Works matching IS 14769255 AND DT 2013 AND VI 10 AND IP Suppl 1

Results: 42

Considerations for therapeutic intervention models of pulmonary fibrosis.

Published in:

2013

By:

Wilder, J. A.;
Doyle-Eisele, M.;
Gott, K. M.;
Shi, Y.;
Guilmette, R.;
Gigliotti, A.;
McDonald, J.;
Rosas, I. O.

Publication type:

Abstract

Therapeutic efficacy of Sunitinib and other broad spectrum receptor tyrosine kinase inhibitors (RTKI) in bleomycin-induced pulmonary fibrosis.

Published in:

2013

By:

Knoerzer, D.;
Baginski, T.;
Wade, K.;
Fan, C.;
Rapp, S.;
Regina, K.;
Shih, F.;
Burney, M.;
Rouw, S.;
Welsch, D.

Publication type:

Abstract

Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling.

Published in:

2013

By:

Kojonazarov, Baktybek;
Sydykov, Akylbek;
Savai Pullamsetti, Soni;
Luitel, Himal;
Dahal, Bhola K.;
Kosanovic, Djuro;
Xia Tian;
Majewski, Matthaeus;
Baumann, Christin;
Evans, Steve;
Phillips, Peter;
Fairman, David;
Davie, Neil;
Wayman, Chris;
Kilty, Iain;
Weissmann, Norbert;
Grimminger, Friedrich;
Seeger, Werner;
Ardeschir Ghofrani, Hossein;
Theo Schermuly, Ralph

Publication type:

Abstract

Dry powder inhaled compound delivery for early pre-clinical in vivo efficacy studies.

Published in:

2013

By:

Ives, Robert;
Butterfield, Lindsay;
Farr, John;
Bater, Shaun;
Nials, Tony;
Entwistle, Lewis;
Ball, Doug;
Hessel, Edith

Publication type:

Abstract

Strategies to improve lung absorption of intratracheally administered compounds in Drug Discovery.

Published in:

2013

By:

Calama, Elena;
Vives, Montserrat;
Ramis, Isabel;
Espinosa, Sonia;
Pérez, Juan;
Huerta, Josep Maria;
De Alba, Jorge;
Eichhorn, Peter

Publication type:

Abstract

Brown Norway ovalbumin model: temporal profile of cytokines.

Published in:

Journal of Inflammation, 2013, v. 10, n. Suppl 1, p. 1, doi. 10.1186/1476-9255-10-S1-P9

By:

Woodhouse, Janice D.;
Wilhelm, Alan;
Caniga, Michael;
Gil, Malgorzata;
Jie Zhang-Hoover;
McLeod, Robbie;
Moy, Lily Y.;
Cicmil, Milenko

Publication type:

Article

Alterations in airway mechanics, inflammatory biomarkers and lung histopathology in a rat model of allergen-induced airway inflammation.

Published in:

Journal of Inflammation, 2013, v. 10, n. Suppl 1, p. 1, doi. 10.1186/1476-9255-10-S1-P8

By:

Jordan, Stephen M.;
Armstrong, Rachel A.;
Hincks, Jennifer;
Bell, David;
Meecham, Kenneth G.

Publication type:

Article

Immunological characterisation of an acute murine model of lung inflammation and airway hyperreactivity.

Published in:

2013

By:

Dixon, Kate L.;
Yee-Man Ching;
Coote, Julie;
Gozzard, Neil

Publication type:

Abstract

Characterisation of the allergic phenotype resulting from a shortened HDM challenge protocol in mice.

Published in:

2013

By:

Uddin, Sorif;
Morley, Joanne;
Hughes, Sara;
Hessel, Edith

Publication type:

Abstract

Acidic mammalian chitinase is not a critical target for allergic airway disease in mice.

Published in:

2013

By:

Fitz, L. J.;
DeClercq, C.;
Brooks, J.;
Kuang, W.;
Bates, B.;
Demers, D.;
Winkler, A.;
Nocka, K.;
Jiao, A.;
Greco, R. M.;
Mason, L. E.;
Fleming, M.;
Quazi, A.;
Wright, J.;
Goldman, S.;
Hubeau, C.;
Williams, C. M.

Publication type:

Abstract

Viral exacerbation of chronic airway inflammation in BALB/c mice sensitized with house dust mite (HDM): a role for corticosteroids?

Published in:

2013

By:

Barrett, Edward G.;
Senft, Al P.;
Nicodem, Jennifer;
Armes, Dylan;
Gaskins, Aaron;
Giannini, Ginevra

Publication type:

Abstract

Do allergic dogs exhibit features of a severe steroid-resistant allergic airway phenotype?

Published in:

2013

By:

Barrett, Edward G.;
Royer, Christopher M.;
Rudolph, Karin;
Kuehl, Phillip J.

Publication type:

Abstract

Longitudinal characterisation of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods.

