Works in Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, Vol 34, Issue 1

Results: 171

Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1716, doi. 10.1080/14756366.2019.1671837

By:

Im, Daseul;
Moon, Hyungwoo;
Kim, Jingwoong;
Oh, Youri;
Jang, Miyoung;
Hah, Jung-Mi

Publication type:

Article

Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1722, doi. 10.1080/14756366.2019.1670657

By:

Bilginer, Sinan;
Gul, Halise Inci;
Erdal, Feyza Sena;
Sakagami, Hiroshi;
Levent, Serkan;
Gulcin, Ilhami;
Supuran, Claudiu T.

Publication type:

Article

1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1730, doi. 10.1080/14756366.2019.1662790

By:

Jian, Yanlin;
Risseeuw, Martijn D. P.;
Froeyen, Mathy;
Song, Lijun;
Cappoen, Davie;
Cos, Paul;
Munier-Lehmann, Hélène;
van Calenbergh, Serge

Publication type:

Article

Exosomes in head and neck cancer. Updating and revisiting.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1641, doi. 10.1080/14756366.2019.1662000

By:

Zorrilla, Samuel Rodríguez;
García, Abel García;
Carrión, Andrés Blanco;
Vila, Pilar Gándara;
Martín, Manuel Somoza;
Torreira, Mercedes Gallas;
Sayans, Mario Pérez

Publication type:

Article

Blocking the FKBP12 induced dendrimeric burst in aberrant aggregation of α-synuclein by using the ElteN378 synthetic inhibitor.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1711, doi. 10.1080/14756366.2019.1667342

By:

Caminati, Gabriella;
Martina, Maria Raffaella;
Menichetti, Stefano;
Procacci, Piero

Publication type:

Article

Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a review.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1652, doi. 10.1080/14756366.2019.1664501

By:

Akocak, Suleyman;
Supuran, Claudiu T.

Publication type:

Article

Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1678, doi. 10.1080/14756366.2019.1664499

By:

Guo, Wei-Yun;
Chen, Liu-Zeng;
Shen, Bang-Nian;
Liu, Xin-Hua;
Tai, Guang-Ping;
Li, Qing-Shan;
Gao, Li;
Ruan, Ban-Feng

Publication type:

Article

Anti-Helicobacter pylori activity of ethoxzolamide.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1660, doi. 10.1080/14756366.2019.1663416

By:

Modak, Joyanta K.;
Tikhomirova, Alexandra;
Gorrell, Rebecca J.;
Rahman, Mohammad M.;
Kotsanas, Despina;
Korman, Tony M.;
Garcia-Bustos, Jose;
Kwok, Terry;
Ferrero, Richard L.;
Supuran, Claudiu T.;
Roujeinikova, Anna

Publication type:

Article

Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFR<sup>wt</sup>-TK inhibitor.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1668, doi. 10.1080/14756366.2019.1667341

By:

Zhang, Yaling;
Chen, Li;
Li, Xiabing;
Gao, Li;
Hao, Yunxia;
Li, Baolin;
Yan, Yaping

Publication type:

Article

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1697, doi. 10.1080/14756366.2019.1666836

By:

Milite, Ciro;
Amendola, Giorgio;
Nocentini, Alessio;
Bua, Silvia;
Cipriano, Alessandra;
Barresi, Elisabetta;
Feoli, Alessandra;
Novellino, Ettore;
Da Settimo, Federico;
Supuran, Claudiu T.;
Castellano, Sabrina;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Novel tyrosinase inhibitory peptide with free radical scavenging ability.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1633, doi. 10.1080/14756366.2019.1661401

By:

Shen, Zhiwei;
Wang, Yujiao;
Guo, Zhen;
Tan, Tingyuan;
Zhang, Yi

Publication type:

Article

Extraction and derivatisation of active polysaccharides.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1690, doi. 10.1080/14756366.2019.1660654

By:

Liu, Yang;
Huang, Gangliang

Publication type:

Article

Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1623, doi. 10.1080/14756366.2019.1660653

By:

Jenis, Janar;
Baiseitova, Aizhamal;
Yoon, Sang Hwa;
Park, Chanin;
Kim, Jeong Yoon;
Li, Zuo Peng;
Lee, Keun Woo;
Park, Ki Hun

