Works matching IS 15250016 AND DT 2012 AND VI 20

Results: 307

Targeting Axl With an High-affinity Inhibitory Aptamer.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2291, doi. 10.1038/mt.2012.163

By:

Cerchia, Laura;
Esposito, Carla L;
Camorani, Simona;
Rienzo, Anna;
Stasio, Loredana;
Insabato, Luigi;
Affuso, Andrea;
de Franciscis, Vittorio

Publication type:

Article

AAV9-mediated VEGF-B Gene Transfer Improves Systolic Function in Progressive Left Ventricular Hypertrophy.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2212, doi. 10.1038/mt.2012.145

By:

Huusko, Jenni;
Lottonen, Line;
Merentie, Mari;
Gurzeler, Erika;
Anisimov, Andrey;
Miyanohara, Atsushi;
Alitalo, Kari;
Tavi, Pasi;
Ylä-Herttuala, Seppo

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2012, v. 20, n. 12, p. 2195, doi. 10.1038/mt.2012.239
Publication type:: Article

Nonviral Delivery of Small Interfering RNA Into Pancreas-associated Immune Cells Prevents Autoimmune Diabetes.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2315, doi. 10.1038/mt.2012.190

By:

Leconet, Wilhem;
Petit, Pierre;
Peraldi-Roux, Sylvie;
Bresson, Damien

Publication type:

Article

Adenovirus Immunity: X Marks the Spot.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2197, doi. 10.1038/mt.2012.240

By:

Suzuki, Masataka;
Rooney, Cliona M

Publication type:

Article

Buffering Capacity and Size of siRNA Polyplexes Influence Cytokine Levels.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2282, doi. 10.1038/mt.2012.206

By:

Leng, Qixin;
Chou, Szu-Ting;
Scaria, Puthupparampil V;
Woodle, Martin C;
Mixson, A James

Publication type:

Article

Inflammation, Apoptosis, and Necrosis Induced by Neoadjuvant Fas Ligand Gene Therapy Improves Survival of Dogs With Spontaneous Bone Cancer.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2234, doi. 10.1038/mt.2012.149

By:

Modiano, Jaime F;
Bellgrau, Donald;
Cutter, Gary R;
Lana, Susan E;
Ehrhart, Nicole P;
Ehrhart, EJ;
Wilke, Vicki L;
Charles, J Brad;
Munson, Sibyl;
Scott, Milcah C;
Pozniak, John;
Carlson, Cathy S;
Schaack, Jerome;
Duke, Richard C

Publication type:

Article

European Union Support of Gene Therapy Research: A Success Story.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2191, doi. 10.1038/mt.2012.242

By:

Gancberg, David;
Kessler, Charles;
Hoeveler, Arnd;
Draghia-Akli, Ruxandra

Publication type:

Article

Targeted Expression of miR-34a Using the T-VISA System Suppresses Breast Cancer Cell Growth and Invasion.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2326, doi. 10.1038/mt.2012.201

By:

Li, Laisheng;
Xie, Xinhua;
Luo, Jinmei;
Liu, Min;
Xi, Shaoyan;
Guo, Jiaoli;
Kong, Yanan;
Wu, Minqing;
Gao, Jie;
Xie, Zeming;
Tang, Jun;
Wang, Xi;
Wei, Weidong;
Yang, Mingtian;
Hung, Mien-Chie;
Xie, Xiaoming

Publication type:

Article

CD166pos Subpopulation From Differentiated Human ES and iPS Cells Support Repair of Acute Lung Injury.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2335, doi. 10.1038/mt.2012.182

By:

Soh, Boon Seng;
Zheng, Dahai;
Li Yeo, Julie Su;
Yang, Henry He;
Ng, Shi Yan;
Wong, Lan Hiong;
Zhang, Wencai;
Li, Pin;
Nichane, Massimo;
Asmat, Atasha;
Wong, Poo Sing;
Wong, Peng Cheang;
Su, Lin Lin;
Mantalaris, Sakis A;
Lu, Jia;
Xian, Wa;
McKeon, Frank;
Chen, Jianzhu;
Lim, Elaine Hsuen;
Lim, Bing

Publication type:

Article

Targeting TCTP as a New Therapeutic Strategy in Castration-resistant Prostate Cancer.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2244, doi. 10.1038/mt.2012.155

By:

Baylot, Virginie;
Katsogiannou, Maria;
Andrieu, Claudia;
Taieb, David;
Acunzo, Julie;
Giusiano, Sophie;
Fazli, Ladan;
Gleave, Martin;
Garrido, Carmen;
Rocchi, Palma

Publication type:

Article

A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart.

Published in:: Molecular Therapy, 2012, v. 20, n. 12, p. 2370, doi. 10.1038/mt.2012.254
Publication type:: Article

Human Erythropoietin Gene Delivery Using an Arginine-grafted Bioreducible Polymer System.

