Works matching IS 15250016 AND DT 2011 AND VI 19 AND IP 2

Results: 30

Sustained Enzymatic Correction by rAAV-Mediated Liver Gene Therapy Protects Against Induced Motor Neuropathy in Acute Porphyria Mice.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 243, doi. 10.1038/mt.2010.210

By:

Unzu, Carmen;
Sampedro, Ana;
Mauleón, Itsaso;
Alegre, Manuel;
Beattie, Stuart G.;
de Salamanca, Rafael Enríquez;
Snapper, Jolanda;
Twisk, Jaap;
Petry, Harald;
González-Aseguinolaza, Gloria;
Artieda, Julio;
Rodríguez-Pena, María Sol;
Prieto, Jesús;
Fontanellas, Antonio

Publication type:

Article

The FGF-2-Derived Peptide FREG Inhibits Melanoma Growth In Vitro and In Vivo.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 266, doi. 10.1038/mt.2010.211

By:

Aguzzi, Maria S;
Faraone, Debora;
D'Arcangelo, Daniela;
De Marchis, Francesco;
Toietta, Gabriele;
Ribatti, Domenico;
Parazzoli, Alberto;
Colombo, Paolo;
Capogrossi, Maurizio C;
Facchiano, Antonio

Publication type:

Article

Neuroprotection by Gene Therapy Targeting Mutant SOD1 in Individual Pools of Motor Neurons Does not Translate Into Therapeutic Benefit in fALS Mice.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 274, doi. 10.1038/mt.2010.260

By:

Towne, Chris;
Setola, Veronica;
Schneider, Bernard L.;
Aebischer, Patrick

Publication type:

Article

AAV6-Mediated Gene Silencing fALS Short.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 231, doi. 10.1038/mt.2010.306

By:

Mandel, Ronald J.;
Lowenstein, Pedro R.;
Byrne, Barry J.

Publication type:

Article

Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 260, doi. 10.1038/mt.2010.230

By:

Lukason, Michael;
DuFresne, Elizabeth;
Rubin, Hillard;
Pechan, Peter;
Qiuhong Li;
Kim, Ivana;
Kiss, Szilard;
Flaxel, Christina;
Collins, Margaret;
Miller, Joan;
Hauswirth, William;
MacLachlan, Timothy;
Wadsworth, Samuel;
Scaria, Abraham

Publication type:

Article

Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood-Brain Barrier Endothelial Cells In Vitro.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 318, doi. 10.1038/mt.2010.236

By:

Georgieva, Julia V.;
Kalicharan, Dharamdajal;
Couraud, Pierre-Olivier;
Romero, Ignacio A.;
Weksler, Babette;
Hoekstra, Dick;
Zuhorn, Inge S.

Publication type:

Article

Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 395, doi. 10.1038/mt.2010.254

By:

Akao, Yukihiro;
Iio, Akio;
Itoh, Tomohiro;
Noguchi, Shunsuke;
Itoh, Yuko;
Ohtsuki, Yoshinori;
Naoe, Tomoki

Publication type:

Article

Is Human Cell Therapy Research Caught in a Mousetrap?

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 224, doi. 10.1038/mt.2010.304

By:

John Barrett, A.;
Joseph Melenhorst, J.

Publication type:

Article

Elimination Pathways of Systemically Delivered siRNA.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 381, doi. 10.1038/mt.2010.266

By:

Yuanyu Huang;
Junmei Hong;
Shuquan Zheng;
Yi Ding;
Shutao Guo;
Hongyan Zhang;
Xiuqin Zhang;
Quan Du;
Zicai Liang

Publication type:

Article

Lentiviral Vector Platform for Production of Bioengineered Recombinant Coagulation Factor VIII.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 302, doi. 10.1038/mt.2010.239

By:

Spencer, H. Trent;
Denning, Gabriela;
Gautney, Richard E.;
Dropulic, Boro;
Roy, Andre J.;
Baranyi, Lajos;
Gangadharan, Bagirath;
Parker, Ernest T.;
Lollar, Pete;
Doering, Christopher B.