Published in:

2013

By:

Changani, Kumar;
Pereira, Catherine;
Young, Simon;
Shaw, Robert;
Campbell, Simon P.;
Pindoria, Kashmira;
Jordan, Steve;
Wiley, Katherine;
Bolton, Sarah;
Nials, Tony;
Haase, Michael;
Pedrick, Mike;
Knowles, Richard

Publication type:

Abstract

A COPD-like model of viral exacerbation: synergistic effects with smoke and poly I:C.

Published in:

2013

By:

Schlerman, F.;
Kubera, J.;
Fleming, M.;
Nocka, K.;
Williams, C.

Publication type:

Abstract

Interleukin-6 neutralization alleviates acute exacerbation-like disease in a model of cigarette smoke-induced pulmonary inflammation.

Published in:

2013

By:

Kubera, John;
Hammerman, Katherine;
Williams, Cara M. M.;
Hubeau, Cedric

Publication type:

Abstract

A translational approach to test anti-inflammatory drugs in a LPS induced acute lung inflammation model in the common marmoset (Callithrix jacchus).

Published in:

2013

By:

Seehase, S.;
Switalla, S.;
Neuhaus, V.;
Zöller, M.;
Kaup, F. J.;
Schlumbohm, C.;
Fuchs, E.;
Lauenstein, H. D.;
Sewald, K.;
Hohlfeld, J. M.;
Braun, A.;
Knauf, S.

Publication type:

Abstract

Steroid-insensitive tobacco smoke-induced lung inflammation models in the mouse.

Published in:

2013

By:

Russell, V.;
Spicer, D.;
Woodman, P.;
Connolly, A.;
Young, A.

Publication type:

Abstract

Steroid insensitive respiratory inflammation - an acute tobacco smoke model.

Published in:

2013

By:

Ramaprakash, Hemanth;
Riley, Jason;
Rao, Navin L.

Publication type:

Abstract

Modulation of IL-17A and TL1A largely abrogates house dust mite-induced lung inflammation in murine model of allergic airway disease.

Published in:

2013

By:

Hubeau, C.;
Kubera, J.;
Hammerman, K.;
Wright J, J.;
Denz, M.;
Juang, Y-T.;
Williams, C.

Publication type:

Abstract

Lipopolysaccharide (LPS) segmental lung challenge in nonhuman primates – a model of airway inflammation.

Published in:

2013

By:

Schlerman, Franklin J.;
Bree, Andrea G.;
Wadanoli, Michael D.;
Goldman, Samuel J.;
Williams, Cara M. M.;
Sypek, Joseph P.

Publication type:

Abstract

A mouse model of acute exacerbations of lung inflammation in COPD with both steroid-sensitive and steroid-insensitive features.

Published in:

2013

By:

Russell, V.;
Connolly, A.;
Jagger, C.;
Spicer, D.;
Woodman, P.;
Dlugozima, J.;
Young, A.

Publication type:

Abstract

Impaired anti-viral immune response to human rhinovirus 1B infection in chronic allergic airway inflammation does not manifest in asthma exacerbation.

Published in:

2013

By:

Rochlitzer, Sabine;
Hoymann, Heinz-Gerd;
Braun, Armin;
Müller, Meike

Publication type:

Abstract

Models of respiratory disease symposium.

Published in:

2013

By:

Abbott-Banner, Kathy H.;
Holmes, Anthony;
Adcock, Ian;
Rao, Navin L.;
Barrett, Edward;
Knowles, Richard

Publication type:

Conference Paper/Materials

Relative sensitivity of mice to inhaled ozone and cigarette smoke exposure.

Published in:

2013

By:

Armstrong, Rachel A.;
Jordan, Stephen M.;
McConnell, Emma;
Carrington, Robert;
Rodgers, Debbie;
Meecham, Kenneth G.

Publication type:

Abstract

Characterization of MMP-9 and -12 KO mice in a model of acute smoke exposure.

Published in:

2013

By:

Schlerman, Franklin J.;
Kubera, John E.;
Pazdziorko, Stephen P.;
Bowman, Michael R.;
Jacobson, Bruce A.;
Fleming, Margaret;
Williams, Cara M. M.;
Sypek, Joseph P.

Publication type:

Abstract

Influenza exacerbations in an acute and chronic house dust mite 'asthma' model.

Published in:

2013

By:

Bal, Suzanne M.;
Ravanetti, Lara;
Dijkhuis, Annemiek;
Lutter, Rene

Publication type:

Abstract

Mouse model of HDM induced airway inflammation + influenza or RSV. Effects of steroid.

Published in:

2013

By:

Lamb, Dave;
Muir, Christina;
Chappell, Debbie;
Mori, Hiroki;
Parker, Nicole;
Hulland, Katy;
Westbrook, Dominique;
Burki, Umar;
Hincks, Jenny;
White, Tony;
Spampinato, Vittorio;
Bright, Helen;
Evans, Steve

Publication type:

Abstract

Preclinical animal models of COPD.

Published in:

2013

By:

Vlahos, Ross

Publication type:

Abstract

Antiviral effect of eosinophils in respiratory tract infection with influenza virus in mice.

