Works matching IS 15250016 AND DT 2011 AND VI 19

Results: 306

The Development of a Novel Cancer Immunotherapeutic Platform Using Tumor-targeting Mesenchymal Stem Cells and a Protein Vaccine.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2249, doi. 10.1038/mt.2011.152

By:

Wei, Hon-Jian;
Wu, Alexander TH;
Hsu, Chung-Huei;
Lin, Yi-Ping;
Cheng, Wen-Fang;
Su, Ching-Hua;
Chiu, Wen-Ta;
Whang-Peng, Jacqueline;
Douglas, Frank L;
Deng, Win-Ping

Publication type:

Article

ATP7A Gene Addition to the Choroid Plexus Results in Long-term Rescue of the Lethal Copper Transport Defect in a Menkes Disease Mouse Model.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2114, doi. 10.1038/mt.2011.143

By:

Donsante, Anthony;
Yi, Ling;
Zerfas, Patricia M;
Brinster, Lauren R;
Sullivan, Patricia;
Goldstein, David S;
Prohaska, Joseph;
Centeno, Jose A;
Rushing, Elisabeth;
Kaler, Stephen G

Publication type:

Article

Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2258, doi. 10.1038/mt.2011.167

By:

Gerdemann, Ulrike;
Katari, Usha;
Christin, Anne S;
Cruz, Conrad R;
Tripic, Tamara;
Rousseau, Alexandra;
Gottschalk, Stephen M;
Savoldo, Barbara;
Vera, Juan F;
Heslop, Helen E;
Brenner, Malcolm K;
Bollard, Catherine M;
Rooney, Cliona M;
Leen, Ann M

Publication type:

Article

Microarray Analysis of Gene Expression Profiles in Cells Transfected With Nonviral Vectors.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2144, doi. 10.1038/mt.2011.161

By:

Plautz, Sarah A;
Boanca, Gina;
Riethoven, Jean-Jack M;
Pannier, Angela K

Publication type:

Article

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2186, doi. 10.1038/mt.2011.190

By:

Basha, Genc;
Novobrantseva, Tatiana I;
Rosin, Nicole;
Tam, Yuen Yi C;
Hafez, Ismail M;
Wong, Matthew K;
Sugo, Tsukasa;
Ruda, Vera M;
Qin, June;
Klebanov, Boris;
Ciufolini, Marco;
Akinc, Akin;
Tam, Ying K;
Hope, Michael J;
Cullis, Pieter R

Publication type:

Article

Gene Therapy for SCID-X1: Focus on Clinical Data.

Published in:

2011

By:

Baum, Christopher

Publication type:

Editorial

Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2169, doi. 10.1038/mt.2011.185

By:

Boudreau, Ryan L;
Spengler, Ryan M;
Davidson, Beverly L

Publication type:

Article

Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2228, doi. 10.1038/mt.2011.207

By:

Zhou, Jiehua;
Neff, C Preston;
Liu, Xiaoxuan;
Zhang, Jane;
Li, Haitang;
Smith, David D;
Swiderski, Piotr;
Aboellail, Tawfik;
Huang, Yuanyu;
Du, Quan;
Liang, Zicai;
Peng, Ling;
Akkina, Ramesh;
Rossi, John J

Publication type:

Article

Gene Transfer Using HACs: A Key Step Closer to Ex Vivo Gene Therapy Using Autologous Gene-Corrected Cells to Treat Muscular Dystrophy.

Published in:

2011

By:

Tremblay, Jacques P;
Frederickson, Robert M

Publication type:

Opinion

Stabilization of Expanded (CTG)•(CAG) Repeats by Antisense Oligonucleotides.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2222, doi. 10.1038/mt.2011.191

By:

Nakamori, Masayuki;
Gourdon, Geneviève;
Thornton, Charles A

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2011, v. 19, n. 12, p. 2107, doi. 10.1038/mt.2011.247
Publication type:: Article

Efficient In Vivo Delivery of siRNA Into Brain Capillary Endothelial Cells Along With Endogenous Lipoprotein.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2213, doi. 10.1038/mt.2011.186

By:

Kuwahara, Hiroya;
Nishina, Kazutaka;
Yoshida, Kie;
Nishina, Tomoko;
Yamamoto, Mariko;
Saito, Yukari;
Piao, Wenying;
Yoshida, Masayuki;
Mizusawa, Hidehiro;
Yokota, Takanori

Publication type:

Article

lncRNAs: Finding the Forest Among the Trees?