Publication type:

Article

Ex-vivo Gene Therapy Restores LEKTI Activity and Corrects the Architecture of Netherton Syndrome-derived Skin Grafts.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 408, doi. 10.1038/mt.2010.201

By:

Wei-Li Di;
Larcher, Fernado;
Semenova, Ekaterina;
Talbot, Gill E.;
Harper, John I;
Del Rio, Marcela;
Thrasher, Adrian J.;
Qasim, Waseem

Publication type:

Article

CNS-targeted Viral Delivery of G-CSF in an Animal Model for ALS: Improved Efficacy and Preservation of the Neuromuscular Unit.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 284, doi. 10.1038/mt.2010.271

By:

Henriques, Alexandre;
Pitzer, Claudia;
Dittgen, Tanjew;
Klugmann, Matthias;
Dupuis, Luc;
Schneider, Armin

Publication type:

Article

Application of Phi29 Motor pRNA for Targeted Therapeutic Delivery of siRNA Silencing Metallothionein-IIA and Survivin in Ovarian Cancers.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 386, doi. 10.1038/mt.2010.243

By:

Tarapore, Pheruza;
Yi Shu;
Peixuan Guo;
Shuk-Mei Ho

Publication type:

Article

Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 400, doi. 10.1038/mt.2010.241

By:

Inamura, Mitsuru;
Kawabata, Kenji;
Takayama, Kazuo;
Tashiro, Katsuhisa;
Sakurai, Fuminori;
Katayama, Kazufumi;
Toyoda, Masashi;
Akutsu, Hidenori;
Miyagawa, Yoshitaka;
Okita, Hajime;
Kiyokawa, Nobutaka;
Umezawa, Akihiro;
Hayakawa, Takao;
Furue, Miho K;
Mizuguchi, Hiroyuki

Publication type:

Article

Direct Conversion of Skin Cells into Blood: Alchemy or Science?

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 227, doi. 10.1038/mt.2010.291

By:

King, Katherine Y.;
Goodell, Margaret A.

Publication type:

Article

Vaccine-induced T cells Provide Partial Protection Against High-dose Rectal SIVmac239 Challenge of Rhesus Macaques.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 417, doi. 10.1038/mt.2010.238

By:

Lasaro, Marcio O.;
Haut, Larissa H.;
Xiangyang Zhou;
Zhiquan Xiang;
Dongming Zhou;
Yan Li;
Giles-Davis, Wynetta;
Hua Li;
Engram, Jessica C.;
DiMenna, Lauren J.;
Bian, Ang;
Sazanovich, Marina;
Parzych, Elizabeth M.;
Kurupati, Raj;
Small, Juliana C.;
Te-Lang Wu;
Leskowitz, Rachel M.;
Klatt, Nicole R.;
Brenchley, Jason M.;
Garber, David A.

Publication type:

Article

Preclinical Safety Evaluation of AAV2-sFLT01- A Gene Therapy for Age-related Macular Degeneration.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 326, doi. 10.1038/mt.2010.258

By:

MacLachlan, Timothy K.;
Lukason, Michael;
Collins, Margaret;
Munger, Robert;
Isenberger, Elisabete;
Rogers, Cindy;
Malatos, Shana;
DuFresne, Elizabeth;
Morris, James;
Calcedo, Roberto;
Veres, Gabor;
Scaria, Abraham;
Andrews, Laura;
Wadsworth, Samuel

Publication type:

Article

MITF-siRNA Formulation Is a Safe and Effective Therapy for Human Melasma.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 362, doi. 10.1038/mt.2010.263

By:

Xiang Yi;
Guang Zhao;
Hongjie Zhang;
Di Guan;
Rusong Meng;
Yingyu Zhang;
Qingqi Yang;
Henming Jia;
Kejun Dou;
Chui Liu;
Fangyuan Que;
Yin, James Q.

Publication type:

Article

Antifibrotic Effect of MMP13-encoding Plasmid DNA Delivered Using Polyethylenimine Shielded With Hyaluronic Acid.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 355, doi. 10.1038/mt.2010.262

By:

Eun-Joong Kim;
Hee-Jeong Cho;
Daeui Park;
Ji Yeon Kim;
Young Bong Kim;
Tae Gwan Park;
Chang-Koo Shim;
Yu-Kyoung Oh

Publication type:

Article

Gene Therapy Moves Forward in 2010.

