Works matching IS 15250016 AND DT 2013 AND VI 21

Results: 293

A Novel Chimeric Adenoassociated Virus 2/Human Bocavirus 1 Parvovirus Vector Efficiently Transduces Human Airway Epithelia.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2181, doi. 10.1038/mt.2013.92

By:

Yan, Ziying;
Keiser, Nicholas W;
Song, Yi;
Deng, Xuefeng;
Cheng, Fang;
Qiu, Jianming;
Engelhardt, John F

Publication type:

Article

Comparison of Fetal Mesencephalic Grafts, AAV-delivered GDNF, and Both Combined in an MPTP-induced Nonhuman Primate Parkinson's Model.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2160, doi. 10.1038/mt.2013.180

By:

Redmond Jr, D Eugene;
McEntire, Caleb R S;
Kingsbery, Joseph P;
Leranth, Csaba;
Elsworth, John D;
Bjugstad, Kimberly B;
Roth, Robert H;
Samulski, Richard J;
Sladek Jr, John R

Publication type:

Article

A Single Intravenous rAAV Injection as Late as P20 Achieves Efficacious and Sustained CNS Gene Therapy in Canavan Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2136, doi. 10.1038/mt.2013.138

By:

Ahmed, Seemin Seher;
Li, Huapeng;
Cao, Chunyan;
Sikoglu, Elif M;
Denninger, Andrew R;
Su, Qin;
Eaton, Samuel;
Liso Navarro, Ana A;
Xie, Jun;
Szucs, Sylvia;
Zhang, Hongwei;
Moore, Constance;
Kirschner, Daniel A;
Seyfried, Thomas N;
Flotte, Terence R;
Matalon, Reuben;
Gao, Guangping

Publication type:

Article

Oversized AAV Transductifon Is Mediated via a DNA-PKcs-independent, Rad51C-dependent Repair Pathway.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2205, doi. 10.1038/mt.2013.184

By:

Hirsch, Matthew L;
Li, Chengwen;
Bellon, Isabella;
Yin, Chaoying;
Chavala, Sai;
Pryadkina, Marina;
Richard, Isabelle;
Samulski, Richard Jude

Publication type:

Article

In this issue.

Published in:: Molecular Therapy, 2013, v. 21, n. 12, p. 2134, doi. 10.1038/mt.2013.253
Publication type:: Article

Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2148, doi. 10.1038/mt.2013.211

By:

Foust, Kevin D;
Salazar, Desirée L;
Likhite, Shibi;
Ferraiuolo, Laura;
Ditsworth, Dara;
Ilieva, Hristelina;
Meyer, Kathrin;
Schmelzer, Leah;
Braun, Lyndsey;
Cleveland, Don W;
Kaspar, Brian K

Publication type:

Article

Proapoptotic Peptide-Mediated Cancer Therapy Targeted to Cell Surface p32.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2195, doi. 10.1038/mt.2013.191

By:

Agemy, Lilach;
Kotamraju, Venkata R;
Friedmann-Morvinski, Dinorah;
Sharma, Shweta;
Sugahara, Kazuki N;
Ruoslahti, Erkki

Publication type:

Article

Arming Cytokine-induced Killer Cells With Chimeric Antigen Receptors: CD28 Outperforms Combined CD28-OX40 'Super-stimulation'.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2268, doi. 10.1038/mt.2013.192

By:

Hombach, Andreas A;
Rappl, Gunter;
Abken, Hinrich

Publication type:

Article

Engraftment of nonintegrating neural stem cells differentially perturbs cortical activity in a dose-dependent manner.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2258, doi. 10.1038/mt.2013.163

By:

Weerakkody, Tanya N;
Patel, Tapan P;
Yue, Cuiyong;
Takano, Hajime;
Anderson, Hayley C;
Meaney, David F;
Coulter, Douglas A;
Wolfe, John H

Publication type:

Article

Functional Neuroprotection and Efficient Regulation of GDNF Using Destabilizing Domains in a Rodent Model of Parkinson's Disease.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2169, doi. 10.1038/mt.2013.169

By:

Quintino, Luis;
Manfré, Giuseppe;
Wettergren, Erika Elgstrand;
Namislo, Angrit;
Isaksson, Christina;
Lundberg, Cecilia

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2013, v. 21, n. 12, p. 2135, doi. 10.1038/mt.2013.254
Publication type:: Article

To Skip or Not to Skip: That Is the Question for Duchenne Muscular Dystrophy.

