Works in Journal of Translational Medicine, 2025, Vol 23, Issue 1

Results: 640

Association of genetically proxied cancer-targeted drugs with cardiovascular diseases through Mendelian randomization analysis.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06027-4

By:

Fang, Chuchun;
Liu, Xuewei;
Yu, Chen;
Li, Songlin;
Liu, Xueying;
Qiu, Shifeng;
Liang, Hongbin;
Ou, Caiwen;
Xiu, Jiancheng

Publication type:

Article

Quality, topics, and demographic trends of animal systematic reviews - an umbrella review.

Published in:

2025

By:

Hild, Bernard Friedrich;
Brüschweiler, David;
Hild, Sophia Theodora Katharina;
Bugajska, Julia;
von Wyl, Viktor;
Rosso, Marianna;
Wever, Kimberley Elaine;
Furrer, Eva;
Ineichen, Benjamin Victor

Publication type:

Literature Review

LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06032-7

By:

Liu, Jun;
Li, Xiang;
Yang, Peng;
He, Yufeng;
Hong, Weilong;
Feng, Yawei;
Ye, Zhiqiang

Publication type:

Article

Metagenomic characterization of oral microbiome signatures to predict upper gastrointestinal and pancreaticobiliary cancers: a case–control study.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05989-9

By:

Oh, Sujin;
Kim, Jaihwan;
Shin, Cheol Min;
Lee, Hyo-Jung;
Lee, Hye Seung;
Park, Kyoung Un

Publication type:

Article

Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05983-1

By:

He, Siyu;
Li, Chunyu;
Lu, Mingxin;
Lin, Fang;
Hu, Sangyu;
Zhang, Junfang;
Peng, Luying;
Li, Li

Publication type:

Article

Unlocking new potential: the evolving landscape of metformin repurposing trials.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06061-2

By:

Zhou, Yating;
Xue, Fei

Publication type:

Article

Crosstalk between ferroptosis and autophagy: broaden horizons of cancer therapy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06059-w

By:

Liu, Xingyu;
Tuerxun, Halahati;
Zhao, Yixin;
Li, Yawen;
Wen, Shuhui;
Li, Xi;
Zhao, Yuguang

Publication type:

Article

Coronary health index based on immunoglobulin light chains to assess coronary heart disease risk with machine learning: a diagnostic trial.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06043-4

By:

Ren, Wenbo;
Zhang, Zichen;
Wang, Yifei;
Wang, Jiangyuan;
Li, Li;
Shi, Lin;
Zhai, Taiyu;
Huang, Jing

Publication type:

Article

Identification of macrophage polarisation and mitochondria-related biomarkers in diabetic retinopathy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06038-1

By:

Liu, Weifeng;
Tong, Bin;
Xiong, Jian;
Zhu, Yanfang;
Lu, Hongwei;
Xu, Haonan;
Yang, Xi;
Wang, Feifei;
Yu, Peng;
Hu, Yunwei

Publication type:

Article

Deep learning-based prediction of HER2 status and trastuzumab treatment efficacy of gastric adenocarcinoma based on morphological features.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-06034-5

By:

Wu, Zhida;
Wang, Tao;
Lan, Junlin;
Wang, Jianchao;
Chen, Gang;
Tong, Tong;
Zhang, Hejun

Publication type:

Article

mRNA vaccines in the context of cancer treatment: from concept to application.

Published in:

2025

By:

Fu, Qiang;
Zhao, Xiaoming;
Hu, Jinxia;
Jiao, Yang;
Yan, Yunfei;
Pan, Xuchen;
Wang, Xin;
Jiao, Fei

Publication type:

Literature Review

Single-cell RNA sequencing highlights the unique tumor microenvironment of small cell neuroendocrine cervical carcinoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05977-z

By:

Wang, Tianyou;
Zhang, Li;
Mei, Song;
Wang, Bo;
Liu, Jiaqi;
Yang, Weiping;
Liao, Jiongbo;
Wang, Chao

Publication type:

Article

Machine learning derivation of two cardiac arrest subphenotypes with distinct responses to treatment.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05975-1

By:

Zhang, Weidong;
Wu, Chenxi;
Ni, Peifeng;
Zhang, Sheng;
Zhang, Hongwei;
Zhu, Ying;
Hu, Wei;
Diao, Mengyuan

Publication type:

Article

Systematic comparison of quantity and quality of RNA recovered with commercial FFPE tissue extraction kits.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05890-5

By:

Dube, Sukoluhle;
Al-Mannai, Sharefa;
Liu, Li;
Tomei, Sara;
Hubrack, Satanay;
Sherif, Shimaa;
Jabeen, Ayesha;
Ahmed, Eiman I.;
Sanchez, Apryl;
Mifsud, William;
Bedognetti, Davide;
Hendrickx, Wouter;
Raynaud, Christophe M.

