten;
Knapp, Bettina;
Sattler, Julia M;
Kaderali, Lars;
Castoldi, Mirco;
Bindman, Julia G;
Malato, Yann;
Willenbring, Holger;
Mueller, Ann-Kristin;
Grimm, Dirk

Publication type:

Article

Normalization and Improvement of CNS Deficits in Mice With Hurler Syndrome After Long-term Peripheral Delivery of BBB-targeted Iduronidase.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2028, doi. 10.1038/mt.2014.152

By:

El-Amouri, Salim S;
Dai, Mei;
Han, Jing-Fen;
Brady, Roscoe O;
Pan, Dao

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2014, v. 22, n. 12, p. 2016, doi. 10.1038/mt.2014.212
Publication type:: Article

Intrathecal Gene Therapy Corrects CNS Pathology in a Feline Model of Mucopolysaccharidosis I.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2018, doi. 10.1038/mt.2014.135

By:

Hinderer, Christian;
Bell, Peter;
Gurda, Brittney L;
Wang, Qiang;
Louboutin, Jean-Pierre;
Zhu, Yanqing;
Bagel, Jessica;
O'Donnell, Patricia;
Sikora, Tracey;
Ruane, Therese;
Wang, Ping;
Haskins, Mark E;
Wilson, James M

Publication type:

Article

Systemic Administration of Platelets Incorporating Inactivated Sendai Virus Eradicates Melanoma in Mice.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2046, doi. 10.1038/mt.2014.128

By:

Nishikawa, Tomoyuki;
Tung, Li Yu;
Kaneda, Yasufumi

Publication type:

Article

Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2038, doi. 10.1038/mt.2014.127

By:

Ishikawa, Kiyotake;
Fish, Kenneth M;
Tilemann, Lisa;
Rapti, Kleopatra;
Aguero, Jaume;
Santos-Gallego, Carlos G;
Lee, Ahyoung;
Karakikes, Ioannis;
Xie, Chaoqin;
Akar, Fadi G;
Shimada, Yuichi J;
Gwathmey, Judith K;
Asokan, Aravind;
McPhee, Scott;
Samulski, Jade;
Samulski, Richard Jude;
Sigg, Daniel C;
Weber, Thomas;
Kranias, Evangelia G;
Hajjar, Roger J

Publication type:

Article

Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2083, doi. 10.1038/mt.2014.137

By:

Schmid, Daniela;
Fay, Francois;
Small, Donna M;
Jaworski, Jakub;
Riley, Joel S;
Tegazzini, Diana;
Fenning, Cathy;
Jones, David S;
Johnston, Patrick G;
Longley, Daniel B;
Scott, Christopher J

Publication type:

Article

Erratum to 'Serum-stabilized Naked Caspase-3 siRNA Protects Autotransplant Kidneys in a Porcine Model'.

Published in:: Molecular Therapy, 2014, v. 22, n. 12, p. 2156, doi. 10.1038/mt.2014.183
Publication type:: Article

A Question of Reproducibility.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2015, doi. 10.1038/mt.2014.211

By:

Frederickson, Robert M;
Brenner, Malcolm K

Publication type:

Article

A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2118, doi. 10.1038/mt.2014.133

By:

Brito, Luis A;
Chan, Michelle;
Shaw, Christine A;
Hekele, Armin;
Carsillo, Thomas;
Schaefer, Mary;
Archer, Jacob;
Seubert, Anja;
Otten, Gillis R;
Beard, Clayton W;
Dey, Antu K;
Lilja, Anders;
Valiante, Nicholas M;
Mason, Peter W;
Mandl, Christian W;
Barnett, Susan W;
Dormitzer, Philip R;
Ulmer, Jeffrey B;
Singh, Manmohan;
O'Hagan, Derek T

Publication type:

Article

Oral Delivery of ACE2/Ang-(1-7) Bioencapsulated in Plant Cells Protects against Experimental Uveitis and Autoimmune Uveoretinitis.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2069, doi. 10.1038/mt.2014.179

By:

Shil, Pollob K;
Kwon, Kwang-Chul;
Zhu, Ping;
Verma, Amrisha;
Daniell, Henry;
Li, Qiuhong

Publication type:

Article

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2093, doi. 10.1038/mt.2014.153

By:

Southwell, Amber L;
Skotte, Niels H;
Kordasiewicz, Holly B;
Østergaard, Michael E;
Watt, Andrew T;
Carroll, Jeffrey B;
Doty, Crystal N;
Villanueva, Erika B;
Petoukhov, Eugenia;
Vaid, Kuljeet;
Xie, Yuanyun;
Freier, Susan M;
Swayze, Eric E;
Seth, Punit P;
Bennett, Clarence Frank;
Hayden, Michael R

Publication type:

Article

Corrigendum to 'CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes'.

