Works matching IS 14749718 AND DT 2018 AND VI 17 AND IP 4

Results: 44

Announcement.

Published in:: Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12826
Publication type:: Article

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age‐associated insulin resistance.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12798

By:

Gulshan, Maryam;
Yaku, Keisuke;
Okabe, Keisuke;
Mahmood, Arshad;
Sasaki, Tsutomu;
Yamamoto, Masashi;
Hikosaka, Keisuke;
Usui, Isao;
Kitamura, Tadahiro;
Tobe, Kazuyuki;
Nakagawa, Takashi

Publication type:

Article

Spontaneous development of Alzheimer's disease‐associated brain pathology in a Shugoshin‐1 mouse cohesinopathy model.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12797

By:

Rao, Chinthalapally V.;
Farooqui, Mudassir;
Zhang, Yuting;
Asch, Adam S.;
Yamada, Hiroshi Y.

Publication type:

Article

Role of dietary amino acid balance in diet restriction‐mediated lifespan extension, renoprotection, and muscle weakness in aged mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12796

By:

Yoshida, Shohei;
Yamahara, Kosuke;
Kume, Shinji;
Koya, Daisuke;
Yasuda‐Yamahara, Mako;
Takeda, Naoko;
Osawa, Norihisa;
Chin‐Kanasaki, Masami;
Adachi, Yusuke;
Nagao, Kenji;
Maegawa, Hiroshi;
Araki, Shin‐ichi

Publication type:

Article

Differential aging‐related changes in neurophysiology and gene expression in IB4‐positive and IB4‐negative nociceptive neurons.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12795

By:

Mis, Malgorzata A.;
Rogers, Mark F.;
Jeffries, Aaron R.;
Wilbrey, Anna L.;
Chen, Lubin;
Yang, Yang;
Dib‐Hajj, Sulayman;
Waxman, Stephen G.;
Stevens, Edward B.;
Randall, Andrew D.

Publication type:

Article

MicroRNA‐31a‐5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12794

By:

Xu, Rongyao;
Shen, Xiang;
Si, Yameng;
Fu, Yu;
Zhu, Weiwen;
Xiao, Tao;
Fu, Zongyun;
Zhang, Ping;
Cheng, Jie;
Jiang, Hongbing

Publication type:

Article

Mitochondria and aging: A role for the mitochondrial transition pore?

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12793

By:

Panel, Mathieu;
Ghaleh, Bijan;
Morin, Didier

Publication type:

Article

Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12792

By:

Wang, Yu‐Chen;
Lee, An‐Sheng;
Lu, Long‐Sheng;
Ke, Liang‐Yin;
Chen, Wei‐Yu;
Dong, Jian‐Wen;
Lu, Jonathan;
Chen, Zhenping;
Chu, Chih‐Sheng;
Chan, Hua‐Chen;
Kuzan, Taha Y.;
Tsai, Ming‐Hsien;
Hsu, Wen‐Li;
Dixon, Richard A. F.;
Sawamura, Tatsuya;
Chang, Kuan‐Cheng;
Chen, Chu‐Huang

Publication type:

Article

Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12791

By:

Baglietto‐Vargas, David;
Prieto, Gilberto Aleph;
Limon, Agenor;
Forner, Stefania;
Rodriguez‐Ortiz, Carlos J.;
Ikemura, Kenji;
Ager, Rahasson R.;
Medeiros, Rodrigo;
Trujillo‐Estrada, Laura;
Martini, Alessandra C.;
Kitazawa, Masashi;
Davila, Jose C.;
Cotman, Carl W.;
Gutierrez, Antonia;
LaFerla, Frank M.

