Works in Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, Vol 36, Issue 1

Results: 185

Design, synthesis, and biological evaluation of novel triazoloquinazolinone derivatives as SHP2 protein inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2170, doi. 10.1080/14756366.2021.1986491

By:

Luo, Rongshuang;
Wang, Zhongyuan;
Luo, Dali;
Qin, Yumei;
Zhao, Chunshen;
Yang, Di;
Lu, Tian;
Zhou, Zhixu;
Huang, Zhuyan

Publication type:

Article

Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2183, doi. 10.1080/14756366.2021.1984904

By:

Abd El-Hameed, Rania Helmy;
Sayed, Amira Ibrahim;
Mahmoud Ali, Shima;
Mosa, Mohamed A.;
Khoder, Zainab M.;
Fatahala, Samar Said

Publication type:

Article

Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2139, doi. 10.1080/14756366.2021.1984903

By:

Bian, Ming;
Ma, Qian-qian;
Wu, Yun;
Du, Huan-huan;
Guo-hua, Gong

Publication type:

Article

Development of a fluorogenic ADAMTS-7 substrate.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2160, doi. 10.1080/14756366.2021.1983808

By:

Santamaria, Salvatore;
Buemi, Frederic;
Nuti, Elisa;
Cuffaro, Doretta;
De Vita, Elena;
Tuccinardi, Tiziano;
Rossello, Armando;
Howell, Steven;
Mehmood, Shahid;
Snijders, Ambrosius P.;
de Groot, Rens

Publication type:

Article

Recent advance in the discovery of tyrosinase inhibitors from natural sources via separation methods.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2104, doi. 10.1080/14756366.2021.1983559

By:

Zhang, Xiao-wei;
Bian, Guang-li;
Kang, Pei-ying;
Cheng, Xin-jie;
Yan, Kai;
Liu, Yong-li;
Gao, Yan-xia;
Li, De-qiang

Publication type:

Article

Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors?

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2118, doi. 10.1080/14756366.2021.1982933

By:

Riafrecha, Leonardo E.;
Le Pors, Macarena S.;
Lavecchia, Martín J.;
Bua, Silvia;
Supuran, Claudiu T.;
Colinas, Pedro A.

Publication type:

Article

Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2128, doi. 10.1080/14756366.2021.1982932

By:

Fiorentino, Francesco;
De Angelis, Marta;
Menna, Martina;
Rovere, Annarita;
Caccuri, Anna Maria;
D'Acunzo, Francesca;
Palamara, Anna Teresa;
Nencioni, Lucia;
Rotili, Dante;
Mai, Antonello

Publication type:

Article

Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2080, doi. 10.1080/14756366.2021.1981306

By:

Linciano, Pasquale;
Pinzi, Luca;
Belluti, Silvia;
Chianese, Ugo;
Benedetti, Rosaria;
Moi, Davide;
Altucci, Lucia;
Franchini, Silvia;
Imbriano, Carol;
Sorbi, Claudia;
Rastelli, Giulio

Publication type:

Article

Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2045, doi. 10.1080/14756366.2021.1978081

By:

Jiang, Xiaoying;
Guo, Jianan;
Zhang, Changjun;
Gu, Jinping;
Zhou, Tao;
Bai, Renren;
Xie, Yuanyuan

Publication type:

Article

A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2087, doi. 10.1080/14756366.2021.1977931

By:

Zhang, Zhe;
Zhang, Zhao-Sheng;
Wang, Xiao;
Xi, Gao-Lei;
Jin, Zhen;
Tang, You-Zhi

Publication type:

Article

High-yield synthesis and purification of recombinant human GABA transaminase for high-throughput screening assays.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2016, doi. 10.1080/14756366.2021.1975697

By:

Park, Mingu Gordon;
Han, Ah-reum;
Kim, Su Yeon;
Kim, Tai Young;
Kim, Ho Min;
Lee, C. Justin

Publication type:

Article

Discovery of facile amides-functionalized rhodanine-3-acetic acid derivatives as potential anticancer agents by disrupting microtubule dynamics.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1996, doi. 10.1080/14756366.2021.1975695

By:

Zhou, Xiang;
Liu, Jiamin;
Meng, Jiao;
Fu, Yihong;
Wu, Zhibin;
Ouyang, Guiping;
Wang, Zhenchao

Publication type:

Article

Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2068, doi. 10.1080/14756366.2021.1975694

By:

Iacono, Roberta;
Minopoli, Nadia;
Ferrara, Maria Carmina;
Tarallo, Antonietta;
Damiano, Carla;
Porto, Caterina;
Strollo, Sandra;
Roig-Zamboni, Véronique;
Peluso, Gianfranco;
Sulzenbacher, Gerlind;
Cobucci-Ponzano, Beatrice;
Parenti, Giancarlo;
Moracci, Marco

Publication type:

Article

New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure–activity relationships, and molecular modelling.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2025, doi. 10.1080/14756366.2021.1975277

By:

Vicente-Blázquez, Alba;
González, Myriam;
Medarde, Manuel;
Mollinedo, Faustino;
Peláez, Rafael

Publication type:

Article

An overview on the recently discovered iota-carbonic anhydrases.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1988, doi. 10.1080/14756366.2021.1972995

By:

Nocentini, Alessio;
Supuran, Claudiu T.;
Capasso, Clemente

Publication type:

Article

The possible role of methylglyoxal metabolism in cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2010, doi. 10.1080/14756366.2021.1972994

By:

Alfarouk, Khalid O.;
Alqahtani, Saad S.;
Alshahrani, Saeed;
Morgenstern, Jakob;
Supuran, Claudiu T.;
Reshkin, Stephan J.

Publication type:

Article

1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1968, doi. 10.1080/14756366.2021.1972993

By:

Safrygin, Alexander;
Zhmurov, Petr;
Dar'in, Dmitry;
Silonov, Sergey;
Kasatkina, Mariia;
Zonis, Yulia;
Gureev, Maxim;
Krasavin, Mikhail

Publication type:

Article

Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2055, doi. 10.1080/14756366.2021.1972992

By:

Mirgany, Tebyan O.;
Abdalla, Ashraf N.;
Arifuzzaman, Md;
Motiur Rahman, A. F. M.;
Al-Salem, Huda S.

Publication type:

Article

In vitro and in silico studies of bis (indol-3-yl) methane derivatives as potential α-glucosidase and α-amylase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1938, doi. 10.1080/14756366.2021.1971976

By:

Zheng, Peng-Fei;
Xiong, Zhuang;
Liao, Cui-ying;
Zhang, Xin;
Feng, Mei;
Wu, Xiao-Zheng;
Lin, Jing;
Lei, Lin-Sheng;
Zhang, You-Cheng;
Wang, Shao-Hua;
Xu, Xue-Tao

Publication type:

Article

Correction.

Published in:: 2021
Publication type:: Correction Notice

Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1916, doi. 10.1080/14756366.2021.1969386

By:

Safrygin, Alexander;
Zhmurov, Petr;
Dar'in, Dmitry;
Silonov, Sergey;
Kasatkina, Mariia;
Zonis, Yulia;
Gureev, Maxim;
Krasavin, Mikhail

Publication type:

Article

Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1922, doi. 10.1080/14756366.2021.1969385

By:

Hassan, Ahmed H. E.;
Phan, Trong-Nhat;
Yoon, Seolmin;
Lee, Cheol Jung;
Jeon, Hye Rim;
Kim, Seung-Hwan;
No, Joo Hwan;
Lee, Yong Sup

Publication type:

Article

Microwave-assisted Phospha-Michael addition reactions in the 13α-oestrone series and in vitro antiproliferative properties.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1931, doi. 10.1080/14756366.2021.1963241

By:

Mernyák, Erzsébet;
Bartha, Sándor;
Kóczán, Lili;
Jójárt, Rebeka;
Resch, Vivien;
Paragi, Gábor;
Vágvölgyi, Máté;
Hunyadi, Attila;
Bruszel, Bella;
Zupkó, István;
Minorics, Renáta

Publication type:

Article

Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1905, doi. 10.1080/14756366.2021.1963240

By:

Yan, Meina;
Han, Mutian;
Yang, Xinxin;
Shen, Rong;
Wang, Hui;
Zhang, Lubin;
Xia, Sheng;
Yang, Peifang;
Zhai, Guanghua;
Shao, Qixiang

Publication type:

Article

Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1829, doi. 10.1080/14756366.2021.1960830

By:

Favas, Rita;
Morone, Janaína;
Martins, Rosário;
Vasconcelos, Vitor;
Lopes, Graciliana

Publication type:

Article

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1898, doi. 10.1080/14756366.2021.1960829

By:

Skrzypczak, Natalia;
Pyta, Krystian;
Ruszkowski, Piotr;
Mikołajczak, Przemysław;
Kucińska, Małgorzata;
Murias, Marek;
Gdaniec, Maria;
Bartl, Franz;
Przybylski, Piotr

Publication type:

Article

Carbonic anhydrase activation profile of indole-based derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1783, doi. 10.1080/14756366.2021.1959573

