Works in Cellular & Molecular Life Sciences, 2022, Vol 79, Issue 6

Results: 63

Glycation of α-synuclein hampers its binding to synaptic-like vesicles and its driving effect on their fusion.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04373-4

By:

Uceda, Ana Belén;
Frau, Juan;
Vilanova, Bartolomé;
Adrover, Miquel

Publication type:

Article

Tip-end fusion of a rod-shaped secretory organelle.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04367-2

By:

Naß, Johannes;
Koerdt, Sophia N.;
Biesemann, Anja;
Chehab, Tarek;
Yasuda, Takao;
Fukuda, Mitsunori;
Martín-Belmonte, Fernando;
Gerke, Volker

Publication type:

Article

HIF-1-dependent heme synthesis promotes gemcitabine resistance in human non-small cell lung cancers via enhanced ABCB6 expression.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04360-9

By:

Xiang, Lisha;
Wang, Yongsheng;
Lan, Jie;
Na, Feifei;
Wu, Shuang;
Gong, Yuzhu;
Du, Hanjian;
Shao, Bin;
Xie, Ganfeng

Publication type:

Article

HGprt deficiency disrupts dopaminergic circuit development in a genetic mouse model of Lesch–Nyhan disease.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04326-x

By:

Witteveen, J. S.;
Loopstok, S. R.;
Ballesteros, L. Luque;
Boonstra, A.;
van Bakel, N. H. M.;
van Boekel, W. H. P.;
Martens, G. J. M.;
Visser, J. E.;
Kolk, S. M.

Publication type:

Article

The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.

Published in:

2022

By:

Topchu, Iuliia;
Pangeni, Rajendra P.;
Bychkov, Igor;
Miller, Sven A.;
Izumchenko, Evgeny;
Yu, Jindan;
Golemis, Erica;
Karanicolas, John;
Boumber, Yanis

Publication type:

Literature Review

Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04317-y

By:

Van Loy, Tom;
De Jonghe, Steven;
Castermans, Karolien;
Dheedene, Wouter;
Stoop, Reinout;
Verschuren, Lars;
Versele, Matthias;
Chaltin, Patrick;
Luttun, Aernout;
Schols, Dominique

Publication type:

Article

Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04316-z

By:

Lu, Jing;
Azad, Mohammad A. K.;
Moreau, Julie L. M.;
Zhu, Yan;
Jiang, Xukai;
Tonta, Mary;
Lam, Rachel;
Wickremasinghe, Hasini;
Zhao, Jinxin;
Wang, Jiping;
Coleman, Harold A.;
Formosa, Luke E.;
Velkov, Tony;
Parkington, Helena C.;
Combes, Alexander N.;
Rosenbluh, Joseph;
Li, Jian

Publication type:

Article

Prenatal glucocorticoid exposure selectively impairs neuroligin 1-dependent neurogenesis by suppressing astrocytic FGF2–neuronal FGFR1 axis.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04313-2

By:

Choi, Gee Euhn;
Chae, Chang Woo;
Park, Mo Ran;
Yoon, Jee Hyeon;
Jung, Young Hyun;
Lee, Hyun Jik;
Han, Ho Jae

Publication type:

Article

Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04305-2

By:

Shi, Yue;
Zhao, Kaixuan;
Yang, Guang;
Yu, Jia;
Li, Yuxin;
Kessels, Michael M.;
Yu, Lina;
Qualmann, Britta;
Berggren, Per-Olof;
Yang, Shao-Nian

Publication type:

Article

WNT and NOTCH signaling in human trophoblast development and differentiation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04285-3

By:

Dietrich, Bianca;
Haider, Sandra;
Meinhardt, Gudrun;
Pollheimer, Jürgen;
Knöfler, Martin

Publication type:

Article

Periostin in lymph node pre-metastatic niches governs lymphatic endothelial cell functions and metastatic colonization.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04262-w

By:

Gillot, Lionel;
Lebeau, Alizée;
Baudin, Louis;
Pottier, Charles;
Louis, Thomas;
Durré, Tania;
Longuespée, Rémi;
Mazzucchelli, Gabriel;
Nizet, Christophe;
Blacher, Silvia;
Kridelka, Frédéric;
Noël, Agnès

