Works matching IS 15250016 AND DT 2010 AND VI 18 AND IP 1

Results: 32

Design and Evaluation of Doxorubicin-containing Microbubbles for Ultrasound-triggered Doxorubicin Delivery: Cytotoxicity and Mechanisms Involved.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 101, doi. 10.1038/mt.2009.160

By:

Lentacker, Ine;
Geers, Bart;
Demeester, Joseph;
De Smedt, Stefaan C.;
Sanders, Niek N.

Publication type:

Article

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 181, doi. 10.1038/mt.2009.207

By:

Takeshita, Fumitaka;
Patrawala, Lubna;
Osaki, Mitsuhiko;
Takahashi, Ryou-u;
Yamamoto, Yusuke;
Kosaka, Nobuyoshi;
Kawamata, Masaki;
Kelnar, Kevin;
Bader, Andreas G.;
Brown, David;
Ochiya, Takahiro

Publication type:

Article

Deficiency of the Housekeeping Gene Hypoxanthine–Guanine Phosphoribosyltransferase (HPRT) Dysregulates Neurogenesis.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 54, doi. 10.1038/mt.2009.178

By:

Guibinga, Ghiabe-Henri;
Hsu, Stephen;
Friedmann, Theodore

Publication type:

Article

Activation of Transgene-specific T Cells Following Lentivirus-mediated Gene Delivery to Mouse Lung.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 143, doi. 10.1038/mt.2009.190

By:

Limberis, Maria P.;
Bell, Christie L.;
Heath, Jack;
Wilson, James M.

Publication type:

Article

Multiple Functions of the 37/67-kd Laminin Receptor Make It a Suitable Target for Novel Cancer Gene Therapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 63, doi. 10.1038/mt.2009.199

By:

Scheiman, Jonathan;
Jen-Chieh Tseng;
Yun Zheng;
Meruelo, Daniel

Publication type:

Article

Image-guided, Intravascular Hydrodynamic Gene Delivery to Skeletal Muscle in Pigs.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 93, doi. 10.1038/mt.2009.206

By:

Kamimura, Kenya;
Guisheng Zhang;
Dexi Liu

Publication type:

Article

Adeno-associated Virus Gene Therapy With Cholesterol 24-Hydroxylase Reduces the Amyloid Pathology Before or After the Onset of Amyloid Plaques in Mouse Models of Alzheimer's Disease.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 44, doi. 10.1038/mt.2009.175

By:

Hudry, Eloise;
Van Dam, Debby;
Kulik, Wim;
De Deyn, Peter P.;
Stet, Femke S.;
Ahouansou, Ornella;
Benraiss, Abdellatif;
Delacourte, André;
Bougnères, Pierre;
Aubourg, Patrick;
Cartier, Nathalie

Publication type:

Article

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 171, doi. 10.1038/mt.2009.208

By:

Abrams, Marc T.;
Koser, Martin L.;
Seitzer, Jessica;
Williams, Stephanie C.;
DiPietro, Martha A.;
Weimin Wang;
Shaw, Andrew W.;
Xianzhi Mao;
Jadhav, Vasant;
Davide, Joseph P.;
Burke, Paul A.;
Sachs, Alan B.;
Stirdivant, Steven M.;
Sepp-Lorenzino, Laura

Publication type:

Article

Suppression of FVIII Inhibitor Formation in Hemophilic Mice by Delivery of Transgene Modified Apoptotic Fibroblasts.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 214, doi. 10.1038/mt.2009.209

By:

Rui-Jun Su;
Epp, Angela;
Latchman, Yvette;
Bolgiano, Doug;
Pipe, Steven W.;
Josephson, Neil C.