Published in:

2011

By:

Dinger, Marcel E

Publication type:

Opinion

Combining mTor Inhibitors With Rapamycin-resistant T Cells: A Two-pronged Approach to Tumor Elimination.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2239, doi. 10.1038/mt.2011.179

By:

Huye, Leslie E;
Nakazawa, Yozo;
Patel, Mayuri P;
Yvon, Eric;
Sun, Jiali;
Savoldo, Barbara;
Wilson, Matthew H;
Dotti, Gianpietro;
Rooney, Cliona M

Publication type:

Article

Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2178, doi. 10.1038/mt.2011.201

By:

Carroll, Jeffrey B;
Warby, Simon C;
Southwell, Amber L;
Doty, Crystal N;
Greenlee, Sarah;
Skotte, Niels;
Hung, Gene;
Bennett, C Frank;
Freier, Susan M;
Hayden, Michael R

Publication type:

Article

PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2133, doi. 10.1038/mt.2011.131

By:

Nakazawa, Yozo;
Huye, Leslie E;
Salsman, Vita S;
Leen, Ann M;
Ahmed, Nabil;
Rollins, Lisa;
Dotti, Gianpietro;
Gottschalk, Stephen M;
Wilson, Matthew H;
Rooney, Cliona M

Publication type:

Article

Interfering With Tumor Pathways That Augment Viral Oncolysis.

Published in:

2011

By:

Bell, John C

Publication type:

Opinion

In This Issue.

Published in:: 2011
Publication type:: Abstract

Selective Therapeutic Targeting of the Anaplastic Lymphoma Kinase With Liposomal siRNA Induces Apoptosis and Inhibits Angiogenesis in Neuroblastoma.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2201, doi. 10.1038/mt.2011.142

By:

Di Paolo, Daniela;
Ambrogio, Chiara;
Pastorino, Fabio;
Brignole, Chiara;
Martinengo, Cinzia;
Carosio, Roberta;
Loi, Monica;
Pagnan, Gabriella;
Emionite, Laura;
Cilli, Michele;
Ribatti, Domenico;
Allen, Theresa M;
Chiarle, Roberto;
Ponzoni, Mirco;
Perri, Patrizia

Publication type:

Article

Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2124, doi. 10.1038/mt.2011.175

By:

Watkins, Catherine L;
Sayers, Edward J;
Allender, Chris;
Barrow, David;
Fegan, Christopher;
Brennan, Paul;
Jones, Arwyn T

Publication type:

Article

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2163, doi. 10.1038/mt.2011.206

By:

Moschos, Sterghios A;
Frick, Manfred;
Taylor, Bruce;
Turnpenny, Paul;
Graves, Helen;
Spink, Karen G;
Brady, Kevin;
Lamb, David;
Collins, David;
Rockel, Thomas D;
Weber, Markus;
Lazari, Ovadia;
Perez-Tosar, Luis;
Fancy, Sally A;
Lapthorn, Chris;
Green, Martin X;
Evans, Steve;
Selby, Matthew;
Jones, Gareth;
Jones, Lyn

Publication type:

Article

Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2152, doi. 10.1038/mt.2011.219

By:

McBride, Jodi L;
Pitzer, Mark R;
Boudreau, Ryan L;
Dufour, Brett;
Hobbs, Theodore;
Ojeda, Sergio R;
Davidson, Beverly L

Publication type:

Article

Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2269, doi. 10.1038/mt.2011.176

By:

Sheehy, Susanne H;
Duncan, Christopher JA;
Elias, Sean C;
Collins, Katharine A;
Ewer, Katie J;
Spencer, Alexandra J;
Williams, Andrew R;
Halstead, Fenella D;
Moretz, Samuel E;
Miura, Kazutoyo;
Epp, Christian;
Dicks, Matthew DJ;
Poulton, Ian D;
Lawrie, Alison M;
Berrie, Eleanor;
Moyle, Sarah;
Long, Carole A;
Colloca, Stefano;
Cortese, Riccardo;
Gilbert, Sarah C

Publication type:

Article

A Double-modulation Strategy in Cancer Treatment With a Chemotherapeutic Agent and siRNA.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2040, doi. 10.1038/mt.2011.174

By:

Nakamura, Kazuya;
Abu Lila, Amr S;
Matsunaga, Mariko;
Doi, Yusuke;
Ishida, Tatsuhiro;
Kiwada, Hiroshi

Publication type:

Article

Retroviral Gene Therapy for X-linked Chronic Granulomatous Disease: Results From Phase I/II Trial.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2092, doi. 10.1038/mt.2011.166

By:

Kang, Hyoung Jin;
Bartholomae, Cynthia C;
Paruzynski, Anna;
Arens, Anne;
Kim, Sujeong;
Yu, Seung Shin;
Hong, Youngtae;
Joo, Chang-Wan;
Yoon, Nam-Kyung;
Rhim, Jung-Woo;
Kim, Joong Gon;
Von Kalle, Christof;
Schmidt, Manfred;
Kim, Sunyoung;
Ahn, Hyo Seop

Publication type:

Article

AAV Vector Biology in Primates: Finding the Missing Link?

