Works matching IS 14749718 AND DT 2019 AND VI 18 AND IP 3

Results: 47

Announcement.

Published in:: Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12963
Publication type:: Article

Corrigendum.

Published in:: Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12962
Publication type:: Article

Noncoding variations in Cyp24a1 gene are associated with Klotho‐mediated aging phenotypes in different strains of mice.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12949

By:

Singh, Amit;
Verma, Anjali;
Sallin, Michelle A.;
Lang, Florian;
Sen, Ranjan;
Sen, Jyoti Misra

Publication type:

Article

Effects of IGF‐1 isoforms on muscle growth and sarcopenia.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12954

By:

Ascenzi, Francesca;
Barberi, Laura;
Dobrowolny, Gabriella;
Villa Nova Bacurau, Aline;
Nicoletti, Carmine;
Rizzuto, Emanuele;
Rosenthal, Nadia;
Scicchitano, Bianca Maria;
Musarò, Antonio

Publication type:

Article

Glycine supplementation extends lifespan of male and female mice.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12953

By:

Miller, Richard A.;
Harrison, David E.;
Astle, C. Michael;
Bogue, Molly A.;
Brind, Joel;
Fernandez, Elizabeth;
Flurkey, Kevin;
Javors, Martin;
Ladiges, Warren;
Leeuwenburgh, Christiaan;
Macchiarini, Francesca;
Nelson, James;
Ryazanov, Alexey G.;
Snyder, Jessica;
Stearns, Timothy M.;
Vaughan, Douglas E.;
Strong, Randy

Publication type:

Article

1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12951

By:

Chen, Lulu;
Yang, Renlei;
Qiao, Wanxin;
Zhang, Wei;
Chen, Jie;
Mao, Li;
Goltzman, David;
Miao, Dengshun

Publication type:

Article

Targeting senescent cells alleviates obesity‐induced metabolic dysfunction.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12950

By:

Palmer, Allyson K.;
Xu, Ming;
Zhu, Yi;
Pirtskhalava, Tamar;
Weivoda, Megan M.;
Hachfeld, Christine M.;
Prata, Larissa G.;
Dijk, Theo H.;
Verkade, Esther;
Casaclang‐Verzosa, Grace;
Johnson, Kurt O.;
Cubro, Hajrunisa;
Doornebal, Ewald J.;
Ogrodnik, Mikolaj;
Jurk, Diana;
Jensen, Michael D.;
Chini, Eduardo N.;
Miller, Jordan D.;
Matveyenko, Aleksey;
Stout, Michael B.

Publication type:

Article

NMNAT2‐mediated NAD+ generation is essential for quality control of aged oocytes.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12955

By:

Wu, Xinghan;
Hu, Feifei;
Zeng, Juan;
Han, Longsen;
Qiu, Danhong;
Wang, Haichao;
Ge, Juan;
Ying, Xiaoyan;
Wang, Qiang

Publication type:

Article

Long‐term caloric restriction ameliorates deleterious effects of aging on white and brown adipose tissue plasticity.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12948

By:

Corrales, Patricia;
Vivas, Yurena;
Izquierdo‐Lahuerta, Adriana;
Horrillo, Daniel;
Seoane‐Collazo, Patricia;
Velasco, Ismael;
Torres, Lucia;
Lopez, Yamila;
Martínez, Carmen;
López, Miguel;
Ros, Manuel;
Obregon, Maria Jesus;
Medina‐Gomez, Gema

Publication type:

Article

SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long‐lived Myc hypomorphic mice.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12947

By:

Zhao, Xiaoai;
Petrashen, Anna P.;
Sanders, Jennifer A.;
Peterson, Abigail L.;
Sedivy, John M.

Publication type:

Article

IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12946

By:

Wiggins, Kimberley A.;
Parry, Aled J.;
Cassidy, Liam D.;
Humphry, Melanie;
Webster, Steve J.;
Goodall, Jane C.;
Narita, Masashi;
Clarke, Murray C. H.

Publication type:

Article

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12945

By:

Walaszczyk, Anna;
Dookun, Emily;
Redgrave, Rachael;
Tual‐Chalot, Simon;
Victorelli, Stella;
Spyridopoulos, Ioakim;
Owens, Andrew;
Arthur, Helen M.;
Passos, João F.;
Richardson, Gavin D.

