Works matching IS 15250016 AND DT 2012 AND VI 20 AND IP 3

Results: 25

Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 544, doi. 10.1038/mt.2011.216

By:

Gombash, Sara E;
Lipton, Jack W;
Collier, Timothy J;
Madhavan, Lalitha;
Steece-Collier, Kathy;
Cole-Strauss, Allyson;
Terpstra, Brian T;
Spieles-Engemann, Anne L;
Daley, Brian F;
Wohlgenant, Susan L;
Thompson, Valerie B;
Manfredsson, Fredric P;
Mandel, Ronald J;
Sortwell, Caryl E

Publication type:

Article

The Need for Increased Clarity and Transparency in the Regulatory Pathway for Gene Medicines in the European Union.

Published in:

2012

By:

Ylä-Herttuala, Seppo

Publication type:

Editorial

Phase I Trial of 'bi-shRNAifurin/GMCSF DNA/Autologous Tumor Cell' Vaccine (FANG) in Advanced Cancer.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 679, doi. 10.1038/mt.2011.269

By:

Senzer, Neil;
Barve, Minal;
Kuhn, Joseph;
Melnyk, Anton;
Beitsch, Peter;
Lazar, Martin;
Lifshitz, Samuel;
Magee, Mitchell;
Oh, Jonathan;
Mill, Susan W;
Bedell, Cynthia;
Higgs, Candice;
Kumar, Padmasini;
Yu, Yang;
Norvell, Fabienne;
Phalon, Connor;
Taquet, Nicolas;
Rao, Donald D;
Wang, Zhaohui;
Jay, Chris M

Publication type:

Article

Sustained miRNA-mediated Knockdown of Mutant AAT With Simultaneous Augmentation of Wild-type AAT Has Minimal Effect on Global Liver miRNA Profiles.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 590, doi. 10.1038/mt.2011.292

By:

Mueller, Christian;
Tang, Qiushi;
Gruntman, Alisha;
Blomenkamp, Keith;
Teckman, Jeffery;
Song, Lina;
Zamore, Phillip D;
Flotte, Terence R

Publication type:

Article

Escaping the Valley of Death.

Published in:

2012

By:

Frederickson, Robert M

Publication type:

Proceeding

NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 661, doi. 10.1038/mt.2011.261

By:

Lu, Aiping;
Proto, Jonathan D;
Guo, Lulin;
Tang, Ying;
Lavasani, Mitra;
Tilstra, Jeremy S;
Niedernhofer, Laura J;
Wang, Bing;
Guttridge, Denis C;
Robbins, Paul D;
Huard, Johnny

Publication type:

Article

Systemic Delivery of siRNA via LCP Nanoparticle Efficiently Inhibits Lung Metastasis.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 609, doi. 10.1038/mt.2011.270

By:

Yang, Yang;
Li, Jun;
Liu, Feng;
Huang, Leaf

Publication type:

Article

Redirected Antitumor Activity of Primary Human Lymphocytes Transduced With a Fully Human Anti-mesothelin Chimeric Receptor.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 633, doi. 10.1038/mt.2011.256

By:

Lanitis, Evripidis;
Poussin, Mathilde;
Hagemann, Ian S;
Coukos, George;
Sandaltzopoulos, Raphael;
Scholler, Nathalie;
Powell, Daniel J

Publication type:

Article

A General RNA Motif for Cellular Transfection.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 616, doi. 10.1038/mt.2011.277

By:

Magalhães, Maria LB;
Byrom, Michelle;
Yan, Amy;
Kelly, Linsley;
Li, Na;
Furtado, Raquel;
Palliser, Deborah;
Ellington, Andrew D;
Levy, Matthew

Publication type:

Article

Combined Tbet and IL12 Gene Therapy Elicits and Recruits Superior Antitumor Immunity In Vivo.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 644, doi. 10.1038/mt.2011.283

By:

Qu, Yanyan;
Chen, Lu;
Lowe, Devin B;
Storkus, Walter J;
Taylor, Jennifer L

Publication type:

Article

Long-term Persistence of CD4+ but Rapid Disappearance of CD8+ T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 652, doi. 10.1038/mt.2011.286

By:

Engels, Boris;
Chervin, Adam S;
Sant, Andrea J;
Kranz, David M;
Schreiber, Hans

Publication type:

Article

Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 565, doi. 10.1038/mt.2011.268

By:

Karakikes, Ioannis;
Hadri, Lahouaria;
Rapti, Kleopatra;
Ladage, Dennis;
Ishikawa, Kiyotake;
Tilemann, Lisa;
Yi, Geng-Hua;
Morel, Charlotte;
Gwathmey, Judith K;
Zsebo, Krisztina;
Weber, Thomas;
Kawase, Yoshiaki;
Hajjar, Roger J

Publication type:

Article

Long-term Restoration of Cardiac Dystrophin Expression in Golden Retriever Muscular Dystrophy Following rAAV6-mediated Exon Skipping.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 580, doi. 10.1038/mt.2011.264

By:

Bish, Lawrence T;
Sleeper, Meg M;
Forbes, Sean C;
Wang, Bingjing;
Reynolds, Caryn;
Singletary, Gretchen E;
Trafny, Dennis;
Morine, Kevin J;
Sanmiguel, Julio;
Cecchini, Sylvain;
Virag, Tamas;
Vulin, Adeline;
Beley, Cyriaque;
Bogan, Janet;
Wilson, James M;
Vandenborne, Krista;
Kornegay, Joe N;
Walter, Glenn A;
Kotin, Robert M;
Garcia, Luis

Publication type:

Article

Clinical Development of Advanced Therapy Medicinal Products in Europe: Evidence That Regulators Must Be Proactive.