Publication type:

Article

Editorial Expression of Concern: Abroma Augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via Inhibition of oxidative stress and inflammatory response.

Published in:

2025

By:

Khanra, Ritu;
Dewanjee, Saikat;
Dua, Tarun K;
Sahu, Ranabir;
Gangopadhyay, Moumita;
De Feo, Vincenzo;
Zia-Ul-Haq, Muhammad

Publication type:

Editorial

The differential expression of MAGI2 in glomerulopathies and its application as a molecular discriminator of podocytopathies.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06696-9

By:

Siegerist, Florian;
Hay, Eleonora;
Hammer, Elke;
Iervolino, Anna;
Weber, Claudia;
Dikou, Juan Saydou;
Stamellou, Eleni;
Butt, Linus;
Benzing, Thomas;
Wiech, Thorsten;
Brinkötter, Paul T.;
Zimmerman, Uwe;
Capasso, Giovambattista;
Chatziantoniou, Christos;
Chadjichristos, Christos E.;
Huber, Tobias B.;
Völker, Uwe;
Schindler, Maximilian;
Endlich, Nicole

Publication type:

Article

A call to reignite the revolutionary spirit of scientific discovery.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06669-y

By:

Asadi, Ali;
Marincola, Francesco M.

Publication type:

Article

Paracrine signaling in cancer-associated fibroblasts: central regulators of the tumor immune microenvironment.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06744-4

By:

Li, Ye;
Wang, Longyun;
Ma, Wenzhe;
Wu, Jibiao;
Wu, Qibiao;
Sun, Changgang

Publication type:

Article

Danshenol B alleviates central post-stroke pain by regulating the PIK3CG/NLRP3 signaling pathway.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06719-5

By:

Li, Panyang;
Yu, Linna;
Yao, Jinzhong;
Zhao, Tingting;
Zhao, Sen

Publication type:

Article

A pyrimidine metabolism-related gene signature for prognosis prediction and immune microenvironment description of breast cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06700-2

By:

Wang, Han;
Zhou, Ziling;
Zhong, Hanyi;
Wang, Shoutang;
Shen, Kunwei;
Huang, Renhong;
Wang, Ruo;
Wang, Zheng

Publication type:

Article

Notch3 enhances the synergistic effect of all-trans retinoic acid and calcipotriol in pancreatic stellate cell activation.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06666-1

By:

Lian, Zheng;
Du, Wei-hong;
Tusup-han, Paizi-guli;
Zhang, Yu-xiang

Publication type:

Article

The G-quadruplex ligand CX-5461: an innovative candidate for disease treatment.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06473-8

By:

Li, Hong-Xia;
He, Yi-Meng;
Fei, Jing;
Guo, Man;
Zeng, Chen;
Yan, Pi-Jun;
Xu, Yong;
Qin, Gang;
Teng, Fang-Yuan

Publication type:

Article

Identifying pathways to cardiovascular mortality by causal graphical models and mediation analysis among hypertensive patients: insights from a prospective study.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06755-1

By:

Tian, Simiao;
Li, Zhen;
Bi, Yanhong;
Che, Xiaoyu;
Feng, Ao;
Wang, Yiou

Publication type:

Article

OncoE25: an AI model for predicting postoperative prognosis in early-onset stage I-III colon and rectal cancer—a population-based study using SEER with dual-center cohort validation.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06663-4

By:

Yuan, Luyun;
Wang, Liyu;
Gao, Jiamin;
Chen, Xin;
Wang, Haoyue;
Tan, Wei Shan;
Sun, Kexiang;
Gong, Yabin;
Deng, Wanli

Publication type:

Article

Heterogeneous tissue-specific macrophages orchestrate metastatic organotropism of breast cancer: implications for promising therapeutics.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06660-7

By:

Wang, Cenzhu;
Fan, Pinchao;
Zhou, Yu;
Ma, Meican;
Zhong, Haowei;
Liu, Lei;
Chen, Qin;
Xu, Kun

Publication type:

Article

Integrated peripheral blood multi-omics profiling identifies immune signatures predictive of neoadjuvant PD-1 blockade efficacy in head and neck squamous cell carcinoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06770-2

By:

Zhang, Hao;
Wu, Wenjie;
Wang, Meng;
Zhang, Jie;
Guo, Chuanbin;
Han, Guojun;
Wang, Lin

Publication type:

Article

Overexpression of oncogenic polo-like kinase 1 disrupts the invasiveness, cell cycle, and apoptosis in synovial sarcoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06740-8

By:

Zhang, Jun;
Li, Zhong;
Xie, Ming-Yu;
Wang, Ning;
Liu, Hao;
Li, Feng;
Pang, Li-Juan;
Qi, Yan

Publication type:

Article

Development of a prognostic immune cell-based model for ovarian cancer using multiplex immunofluorescence.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06745-3

By:

Li, Sai;
Jiang, Boyang;
Zhou, Hongying;
Yang, Sifu;
Yang, Liu;
Hong, Yupeng

Publication type:

Article

Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06732-8

By:

Zhang, Dechun;
Pei, Shaoxuan;
Feng, Zixuan;
Xia, Guangfeng

Publication type:

Article

Transitioning a multiethnic donor pool from serologic D-negative to molecularly RHD-negative at a hospital-based blood donor service.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06716-8

By:

Flegel, Willy A.;
Srivastava, Kshitij;
Caruccio, Lorraine G.;
Schmid, Pirmin;
Stiles, David A.;
Bueno, Marina U.;
Dowling, Nadine R.;
Paige, Traci D.;
Shrestha, Sita

Publication type:

Article

Acute effects of a single bout of high-intensity strength and endurance exercise on cognitive biomarkers in young adults and elderly men: a within-subjects crossover study.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06685-y

By:

Bekkos, Carolin Haberstroh;
Sujan, Md Abu Jafar;
Stunes, Astrid Kamilla;
Tari, Atefe Rafiee;
Aagård, Norun;
Brobakken, Cathrine Langlie;
Brevig, Martin Siksjø;
Syversen, Unni;
Wang, Eivind;
Mosti, Mats Peder

Publication type:

Article

p53 in colorectal cancer: from a master player to a privileged therapy target.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06566-4

By:

Yan, Sicheng;
Zhan, Fuyuan;
He, Yuxuan;
Zhu, Yuehong;
Ma, Zhihong

Publication type:

Article

Experimental animal models and patient-derived platforms to bridge preclinical discovery and translational therapeutics in pulmonary arterial hypertension.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06709-7

By:

Singh, Elizabeth;
Bisserier, Malik

Publication type:

Article

Long-term investigation of 3D tissue detailed structure and multiparametric vascular network properties using OCT/OCTA for guiding atopic dermatitis theranostics.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06228-5

By:

Du, Fengxian;
Wu, Huiling;
Xue, Junwei;
Yao, Shenglan;
Li, Ronghui;
Zhang, Jinde;
Wang, Haitao;
Cheng, Qi;
Zhao, Fan;
Huang, Ying;
Zhou, Zijian;
Liang, Feng;
Gu, Xiufei;
Tuchin, Valery V.;
Zhao, Qingliang

Publication type:

Article

Decoding hippocampal subfield and glial responses in ischemia using single-cell transcriptomics.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06738-2

By:

Kwak, Donghee;
Park, Ji Hyun;
Kim, Yun Hak;
Yoo, Hong Il

Publication type:

Article

Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC).

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06730-w

By:

Scordamaglia, Domenica;
Talia, Marianna;
Cirillo, Francesca;
Zicarelli, Azzurra;
Mondino, Adelina Assunta;
De Rosis, Salvatore;
Di Dio, Marika;
Silvestri, Francesca;
Meliti, Chiara;
Miglietta, Anna Maria;
Capalbo, Carlo;
De Francesco, Ernestina Marianna;
Belfiore, Antonino;
Maggiolini, Marcello;
Lappano, Rosamaria

Publication type:

Article

Innovative approaches to CAR-T cell therapy: the role of lipid metabolism pathways.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06718-6

By:

Guo, Minjie;
Zhang, Yuting;
Yuan, Xiao;
Wang, Xu

Publication type:

Article

A comment on "Association between oral microbiome diversity and chronic obstructive pulmonary disease in the US population".

Published in:

2025

By:

Luo, Mingwu;
Xin, Kai;
Luo, Tao

Publication type:

Letter to the Editor

Precise prediction of bone metastases and metastatic burden using exosomal mirnas and radiomics: a multi-center study.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06691-0

By:

Wang, Chao;
Wei, Xu-Pan;
Zhou, Chuan;
Wang, Jia;
Zhang, Yun-Feng;
He, Han;
Zhang, Wen-Bo;
Lv, Hao-Xuan;
Wang, Fang;
Zhou, Feng-Hai

Publication type:

Article

The roles of Cryptochrome-1: the circadian clock as a control point in cancer therapy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06702-0

By:

Liu, Yijia;
Huang, Yanzhe;
Luo, Hongliang;
Lin, Xueqin

Publication type:

Article

Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06701-1

By:

Gao, Lin;
Liao, Hua;
Chen, Yuehua;
Ye, Cuiping;
Huang, Liping;
Xu, Mingming;
Du, Jiangzhou;
Zhang, Jinming;
Huang, Danhui;
Cai, Shaoxi;
Dong, Hangming

Publication type:

Article

Targeting Drp1 inhibits ESCC progression via the ROS-PGC1-α-Nrf1/2 pathway.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06697-8

By:

Jiang, Zhixiong;
Yang, Yating;
Zhou, Jinchi;
Li, Xin;
Meng, Qingqing;
Yu, Xiangyi;
Xue, Yaxin;
Li, Mengyu;
Cai, Yichen;
Han, Pengchun;
Jiang, Mingjun;
Wang, Huizhen;
Liu, Congrong;
Zhao, Jing;
Wan, Lixin;
Bao, Dengke

Publication type:

Article

Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06682-1

By:

Wang, Zhan;
Zhou, Zhaokai;
Yang, Shuai;
Li, Zhengrui;
Shi, Run;
Wang, Ruizhi;
Liu, Kui;
Tang, Xiaojuan;
Li, Qi

Publication type:

Article

The hidden causes of pregnancy loss: a closer look.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06678-x

By:

Shi, Panlai;
Wang, Conghui;
Liang, Hongbin;
Zhu, XiaoFan;
Wang, Xinyan;
Ning, Yanting;
Leigh, Don;
Cram, David S.;
Kong, Xiangdong

Publication type:

Article

Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06699-6

By:

Petroková, Hana;
Mierzwicka, Joanna Maria;
Chakraborty, Prosenjit;
Rašková Kafková, Leona;
Vaculová, Jana;
Škarda, Jozef;
Fischer, Ondřej;
Kosztyu, Petr;
Kuchař, Milan;
Raška, Milan;
Malý, Petr

Publication type:

Article

Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06680-3

By:

Li, Xin;
Zhang, Juxuan;
Zhang, Meng;
Jiang, Wenbin;
Jia, Dexin;
Wang, Ruxiong;
Li, Hao;
Wang, Zhihui;
Liu, Yixin;
Tang, Lefan;
Deng, Jiaxing;
Zhao, Wenyuan;
Yu, Yan;
Liu, Shilong;
Qi, Lishuang

Publication type:

Article

The pasteurized Weissella cibaria alleviates sepsis-induced acute lung injury by modulation of intestinal mucus barrier and gut microbiota.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06674-1

By:

Li, Yuanzhe;
Yang, Debin;
Zhao, Huan;
Dou, Liping;
Chen, Qian;
Cheng, Yibing;
Hu, Bo;
Tang, Yu;
Duan, Yongtao;
Guo, Caili;
Sakandar, Abbas;
Li, Dong

Publication type:

Article

Cross-cohort analysis identifies shared gut microbial signatures and validates microbial risk scores for colorectal cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06676-z

By:

Zhang, Yuhan;
Luo, Jiahui;
Chen, Kuangyu;
Li, Na;
Luo, Chenyu;
Di, Shuang;
Qin, Junjie;
Zhang, Feng;
Chen, Hongda;
Dai, Min

Publication type:

Article

Raman micro-spectroscopy reveals the metabolic alterations in primary prostate tumor tissues of patients with metastases.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06655-4

By:

Shao, Xiaoguang;
Liu, Bo;
Qian, Hongyang;
Zhang, Qihan;
Zhu, Yinjie;
Liu, Shupeng;
Zhang, Heng;
Pan, Jiahua;
Xue, Wei

Publication type:

Article

Proteomic and metabolomic analysis of platelet related samples reveals energy metabolism disorders in hepatocellular carcinoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06694-x

By:

Ruan, Xuelian;
Hu, Zuojian;
Shen, Fenglin;
Chen, Yongling;
Zhong, Ziqing;
Ou, Guiyong;
Luo, Xing;
Qin, Xue;
Wang, Huabing

Publication type:

Article