Published in:

2013

By:

Bal, Suzanne M.;
Dijkhuis, Annemiek;
van der Sluijs, Koen;
Lutter, Rene

Publication type:

Abstract

Poly I:C causes exacerbation in a murine allergic inflammation model driven by house dust mite in Freund's complete adjuvant.

Published in:

2013

By:

De Alba, Jorge;
Otal, Raquel;
Calama, Elena;
Félix Gil;
Gozzard, Neil;
Miralpeix, Montserrat

Publication type:

Abstract

Assessment of the time course of chronic inflammation in the murine house dust mite model.

Published in:

2013

By:

Jordan, Stephen M.;
Carrington, Robert;
Lanham, David;
Cartwright, James;
Armstrong, Rachel A.;
Meecham, Kenneth G.

Publication type:

Abstract

In-depth assessment of acute and chronic house dust mite-induced asthma mouse models.

Published in:

2013

By:

Bunting, Rachel A.;
Wertheimer, Josh;
Zhao Zhou;
Cochlin, Karyn;
Deutsch, Heather;
Raymond, Holly;
Yurkow, Ed;
Ogden, Carol Anne;
Kilgore, Ken

Publication type:

Abstract

Strategies to mimic virally induced asthmatic exacerbations: the use of rhinovirus and influenza in acute and chronic mouse models.

Published in:

2013

By:

Shaw, R. J.;
Sowa, M.;
Pedrick, M. S.;
Fife, M.;
Nials, A. T.;
Knowles, R. G.;
Hessel, E.

Publication type:

Abstract

Mast cell mediators cause the early allergic bronchoconstriction in guinea pigs in vivo: a model of relevance to asthma.

Published in:

2013

By:

Riley, Jason P.;
Fuchs, Barbara;
Sjöberg, Lisa;
Nilsson, Gunnar P.;
Karlsson, Lars;
Dahlén, Sven-Erik;
Rao, Navin L.;
Adner, Mikael

Publication type:

Abstract

Plasmacytoid dendritic cells downregulate the allergen induced T cell proliferation in a human in vitro allergy modelz.

Published in:

2013

By:

Schaumann, Frank;
Braun, Armin;
Müller, Meike

Publication type:

Abstract

Development of a model of Ascaris Suum antigen-induced pulmonary inflammation in nonhuman primates.

Published in:

2013

By:

Bree, Andrea G.;
Schlerman, Franklin J.;
Wadanoli, Michael D.;
I-Ming Wang;
Goldman, Samuel J.;
Sypek, Joseph P.

Publication type:

Abstract

Assessment of multiple pharmacological mechanisms in the ascaris sensitive sheep model of allergic asthma.

Published in:

2013

By:

Caniga, Michael;
Woodhouse, Janice D.;
Wilhelm, Alan;
Gil, Malgorzata A.;
McLeod, Robbie;
Moy, Lily Y.;
Crackower, Michael A.;
Miller, Thomas;
Abraham, William M.;
Cicmil, Milenko

Publication type:

Abstract

A novel TLR-8 agonist attenuates nasal symptoms/congestion in both dog and human allergen challenge studies.

Published in:

2013

By:

Barrett, Edward G.;
Rudolph, Karin;
Matthews, Maura;
Dietsch, Greg;
Hershberg, Robert

Publication type:

Abstract

Effect of the circadian cycle in Late Asthmatic Response (LAR). Comparison between two allergic asthma models in rats and mice.

Published in:

2013

By:

Otal, Raquel;
Muñoz, Sandra;
Calama, Elena;
Pagán, Isabel;
Gil, Félix;
Torán, Núria;
Miralpeix, Montserrat;
De Alba, Jorge

Publication type:

Abstract

Time-course of inflammation and allergic bronchoconstrictor response in a model of ovalbumin-induced rapid pulmonary inflammation in Brown Norway rats.

Published in:

2013

By:

Uddin, Sorif;
Hughes, Sara;
Hessel, Edith

Publication type:

Abstract

Exploring the role of SYK in respiratory in vivo models.

Published in:

2013

By:

Caniga, Michael;
Woodhouse, Janice D.;
Wilhelm, Alan;
Gil, Malgorzata A.;
Yanlin Jia;
Hongshi Yu;
Vincent, Stella;
Miller, Richard;
Lieber, Gissela;
Fernandez, Xiomara;
Chapman, Richard;
McLeod, Robbie;
Moy, Lily Y.;
Kelly, Nancy;
Hickey, Emily;
Crackower, Michael A.;
Miller, Thomas;
Abraham, William M.;
Cicmil, Milenko

Publication type:

Abstract

Alternaria alternata induced inflammatory lung responses: a novel in vivo PK/PD model.

Published in:

2013

By:

Gil, Malgorzata;
Caniga, Michael;
Eckman, Joseph;
McLeod, Robbie;
Moy, Lily;
Wilhelm, Alan;
Woodhouse, Janice;
Jie Zhang-Hoover;
Cicmil, Milenko

Publication type:

Abstract