Published in:: Molecular Therapy, 2014, v. 22, n. 12, p. 2155, doi. 10.1038/mt.2014.203
Publication type:: Article

Research Highlights.

Published in:: Molecular Therapy, 2014, v. 22, n. 12, p. 2017, doi. 10.1038/mt.2014.213
Publication type:: Article

Co-Expression of Tumor Antigen and Interleukin-2 From an Adenoviral Vector Augments the Efficiency of Therapeutic Tumor Vaccination.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2107, doi. 10.1038/mt.2014.130

By:

Jensen, Benjamin Anderschou Holbech;
Steffensen, Maria Abildgaard;
Nielsen, Karen Nørgaard;
Christensen, Jan Pravsgaard;
Thomsen, Allan Randrup;
Holst, Peter Johannes

Publication type:

Article

Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2142, doi. 10.1038/mt.2014.157

By:

Hodgson, Susanne H;
Choudhary, Prateek;
Elias, Sean C;
Milne, Kathryn H;
Rampling, Thomas W;
Biswas, Sumi;
Poulton, Ian D;
Miura, Kazutoyo;
Douglas, Alexander D;
Alanine, Daniel GW;
Illingworth, Joseph J;
de Cassan, Simone C;
Zhu, Daming;
Nicosia, Alfredo;
Long, Carole A;
Moyle, Sarah;
Berrie, Eleanor;
Lawrie, Alison M;
Wu, Yimin;
Ellis, Ruth D

Publication type:

Article

Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1992, doi. 10.1038/mt.2014.109

By:

Kimani, Domtila;
Jagne, Ya Jankey;
Cox, Momodou;
Kimani, Eva;
Bliss, Carly M;
Gitau, Evelyn;
Ogwang, Caroline;
Afolabi, Muhammed O;
Bowyer, Georgina;
Collins, Katharine A;
Edwards, Nick;
Hodgson, Susanne H;
Duncan, Christopher J A;
Spencer, Alexandra J;
Knight, Miguel G;
Drammeh, Abdoulie;
Anagnostou, Nicholas A;
Berrie, Eleanor;
Moyle, Sarah;
Gilbert, Sarah C

Publication type:

Article

Neovascularization Capacity of Mesenchymal Stromal Cells From Critical Limb Ischemia Patients Is Equivalent to Healthy Controls.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1960, doi. 10.1038/mt.2014.161

By:

Gremmels, Hendrik;
Teraa, Martin;
Quax, Paul HA;
den Ouden, Krista;
Fledderus, Joost O;
Verhaar, Marianne C

Publication type:

Article

CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1949, doi. 10.1038/mt.2014.160

By:

Engeland, Christine E;
Grossardt, Christian;
Veinalde, Rūta;
Bossow, Sascha;
Lutz, Diana;
Kaufmann, Johanna K;
Shevchenko, Ivan;
Umansky, Viktor;
Nettelbeck, Dirk M;
Weichert, Wilko;
Jäger, Dirk;
von Kalle, Christof;
Ungerechts, Guy

Publication type:

Article

Erratum to 'Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy'.

Published in:: Molecular Therapy, 2014, v. 22, n. 11, p. 2013, doi. 10.1038/mt.2014.182
Publication type:: Article

A Chaperone Enhances Blood α-Glucosidase Activity in Pompe Disease Patients Treated With Enzyme Replacement Therapy.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 2004, doi. 10.1038/mt.2014.138

By:

Parenti, Giancarlo;
Fecarotta, Simona;
la Marca, Giancarlo;
Rossi, Barbara;
Ascione, Serena;
Donati, Maria Alice;
Morandi, Lucia Ovidia;
Ravaglia, Sabrina;
Pichiecchio, Anna;
Ombrone, Daniela;
Sacchini, Michele;
Pasanisi, Maria Barbara;
De Filippi, Paola;
Danesino, Cesare;
Della Casa, Roberto;
Romano, Alfonso;
Mollica, Carmine;
Rosa, Margherita;
Agovino, Teresa;
Nusco, Edoardo

Publication type:

Article

A Theranostic 'SMART' Aptamer for Targeted Therapy of Prostate Cancer.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1886, doi. 10.1038/mt.2014.190

By:

de Franciscis, Vittorio

Publication type:

Article

How To Train Your Oncolytic Virus: the Immunological Sequel.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1881, doi. 10.1038/mt.2014.188

By:

Vile, Richard G

Publication type:

Article

Long-Term Skin Regeneration From a Gene-Targeted Human Epidermal Stem Cell Clone.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1878, doi. 10.1038/mt.2014.187

By:

Duarte, Blanca;
Miselli, Francesca;
Murillas, Rodolfo;
Espinosa-Hevia, Luis;
Cigudosa, Juan Cruz;
Recchia, Alessandra;
Del Río, Marcela;
Larcher, Fernando

Publication type:

Article

Corrigendum to 'Proapoptotic Peptide-Mediated Cancer Therapy Targeted to Cell Surface p32'.

