Works matching IS 14741776 AND DT 2015 AND VI 14 AND IP 7
Results: 25
An analysis of the attrition of drug candidates from four major pharmaceutical companies.
- Published in:
- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 475, doi. 10.1038/nrd4609
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- Article
Regulatory watch: Why do oncology drugs fail to gain US regulatory approval?
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 450, doi. 10.1038/nrd4651
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- Article
Rational drug design: Tuning kinase inhibitor residence time.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 457, doi. 10.1038/nrd4673
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Improving R&D productivity.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 455, doi. 10.1038/nrd4650
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Assessing the relative efficacy of new drugs: an emerging opportunity.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 443, doi. 10.1038/nrd4664
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Asthma: DNAzyme attenuates allergic asthma.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 460, doi. 10.1038/nrd4677
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- Article
Oncolytic viruses get a boost with first FDA-approval recommendation.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 510, doi. 10.1038/nrd4680
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Anticancer drugs: Selectively targeting proteins for degradation.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 459, doi. 10.1038/nrd4670
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- Article
Robust biotech sector increases R&D spend.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 449, doi. 10.1038/nrd4687
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Prospects for the development of epigenetic drugs for CNS conditions.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 461, doi. 10.1038/nrd4580
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Cancer: LOX does some prepping.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 458, doi. 10.1038/nrd4674
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- Article
Infectious disease: Fragment screening identifies novel HIV-1 RT inhibitors.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 460, doi. 10.1038/nrd4678
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Should the FDA disclose complete response letters?
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 449, doi. 10.1038/nrd4686
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The pharmacology of second-generation chimeric antigen receptors.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 499, doi. 10.1038/nrd4597
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- Article
Autoimmune disease: SIRT1 inhibition suppresses multiple sclerosis.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 460, doi. 10.1038/nrd4679
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- Article
Moncef Slaoui.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 452, doi. 10.1038/nrd4669
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- Article
Obesity: Reversing resistance to leptin in obesity.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 458, doi. 10.1038/nrd4671
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- Article
A β-lactamase inhibitor revival provides new hope for old antibiotics.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 445, doi. 10.1038/nrd4666
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- Article
Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: the force awakens.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 487, doi. 10.1038/nrd4506
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- Article
Fibrotic diseases: New tools to target an elusive integrin.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 460, doi. 10.1038/nrd4672
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- Article
Academic drug discovery within the United Kingdom: a reassessment.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 510, doi. 10.1038/nrd4661
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- Article
FDA approves two IBS drugs.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 449, doi. 10.1038/nrd4688
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- Article
The NASH drug dash.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 447, doi. 10.1038/nrd4667
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- Article
Chronic kidney disease: Targeting dynamin oligomerization.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 460, doi. 10.1038/nrd4676
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Market watch: Upcoming market catalysts in Q3 2015.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 451, doi. 10.1038/nrd4668
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- Article