Published in:

2011

By:

Ylä-Herttuala, Seppo

Publication type:

Conference Paper/Materials

Adaptive Antiviral Immunity Is a Determinant of the Therapeutic Success of Oncolytic Virotherapy.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 335, doi. 10.1038/mt.2010.264

By:

Sobol, Paul T.;
Boudreau, Jeanette E.;
Stephenson, Kyle;
Yonghong Wan;
Lichty, Brian D.;
Mossman, Karen L.

Publication type:

Article

Poly(oligo-D-arginine) With Internal Disulfide Linkages as a Cytoplasm-sensitive Carrier for siRNA Delivery.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 372, doi. 10.1038/mt.2010.242

By:

Young-Wook Won;
Sun-Mi Yoon;
Kyung-Mi Lee;
Yong-Hee Kim

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2011, v. 19, n. 2, p. 222, doi. 10.1038/mt.2010.309
Publication type:: Article

Research Highlights.

Published in:: 2011
Publication type:: Abstract

Long-term Retinal Function and Structure Rescue Using Capsid Mutant AAV8 Vector in the rd10 Mouse, a Model of Recessive Retinitis Pigmentosa.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 234, doi. 10.1038/mt.2010.273

By:

Ji-jing Pang;
Xufeng Dai;
Boye, Shannon E.;
Barone, Ilaria;
Boye, Sanford L.;
Song Mao;
Everhart, Drew;
Dinculescu, Astra;
Li .Liu;
Umino, Yumiko;
Bo .Lei;
Bo .Chang;
Barlow, Robert;
Strettoi, Enrica;
Hauswirth, William W.

Publication type:

Article

Safe, Efficient, and Reproducible Gene Therapy of the Brain in the Dog Models of Sanfilippo and Hurler Syndromes.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 251, doi. 10.1038/mt.2010.265

By:

Ellinwood, N. Matthew;
Ausseil, Jérôme;
Desmaris, Nathalie;
Bigou, Stéphanie;
Song Liu;
Jens, Jackie K.;
Snella, Elizabeth M.;
Mohammed, Eman E. A.;
Thomson, Christopher B.;
Raoul, Sylvie;
Joussemet, Béatrice;
Roux, Françoise;
Chérel, Yan;
Lajat, Yaouen;
Piraud, Monique;
Benchaouir, Rachid;
Hermening, Stephan;
Petry, Harald;
Froissart, Roseline;
Tardieu, Marc

Publication type:

Article

Solving the Problem of γ-Retroviral Vectors Containing Long Terminal Repeats.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 229, doi. 10.1038/mt.2010.305

By:

Persons, Derek A.;
Baum, Christopher

Publication type:

Article

Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 345, doi. 10.1038/mt.2010.261

By:

Malerba, Alberto;
Sharp, Paul S.;
Graham, Ian R.;
Arechavala-Gomeza, Virginia;
Foster, Keith;
Muntoni, Francesco;
Wells, Dominic J.;
Dickson, George

Publication type:

Article

Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 293, doi. 10.1038/mt.2010.234

By:

Petrs-Silva, Hilda;
Dinculescu, Astra;
Qiuhong Li;
Wen-Tao Deng;
Ji-jing Pang;
Seok-Hong Min;
Chiodo, Vince;
Neeley, Andy W.;
Govindasamy, Lakshmanan;
Bennett, Antonette;
Agbandje-McKenna, Mavis;
Li Zhong;
Baozheng Li;
Jayandharan, Giridhara R.;
Srivastava, Arun;
Lewin, Alfred S.;
Hauswirth, William W.

Publication type:

Article

Prevention of Diabetic Neuropathy by Regulatable Expression of HSV-Mediated Erythropoietin.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 310, doi. 10.1038/mt.2010.215

By:

Zetang Wu;
Mata, Marina;
Fink, David J.

Publication type:

Article