Publication type:

Article

An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed joints.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1615, doi. 10.1080/14756366.2019.1659791

By:

Ji, Min Jeong;
Hong, Jeong Hee

Publication type:

Article

Synthesis and bioevaluation of novel steroidal isatin conjugates derived from epiandrosterone/androsterone.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1607, doi. 10.1080/14756366.2019.1659790

By:

Ke, Shaoyong;
Zhang, Zhigang;
Liu, Manli;
Fang, Wei;
Huang, Daye;
Wan, Zhongyi;
Zhou, Ronghua;
Wang, Kaimei;
Shi, Liqiao

Publication type:

Article

Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1544, doi. 10.1080/14756366.2019.1655407

By:

Chen, Hao;
Qiao, Chao;
Miao, Ting-Ting;
Li, A-Liang;
Wang, Wen-Yan;
Gu, Wen

Publication type:

Article

Design and application of oral colon administration system.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1590, doi. 10.1080/14756366.2019.1655406

By:

Cheng, Hao;
Huang, Shiyu;
Huang, Gangliang

Publication type:

Article

Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1526, doi. 10.1080/14756366.2019.1654470

By:

Distinto, Simona;
Meleddu, Rita;
Ortuso, Francesco;
Cottiglia, Filippo;
Deplano, Serenella;
Sequeira, Lisa;
Melis, Claudia;
Fois, Benedetta;
Angeli, Andrea;
Capasso, Clemente;
Angius, Rossella;
Alcaro, Stefano;
Supuran, Claudiu T.;
Maccioni, Elias

Publication type:

Article

Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1597, doi. 10.1080/14756366.2019.1654469

By:

Lao, Kejing;
Xun, Guoliang;
Gou, Xingchun;
Xiang, Hua

Publication type:

Article

Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1562, doi. 10.1080/14756366.2019.1654468

By:

Rafiq, Muhammad;
Nazir, Yasir;
Ashraf, Zaman;
Rafique, Hummera;
Afzal, Samina;
Mumtaz, Amara;
Hassan, Mubashir;
Ali, Anser;
Afzal, Khurram;
Yousuf, Muhammad Rizwan;
Saleem, Muhammad;
Kotwica-Mojzych, Katarzyna;
Mojzych, Mariusz

Publication type:

Article

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1511, doi. 10.1080/14756366.2019.1653864

By:

Guglielmi, Paolo;
Secci, Daniela;
Petzer, Anél;
Bagetta, Donatella;
Chimenti, Paola;
Rotondi, Giulia;
Ferrante, Claudio;
Recinella, Lucia;
Leone, Sheila;
Alcaro, Stefano;
Zengin, Gokhan;
Petzer, Jacobus P.;
Ortuso, Francesco;
Carradori, Simone

Publication type:

Article

Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moieties.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1534, doi. 10.1080/14756366.2019.1653292

By:

Gamal El-Din, Mahmoud M.;
El-Gamal, Mohammed I.;
Abdel-Maksoud, Mohammed S.;
Yoo, Kyung Ho;
Oh, Chang-Hyun

Publication type:

Article

Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1498, doi. 10.1080/14756366.2019.1653291

By:

Langella, Emma;
Alterio, Vincenzo;
D'Ambrosio, Katia;
Cadoni, Roberta;
Winum, Jean-Yves;
Supuran, Claudiu T.;
Monti, Simona Maria;
De Simone, Giuseppina;
Di Fiore, Anna

Publication type:

Article

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1506, doi. 10.1080/14756366.2019.1653290

By:

De Simone, Giuseppina;
Di Fiore, Anna;
Truppo, Emanuela;
Langella, Emma;
Vullo, Daniela;
Supuran, Claudiu T.;
Monti, Simona Maria

Publication type:

Article

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1457, doi. 10.1080/14756366.2019.1652282

By:

Al-Sanea, Mohammad M.;
Elkamhawy, Ahmed;
Paik, Sora;
Bua, Silvia;
Ha Lee, So;
Abdelgawad, Mohamed A.;
Roh, Eun Joo;
Eldehna, Wagdy M.;
Supuran, Claudiu T.