Published in:

2011

By:

Herzog, Roland W;
Davidoff, Andrew M;
Markusic, David M;
Nathwani, Amit C

Publication type:

Editorial

N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1981, doi. 10.1038/mt.2011.160

By:

Suk, Jung Soo;
Boylan, Nicholas J;
Trehan, Kanika;
Tang, Benjamin C;
Schneider, Craig S;
Lin, Jung-Ming G;
Boyle, Michael P;
Zeitlin, Pamela L;
Lai, Samuel K;
Cooper, Mark J;
Hanes, Justin

Publication type:

Article

Intranasal Administration of Adeno-associated Virus Type 12 (AAV12) Leads to Transduction of the Nasal Epithelia and Can Initiate Transgene-specific Immune Response.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1990, doi. 10.1038/mt.2011.146

By:

Quinn, Kathrina;
Quirion, Mary R;
Lo, Chia-Yun;
Misplon, Julia A;
Epstein, Suzanne L;
Chiorini, John A

Publication type:

Article

Hepatorenal Correction in Murine Glycogen Storage Disease Type I With a Double-stranded Adeno-associated Virus Vector.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1961, doi. 10.1038/mt.2011.126

By:

Luo, Xiaoyan;
Hall, Gentzon;
Li, Songtao;
Bird, Andrew;
Lavin, Peter J;
Winn, Michelle P;
Kemper, Alex R;
Brown, Talmage T;
Koeberl, Dwight D

Publication type:

Article

RNA Interference Improves Myopathic Phenotypes in Mice Over-expressing FSHD Region Gene 1 (FRG1).

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2048, doi. 10.1038/mt.2011.118

By:

Wallace, Lindsay M;
Garwick-Coppens, Sara E;
Tupler, Rossella;
Harper, Scott Q

Publication type:

Article

A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2084, doi. 10.1038/mt.2011.108

By:

Monteilhet, Virginie;
Saheb, Samir;
Boutin, Sylvie;
Leborgne, Christian;
Veron, Philippe;
Montus, Marie-Françoise;
Moullier, Philippe;
Benveniste, Olivier;
Masurier, Carole

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2011, v. 19, n. 11, p. 1927, doi. 10.1038/mt.2011.225
Publication type:: Article

Erythropoietin Gene-enhanced Marrow Mesenchymal Stromal Cells Decrease Cisplatin-induced Kidney Injury and Improve Survival of Allogeneic Mice.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2072, doi. 10.1038/mt.2011.162

By:

Eliopoulos, Nicoletta;
Zhao, Jing;
Forner, Kathy;
Birman, Elena;
Young, Yoon Kow;
Bouchentouf, Manaf

Publication type:

Article

AAV6-mediated Systemic shRNA Delivery Reverses Disease in a Mouse Model of Facioscapulohumeral Muscular Dystrophy.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2055, doi. 10.1038/mt.2011.153

By:

Bortolanza, Sergia;
Nonis, Alessandro;
Sanvito, Francesca;
Maciotta, Simona;
Sitia, Giovanni;
Wei, Jessica;
Torrente, Yvan;
Di Serio, Clelia;
Chamberlain, Joel R;
Gabellini, Davide

Publication type:

Article

An Intravenous Stimulus Package for Oncolytic Virotherapy.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1930, doi. 10.1038/mt.2011.217

By:

Vile, Richard;
Melcher, Alan

Publication type:

Article

Capsid-specific T-cell Responses to Natural Infections With Adeno-associated Viruses in Humans Differ From Those of Nonhuman Primates.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2021, doi. 10.1038/mt.2011.81

By:

Li, Hua;
Lasaro, Marcio O;
Jia, Bei;
Lin, Shih Wen;
Haut, Larissa H;
High, Katherine A;
Ertl, Hildegund CJ

Publication type:

Article

Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1950, doi. 10.1038/mt.2011.107

By:

Mattar, Citra NZ;
Nathwani, Amit C;
Waddington, Simon N;
Dighe, Niraja;
Kaeppel, Christine;
Nowrouzi, Ali;
Mcintosh, Jenny;
Johana, Nuryanti B;
Ogden, Bryan;
Fisk, Nicholas M;
Davidoff, Andrew M;
David, Anna;
Peebles, Donald;
Valentine, Marcus B;
Appelt, Jens-Uwe;
von Kalle, Christof;
Schmidt, Manfred;
Biswas, Arijit;
Choolani, Mahesh;
Chan, Jerry KY