Published in:: Molecular Therapy, 2014, v. 22, n. 11, p. 2013, doi. 10.1038/mt.2014.136
Publication type:: Article

Could Exon Skipping Help Dystrophic Boys to Run, Hop, and Jump?

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1884, doi. 10.1038/mt.2014.189

By:

Partridge, Terence

Publication type:

Article

MSCs Isolated From Patients With Ischemic Vascular Disease Have Normal Angiogenic Potential.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1888, doi. 10.1038/mt.2014.191

By:

Sanz-Nogués, Clara;
O'Brien, Timothy

Publication type:

Article

Erratum to 'Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation'.

Published in:: Molecular Therapy, 2014, v. 22, n. 11, p. 2013, doi. 10.1038/mt.2014.158
Publication type:: Article

RNAi-mediated TCR Knockdown Prevents Autoimmunity in Mice Caused by Mixed TCR Dimers Following TCR Gene Transfer.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1983, doi. 10.1038/mt.2014.142

By:

Bunse, Mario;
Bendle, Gavin M;
Linnemann, Carsten;
Bies, Laura;
Schulz, Stephan;
Schumacher, Ton N;
Uckert, Wolfgang

Publication type:

Article

Forelimb Treatment in a Large Cohort of Dystrophic Dogs Supports Delivery of a Recombinant AAV for Exon Skipping in Duchenne Patients.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1923, doi. 10.1038/mt.2014.151

By:

Le Guiner, Caroline;
Montus, Marie;
Servais, Laurent;
Cherel, Yan;
Francois, Virginie;
Thibaud, Jean-Laurent;
Wary, Claire;
Matot, Béatrice;
Larcher, Thibaut;
Guigand, Lydie;
Dutilleul, Maeva;
Domenger, Claire;
Allais, Marine;
Beuvin, Maud;
Moraux, Amélie;
Le Duff, Johanne;
Devaux, Marie;
Jaulin, Nicolas;
Guilbaud, Mickaël;
Latournerie, Virginie

Publication type:

Article

Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1910, doi. 10.1038/mt.2014.117

By:

Dassie, Justin P;
Hernandez, Luiza I;
Thomas, Gregory S;
Long, Matthew E;
Rockey, William M;
Howell, Craig A;
Chen, Yani;
Hernandez, Frank J;
Liu, Xiu Ying;
Wilson, Mary E;
Allen, Lee-Ann;
Vaena, Daniel A;
Meyerholz, David K;
Giangrande, Paloma H

Publication type:

Article

The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1936, doi. 10.1038/mt.2014.134

By:

Alonso-Camino, Vanesa;
Rajani, Karishma;
Kottke, Timothy;
Rommelfanger-Konkol, Diana;
Zaidi, Shane;
Thompson, Jill;
Pulido, Jose;
Ilett, Elizabeth;
Donnelly, Oliver;
Selby, Peter;
Pandha, Hardev;
Melcher, Alan;
Harrington, Kevin;
Diaz, Rosa Maria;
Vile, Richard

Publication type:

Article

Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1900, doi. 10.1038/mt.2014.139

By:

Marsic, Damien;
Govindasamy, Lakshmanan;
Currlin, Seth;
Markusic, David M;
Tseng, Yu-Shan;
Herzog, Roland W;
Agbandje-McKenna, Mavis;
Zolotukhin, Sergei

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2014, v. 22, n. 11, p. 1876, doi. 10.1038/mt.2014.185
Publication type:: Article

Muscle and Heart Function Restoration in a Limb Girdle Muscular Dystrophy 2I (LGMD2I) Mouse Model by Systemic FKRP Gene Delivery.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1890, doi. 10.1038/mt.2014.141

By:

Qiao, Chunping;
Wang, Chi-Hsien;
Zhao, Chunxia;
Lu, Peijuan;
Awano, Hiroyuki;
Xiao, Bin;
Li, Jianbin;
Yuan, Zhenhua;
Dai, Yi;
Martin, Carrie Bette;
Li, Juan;
Lu, Qilong;
Xiao, Xiao

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2014, v. 22, n. 11, p. 1877, doi. 10.1038/mt.2014.186
Publication type:: Article

Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1971, doi. 10.1038/mt.2014.103

By:

Padmashali, Roshan M;
Mistriotis, Panagiotis;
Liang, Mao-shih;
Andreadis, Stelios T

Publication type:

Article

Where Is the Good in Goodbye?