Publication type:

Article

G-rich Oligonucleotides Inhibit HIF-1α and HIF-2α and Block Tumor Growth.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 188, doi. 10.1038/mt.2009.219

By:

Guan, Yongli;
Ramasamy Reddy, Kavitha;
Qiqing Zhu;
Yifei Li;
KangAe Lee;
Weerasinghe, Priya;
Prchal, Josef;
Semenza, Gregg L.;
Naijie Jing

Publication type:

Article

Systematic Evaluation of AAV Vectors for Liver directed Gene Transfer in Murine Models.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 118, doi. 10.1038/mt.2009.246

By:

Lili Wang;
Huan Wang;
Bell, Peter;
McCarter, Robert J.;
Jianping He;
Calcedo, Roberto;
Vandenberghe, Luk H.;
Morizono, Hiroki;
Batshaw, Mark L.;
Wilson, James M.

Publication type:

Article

Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 161, doi. 10.1038/mt.2009.222

By:

Beer, Shelly;
Bellovin, David I.;
Lee, Joyce S.;
Komatsubara, Kimberly;
Wang, Lora S.;
Huishan Koh;
Börner, Kathleen;
Storm, Theresa A.;
Davis, Corrine R.;
Kay, Mark A.;
Felsher, Dean W.;
Grimm, Dirk

Publication type:

Article

Polysialic Acid Glycomimetic Promotes Functional Recovery and Plasticity After Spinal Cord Injury in Mice.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 34, doi. 10.1038/mt.2009.235

By:

Mehanna, Ali;
Jakovcevski, Igor;
Acar, Ayşe;
Meifang Xiao;
Loers, Gabriele;
Rougon, Geneviève;
Irintchev, Andrey;
Schachner, Melitta

Publication type:

Article

Adipose Tissue–derived Mesenchymal Stem Cells Expressing Prodrug-converting Enzyme Inhibit Human Prostate Tumor Growth.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 223, doi. 10.1038/mt.2009.237

By:

Cavarretta, Ilaria T.;
Altanerova, Veronika;
Matuskova, Miroslava;
Kucerova, Lucia;
Culig, Zoran;
Altaner, Cestmir

Publication type:

Article

The Pleiotropic Effects of Natural AAV Infections on Liver-directed Gene Transfer in Macaques.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 126, doi. 10.1038/mt.2009.245

By:

Wang, Lili;
Calcedo, Roberto;
Huan Wang;
Bell, Peter;
Grant, Rebecca;
Vandenberghe, Luk H.;
Sanmiguel, Julio;
Morizono, Hiroki;
Batshaw, Mark L.;
Wilson, James M.

Publication type:

Article

The Pharmacological Chaperone 1-Deoxygalactonojirimycin Reduces Tissue Globotriaosylceramide Levels in a Mouse Model of Fabry Disease.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 23, doi. 10.1038/mt.2009.220

By:

Khanna, Richie;
Soska, Rebecca;
Yi Lun;
Feng, Jessie;
Frascella, Michelle;
Young, Brandy;
Brignol, Nastry;
Pellegrino, Lee;
Sitaraman, Sheela A.;
Desnick, Robert J.;
Benjamin, Elfrida R.;
Lockhart, David J.;
Valenzano, Kenneth J.

Publication type:

Article

Long-term Rescue of a Lethal Murine Model of Methylmalonic Acidemia Using Adeno associated Viral Gene Therapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 11, doi. 10.1038/mt.2009.247

By:

Chandler, Randy J.;
Venditti, Charles P.

Publication type:

Article

Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 198, doi. 10.1038/mt.2009.248

By:

Goyenvalle, Aurélie;
Babbs, Arran;
Powell, Dave;
Kole, Ryszard;
Fletcher, Sue;
Wilton, Steve D.;
Davies, Kay E.

Publication type:

Article

AAV8-mediated Gene Therapy Prevents Induced Biochemical Attacks of Acute Intermittent Porphyria and Improves Neuromotor Function.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 17, doi. 10.1038/mt.2009.250

By:

Yasuda, Makiko;
Bishop, David F.;
Fowkes, Mary;
Cheng, Seng H.;
Gan, Lin;
Desnick, Robert J.