Publication type:

Article

Glucocorticoid‐mediated modulation of morphological changes associated with aging in microglia.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12790

By:

van Olst, Lynn;
Bielefeld, Pascal;
Fitzsimons, Carlos P.;
de Vries, Helga E.;
Schouten, Marijn

Publication type:

Article

SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12789

By:

Zeng, Juan;
Jiang, Manxi;
Wu, Xinghan;
Diao, Feiyang;
Qiu, Danhong;
Hou, Xiaojing;
Wang, Haichao;
Li, Ling;
Li, Chunling;
Ge, Juan;
Liu, Jiayin;
Ou, Xianghong;
Wang, Qiang

Publication type:

Article

Synergistic effects of TGFβ2, WNT9a, and FGFR4 signals attenuate satellite cell differentiation during skeletal muscle development.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12788

By:

Zhang, Weiya;
Xu, Yueyuan;
Zhang, Lu;
Wang, Sheng;
Yin, Binxu;
Zhao, Shuhong;
Li, Xinyun

Publication type:

Article

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12787

By:

Solesio, María E.;
Peixoto, Pablo M.;
Debure, Ludovic;
Madamba, Stephen M.;
de Leon, Mony J.;
Wisniewski, Thomas;
Pavlov, Evgeny V.;
Fossati, Silvia

Publication type:

Article

Male lifespan extension with 17‐α estradiol is linked to a sex‐specific metabolomic response modulated by gonadal hormones in mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12786

By:

Garratt, Michael;
Lagerborg, Kim A.;
Tsai, Yi‐Miau;
Galecki, Andrzej;
Jain, Mohit;
Miller, Richard A.

Publication type:

Article

Extracellular RNA profiles with human age.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12785

By:

Dluzen, Douglas F.;
Noren Hooten, Nicole;
De, Supriyo;
Wood III, William H.;
Zhang, Yongqing;
Becker, Kevin G.;
Zonderman, Alan B.;
Tanaka, Toshiko;
Ferrucci, Luigi;
Evans, Michele K.

Publication type:

Article

Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre‐implantation embryos.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12784

By:

Wang, Tianren;
Babayev, Elnur;
Jiang, Zongliang;
Li, Guangxin;
Zhang, Man;
Esencan, Ecem;
Horvath, Tamas;
Seli, Emre

Publication type:

Article

CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12783

By:

Gu, Peili;
Jia, Shuting;
Takasugi, Taylor;
Smith, Eric;
Nandakumar, Jayakrishnan;
Hendrickson, Eric;
Chang, Sandy

Publication type:

Article

Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12775

By:

Velazquez, Ramon;
Ferreira, Eric;
Tran, An;
Turner, Emily C.;
Belfiore, Ramona;
Branca, Caterina;
Oddo, Salvatore

Publication type:

Article

Corrigendum.

Published in:: 2018
Publication type:: Correction Notice

Apolipoprotein E region molecular signatures of Alzheimer's disease.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12779

By:

Kulminski, Alexander M.;
Huang, Jian;
Wang, Jiayi;
He, Liang;
Loika, Yury;
Culminskaya, Irina

Publication type:

Article

Social stress shortens lifespan in mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12778

By:

Razzoli, Maria;
Nyuyki‐Dufe, Kewir;
Gurney, Allison;
Erickson, Connor;
McCallum, Jacob;
Spielman, Nicholas;
Marzullo, Marta;
Patricelli, Jessica;
Kurata, Morito;
Pope, Emily A.;
Touma, Chadi;
Palme, Rupert;
Largaespada, David A.;
Allison, David B.;
Bartolomucci, Alessandro

Publication type:

Article

Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12777

By:

Bejarano, Eloy;
Murray, John W.;
Wang, Xintao;
Pampliega, Olatz;
Yin, David;
Patel, Bindi;
Yuste, Andrea;
Wolkoff, Allan W.;
Cuervo, Ana Maria

Publication type:

Article

Hypothalamic Sirt1 protects terminal Schwann cells and neuromuscular junctions from age‐related morphological changes.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12776

By:

Snyder‐Warwick, Alison K.;
Satoh, Akiko;
Santosa, Katherine B.;
Imai, Shin‐ichiro;
Jablonka‐Shariff, Albina

Publication type:

Article

Oxidation resistance 1 is a novel senolytic target.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12780

By:

Zhang, Xin;
Zhang, Suping;
Liu, Xingui;
Wang, Yingying;
Chang, Jianhui;
Zhang, Xuan;
Mackintosh, Samuel G.;
Tackett, Alan J.;
He, Yonghan;
Lv, Dongwen;
Laberge, Remi‐Martin;
Campisi, Judith;
Wang, Jianrong;
Zheng, Guangrong;
Zhou, Daohong

Publication type:

Article

Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12774

By:

Ji, Juan;
Xue, Teng‐Fei;
Guo, Xu‐Dong;
Yang, Jin;
Guo, Ruo‐Bing;
Wang, Juan;
Huang, Ji‐Ye;
Zhao, Xiao‐Jie;
Sun, Xiu‐Lan

Publication type:

Article

Overexpression of CYB5R3 and NQO1, two NAD+‐producing enzymes, mimics aspects of caloric restriction.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12767

By:

Diaz‐Ruiz, Alberto;
Lanasa, Michael;
Garcia, Joseph;
Mora, Hector;
Fan, Frances;
Martin‐Montalvo, Alejandro;
Di Francesco, Andrea;
Calvo‐Rubio, Miguel;
Salvador‐Pascual, Andrea;
Aon, Miguel A.;
Fishbein, Kenneth W.;
Pearson, Kevin J.;
Villalba, Jose Manuel;
Navas, Placido;
Bernier, Michel;
de Cabo, Rafael

Publication type:

Article

Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12773

By:

Foote, Kirsty;
Reinhold, Johannes;
Yu, Emma P. K.;
Figg, Nichola L.;
Finigan, Alison;
Murphy, Michael P.;
Bennett, Martin R.

Publication type:

Article

Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12771

By:

Diekman, Brian O.;
Sessions, Garrett A.;
Collins, John A.;
Knecht, Anne K.;
Strum, Susan L.;
Mitin, Natalia K.;
Carlson, Cathy S.;
Loeser, Richard F.;
Sharpless, Norman E.

Publication type:

Article

Necroptosis increases with age and is reduced by dietary restriction.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12770

By:

Deepa, Sathyaseelan S.;
Unnikrishnan, Archana;
Matyi, Stephanie;
Hadad, Niran;
Richardson, Arlan

Publication type:

Article

Glucagon‐like peptide‐1 ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via the PPARα pathway.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12763

By:

Wu, Lujin;
Wang, Ke;
Wang, Wei;
Wen, Zheng;
Wang, Peihua;
Liu, Lei;
Wang, Dao Wen

Publication type:

Article

Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12769

By:

Deepa, Sathyaseelan S.;
Pharaoh, Gavin;
Kinter, Michael;
Diaz, Vivian;
Fok, Wilson C.;
Riddle, Kaitlyn;
Pulliam, Daniel;
Hill, Shauna;
Fischer, Kathleen E.;
Soto, Vanessa;
Georgescu, Constantin;
Wren, Jonathan D.;
Viscomi, Carlo;
Richardson, Arlan;
Van Remmen, Holly

Publication type:

Article

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12772

By:

Cuyàs, Elisabet;
Verdura, Sara;
Llorach‐Pares, Laura;
Fernández‐Arroyo, Salvador;
Luciano‐Mateo, Fedra;
Cabré, Noemí;
Stursa, Jan;
Werner, Lukas;
Martin‐Castillo, Begoña;
Viollet, Benoit;
Neuzil, Jiri;
Joven, Jorge;
Nonell‐Canals, Alfons;
Sanchez‐Martinez, Melchor;
Menendez, Javier A.