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1873, doi. 10.1038/mt.2014.184

By:

Brenner, Malcolm K

Publication type:

Article

Leap of Faith.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1717, doi. 10.1038/mt.2014.165

By:

Morgan, Rick

Publication type:

Article

Induction of Androgen Formation in the Male by a TAT-VDAC1 Fusion Peptide Blocking 14-3-3ɛ Protein Adaptor and Mitochondrial VDAC1 Interactions.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1779, doi. 10.1038/mt.2014.116

By:

Aghazadeh, Yasaman;
Martinez-Arguelles, Daniel B;
Fan, Jinjiang;
Culty, Martine;
Papadopoulos, Vassilios

Publication type:

Article

Epicardial Placement of Mesenchymal Stromal Cell-sheets for the Treatment of Ischemic Cardiomyopathy; In Vivo Proof-of-concept Study.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1864, doi. 10.1038/mt.2014.110

By:

Tano, Nobuko;
Narita, Takuya;
Kaneko, Masahiro;
Ikebe, Chiho;
Coppen, Steven R;
Campbell, Niall G;
Shiraishi, Manabu;
Shintani, Yasunori;
Suzuki, Ken

Publication type:

Article

MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1829, doi. 10.1038/mt.2014.113

By:

Vinciguerra, Antonio;
Formisano, Luigi;
Cerullo, Pierpaolo;
Guida, Natascia;
Cuomo, Ornella;
Esposito, Alba;
Di Renzo, Gianfranco;
Annunziato, Lucio;
Pignataro, Giuseppe

Publication type:

Article

A Transgenic Probiotic Secreting a Parasite Immunomodulator for Site-Directed Treatment of Gut Inflammation.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1730, doi. 10.1038/mt.2014.125

By:

Whelan, Rose A;
Rausch, Sebastian;
Ebner, Friederike;
Günzel, Dorothee;
Richter, Jan F;
Hering, Nina A;
Schulzke, Jörg-Dieter;
Kühl, Anja A;
Keles, Ahmed;
Janczyk, Pawel;
Nöckler, Karsten;
Wieler, Lothar H;
Hartmann, Susanne

Publication type:

Article

Peptide Targeting of Mitochondria Elicits Testosterone Formation.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1727, doi. 10.1038/mt.2014.171

By:

Campanella, Michelangelo

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2014, v. 22, n. 10, p. 1721, doi. 10.1038/mt.2014.167
Publication type:: Article

Small-Molecule Therapies for Genetic Skin Fragility.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1724, doi. 10.1038/mt.2014.169

By:

Bruckner-Tuderman, Leena

Publication type:

Article

Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1792, doi. 10.1038/mt.2014.99

By:

Hu, Chuhong;
Kasten, Jennifer;
Park, Hana;
Bhargava, Ragini;
Tai, Denise S;
Grody, Wayne W;
Nguyen, Quynh G;
Hauschka, Stephen D;
Cederbaum, Stephen D;
Lipshutz, Gerald S

Publication type:

Article

Serum-stabilized Naked Caspase-3 siRNA Protects Autotransplant Kidneys in a Porcine Model.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1817, doi. 10.1038/mt.2014.111

By:

Yang, Cheng;
Zhao, Tian;
Zhao, Zitong;
Jia, Yichen;
Li, Long;
Zhang, Yufang;
Song, Mangen;
Rong, Ruiming;
Xu, Ming;
Nicholson, Michael L;
Zhu, Tongyu;
Yang, Bin

Publication type:

Article

ESCRT-mediated Uptake and Degradation of Brain-targeted α-synuclein Single Chain Antibody Attenuates Neuronal Degeneration In Vivo.

Published in:

Molecular Therapy, 2014, v. 22, n. 10, p. 1753, doi. 10.1038/mt.2014.129

By:

Spencer, Brian;
Emadi, Sharareh;
Desplats, Paula;
Eleuteri, Simona;
Michael, Sarah;
Kosberg, Kori;
Shen, Jay;
Rockenstein, Edward;
Patrick, Christina;
Adame, Anthony;
Gonzalez, Tania;
Sierks, Michael;
Masliah, Eliezer

Publication type:

Article