Published in:

2012

By:

Maciulaitis, Romaldas;
D'Apote, Lucia;
Buchanan, Andrew;
Pioppo, Laura;
Schneider, Christian K

Publication type:

Opinion

Self-complementary AAVs Induce More Potent Transgene Product-specific Immune Responses Compared to a Single-stranded Genome.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 572, doi. 10.1038/mt.2011.280

By:

Wu, TeLang;
Töpfer, Katrin;
Lin, Shih-Wen;
Li, Hua;
Bian, Ang;
Zhou, Xiang Y;
High, Katherine A;
Ertl, Hildegund CJ

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2012, v. 20, n. 3, p. 475, doi. 10.1038/mt.2012.17
Publication type:: Article

Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 513, doi. 10.1038/mt.2011.294

By:

Kanasty, Rosemary L;
Whitehead, Kathryn A;
Vegas, Arturo J;
Anderson, Daniel G

Publication type:

Article

In Vivo Delivery of Nucleic Acids via Glycopolymer Vehicles Affords Therapeutic Infarct Size Reduction In Vivo.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 601, doi. 10.1038/mt.2011.267

By:

Tranter, Michael;
Liu, Yemin;
He, Suiwen;
Gulick, James;
Ren, Xiaoping;
Robbins, Jeffrey;
Jones, W. Keith;
Reineke, Theresa M.

Publication type:

Article

An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 555, doi. 10.1038/mt.2011.241

By:

Spies, Elmar;
Reichardt, Wilfried;
Alvarez, Gerardo;
Groettrup, Marcus;
öhlschläger, Peter

Publication type:

Article

Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 669, doi. 10.1038/mt.2011.188

By:

Lang Kuhs, Krystle A;
Ginsberg, Arielle A;
Yan, Jian;
Wiseman, Roger W;
Khan, Amir S;
Sardesai, Niranjan Y;
O'Connor, David H;
Weiner, David B

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2012, v. 20, n. 3, p. 474, doi. 10.1038/mt.2012.16
Publication type:: Article

Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 525, doi. 10.1038/mt.2011.284

By:

Margus, Helerin;
Padari, Kärt;
Pooga, Margus

Publication type:

Article

Correction of Murine Bernard-Soulier Syndrome by Lentivirus-mediated Gene Therapy.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 625, doi. 10.1038/mt.2011.231

By:

Kanaji, Sachiko;
Kuether, Erin L;
Fahs, Scot A;
Schroeder, Jocelyn A;
Ware, Jerry;
Montgomery, Robert R;
Shi, Qizhen

Publication type:

Article

Progress Toward In Vivo Use of siRNAs-II.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 483, doi. 10.1038/mt.2011.263

By:

Rettig, Garrett R;
Behlke, Mark A

Publication type:

Article

Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 534, doi. 10.1038/mt.2011.249

By:

Drinkut, Anja;
Tereshchenko, Yuliya;
Schulz, Jörg B;
Bähr, Mathias;
Kügler, Sebastian

Publication type:

Article

Works matching IS 15250016 AND DT 2012 AND VI 20 AND IP 3

Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model.

The Need for Increased Clarity and Transparency in the Regulatory Pathway for Gene Medicines in the European Union.

Phase I Trial of 'bi-shRNAi<sup>furin</sup>/GMCSF DNA/Autologous Tumor Cell' Vaccine (FANG) in Advanced Cancer.

Sustained miRNA-mediated Knockdown of Mutant AAT With Simultaneous Augmentation of Wild-type AAT Has Minimal Effect on Global Liver miRNA Profiles.

Escaping the Valley of Death.

NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells.

Systemic Delivery of siRNA via LCP Nanoparticle Efficiently Inhibits Lung Metastasis.

Redirected Antitumor Activity of Primary Human Lymphocytes Transduced With a Fully Human Anti-mesothelin Chimeric Receptor.

A General RNA Motif for Cellular Transfection.

Combined Tbet and IL12 Gene Therapy Elicits and Recruits Superior Antitumor Immunity In Vivo.

Long-term Persistence of CD4<sup>+</sup> but Rapid Disappearance of CD8<sup>+</sup> T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity.

Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts.

Long-term Restoration of Cardiac Dystrophin Expression in Golden Retriever Muscular Dystrophy Following rAAV6-mediated Exon Skipping.

Clinical Development of Advanced Therapy Medicinal Products in Europe: Evidence That Regulators Must Be Proactive.

Self-complementary AAVs Induce More Potent Transgene Product-specific Immune Responses Compared to a Single-stranded Genome.

Research Highlights.

Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles.

In Vivo Delivery of Nucleic Acids via Glycopolymer Vehicles Affords Therapeutic Infarct Size Reduction In Vivo.

An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma.

Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses.

In This Issue.

Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery.

Correction of Murine Bernard-Soulier Syndrome by Lentivirus-mediated Gene Therapy.

Progress Toward In Vivo Use of siRNAs-II.

Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery.