Works matching IS 14741776 AND DT 2015 AND VI 14 AND IP 3

Results: 30

What does it take to produce a breakthrough drug?

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 161, doi. 10.1038/nrd4570

By:

Calcoen, Dirk;
Elias, Laura;
Yu, Xiaomeng

Publication type:

Article

Regulatory watch: Efficiency indicators for new drugs approved by the FDA from 2003 to 2013.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 156, doi. 10.1038/nrd4563

By:

Belleli, Rossella;
Fisch, Roland;
Szucs, Thomas D.

Publication type:

Article

Unleashing the therapeutic potential of human kallikrein-related serine proteases.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 183, doi. 10.1038/nrd4534

By:

Prassas, Ioannis;
Eissa, Azza;
Poda, Gennadiy;
Diamandis, Eleftherios P.

Publication type:

Article

Mike Varney.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 158, doi. 10.1038/nrd4566

By:

Varney, Mike

Publication type:

Article

Infectious diseases: Towards a new class of tuberculosis drugs.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 166, doi. 10.1038/nrd4574

By:

Crunkhorn, Sarah

Publication type:

Article

Advances in the development of influenza virus vaccines.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 167, doi. 10.1038/nrd4529

By:

Krammer, Florian;
Palese, Peter

Publication type:

Article

Cancer stem cells: Targeting the root of cancer relapse.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 165, doi. 10.1038/nrd4560

By:

Flemming, Alexandra

Publication type:

Article

$215 million precision-medicine initiative takes shape.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 155, doi. 10.1038/nrd4569

By:

Mullard, Asher

Publication type:

Article

Fragile X disappointments upset autism ambitions.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 151, doi. 10.1038/nrd4555

By:

Mullard, Asher

Publication type:

Article

Principles in the design of ligand-targeted cancer therapeutics and imaging agents.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 203, doi. 10.1038/nrd4519

By:

Srinivasarao, Madduri;
Galliford, Chris V.;
Low, Philip S.

Publication type:

Article

Preclinical target validation using patient-derived cells.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 149, doi. 10.1038/nrd4565

By:

Edwards, Aled M.;
Arrowsmith, Cheryl H.;
Bountra, Chas;
Bunnage, Mark E.;
Feldmann, Marc;
Knight, Julian C.;
Patel, Dhavalkumar D.;
Prinos, Panagiotis;
Taylor, Michael D.;
Sundström, Michael;
Barker, Phil;
Barsyte, Dalia;
Bengtson, Mario H.;
Bell, Cindy;
Bowness, Paul;
Boycott, Kym M.;
Buser-Doepner, Carolyn;
Carpenter, Christopher L.;
Carr, Andrew J.;
Clark, Kirk

Publication type:

Article

Charting the decline of US biomedical research funding.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 155, doi. 10.1038/nrd4567

By:

Mullard, Asher

Publication type:

Article

Natural products: Enhancing production.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 166, doi. 10.1038/nrd4577

By:

Crunkhorn, Sarah

Publication type:

Article

Anticancer agents: An alternative route to targeting telomere elongation.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 164, doi. 10.1038/nrd4558

By:

Crunkhorn, Sarah

Publication type:

Article

Fibrotic disease: Fixing a feedback loop in fibrosis.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 163, doi. 10.1038/nrd4559

By:

Bray, Natasha

Publication type:

Article

Endometriosis: Suppressing the oestrogen-inflammatory axis.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 166, doi. 10.1038/nrd4576

By:

Crunkhorn, Sarah

Publication type:

Article

Progression-seeking bias and rational optimism in research and development.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 219, doi. 10.1038/nrd4320-c1

By:

Lendrem, Dennis W.;
Lendrem, B. Clare;
Peck, Richard W.;
Senn, Stephen C.;
Day, Simon;
Isaacs, John D.

Publication type:

Article

New twist on antibiotic hunt hits pay dirt.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 153, doi. 10.1038/nrd4556

By:

Katsnelson, Alla

Publication type:

Article

Stroke: Meddling with the mind.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 166, doi. 10.1038/nrd4561

By:

Bordon, Yvonne

Publication type:

Article

Cardiovascular disease: MYDGF promotes heart repair after myocardial infarction.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 164, doi. 10.1038/nrd4557

By:

Cully, Megan

Publication type:

Article

Patent watch: US Supreme Court revises patent claim construction standards.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 157, doi. 10.1038/nrd4564

By:

Noonan, Kevin

Publication type:

Article

Antibody design: Hormone-CDR fusions enhance hormone efficacy.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 166, doi. 10.1038/nrd4575

By:

Crunkhorn, Sarah

Publication type:

Article

Roche buys $1 billion majority stake in Foundation.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 155, doi. 10.1038/nrd4568

By:

Mullard, Asher

Publication type:

Article

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 3, p. 219, doi. 10.1038/nrd4579

By:

Falkenberg, Katrina J.;
Johnstone, Ricky W.

Publication type:

Article

Advances in the development of influenza virus vaccines.

Published in:

2015

By:

Krammer, Florian;
Palese, Peter

Publication type:

journal article

Stroke: Meddling with the mind.

Published in:

2015

By:

Bordon, Yvonne

Publication type:

journal article

Cancer stem cells: Targeting the root of cancer relapse.

Published in:

2015

By:

Flemming, Alexandra

Publication type:

Journal Article

Cardiovascular disease: MYDGF promotes heart repair after myocardial infarction.

Published in:

2015

By:

Cully, Megan

Publication type:

journal article

Anticancer agents: An alternative route to targeting telomere elongation.

Published in:

2015

By:

Crunkhorn, Sarah

Publication type:

journal article

Fibrotic disease: Fixing a feedback loop in fibrosis.

Published in:

2015

By:

Bray, Natasha

Publication type:

journal article