By:

Barresi, Elisabetta;
Ravichandran, Rahul;
Germelli, Lorenzo;
Angeli, Andrea;
Baglini, Emma;
Salerno, Silvia;
Marini, Anna Maria;
Costa, Barbara;
Da Pozzo, Eleonora;
Martini, Claudia;
Da Settimo, Federico;
Supuran, Claudiu;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1952, doi. 10.1080/14756366.2021.1959572

By:

Racané, Livio;
Rep, Valentina;
Kraljević Pavelić, Sandra;
Grbčić, Petra;
Zonjić, Iva;
Radić Stojković, Marijana;
Taylor, Martin C.;
Kelly, John M.;
Raić-Malić, Silvana

Publication type:

Article

Structure–activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1860, doi. 10.1080/14756366.2021.1959571

By:

Wu, Chengyao;
Zhang, Guijuan;
Zhang, Zai-Wei;
Jiang, Xia;
Zhang, Ziwen;
Li, Huanhuan;
Qin, Hua-Li;
Tang, Wenjian

Publication type:

Article

Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1693, doi. 10.1080/14756366.2021.1958213

By:

Wang, Guangcheng;
Liu, Wenjing;
Fan, Meiyan;
He, Min;
Li, Yongjun;
Peng, Zhiyun

Publication type:

Article

New benzothieno[2,3-c]pyridines as non-steroidal CYP17 inhibitors: design, synthesis, anticancer screening, apoptosis induction, and in silico ADME profile studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1839, doi. 10.1080/14756366.2021.1958212

By:

Khalil, Nadia A.;
Ahmed, Eman M.;
Zaher, Ashraf F.;
Sobh, Eman A.;
El-Sebaey, Samiha A.;
El-Zoghbi, Mona S.

Publication type:

Article

Discovery of N-aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents in vitro and in vivo via activating the Hippo signalling pathway.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1715, doi. 10.1080/14756366.2021.1958211

By:

Niu, Jin-Bo;
Quan, Chun-Hua;
Liu, Yuan;
Yu, Guang-Xi;
Yang, Jia-Jia;
Li, Yin-Ru;
Zhang, Yan-Bing;
Qi, Ying-Qiu;
Song, Jian;
Jin, Cheng-Yun;
Zhang, Sai-Yang

Publication type:

Article

Identifying requirements for RSK2 specific inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1798, doi. 10.1080/14756366.2021.1957862

By:

Wright, Eric B.;
Fukuda, Shinji;
Li, Mingzong;
Li, Yu;
O'Doherty, George A.;
Lannigan, Deborah A.

Publication type:

Article

Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1751, doi. 10.1080/14756366.2021.1956914

By:

Murthy, Vallabhaneni S.;
Tamboli, Yasinalli;
Krishna, Vagolu Siva;
Sriram, Dharmarajan;
Akber Ansari, Siddique;
Alarfaj, Abdullah A.;
Hirad, Abdurahman H.;
Vijayakumar, Vijayaparthasarathi

Publication type:

Article

Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1874, doi. 10.1080/14756366.2021.1956913

By:

Baglini, Emma;
Ravichandran, Rahul;
Berrino, Emanuela;
Salerno, Silvia;
Barresi, Elisabetta;
Marini, Anna Maria;
Viviano, Monica;
Castellano, Sabrina;
Da Settimo, Federico;
Supuran, Claudiu T.;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1810, doi. 10.1080/14756366.2021.1956912

By:

Sakr, Asmaa;
Rezq, Samar;
Ibrahim, Samy M.;
Soliman, Eman;
Baraka, Mohamed M.;
Romero, Damian G.;
Kothayer, Hend

Publication type:

Article

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1760, doi. 10.1080/14756366.2021.1956488

By:

Alanazi, Mohammed M.;
Eissa, Ibrahim H.;
Alsaif, Nawaf A.;
Obaidullah, Ahmad J.;
Alanazi, Wael A.;
Alasmari, Abdullah F.;
Albassam, Hussam;
Elkady, Hazem;
Elwan, Alaa

Publication type:

Article

Synthesis and biological evaluations of oleanolic acid indole derivatives as hyaluronidase inhibitors with enhanced skin permeability.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1664, doi. 10.1080/14756366.2021.1956487

By:

He, Hao;
Li, Huifang;
Akanji, Toyosi;
Niu, Shengli;
Luo, Zhujun;
Li, Dongli;
Seeram, Navindra P.;
Wu, Panpan;
Ma, Hang

Publication type:

Article

Strained contacts with the cell membrane may influence ligand affinity to G protein coupled receptors: a case of free fatty acid receptor 1 agonists.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1650, doi. 10.1080/14756366.2021.1955874

By:

Lukin, Alexey;
Bakholdina, Anna;
Chudinov, Mikhail;
Onopchenko, Oleksandra;
Zhuravel, Elena;
Zozulya, Sergey;
Gureev, Maxim;
Krasavin, Mikhail

Publication type:

Article

The role of mTOR in age-related diseases.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1678, doi. 10.1080/14756366.2021.1955873

By:

Chrienova, Zofia;
Nepovimova, Eugenie;
Kuca, Kamil

Publication type:

Article

Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1645, doi. 10.1080/14756366.2021.1954919

By:

Pavan, Matteo;
Bolcato, Giovanni;
Bassani, Davide;
Sturlese, Mattia;
Moro, Stefano

Publication type:

Article

New azolyl-derivatives as multitargeting agents against breast cancer and fungal infections: synthesis, biological evaluation and docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1631, doi. 10.1080/14756366.2021.1954918

By:

Maccallini, Cristina;
Gallorini, Marialucia;
Sisto, Francesca;
Akdemir, Atilla;
Ammazzalorso, Alessandra;
De Filippis, Barbara;
Fantacuzzi, Marialuigia;
Giampietro, Letizia;
Carradori, Simone;
Cataldi, Amelia;
Amoroso, Rosa

Publication type:

Article

Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1658, doi. 10.1080/14756366.2021.1954917

By:

Evangelista, Tereza Cristina Santos;
López, Óscar;
Ferreira, Sabrina Baptista;
Fernández-Bolaños, José G.;
Sydnes, Magne O.;
Lindbäck, Emil

Publication type:

Article

Synthesis and anti-hepatocellular carcinoma activity of aminopyridinol–sorafenib hybrids.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1884, doi. 10.1080/14756366.2021.1953997

By:

Awasthi, Bhuwan Prasad;
Chaudhary, Prakash;
Guragain, Diwakar;
Jee, Jun-Goo;
Kim, Jung-Ae;
Jeong, Byeong-Seon

Publication type:

Article

Trifluoromethyl-substituted 3,5-bis(arylidene)-4-piperidones as potential anti-hepatoma and anti-inflammation agents by inhibiting NF-кB activation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1621, doi. 10.1080/14756366.2021.1953996

By:

Cong, Wei;
Sun, Yue;
Sun, Yi-Fan;
Yan, Wei-Bin;
Zhang, Yu-Long;
Gao, Zhong-Fei;
Wang, Chun-Hua;
Hou, Gui-Ge;
Zhang, Jia-Jing

Publication type:

Article

CO<sub>2</sub> permeability of the rat erythrocyte membrane and its inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1601, doi. 10.1080/14756366.2021.1952194

By:

Al-Samir, Samer;
Prill, Maximilian;
Supuran, Claudiu T.;
Gros, Gerolf;
Endeward, Volker

Publication type:

Article

Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1551, doi. 10.1080/14756366.2021.1948841

By:

Cruz-López, Olga;
Ner, Matilde;
Nerín-Fonz, Francho;
Jiménez-Martínez, Yaiza;
Araripe, David;
Marchal, Juan A.;
Boulaiz, Houria;
Gutiérrez-de-Terán, Hugo;
Campos, Joaquín M.;
Conejo-García, Ana

Publication type:

Article

Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1539, doi. 10.1080/14756366.2021.1948542

By:

Zhang, Lishun;
Yang, Zichao;
Sang, Huiting;
Jiang, Ying;
Zhou, Mingfeng;
Huang, Chuan;
Huang, Chunhui;
Wu, Xiaoyun;
Zhang, Tingting;
Zhang, Xingmei;
Wan, Shanhe;
Zhang, Jiajie

Publication type:

Article

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1487, doi. 10.1080/14756366.2021.1946044

By:

Fares, Salma;
Selim, Khalid B.;
Goda, Fatma E.;
El-Sayed, Magda A. A.;
AlSaif, Nawaf A.;
Hefnawy, Mohamed M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.

Publication type:

Article

Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1732, doi. 10.1080/14756366.2021.1945591

By:

Alanazi, Mohammed M.;
Elwan, Alaa;
Alsaif, Nawaf A.;
Obaidullah, Ahmad J.;
Alkahtani, Hamad M.;
Al-Mehizia, Abdulrahman A.;
Alsubaie, Sultan M.;
Taghour, Mohammed S.;
Eissa, Ibrahim H.

Publication type:

Article