Publication type:

Article

Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04378-z

By:

Rydbirk, Rasmus;
Østergaard, Ole;
Folke, Jonas;
Hempel, Casper;
DellaValle, Brian;
Andresen, Thomas L.;
Løkkegaard, Annemette;
Hejl, Anne-Mette;
Bode, Matthias;
Blaabjerg, Morten;
Møller, Mette;
Danielsen, Erik H.;
Salvesen, Lisette;
Starhof, Charlotte C.;
Bech, Sara;
Winge, Kristian;
Rungby, Jørgen;
Pakkenberg, Bente;
Brudek, Tomasz;
Olsen, Jesper V.

Publication type:

Article

Early human trophoblast development: from morphology to function.

Published in:

2022

By:

Gauster, Martin;
Moser, Gerit;
Wernitznig, Stefan;
Kupper, Nadja;
Huppertz, Berthold

Publication type:

Literature Review

Essential role of CK2α for the interaction and stability of replication fork factors during DNA synthesis and activation of the S-phase checkpoint.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04374-3

By:

Guerra, Barbara;
Doktor, Thomas K.;
Frederiksen, Sabrina B.;
Somyajit, Kumar;
Andresen, Brage S.

Publication type:

Article

Integrating intracellular nanovesicles into integrin trafficking pathways and beyond.

Published in:

2022

By:

Larocque, Gabrielle;
Royle, Stephen J.

Publication type:

Literature Review

Transcription factor networks in trophoblast development.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04363-6

By:

Papuchova, Henrieta;
Latos, Paulina A.

Publication type:

Article

Contact-dependent signaling triggers tumor-like proliferation of CCM3 knockout endothelial cells in co-culture with wild-type cells.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04355-6

By:

Rath, Matthias;
Schwefel, Konrad;
Malinverno, Matteo;
Skowronek, Dariush;
Leopoldi, Alexandra;
Pilz, Robin A.;
Biedenweg, Doreen;
Bekeschus, Sander;
Penninger, Josef M.;
Dejana, Elisabetta;
Felbor, Ute

Publication type:

Article

SETD2: from chromatin modifier to multipronged regulator of the genome and beyond.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04352-9

By:

Molenaar, Thom M.;
van Leeuwen, Fred

Publication type:

Article

BRD2 interconnects with BRD3 to facilitate Pol II transcription initiation and elongation to prime promoters for cell differentiation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04349-4

By:

Wang, Chenlu;
Xu, Qiqin;
Zhang, Xianhong;
Day, Daniel S.;
Abraham, Brian J.;
Lun, Kehuan;
Chen, Liang;
Huang, Jie;
Ji, Xiong

Publication type:

Article

Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04382-3

By:

Ralevski, Alexandra;
Apelt, Federico;
Olas, Justyna J.;
Mueller-Roeber, Bernd;
Rugarli, Elena I.;
Kragler, Friedrich;
Horvath, Tamas L.

Publication type:

Article

Oxidative stress response pathways in fungi.

Published in:

2022

By:

Yaakoub, Hajar;
Mina, Sara;
Calenda, Alphonse;
Bouchara, Jean-Philippe;
Papon, Nicolas

Publication type:

Literature Review

Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer’s disease neuropathology.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04347-6

By:

Agrawal, Sudhanshu;
Baulch, Janet E.;
Madan, Shreya;
Salah, Seher;
Cheeks, Samantha N.;
Krattli, Robert P. Jr.;
Subramanian, Veedamali S.;
Acharya, Munjal M.;
Agrawal, Anshu

Publication type:

Article

Consequences of the Hsp110DE9 mutation in tumorigenesis and the 5-fluorouracil-based chemotherapy response in Msh2-deficient mice.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04293-3

By:

Noel, Kathleen;
Bokhari, A.’dem;
Bertrand, Romane;
Renaud, Florence;
Bourgoin, Pierre;
Cohen, Romain;
Svrcek, Magali;
Joly, Anne-Christine;
Duval, Alex;
Collura, Ada

Publication type:

Article

Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04357-4

By:

Bub, Annika;
Brenna, Santra;
Alawi, Malik;
Kügler, Paul;
Gui, Yuqi;
Kretz, Oliver;
Altmeppen, Hermann;
Magnus, Tim;
Puig, Berta