Publication type:

Article

Hyperadrenocorticism of calorie restriction contributes to its anti‐inflammatory action in mice.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12944

By:

Allen, Brian D.;
Liao, Chen‐Yu;
Shu, Jianhua;
Muglia, Louis J.;
Majzoub, Joseph A.;
Diaz, Vivian;
Nelson, James F.

Publication type:

Article

mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12943

By:

Tang, Huibin;
Inoki, Ken;
Brooks, Susan V.;
Okazawa, Hideki;
Lee, Myung;
Wang, Junying;
Kim, Michael;
Kennedy, Catherine L.;
Macpherson, Peter C. D.;
Ji, Xuhuai;
Van Roekel, Sabrina;
Fraga, Danielle A.;
Wang, Kun;
Zhu, Jinguo;
Wang, Yoyo;
Sharp, Zelton D.;
Miller, Richard A.;
Rando, Thomas A.;
Goldman, Daniel;
Guan, Kun‐Liang

Publication type:

Article

Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12941

By:

Song, Chengjie;
Zhang, Jun;
Qi, Shasha;
Liu, Zhen;
Zhang, Xiaoyang;
Zheng, Yue;
Andersen, John‐Paul;
Zhang, Weiping;
Strong, Randy;
Martinez, Paul Anthony;
Musi, Nicolas;
Nie, Jia;
Shi, Yuguang

Publication type:

Article

KCNQ1OT1 promotes autophagy by regulating miR‐200a/FOXO3/ATG7 pathway in cerebral ischemic stroke.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12940

By:

Yu, Shijia;
Yu, Mingjun;
He, Xin;
Wen, Lulu;
Bu, Zhongqi;
Feng, Juan

Publication type:

Article

Hormone replacement therapy attenuates hearing loss: Mechanisms involving estrogen and the IGF‐1 pathway.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12939

By:

Williamson, Tanika T.;
Ding, Bo;
Zhu, Xiaoxia;
Frisina, Robert D.

Publication type:

Article

Decoy fitness peaks, tumor suppression, and aging.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12938

By:

Higa, Kelly C.;
DeGregori, James

Publication type:

Article

Vascular smooth muscle cell‐specific progerin expression in a mouse model of Hutchinson–Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12936

By:

del Campo, Lara;
Sánchez‐López, Amanda;
Salaices, Mercedes;
von Kleeck, Ryan A.;
Expósito, Elba;
González‐Gómez, Cristina;
Cussó, Lorena;
Guzmán‐Martínez, Gabriela;
Ruiz‐Cabello, Jesús;
Desco, Manuel;
Assoian, Richard K.;
Briones, Ana M.;
Andrés, Vicente

Publication type:

Article

Astrocyte senescence: Evidence and significance.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12937

By:

Cohen, Justin;
Torres, Claudio

Publication type:

Article

Aged‐senescent cells contribute to impaired heart regeneration.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12931

By:

Lewis‐McDougall, Fiona C.;
Ruchaya, Prashant J.;
Domenjo‐Vila, Eva;
Shin Teoh, Tze;
Prata, Larissa;
Cottle, Beverley J.;
Clark, James E.;
Punjabi, Prakash P.;
Awad, Wael;
Torella, Daniele;
Tchkonia, Tamara;
Kirkland, James L.;
Ellison‐Hughes, Georgina M.

Publication type:

Article

NAD+ supplementation rejuvenates aged gut adult stem cells.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12935

By:

Igarashi, Masaki;
Miura, Masaomi;
Williams, Eric;
Jaksch, Frank;
Kadowaki, Takashi;
Yamauchi, Toshimasa;
Guarente, Leonard

Publication type:

Article

An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12933

By:

Gnani, Daniela;
Crippa, Stefania;
della Volpe, Lucrezia;
Rossella, Valeria;
Conti, Anastasia;
Lettera, Emanuele;
Rivis, Silvia;
Ometti, Marco;
Fraschini, Gianfranco;
Bernardo, Maria Ester;
Di Micco, Raffaella

Publication type:

Article

Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12932

By:

Martín‐Segura, Adrián;
Ahmed, Tariq;
Casadomé‐Perales, Álvaro;
Palomares‐Perez, Irene;
Palomer, Ernest;
Kerstens, Axelle;
Munck, Sebastian;
Balschun, Detlef;
Dotti, Carlos G.