Publication type:

Article

Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1573, doi. 10.1080/14756366.2019.1651723

By:

Jaballah, Maiy Y.;
Serya, Rabah A. T.;
Saad, Nasser;
Khojah, Sohair M.;
Ahmed, Marawan;
Barakat, Khaled;
Abouzid, Khaled A. M.

Publication type:

Article

Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1465, doi. 10.1080/14756366.2019.1651722

By:

Sabatier, Laureano L.;
Palestro, Pablo H.;
Enrique, Andrea V.;
Pastore, Valentina;
Sbaraglini, María L.;
Martín, Pedro;
Gavernet, Luciana

Publication type:

Article

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1400, doi. 10.1080/14756366.2019.1651315

By:

Rotondi, Giulia;
Guglielmi, Paolo;
Carradori, Simone;
Secci, Daniela;
De Monte, Celeste;
De Filippis, Barbara;
Maccallini, Cristina;
Amoroso, Rosa;
Cirilli, Roberto;
Akdemir, Atilla;
Angeli, Andrea;
Supuran, Claudiu T.

Publication type:

Article

Synthesis and enzyme-based evaluation of analogues L-tyrosine thiol carboxylic acid inhibitor of metallo-β-lactamase IMP-1.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1414, doi. 10.1080/14756366.2019.1651314

By:

Khalili Arjomandi, Omid;
Kavoosi, Mahboubeh;
Adibi, Hadi

Publication type:

Article

New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1388, doi. 10.1080/14756366.2019.1651313

By:

Ugwuja, D. I.;
Okoro, U. C.;
Soman, S. S.;
Soni, R.;
Okafor, S. N.;
Ugwu, D. I.

Publication type:

Article

A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1474, doi. 10.1080/14756366.2019.1651312

By:

Menden, Ariane;
Hall, Davane;
Paris, Daniel;
Mathura, Venkatarian;
Crawford, Fiona;
Mullan, Michael;
Crynen, Stefan;
Ait-Ghezala, Ghania

Publication type:

Article

Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1439, doi. 10.1080/14756366.2019.1651311

By:

Teixeira, Bárbara Velame Ferreira;
Teles, André Lacerda Braga;
Silva, Suellen Gonçalves da;
Brito, Camila Carane Bitencourt;
Freitas, Humberto Fonseca de;
Pires, Acássia Benjamim Leal;
Froes, Thamires Quadros;
Castilho, Marcelo Santos

Publication type:

Article

Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1373, doi. 10.1080/14756366.2019.1644329

By:

Atatreh, Noor;
Al Rawashdah, Sara;
Al Neyadi, Shaikha S.;
Abuhamdah, Sawsan M.;
Ghattas, Mohammad A.

Publication type:

Article

Novel 2-phenoxypyrido[3,2-b]pyrazin-3(4H)-one derivatives as potent and selective aldose reductase inhibitors with antioxidant activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1368, doi. 10.1080/14756366.2019.1643336

By:

Hao, Xin;
Qi, Gang;
Ma, Hongxing;
Zhu, Changjin;
Han, Zhongfei

Publication type:

Article

Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1347, doi. 10.1080/14756366.2019.1642883

By:

Elmeligie, Salwa;
Aboul-Magd, Asmaa M.;
Lasheen, Deena S.;
Ibrahim, Tamer M.;
Abdelghany, Tamer M.;
Khojah, Sohair M.;
Abouzid, Khaled A. M.