Published in:: Molecular Therapy, 2013, v. 21, n. 12, p. 2131, doi. 10.1038/mt.2013.252
Publication type:: Article

A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2236, doi. 10.1038/mt.2013.178

By:

Hoehlig, Kai;
Maasch, Christian;
Shushakova, Nelli;
Buchner, Klaus;
Huber-Lang, Markus;
Purschke, Werner G;
Vater, Axel;
Klussmann, Sven

Publication type:

Article

Intracellular Tracking of Single-plasmid DNA Particles After Delivery by Electroporation.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2217, doi. 10.1038/mt.2013.182

By:

Rosazza, Christelle;
Buntz, Annette;
Rieß, Thorsten;
Wöll, Dominik;
Zumbusch, Andreas;
Rols, Marie-Pierre

Publication type:

Article

Silencing PP2A Inhibitor by Lenti-shRNA Interference Ameliorates Neuropathologies and Memory Deficits in tg2576 Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2247, doi. 10.1038/mt.2013.189

By:

Liu, Gong-Ping;
Wei, Wei;
Zhou, Xin;
Shi, Hai-Rong;
Liu, Xing-Hua;
Chai, Gao-Shang;
Yao, Xiu-Qing;
Zhang, Jia-Yu;
Peng, Cai-Xia;
Hu, Juan;
Li, Xia-Chun;
Wang, Qun;
Wang, Jian-Zhi

Publication type:

Article

The Role of Apoptosis in Immune Hyporesponsiveness Following AAV8 Liver Gene Transfer.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2227, doi. 10.1038/mt.2013.94

By:

Faust, Susan M;
Bell, Peter;
Zhu, Yanqing;
Sanmiguel, Julio;
Wilson, James M

Publication type:

Article

N-acetylcysteine Amide Augments the Therapeutic Effect of Neural Stem Cell-Based Antiglioma Oncolytic Virotherapy.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2063, doi. 10.1038/mt.2013.179

By:

Kim, Chung Kwon;
Ahmed, Atique U;
Auffinger, Brenda;
Ulasov, Ilya V;
Tobias, Alex L;
Moon, Kyung-Sub;
Lesniak, Maciej S

Publication type:

Article

Measles Virus Entry Through the Signaling Lymphocyte Activation Molecule Governs Efficacy of Mantle Cell Lymphoma Radiovirotherapy.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2019, doi. 10.1038/mt.2013.171

By:

Miest, Tanner S;
Frenzke, Marie;
Cattaneo, Roberto

Publication type:

Article

CAR T Cells for Acute Myeloid Leukemia: The LeY of the Land.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 1983, doi. 10.1038/mt.2013.234

By:

Brenner, Malcolm K

Publication type:

Article

Antifibrotic Properties of Transarterial Oncolytic VSV Therapy for Hepatocellular Carcinoma in Rats With Thioacetamide-Induced Liver Fibrosis.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2032, doi. 10.1038/mt.2013.181

By:

Altomonte, Jennifer;
Marozin, Sabrina;
De Toni, Enrico N;
Rizzani, Antonia;
Esposito, Irene;
Steiger, Katja;
Feuchtinger, Annette;
Hellerbrand, Claus;
Schmid, Roland M;
Ebert, Oliver

Publication type:

Article

Inactive ERBB Receptors Cooperate With Reactive Oxygen Species To Suppress Cancer Progression.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 1996, doi. 10.1038/mt.2013.196

By:

Hart, Matthew R;
Su, Hsin-Yuan;
Broka, Derrick;
Goverdhan, Aarthi;
Schroeder, Joyce A

Publication type:

Article

Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2087, doi. 10.1038/mt.2013.185

By:

Hegde, Meenakshi;
Corder, Amanda;
Chow, Kevin KH;
Mukherjee, Malini;
Ashoori, Aidin;
Kew, Yvonne;
Zhang, Yi Jonathan;
Baskin, David S;
Merchant, Fatima A;
Brawley, Vita S;
Byrd, Tiara T;
Krebs, Simone;
Wu, Meng Fen;
Liu, Hao;
Heslop, Helen E;
Gottachalk, Stephen;
Yvon, Eric;
Ahmed, Nabil

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2013, v. 21, n. 11, p. 1974, doi. 10.1038/mt.2013.224
Publication type:: Article

Corrigendum: Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients.