Publication type:

Article

Short‐term starvation stress at young adult stages enhances meiotic activity of germ cells to maintain spermatogenesis in aged male Caenorhabditis elegans.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12930

By:

Chou, Wan‐Yi;
Lin, Yu‐Chun;
Lee, Ying‐Hue

Publication type:

Article

Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12923

By:

Kim, Ha‐Neui;
Chang, Jianhui;
Iyer, Srividhya;
Han, Li;
Campisi, Judith;
Manolagas, Stavros C.;
Zhou, Daohong;
Almeida, Maria

Publication type:

Article

Tendinosis develops from age‐ and oxygen tension‐dependent modulation of Rac1 activity.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12934

By:

McBeath, Rowena;
Edwards, Richard W.;
O'Hara, Brian J.;
Maltenfort, Mitchell G.;
Parks, Susan M.;
Steplewski, Andrzej;
Osterman, A. Lee;
Shapiro, Irving M.

Publication type:

Article

Increased intron retention is a post‐transcriptional signature associated with progressive aging and Alzheimer's disease.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12928

By:

Adusumalli, Swarnaseetha;
Ngian, Zhen‐Kai;
Lin, Wei‐Qi;
Benoukraf, Touati;
Ong, Chin‐Tong

Publication type:

Article

Systemic clearance of p16INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12927

By:

Patil, Prashanti;
Dong, Qing;
Wang, Dong;
Chang, Jianhui;
Wiley, Christopher;
Demaria, Marco;
Lee, Joon;
Kang, James;
Niedernhofer, Laura J.;
Robbins, Paul D.;
Sowa, Gwendolyn;
Campisi, Judith;
Zhou, Daohong;
Vo, Nam

Publication type:

Article

The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12918

By:

Xu, Shun;
Wu, Weijia;
Huang, Haijiao;
Huang, Ruxiao;
Xie, Luoyijun;
Su, Ailing;
Liu, Shuang;
Zheng, Ruinian;
Yuan, Yuan;
Zheng, Hui‐ling;
Sun, Xuerong;
Xiong, Xing‐dong;
Liu, Xinguang

Publication type:

Article

Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12924

By:

Theurey, Pierre;
Connolly, Niamh M. C.;
Fortunati, Ilaria;
Basso, Emy;
Lauwen, Susette;
Ferrante, Camilla;
Moreira Pinho, Catarina;
Joselin, Alvin;
Gioran, Anna;
Bano, Daniele;
Park, David S.;
Ankarcrona, Maria;
Pizzo, Paola;
Prehn, Jochen H. M.

Publication type:

Article

Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR‐132/MeCP2 pathway.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12929

By:

Xie, Ao‐Ji;
Hou, Tong‐Yao;
Xiong, Wan;
Huang, He‐Zhou;
Zheng, Jie;
Li, Ke;
Man, Heng‐Ye;
Hu, Ya‐Zhuo;
Han, Zhi‐Tao;
Zhang, Hong‐Hong;
Wei, Na;
Wang, Jian‐Zhi;
Liu, Dan;
Lu, Youming;
Zhu, Ling‐Qiang

Publication type:

Article

Caloric restriction controls stationary phase survival through Protein Kinase A (PKA) and cytosolic pH.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12921

By:

Dolz‐Edo, Laura;
van der Deen, Margaretha;
Brul, Stanley;
Smits, Gertien Jacoba

Publication type:

Article

Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12919

By:

Trujillo‐Estrada, Laura;
Nguyen, Cassidy;
da Cunha, Celia;
Cai, Lena;
Forner, Stefania;
Martini, Alessandra C.;
Ager, Rahasson R.;
Prieto, Gilberto Aleph;
Cotman, Carl W.;
Baglietto‐Vargas, David;
LaFerla, Frank M.

Publication type:

Article

Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12926

By:

Headley, Colwyn A.;
Gerberick, Abigail;
Mehta, Sumiran;
Wu, Qian;
Yu, Lianbo;
Fadda, Paolo;
Khan, Mahmood;
Ganesan, Latha Prabha;
Turner, Joanne;
Rajaram, Murugesan V. S.

Publication type:

Article

The exceptional longevity of the naked mole‐rat may be explained by mitochondrial antioxidant defenses.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12916

By:

Munro, Daniel;
Baldy, Cécile;
Pamenter, Matthew E.;
Treberg, Jason R.