Publication type:

Article

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1321, doi. 10.1080/14756366.2019.1640692

By:

Issa, Samar;
Prandina, Anthony;
Bedel, Nicolas;
Rongved, Pål;
Yous, Saïd;
Le Borgne, Marc;
Bouaziz, Zouhair

Publication type:

Article

Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1481, doi. 10.1080/14756366.2019.1640218

By:

Kwon, Mincheol;
Ko, Sung-Kyun;
Jang, Mina;
Kim, Gun-Hee;
Ryoo, In-Ja;
Son, Sangkeun;
Ryu, Hyung Won;
Oh, Sei-Ryang;
Lee, Won-Kyu;
Kim, Bo Yeon;
Jang, Jae-Hyuk;
Ahn, Jong Seog

Publication type:

Article

Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1380, doi. 10.1080/14756366.2019.1639696

By:

Liu, Jia;
Liu, Chunlai;
Zhang, Xiling;
Yu, Liu;
Gong, Xue;
Wang, Ping

Publication type:

Article

10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1298, doi. 10.1080/14756366.2019.1639695

By:

Morak-Młodawska, Beata;
Pluta, Krystian;
Latocha, Małgorzata;
Jeleń, Małgorzata;
Kuśmierz, Dariusz;
Suwińska, Kinga;
Shkurenko, Aleksander;
Czuba, Zenon;
Jurzak, Magdalena

Publication type:

Article

Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1426, doi. 10.1080/14756366.2019.1639694

By:

Nam, Yunju;
Hwang, Dongkeun;
Kim, Namdoo;
Seo, Hong-Seog;
Selim, Khalid B.;
Sim, Taebo

Publication type:

Article

Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1259, doi. 10.1080/14756366.2019.1637861

By:

Othman, Ismail M. M.;
Gad-Elkareem, Mohamed A. M.;
El-Naggar, Mohamed;
Nossier, Eman S.;
Amr, Abd El-Galil E.

Publication type:

Article

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1218, doi. 10.1080/14756366.2019.1636235

By:

Raingeval, Claire;
Cala, Olivier;
Brion, Béatrice;
Le Borgne, Marc;
Hubbard, Roderick Eliot;
Krimm, Isabelle

Publication type:

Article

Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1451, doi. 10.1080/14756366.2019.1636234

By:

Maseko, Sibusiso;
Padayachee, Eden;
Maphumulo, Siyabonga;
Govender, Thavendran;
Sayed, Yasien;
Maguire, Glenn;
Lin, Johnson;
Naicker, Tricia;
Baijnath, Sooraj;
Gerhardus, Kruger Hendrik

Publication type:

Article

Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1210, doi. 10.1080/14756366.2019.1636044

By:

Sun, Xian-yu;
Zhong, Chun-yan;
Qiu, Qing-qing;
Li, Zhen-wang;
Liu, Mei-yu;
Wang, Xin;
Jin, Cheng-hao

Publication type:

Article

Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1287, doi. 10.1080/14756366.2019.1635124

By:

Su, Chang-Ming;
Hou, Gui-Ge;
Wang, Chun-Hua;
Zhang, Hong-Qin;
Yang, Cheng;
Liu, Mei;
Hou, Yun

Publication type:

Article

Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1233, doi. 10.1080/14756366.2019.1634704

By:

Ye, Lianbao;
Zhao, Tao;
Du, Wenjun;
Li, Anhu;
Gao, Wei;
Li, Jingrong;
Wang, Ling;
Chen, Weiqiang

Publication type:

Article

Dual-target anti-Alzheimer's disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1489, doi. 10.1080/14756366.2019.1634703

By:

Mi, Zhisheng;
Gan, Bing;
Yu, Sihang;
Guo, Jianan;
Zhang, Changjun;
Jiang, Xiaoying;
Zhou, Tao;
Su, Jing;
Bai, Renren;
Xie, Yuanyuan

Publication type:

Article

Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1271, doi. 10.1080/14756366.2019.1634064

By:

Herman, Bianka Edina;
Kiss, Anita;
Wölfling, János;
Mernyák, Erzsébet;
Szécsi, Mihály;
Schneider, Gyula

Publication type:

Article

The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1178, doi. 10.1080/14756366.2019.1630617

By:

Angeli, Andrea;
Del Prete, Sonia;
Pinteala, Mariana;
Maier, Stelian S.;
Donald, William A.;
Simionescu, Bogdan C.;
Capasso, Clemente;
Supuran, Claudiu T.

Publication type:

Article

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1193, doi. 10.1080/14756366.2019.1630616

By:

Akocak, Suleyman;
Lolak, Nabih;
Bua, Silvia;
Nocentini, Alessio;
Supuran, Claudiu T.

Publication type:

Article