Published in:: Molecular Therapy, 2013, v. 21, n. 11, p. 2130, doi. 10.1038/mt.2013.229
Publication type:: Article

Birth of a New Therapeutic Platform: 47 Years of Adeno-associated Virus Biology From Virus Discovery to Licensed Gene Therapy.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 1976, doi. 10.1038/mt.2013.226

By:

Flotte, Terence R

Publication type:

Article

Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2113, doi. 10.1038/mt.2013.151

By:

Gerdemann, Ulrike;
Katari, Usha L;
Papadopoulou, Anastasia;
Keirnan, Jacqueline M;
Craddock, John A;
Liu, Hao;
Martinez, Caridad A;
Kennedy-Nasser, Alana;
Leung, Kathryn S;
Gottschalk, Stephen M;
Krance, Robert A;
Brenner, Malcolm K;
Rooney, Cliona M;
Heslop, Helen E;
Leen, Ann M

Publication type:

Article

Finding Common Ground: A Summary of the IOM's Review of the RAC.

Published in:: Molecular Therapy, 2013, v. 21, n. 11, p. 1971, doi. 10.1038/mt.2013.223
Publication type:: Article

Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2074, doi. 10.1038/mt.2013.195

By:

Whilding, Lynsey M;
Archibald, Kyra M;
Kulbe, Hagen;
Balkwill, Frances R;
Öberg, Daniel;
McNeish, Iain A

Publication type:

Article

Enhanced Oncolytic Virotherapy Through Oxidative Stress Inhibition.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 1981, doi. 10.1038/mt.2013.227

By:

Congdon, Kendra L;
Sampson, John H

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2013, v. 21, n. 11, p. 1975, doi. 10.1038/mt.2013.225
Publication type:: Article

Corrigendum: 'A Comprehensive Review of Retinal Gene Therapy'.

Published in:: Molecular Therapy, 2013, v. 21, n. 11, p. 2130, doi. 10.1038/mt.2013.228
Publication type:: Article

Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2122, doi. 10.1038/mt.2013.154

By:

Ritchie, David S.;
Neeson, Paul J.;
Khot, Amit;
Peinert, Stefan;
Tai, Tsin;
Tainton, Kellie;
Chen, Karen;
Shin, Mandy;
Wall, Dominic M.;
Hönemann, Dirk;
Gambell, Peter;
Westerman, David A.;
Haurat, Javier;
Westwood, Jennifer A.;
Scott, Andrew M.;
Kravets, Lucy;
Dickinson, Michael;
Trapani, Joseph A.;
Smyth, Mark J.;
Darcy, Phillip K.

Publication type:

Article

Triptolide-Mediated Inhibition of Interferon Signaling Enhances Vesicular Stomatitis Virus-Based Oncolysis.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2043, doi. 10.1038/mt.2013.187

By:

Ben Yebdri, Fethia;
Van Grevenynghe, Julien;
Tang, Vera A;
Goulet, Marie-Line;
Wu, Jian Hui;
Stojdl, David F;
Hiscott, John;
Lin, Rongtuan

Publication type:

Article

Donor Bone Marrow-derived Dendritic Cells Prolong Corneal Allograft Survival and Promote an Intragraft Immunoregulatory Milieu.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2102, doi. 10.1038/mt.2013.167

By:

O'Flynn, Lisa;
Treacy, Oliver;
Ryan, Aideen E;
Morcos, Maurice;
Cregg, Marese;
Gerlach, Jared;
Joshi, Lokesh;
Nosov, Mikhail;
Ritter, Thomas

Publication type:

Article

An Infection-enhanced Oncolytic Adenovirus Secreting H. pylori Neutrophil-activating Protein with Therapeutic Effects on Neuroendocrine Tumors.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2008, doi. 10.1038/mt.2013.153

By:

Ramachandran, Mohanraj;
Yu, Di;
Wanders, Alkwin;
Essand, Magnus;
Eriksson, Fredrik

Publication type:

Article

Engineering of Bacteria for the Visualization of Targeted Delivery of a Cytolytic Anticancer Agent.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 1985, doi. 10.1038/mt.2013.183

By:

Jiang, Sheng-Nan;
Park, Seung-Hwan;
Lee, Hee Jung;
Zheng, Jin Hai;
Kim, Hyung-Seok;
Bom, Hee-Seung;
Hong, Yeongjin;
Szardenings, Michael;
Shin, Myung Geun;
Kim, Sun-Chang;
Ntziachristos, Vasilis;
Choy, Hyon E;
Min, Jung-Joon

Publication type:

Article

Vaccinia Virus-mediated Expression of Human Erythropoietin in Tumors Enhances Virotherapy and Alleviates Cancer-related Anemia in Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2054, doi. 10.1038/mt.2013.149

By:

Nguyen, Duong H;
Chen, Nanhai G;
Zhang, Qian;
Le, Ha T;
Aguilar, Richard J;
Yu, Yong A;
Cappello, Joseph;
Szalay, Aladar A

Publication type:

Article

TALENs Targeting HBV: Designer Endonuclease Therapies for Viral Infections.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1819, doi. 10.1038/mt.2013.208

By:

Weber, Nicholas D;
Stone, Daniel;
Jerome, Keith R

Publication type:

Article

Adeno-associated Virus 9 Mediated FKRP Gene Therapy Restores Functional Glycosylation of α-dystroglycan and Improves Muscle Functions.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1832, doi. 10.1038/mt.2013.156

By:

Xu, Lei;
Lu, Pei Juan;
Wang, Chi-Hsien;
Keramaris, Elizabeth;
Qiao, Chunping;
Xiao, Bin;
Blake, Derek J;
Xiao, Xiao;
Lu, Qi Long

Publication type:

Article

NADH-dehydrogenase Type-2 Suppresses Irreversible Visual Loss and Neurodegeneration in the EAE Animal Model of MS.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1876, doi. 10.1038/mt.2013.104

By:

Talla, Venu;
Yu, Hong;
Chou, Tsung-Han;
Porciatti, Vittorio;
Chiodo, Vince;
Boye, Sanford L;
Hauswirth, William W;
Lewin, Alfred S;
Guy, John

Publication type:

Article

Sonia Skarlatos: A Colleague and a Shepherd of Gene Therapy.

Published in:: Molecular Therapy, 2013, v. 21, n. 10, p. 1807, doi. 10.1038/mt.2013.202
Publication type:: Article

Toward RNAi Therapy for the Polyglutamine Disease Machado-Joseph Disease.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1898, doi. 10.1038/mt.2013.144

By:

do Carmo Costa, Maria;
Luna-Cancalon, Katiuska;
Fischer, Svetlana;
Ashraf, Naila S;
Ouyang, Michelle;
Dharia, Rahil M;
Martin-Fishman, Lucas;
Yang, Yemen;
Shakkottai, Vikram G;
Davidson, Beverly L;
Rodríguez-Lebrón, Edgardo;
Paulson, Henry L

Publication type:

Article

Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1909, doi. 10.1038/mt.2013.152

By:

Rodríguez-Lebrón, Edgardo;
Costa, Maria doCarmo;
Luna-Cancalon, Katiuska;
Peron, Therese M;
Fischer, Svetlana;
Boudreau, Ryan L;
Davidson, Beverly L;
Paulson, Henry L

Publication type:

Article

Removing the Immune Response From Muscular Dystrophy Research.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1821, doi. 10.1038/mt.2013.209

By:

Chamberlain, Jeffrey S

Publication type:

Article

DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1958, doi. 10.1038/mt.2013.133

By:

Chi Sabins, Nina;
Taylor, Jennifer L;
Fabian, Kellsye PL;
Appleman, Leonard J;
Maranchie, Jodi K;
Stolz, Donna Beer;
Storkus, Walter J

Publication type:

Article

Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1919, doi. 10.1038/mt.2013.135

By:

Wang, Yuhua;
Xu, Zhenghong;
Guo, Shutao;
Zhang, Lu;
Sharma, Arati;
Robertson, Gavin P;
Huang, Leaf

Publication type:

Article

Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1889, doi. 10.1038/mt.2013.170

By:

Bloom, Kristie;
Ely, Abdullah;
Mussolino, Claudio;
Cathomen, Toni;
Arbuthnot, Patrick

Publication type:

Article

Panorama From the Oncolytic Virotherapy Summit.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1814, doi. 10.1038/mt.2013.207

By:

Pol, Jonathan G;
Marguerie, Monique;
Arulanandam, Rozanne;
Bell, John C;
Lichty, Brian D

Publication type:

Article

Hydrodynamic Delivery of mIL10 Gene Protects Mice From High-fat Diet-induced Obesity and Glucose Intolerance.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1852, doi. 10.1038/mt.2013.125

By:

Gao, Mingming;
Zhang, Chunbo;
Ma, Yongjie;
Bu, Le;
Yan, Linna;
Liu, Dexi

Publication type:

Article

Amalgamating Oncolytic Viruses to Enhance Their Safety, Consolidate Their Killing Mechanisms, and Accelerate Their Spread.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1930, doi. 10.1038/mt.2013.164

By:

Ayala-Breton, Camilo;
Suksanpaisan, Lukkana;
Mader, Emily K;
Russell, Stephen J;
Peng, Kah-Whye

Publication type:

Article