Publication type:

Article

Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12914

By:

Kim, So‐Jin;
Shan, Peiying;
Hwangbo, Cheol;
Zhang, Yi;
Min, Jin‐Na;
Zhang, Xuchen;
Ardito, Taylor;
Li, Alfred;
Peng, Tien;
Sauler, Maor;
Lee, Patty J.

Publication type:

Article

The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12913

By:

Romero, Alejandra;
San Hipólito‐Luengo, Álvaro;
Villalobos, Laura A.;
Vallejo, Susana;
Valencia, Inés;
Michalska, Patrycja;
Pajuelo‐Lozano, Natalia;
Sánchez‐Pérez, Isabel;
León, Rafael;
Bartha, José Luis;
Sanz, María Jesús;
Erusalimsky, Jorge D.;
Sánchez‐Ferrer, Carlos F.;
Romacho, Tania;
Peiró, Concepción

Publication type:

Article

Dynamin‐like protein 1 cleavage by calpain in Alzheimer's disease.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12912

By:

Jiang, Sirui;
Shao, Changjuan;
Tang, Fangqiang;
Wang, Wenzhang;
Zhu, Xiongwei

Publication type:

Article

KIN‐4/MAST kinase promotes PTEN‐mediated longevity of Caenorhabditis elegans via binding through a PDZ domain.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12906

By:

An, Seon Woo A.;
Choi, Eun‐Seok;
Hwang, Wooseon;
Son, Heehwa G.;
Yang, Jae‐Seong;
Seo, Keunhee;
Nam, Hyun‐Jun;
Nguyen, Nhung T. H.;
Kim, Eun Ji E.;
Suh, Bo Kyoung;
Kim, Youngran;
Nakano, Shunji;
Ryu, Youngjae;
Man Ha, Chang;
Mori, Ikue;
Park, Sang Ki;
Yoo, Joo‐Yeon;
Kim, Sanguk;
Lee, Seung‐Jae V.

Publication type:

Article

Genetically heterogeneous mice exhibit a female survival advantage that is age‐ and site‐specific: Results from a large multi‐site study.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12905

By:

Cheng, Catherine J.;
Gelfond, Jonathan A. L.;
Strong, Randy;
Nelson, James F.

Publication type:

Article

Accelerated bio‐cognitive aging in Down syndrome: State of the art and possible deceleration strategies.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12903

By:

Franceschi, Claudio;
Garagnani, Paolo;
Gensous, Noémie;
Bacalini, Maria Giulia;
Conte, Maria;
Salvioli, Stefano

Publication type:

Article

DAF‐16 stabilizes the aging transcriptome and is activated in mid‐aged Caenorhabditis elegans to cope with internal stress.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12896

By:

Li, Shang‐Tong;
Zhao, Han‐Qing;
Zhang, Pan;
Liang, Chung‐Yi;
Zhang, Yan‐Ping;
Hsu, Ao‐Lin;
Dong, Meng‐Qiu

Publication type:

Article

PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12887

By:

Tible, Marion;
Mouton Liger, François;
Schmitt, Julien;
Giralt, Albert;
Farid, Karim;
Thomasseau, Sylvie;
Gourmaud, Sarah;
Paquet, Claire;
Rondi Reig, Laure;
Meurs, Eliane;
Girault, Jean‐Antoine;
Hugon, Jacques

Publication type:

Article

The leptin sensitizer celastrol reduces age‐associated obesity and modulates behavioral rhythms.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12874

By:

Chellappa, Karthikeyani;
Perron, Isaac J.;
Naidoo, Nirinjini;
Baur, Joseph A.

Publication type:

Article

JNK modifies neuronal metabolism to promote proteostasis and longevity.

Published in:

Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12849

By:

Wang, Lifen;
Davis, Sonnet S.;
Borch Jensen, Martin;
Rodriguez‐Fernandez, Imilce A.;
Apaydin, Cagsar;
Juhasz, Gabor;
Gibson, Bradford W.;
Schilling, Birgit;
Ramanathan, Arvind;
Ghaemmaghami, Sina;
Jasper, Heinrich

Publication type:

Article

Issue Information.

Published in:: Aging Cell, 2019, v. 18, n. 3, p. N.PAG, doi. 10.1111/acel.12805
Publication type:: Article