Published in:: Molecular Therapy, 2012, v. 20, n. 12, p. 2369, doi. 10.1038/mt.2012.253
Publication type:: Article

A Tumor-stroma Targeted Oncolytic Adenovirus Replicated in Human Ovary Cancer Samples and Inhibited Growth of Disseminated Solid Tumors in Mice.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2222, doi. 10.1038/mt.2012.147

By:

Lopez, M Veronica;
Rivera, Angel A;
Viale, Diego L;
Benedetti, Lorena;
Cuneo, Nicasio;
Kimball, Kristopher J;
Wang, Minghui;
Douglas, Joanne T;
Zhu, Zeng B;
Bravo, Alicia I;
Gidekel, Manuel;
Alvarez, Ronald D;
Curiel, David T;
Podhajcer, Osvaldo L

Publication type:

Article

Robust Suppression of HIV Replication by Intracellularly Expressed Reverse Transcriptase Aptamers Is Independent of Ribozyme Processing.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2304, doi. 10.1038/mt.2012.158

By:

Lange, Margaret J;
Sharma, Tarun K;
Whatley, Angela S;
Landon, Linda A;
Tempesta, Michael A;
Johnson, Marc C;
Burke, Donald H

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2012, v. 20, n. 12, p. 2194, doi. 10.1038/mt.2012.238
Publication type:: Article

Ad5:Ad48 Hexon Hypervariable Region Substitutions Lead to Toxicity and Increased Inflammatory Responses Following Intravenous Delivery.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2268, doi. 10.1038/mt.2012.162

By:

Coughlan, Lynda;
Bradshaw, Angela C;
Parker, Alan L;
Robinson, Hollie;
White, Katie;
Custers, Jerome;
Goudsmit, Jaap;
Van Roijen, Nico;
Barouch, Dan H;
Nicklin, Stuart A;
Baker, Andrew H

Publication type:

Article

ChAd63-MVA-vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2355, doi. 10.1038/mt.2012.223

By:

Sheehy, Susanne H;
Duncan, Christopher JA;
Elias, Sean C;
Choudhary, Prateek;
Biswas, Sumi;
Halstead, Fenella D;
Collins, Katharine A;
Edwards, Nick J;
Douglas, Alexander D;
Anagnostou, Nicholas A;
Ewer, Katie J;
Havelock, Tom;
Mahungu, Tabitha;
Bliss, Carly M;
Miura, Kazutoyo;
Poulton, Ian D;
Lillie, Patrick J;
Antrobus, Richard D;
Berrie, Eleanor;
Moyle, Sarah

Publication type:

Article

Mesenchymal Stromal Cells Treatment Attenuates Dry Eye in Patients With Chronic Graft-versus-host Disease.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2347, doi. 10.1038/mt.2012.208

By:

Weng, Jianyu;
He, Chang;
Lai, Peilong;
Luo, Chenwei;
Guo, Rong;
Wu, Suijing;
Geng, Suxia;
Xiangpeng, Andy;
Liu, Xialin;
Du, Xin

Publication type:

Article

Still Seeking an Effective 'One-Two' Malaria Vaccine Punch.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2198, doi. 10.1038/mt.2012.241

By:

Smith, Joseph D;
Sack, Brandon K

Publication type:

Article

Pharmacological Enhancement of α-Glucosidase by the Allosteric Chaperone N-acetylcysteine.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2201, doi. 10.1038/mt.2012.152

By:

Porto, Caterina;
Ferrara, Maria C;
Meli, Massimiliano;
Acampora, Emma;
Avolio, Valeria;
Rosa, Margherita;
Cobucci-Ponzano, Beatrice;
Colombo, Giorgio;
Moracci, Marco;
Andria, Generoso;
Parenti, Giancarlo

Publication type:

Article

rAAV-Mediated Tumorigenesis: Still Unresolved After an AAV Assault.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2014, doi. 10.1038/mt.2012.220

By:

Valdmanis, Paul N;
Lisowski, Leszek;
Kay, Mark A

Publication type:

Article

Chemoselection of Allogeneic HSC After Murine Neonatal Transplantation Without Myeloablation or Post-transplant Immunosuppression.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2180, doi. 10.1038/mt.2012.136

By:

Falahati, Rustom;
Zhang, Jianqing;
Flebbe-Rehwaldt, Linda;
Shi, Yimin;
Gerson, Stanton L;
Gaensler, Karin ML

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2012, v. 20, n. 11, p. 2009, doi. 10.1038/mt.2012.217
Publication type:: Article

Intravenous Mesenchymal Stem Cells Prevented Rejection of Allogeneic Corneal Transplants by Aborting the Early Inflammatory Response.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2143, doi. 10.1038/mt.2012.165

By:

Oh, Joo Youn;
Lee, Ryang Hwa;
Yu, Ji Min;
Ko, Jung Hwa;
Lee, Hyun Ju;
Ko, Ah Young;
Roddy, Gavin W;
Prockop, Darwin J

Publication type:

Article

Terminal Differentiation of Cardiac and Skeletal Myocytes Induces Permissivity to AAV Transduction by Relieving Inhibition Imposed by DNA Damage Response Proteins.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2087, doi. 10.1038/mt.2012.144

By:

Lovric, Jasmina;
Mano, Miguel;
Zentilin, Lorena;
Eulalio, Ana;
Zacchigna, Serena;
Giacca, Mauro

Publication type:

Article

A TLR and Non-TLR Mediated Innate Response to Lentiviruses Restricts Hepatocyte Entry and Can be Ameliorated by Pharmacological Blockade.

Published in:

Molecular Therapy, 2012, v. 20, n. 12, p. 2257, doi. 10.1038/mt.2012.150

By:

Agudo, Judith;
Ruzo, Albert;
Kitur, Kipyegon;
Sachidanandam, Ravi;
Blander, J Magarian;
Brown, Brian D

Publication type:

Article

Proinflammatory Macrophages Enhance the Regenerative Capacity of Human Myoblasts by Modifying Their Kinetics of Proliferation and Differentiation.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2168, doi. 10.1038/mt.2012.189

By:

Bencze, Maximilien;
Negroni, Elisa;
Vallese, Denis;
Yacoub-Youssef, Houda;
Chaouch, Soraya;
Wolff, Annie;
Aamiri, Ahmed;
Di Santo, James P;
Chazaud, Bénédicte;
Butler-Browne, Gillian;
Savino, Wilson;
Mouly, Vincent;
Riederer, Ingo

Publication type:

Article

Muscle Function Recovery in Golden Retriever Muscular Dystrophy After AAV1-U7 Exon Skipping.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2120, doi. 10.1038/mt.2012.181

By:

Vulin, Adeline;
Barthélémy, Inès;
Goyenvalle, Aurélie;
Thibaud, Jean-Laurent;
Beley, Cyriaque;
Griffith, Graziella;
Benchaouir, Rachid;
le Hir, Maëva;
Unterfinger, Yves;
Lorain, Stéphanie;
Dreyfus, Patrick;
Voit, Thomas;
Carlier, Pierre;
Blot, Stéphane;
Garcia, Luis

Publication type:

Article

Oral Administration of Recombinant Adeno-associated Virus-mediated Bone Morphogenetic Protein-7 Suppresses CCl4-induced Hepatic Fibrosis in Mice.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2043, doi. 10.1038/mt.2012.148

By:

Hao, Zhi-Ming;
Cai, Min;
Lv, Yi-Fei;
Huang, Yan-Hua;
Li, Hong-Hong

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2012, v. 20, n. 11, p. 2008, doi. 10.1038/mt.2012.216
Publication type:: Article

Exon 45 Skipping Through U1-snRNA Antisense Molecules Recovers the Dys-nNOS Pathway and Muscle Differentiation in Human DMD Myoblasts.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2134, doi. 10.1038/mt.2012.178

By:

Cazzella, Valentina;
Martone, Julie;
Pinnarò, Chiara;
Santini, Tiziana;
Twayana, Shyam Sundar;
Sthandier, Olga;
D'Amico, Adele;
Ricotti, Valeria;
Bertini, Enrico;
Muntoni, Francesco;
Bozzoni, Irene

Publication type:

Article

The Extragenic Spacer Length Between the 5′ and 3′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2111, doi. 10.1038/mt.2012.65

By:

Lu, Jiamiao;
Zhang, Feijie;
Xu, Siqun;
Fire, Andrew Z;
Kay, Mark A

Publication type:

Article

GOLGA2/GM130, cis-Golgi Matrix Protein, is a Novel Target of Anticancer Gene Therapy.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2052, doi. 10.1038/mt.2012.125

By:

Chang, Seung-Hee;
Hong, Seong-Ho;
Jiang, Hu-Lin;
Minai-Tehrani, Arash;
Yu, Kyeong-Nam;
Lee, Jae-Ho;
Kim, Ji-Eun;
Shin, Ji-Young;
Kang, Bitna;
Park, Sungjin;
Han, Kiwon;
Chae, Chanhee;
Cho, Myung-Haing

Publication type:

Article

Patterns of scAAV Vector Insertion Associated With Oncogenic Events in a Mouse Model for Genotoxicity.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2098, doi. 10.1038/mt.2012.197

By:

Rosas, Lucia E;
Grieves, Jessica L;
Zaraspe, Kimberly;
La Perle, Krista MD;
Fu, Haiyan;
McCarty, Douglas M

Publication type:

Article

An Oncolytic Adenovirus Enhanced for Toll-like Receptor 9 Stimulation Increases Antitumor Immune Responses and Tumor Clearance.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2076, doi. 10.1038/mt.2012.137

By:

Cerullo, Vincenzo;
Diaconu, Iulia;
Romano, Valentina;
Hirvinen, Mari;
Ugolini, Matteo;
Escutenaire, Sophie;
Holm, Sirkka-Liisa;
Kipar, Anja;
Kanerva, Anna;
Hemminki, Akseli

Publication type:

Article

Introducing a New ASGCT Forum for Publication of Methodology and Clinical Development in Gene, Cell, and Oligonucleotide Therapies.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2005, doi. 10.1038/mt.2012.215

By:

Frederickson, Robert M;
Brenner, Malcolm K

Publication type:

Article

Extended Normal Life After AAVrh10-mediated Gene Therapy in the Mouse Model of Krabbe Disease.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2031, doi. 10.1038/mt.2012.153

By:

Rafi, Mohammad A;
Rao, Han Zhi;
Luzi, Paola;
Curtis, Mark T;
Wenger, David A

Publication type:

Article

Converting Pathological Cells to Therapeutic Ones: An Odyssey Through Pluripotency.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2012, doi. 10.1038/mt.2012.219

By:

Vilquin, Jean-Thomas

Publication type:

Article

Phage Display-directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2064, doi. 10.1038/mt.2012.132

By:

Desimmie, Belete A;
Humbert, Michael;
Lescrinier, Eveline;
Hendrix, Jelle;
Vets, Sofie;
Gijsbers, Rik;
Ruprecht, Ruth M;
Dietrich, Ursula;
Debyser, Zeger;
Christ, Frauke

Publication type:

Article

RNAi Joins the 'Singles Club'.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2010, doi. 10.1038/mt.2012.218

By:

Peschansky, Veronica J.;
Liang, Zicai;
Wahlestedt, Claes

Publication type:

Article

A New Vision of Mesenchymal Stromal Cells.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2017, doi. 10.1038/mt.2012.221

By:

Hurwitz, Richard L

Publication type:

Article

Restoration of Vision in the pde6β-deficient Dog, a Large Animal Model of Rod-cone Dystrophy.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2019, doi. 10.1038/mt.2012.134

By:

Petit, Lolita;
Lhériteau, Elsa;
Weber, Michel;
Le Meur, Guylène;
Deschamps, Jack-Yves;
Provost, Nathalie;
Mendes-Madeira, Alexandra;
Libeau, Lyse;
Guihal, Caroline;
Colle, Marie-Anne;
Moullier, Philippe;
Rolling, Fabienne

Publication type:

Article

Myoblasts Derived From Normal hESCs and Dystrophic hiPSCs Efficiently Fuse With Existing Muscle Fibers Following Transplantation.

Published in:

Molecular Therapy, 2012, v. 20, n. 11, p. 2153, doi. 10.1038/mt.2012.188

By:

Goudenege, Sébastien;
Lebel, Carl;
Huot, Nicolas B;
Dufour, Christine;
Fujii, Isao;
Gekas, Jean;
Rousseau, Joël;
Tremblay, Jacques P

Publication type:

Article

1α,25(OH)2-Vitamin D3 Increases Dysferlin Expression in vitro and in a Human Clinical Trial.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1988, doi. 10.1038/mt.2012.156

By:

Luna, Noemi De;
Díaz-Manera, Jordi;
Paradas, Carmen;
Iturriaga, Cristina;
Rojas-García, Ricardo;
Araque, Josefa;
Genebriera, Mireia;
Gich, Ignasi;
Illa, Isabel;
Gallardo, Eduard

Publication type:

Article

Conditional Negative Selection of Gene-Modified Hematopoietic Stem Cells.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1841, doi. 10.1038/mt.2012.195

By:

Baum, Christopher

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2012, v. 20, n. 10, p. 1834, doi. 10.1038/mt.2012.198
Publication type:: Article

Thymidine Kinase Suicide Gene-mediated Ganciclovir Ablation of Autologous Gene-modified Rhesus Hematopoiesis.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1932, doi. 10.1038/mt.2012.166

By:

Barese, Cecilia N;
Krouse, Allen E;
Metzger, Mark E;
King, Connor A;
Traversari, Catia;
Marini, Frank C;
Donahue, Robert E;
Dunbar, Cynthia E

Publication type:

Article

Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1912, doi. 10.1038/mt.2012.164

By:

Lisowski, Leszek;
Lau, Ashley;
Wang, Zhongya;
Zhang, Yue;
Zhang, Feijie;
Grompe, Markus;
Kay, Mark A

Publication type:

Article

AAV Vectors for the Nucleolus.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1842, doi. 10.1038/mt.2012.193

By:

Russell, David W

Publication type:

Article