Publication type:

Article

Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2031, doi. 10.1038/mt.2011.178

By:

Deichmann, Annette;
Brugman, Martijn H;
Bartholomae, Cynthia C;
Schwarzwaelder, Kerstin;
Verstegen, Monique MA;
Howe, Steven J;
Arens, Anne;
Ott, Marion G;
Hoelzer, Dieter;
Seger, Reinhard;
Grez, Manuel;
Hacein-Bey-Abina, Salima;
Cavazzana-Calvo, Marina;
Fischer, Alain;
Paruzynski, Anna;
Gabriel, Richard;
Glimm, Hanno;
Abel, Ulrich;
Cattoglio, Claudia;
Mavilio, Fulvio

Publication type:

Article

AAV8-mediated Hepatic Gene Transfer in Infant Rhesus Monkeys (Macaca mulatta).

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2012, doi. 10.1038/mt.2011.151

By:

Wang, Lili;
Bell, Peter;
Lin, Jianping;
Calcedo, Roberto;
Tarantal, Alice F;
Wilson, James M

Publication type:

Article

Corrigendum to 'Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs'.

Published in:

2011

By:

Okazuka, Kiyoshi;
Beard, Brian C;
Emery, David W;
Schwarzwaelder, Kerstin;
Spector, Michele R;
Sale, George E;
von Kalle, Christof;
Torok-Storb, Beverly;
Kiem, Hans-Peter;
Blau, C Anthony

Publication type:

Correction Notice

New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1942, doi. 10.1038/mt.2011.182

By:

Vandermeulen, Gaëlle;
Marie, Corinne;
Scherman, Daniel;
Préat, Véronique

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2011, v. 19, n. 11, p. 1926, doi. 10.1038/mt.2011.224
Publication type:: Article

Derivation of Insulin Producing Cells From Human Endometrial Stromal Stem Cells and Use in the Treatment of Murine Diabetes.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2065, doi. 10.1038/mt.2011.173

By:

Santamaria, Xavier;
Massasa, Efi E;
Feng, Yuzhe;
Wolff, Erin;
Taylor, Hugh S

Publication type:

Article

Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1971, doi. 10.1038/mt.2011.157

By:

Bevan, Adam K;
Duque, Sandra;
Foust, Kevin D;
Morales, Pablo R;
Braun, Lyndsey;
Schmelzer, Leah;
Chan, Curtis M;
McCrate, Mary;
Chicoine, Louis G;
Coley, Brian D;
Porensky, Paul N;
Kolb, Stephen J;
Mendell, Jerry R;
Burghes, Arthur HM;
Kaspar, Brian K

Publication type:

Article

A Shift From Cell Cultures to Creatures: In Vivo Imaging of Small Animals in Experimental Regenerative Medicine.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1933, doi. 10.1038/mt.2011.194

By:

Studwell, Anna J;
Kotton, Darrell N

Publication type:

Article

Personalized Cell Transfer Immunotherapy for B-Cell Malignancies and Solid Cancers.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1928, doi. 10.1038/mt.2011.223

By:

Rosenberg, Steven A;
Kochenderfer, James N

Publication type:

Article

Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 1999, doi. 10.1038/mt.2011.119

By:

Nietupski, Jennifer B;
Hurlbut, Gregory D;
Ziegler, Robin J;
Chu, Qiuming;
Hodges, Bradley L;
Ashe, Karen M;
Bree, Mark;
Cheng, Seng H;
Gregory, Richard J;
Marshall, John;
Scheule, Ronald K

Publication type:

Article

Intranasal Exosomes for Treatment of Neuroinflammation?: Prospects and Limitations.

Published in:

2011

By:

Lakhal, Samira;
Wood, Matthew JA

Publication type:

Opinion

Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes.

Published in:

Molecular Therapy, 2011, v. 19, n. 10, p. 1905, doi. 10.1038/mt.2011.135

By:

Hester, Mark E;
Murtha, Matthew J;
Song, SungWon;
Rao, Meghan;
Miranda, Carlos J;
Meyer, Kathrin;
Tian, Jinbin;
Boulting, Gabriella;
Schaffer, David V;
Zhu, Michael X;
Pfaff, Samuel L;
Gage, Fred H;
Kaspar, Brian K

Publication type:

Article

Perturbing PSD-95 Interactions With NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain.

Published in:

Molecular Therapy, 2011, v. 19, n. 10, p. 1780, doi. 10.1038/mt.2011.42

By:

D'Mello, Richard;
Marchand, Fabien;
Pezet, Sophie;
McMahon, Stephen B;
Dickenson, Anthony H

Publication type:

Article