Publication type:

Article

Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 151, doi. 10.1038/mt.2009.251

By:

Toromanoff, Alice;
Adjali, Oumeya;
Larcher, Thibaut;
Hill, Marcelo;
Guigand, Lydie;
Chenuaud, Pierre;
Deschamps, Jack-Yves;
Gauthier, Olivier;
Blancho, Gilles;
Vanhove, Bernard;
Rolling, Fabienne;
Chérel, Yan;
Moullier, Philippe;
Anegon, Ignacio;
Le Guiner, Caroline

Publication type:

Article

Dystrophin Delivery to Muscles of mdx Mice Using Lentiviral Vectors Leads to Myogenic Progenitor Targeting and Stable Gene Expression.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 206, doi. 10.1038/mt.2009.253

By:

Kimura, En;
Sheng Li;
Gregorevic, Paul;
Fall, Brent M.;
Chamberlain, Jeffrey S.

Publication type:

Article

Persistent Expression of FLAG-tagged Micro dystrophin in Nonhuman Primates Following Intramuscular and Vascular Delivery.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 109, doi. 10.1038/mt.2009.254

By:

Rodino-Klapac, Louise R.;
Montgomery, Chrystal L.;
Bremer, William G.;
Shontz, Kimberly M.;
Malik, Vinod;
Davis, Nancy;
Sprinkle, Spencer;
Campbell, Katherine J.;
Sahenk, Zarife;
Clark, K. Reed;
Walker, Christopher M.;
Mendell, Jerry R.;
Chicoine, Louis G.

Publication type:

Article

Effect of Genome Size on AAV Vector Packaging.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 80, doi. 10.1038/mt.2009.255

By:

Zhijian Wu;
Hongyan Yang;
Colosi, Peter

Publication type:

Article

Evidence for the Failure of Adeno-associated Virus Serotype 5 to Package a Viral Genome ≥8.2 kb.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 75, doi. 10.1038/mt.2009.256

By:

Yi Lai;
Yongping Yue;
Dongsheng Duan

Publication type:

Article

Proteasome Inhibitors Decrease AAV2 Capsid derived Peptide Epitope Presentation on MHC Class I Following Transduction.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 135, doi. 10.1038/mt.2009.257

By:

Finn, Jonathan D.;
Hui, Daniel;
Downey, Harre D.;
Dunn, Danielle;
Pien, Gary C.;
Mingozzi, Federico;
Shangzhen Zhou;
High, Katherine A.

Publication type:

Article

Characterization of Genome Integrity for Oversized Recombinant AAV Vector.

Published in:

Molecular Therapy, 2010, v. 18, n. 1, p. 87, doi. 10.1038/mt.2009.258

By:

Biao Dong;
Hiroyuki Nakai;
Weidong Xiao

Publication type:

Article

Little Vector, Big Gene Transduction: Fragmented Genome Reassembly of Adeno-associated Virus.

Published in:

2010

By:

Hirsch, Matthew L.;
Agbandje-McKenna, Mavis;
Jude Samulski, R.

Publication type:

Opinion

In the Beginning: Reflections on the Genesis of Molecular Therapy.

Published in:

2010

By:

Wilson, James M.

Publication type:

Opinion

Stem Cell Vaccination Against Cancer: Fighting Fire With Fire?

Published in:

2010

By:

Zwaka, Thomas P.

Publication type:

Opinion

Interesting Times: Molecular Therapy and the Evolving Media of Scientific Publishing.

Published in:

2010

By:

Brenner, Malcolm

Publication type:

Editorial

In This Issue.

Published in:: Molecular Therapy, 2010, v. 18, n. 1, p. 4, doi. 10.1038/mt.2009.289
Publication type:: Article

Research Highlights.

Published in:: Molecular Therapy, 2010, v. 18, n. 1, p. 5, doi. 10.1038/mt.2009.290
Publication type:: Article