Publication type:

Article

MicroRNAs in hereditary and sporadic premature aging syndromes and other laminopathies.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12766

By:

Frankel, Diane;
Delecourt, Valérie;
Harhouri, Karim;
De Sandre‐Giovannoli, Annachiara;
Lévy, Nicolas;
Kaspi, Elise;
Roll, Patrice

Publication type:

Article

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12765

By:

Fang, Jingqi;
Yang, Jiping;
Wu, Xun;
Zhang, Gangming;
Li, Tao;
Wang, Xi'e;
Zhang, Hong;
Wang, Chih‐chen;
Liu, Guang‐Hui;
Wang, Lei

Publication type:

Article

Advanced oxidation protein products induce pre‐osteoblast apoptosis through a nicotinamide adenine dinucleotide phosphate oxidase‐dependent, mitogen‐activated protein kinases‐mediated intrinsic apoptosis pathway.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12764

By:

Zhu, Si‐Yuan;
Zhuang, Jing‐Shen;
Wu, Qian;
Liu, Zhong‐Yuan;
Liao, Cong‐Rui;
Luo, Shi‐Gan;
Chen, Jian‐Ting;
Zhong, Zhao‐Ming

Publication type:

Article

Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12768

By:

Li, Dang;
Ke, Yilang;
Zhan, Rui;
Liu, Changjie;
Zhao, Mingming;
Zeng, Aiping;
Shi, Xiaoyun;
Ji, Liang;
Cheng, Si;
Pan, Bing;
Zheng, Lemin;
Hong, Huashan

Publication type:

Article

Activation of DNA demethylases attenuates aging‐associated arterial stiffening and hypertension.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12762

By:

Chen, Kai;
Sun, Zhongjie

Publication type:

Article

Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12761

By:

Chun, Sung Kook;
Lee, Sooyeon;
Flores‐Toro, Joseph;
U, Rebecca Y.;
Yang, Ming‐Jim;
Go, Kristina L.;
Biel, Thomas G.;
Miney, Catherine E.;
Pierre Louis, Schiley;
Law, Brian K.;
Law, Mary E.;
Thomas, Elizabeth M.;
Behrns, Kevin E.;
Leeuwenburgh, Christiaan;
Kim, Jae‐Sung

Publication type:

Article

SUMO1‐conjugation is altered during normal aging but not by increased amyloid burden.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12760

By:

Stankova, Trayana;
Piepkorn, Lars;
Bayer, Thomas A.;
Jahn, Olaf;
Tirard, Marilyn

Publication type:

Article

Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12751

By:

Vatner, Dorothy E.;
Zhang, Jie;
Oydanich, Marko;
Guers, John;
Katsyuba, Elena;
Yan, Lin;
Sinclair, David;
Auwerx, Johan;
Vatner, Stephen F.

Publication type:

Article

Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12740

By:

Ma, Siming;
Avanesov, Andrei S.;
Porter, Emily;
Lee, Byung Cheon;
Mariotti, Marco;
Zemskaya, Nadezhda;
Guigo, Roderic;
Moskalev, Alexey A.;
Gladyshev, Vadim N.

Publication type:

Article

Mice with reduced expression of the telomere‐associated protein Ft1 develop p53‐sensitive progeroid traits.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12730

By:

La Torre, Mattia;
Merigliano, Chiara;
Burla, Romina;
Mottini, Carla;
Zanetti, Giorgia;
Del Giudice, Simona;
Carcuro, Mariateresa;
Virdia, Ilaria;
Bucciarelli, Elisabetta;
Manni, Isabella;
Vinciguerra, Gianluca Rampioni;
Piaggio, Giulia;
Riminucci, Mara;
Cumano, Ana;
Bartolazzi, Armando;
Vernì, Fiammetta;
Soddu, Silvia;
Gatti, Maurizio;
Saggio, Isabella

Publication type:

Article

HTRA1, an age‐related macular degeneration protease, processes extracellular matrix proteins EFEMP1 and TSP1.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12710

By:

Lin, Michael K.;
Yang, Jin;
Hsu, Chun Wei;
Gore, Anuradha;
Bassuk, Alexander G.;
Brown, Lewis M.;
Colligan, Ryan;
Sengillo, Jesse D.;
Mahajan, Vinit B.;
Tsang, Stephen H.

Publication type:

Article

Issue Information.

Published in:: Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12670
Publication type:: Article