Works matching IS 14741776 AND DT 2013 AND VI 12 AND IP 12

Results: 31

The risks of risk aversion in drug regulation.

Published in:

2013

By:

Eichler, Hans-Georg;
Bloechl-Daum, Brigitte;
Brasseur, Daniel;
Breckenridge, Alasdair;
Leufkens, Hubert;
Raine, June;
Salmonson, Tomas;
Schneider, Christian K;
Rasi, Guido

Publication type:

journal article

Chemical predictive modelling to improve compound quality.

Published in:

2013

By:

Cumming, John G;
Davis, Andrew M;
Muresan, Sorel;
Haeberlein, Markus;
Chen, Hongming

Publication type:

journal article

Histone lysine demethylases as targets for anticancer therapy.

Published in:

2013

By:

Højfeldt, Jonas W;
Agger, Karl;
Helin, Kristian

Publication type:

journal article

Metabolic targets for cancer therapy.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 963, doi. 10.1038/nrd4191

By:

Galluzzi, Lorenzo;
Kepp, Oliver;
Heiden, Matthew G. Vander;
Kroemer, Guido

Publication type:

Article

Target identification: Blocking vasopressin receptors reduces jet lag.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 903, doi. 10.1038/nrd4180

By:

Tse, Man Tsuey

Publication type:

Article

Time to rethink dose-finding study design.

Published in:: Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 895, doi. 10.1038/nrd4193
Publication type:: Article

Autoimmune disease: Parkinson's drug promotes myelin repair.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 905, doi. 10.1038/nrd4181

By:

Crunkhorn, Sarah

Publication type:

Article

Market watch: Defining and quantifying the use of personalized medicines.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 896, doi. 10.1038/nrd4177

By:

Hu, Sean X.;
Aitken, Murray L.;
Epstein, Arnold M.;
Trusheim, Mark R.;
Berndt, Ernst R.

Publication type:

Article

Modulation of oxidative stress as an anticancer strategy.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 931, doi. 10.1038/nrd4002

By:

Gorrini, Chiara;
Harris, Isaac S.;
Mak, Tak W.

Publication type:

Article

The value of single-pathogen antibacterial agents.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 963, doi. 10.1038/nrd3957-c1

By:

Spellberg, Brad;
Rex, John H.

Publication type:

Article

Chemical predictive modelling to improve compound quality.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 948, doi. 10.1038/nrd4128

By:

Cumming, John G.;
Davis, Andrew M.;
Muresan, Sorel;
Haeberlein, Markus;
Chen, Hongming

Publication type:

Article

The GHIT fund shows its cards.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 894, doi. 10.1038/nrd4197

By:

Holmes, David

Publication type:

Article

Neurodegenerative disease: Tau immunotherapy targets transcellular propagation.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 904, doi. 10.1038/nrd4179

By:

Flight, Monica Hoyos

Publication type:

Article

Learning from the 2012-2013 class of breakthrough therapies.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 891, doi. 10.1038/nrd4196

By:

Mullard, Asher

Publication type:

Article

NIH denies march-in rights on Norvir patent.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 898, doi. 10.1038/nrd4198

By:

Harrison, Charlotte

Publication type:

Article

Does size matter in R&D productivity? If not, what does?

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 901, doi. 10.1038/nrd4164

By:

Ringel, Michael;
Tollman, Peter;
Hersch, Greg;
Schulze, Ulrik

Publication type:

Article

With great speed comes great need for post-marketing oversight?

Published in:: Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 895, doi. 10.1038/nrd4194
Publication type:: Article

Bone disorders: Targeting NOX4 knocks down osteoporosis.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 904, doi. 10.1038/nrd4182

By:

Harrison, Charlotte

Publication type:

Article

VC and non-profit unite to launch new companies.

Published in:: Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 895, doi. 10.1038/nrd4195
Publication type:: Article

Trial watch: Phase II boost for glutamate-targeted antidepressants.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 897, doi. 10.1038/nrd4178

By:

Flight, Monica Hoyos

Publication type:

Article

In this issue.

Published in:: Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 887, doi. 10.1038/nrd4192
Publication type:: Article

Recent patents related to histone demethylases.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 899, doi. 10.1038/nrd4199

By:

Harrison, Charlotte

Publication type:

Article

Neurodegenerative disease: A PERK for the therapy of prion disease.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 906, doi. 10.1038/nrd4185

By:

Harrison, Charlotte

Publication type:

Article

Target validation: Tinkering with heart disease.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 906, doi. 10.1038/nrd4186

By:

Harrison, Charlotte

Publication type:

Article

Neurodegenerative disease: Patient stem cells give clues to ALS.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 906, doi. 10.1038/nrd4187

By:

Harrison, Charlotte

Publication type:

Article

Computational biology: Structural insights into allosteric GPCR drugs.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 906, doi. 10.1038/nrd4188

By:

Harrison, Charlotte

Publication type:

Article

Drugging cancer genomes.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 889, doi. 10.1038/nrd4184

By:

Workman, Paul;
Al-Lazikani, Bissan

Publication type:

Article

Charles Hugh-Jones.

Published in:: Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 900, doi. 10.1038/nrd4190
Publication type:: Article

Neurological disorders: Chloride extrusion alleviates neuropathic pain.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 906, doi. 10.1038/nrd4183

By:

Flemming, Alexandra

Publication type:

Article

Histone lysine demethylases as targets for anticancer therapy.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 917, doi. 10.1038/nrd4154

By:

Højfeldt, Jonas W.;
Agger, Karl;
Helin, Kristian

Publication type:

Article

The risks of risk aversion in drug regulation.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 907, doi. 10.1038/nrd4129

By:

Eichler, Hans-Georg;
Bloechl-Daum, Brigitte;
Brasseur, Daniel;
Breckenridge, Alasdair;
Leufkens, Hubert;
Raine, June;
Salmonson, Tomas;
Schneider, Christian K.;
Rasi, Guido

Publication type:

Article