Publication type:

Article

ALX1-transcribed LncRNA AC132217.4 promotes osteogenesis and bone healing via IGF-AKT signaling in mesenchymal stem cells.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04338-7

By:

Zhang, Cui;
Wu, Shali;
Chen, Erman;
Yu, Luyang;
Wang, Jinfu;
Wu, Mengrui

Publication type:

Article

Trigeminal neurons control immune-bone cell interaction and metabolism in apical periodontitis.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04335-w

By:

Austah, Obadah N.;
Lillis, Katherine V.;
Akopian, Armen N.;
Harris, Stephen E.;
Grinceviciute, Ruta;
Diogenes, Anibal

Publication type:

Article

Rac1 regulates lipid droplets formation, nanomechanical, and nanostructural changes induced by TNF in vascular endothelium in the isolated murine aorta.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04362-7

By:

Pacia, Marta Z.;
Chorazy, Natalia;
Sternak, Magdalena;
Fels, Benedikt;
Pacia, Michal;
Kepczynski, Mariusz;
Kusche-Vihrog, Kristina;
Chlopicki, Stefan

Publication type:

Article

In vivo impact of JAK3 A573V mutation revealed using zebrafish.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04361-8

By:

Basheer, Faiza;
Bulleeraz, Vilasha;
Ngo, Viet Q. T.;
Liongue, Clifford;
Ward, Alister C.

Publication type:

Article

PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As2O3 by stabilizing oncoprotein PML-RARα.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04358-3

By:

Huang, Xinping;
Yang, Yongfeng;
Zhu, Dan;
Zhao, Yan;
Wei, Min;
Li, Ke;
Zhu, Hong-hu;
Zheng, Xiaofeng

Publication type:

Article

Misaligned feeding schedule elicits divergent circadian reorganizations in endo- and exocrine pancreas clocks.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04354-7

By:

Honzlová, Petra;
Novosadová, Zuzana;
Houdek, Pavel;
Sládek, Martin;
Sumová, Alena

Publication type:

Article

Discovery of surface biomarkers for cell mechanophenotype via an intracellular protein-based enrichment strategy.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04351-w

By:

Dempsey, Megan E.;
Chickering, Graylen R.;
González-Cruz, Rafael D.;
Fonseca, Vera C.;
Darling, Eric M.

Publication type:

Article

Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04346-7

By:

Vanmunster, Mathias;
Rojo Garcia, Ana Victoria;
Pacolet, Alexander;
Dalle, Sebastiaan;
Koppo, Katrien;
Jonkers, Ilse;
Lories, Rik;
Suhr, Frank

Publication type:

Article

Neuroendocrinal and molecular basis of flight performance in locusts.

Published in:

2022

By:

Hou, Li;
Guo, Siyuan;
Ding, Ding;
Du, Baozhen;
Wang, Xianhui

Publication type:

Literature Review

PAI-1 production by reactive astrocytes drives tissue dysfibrinolysis in multiple sclerosis models.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04340-z

By:

Lebas, Héloïse;
Guérit, Sylvaine;
Picot, Audrey;
Boulay, Anne Cécile;
Fournier, Antoine;
Vivien, Denis;
Cohen Salmon, Martine;
Docagne, Fabian;
Bardou, Isabelle

Publication type:

Article

A novel sterol-binding protein reveals heterogeneous cholesterol distribution in neurite outgrowth and in late endosomes/lysosomes.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04339-6

By:

Yamaji-Hasegawa, Akiko;
Murate, Motohide;
Inaba, Takehiko;
Dohmae, Naoshi;
Sato, Masayuki;
Fujimori, Fumihiro;
Sako, Yasushi;
Greimel, Peter;
Kobayashi, Toshihide

Publication type:

Article

Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04312-3

By:

Poświata, Agata;
Kozik, Kamila;
Miączyńska, Marta;
Zdżalik-Bielecka, Daria

Publication type:

Article

Complementary omics strategies to dissect p53 signaling networks under nutrient stress.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04345-8

By:

Galhuber, Markus;
Michenthaler, Helene;
Heininger, Christoph;
Reinisch, Isabel;
Nössing, Christoph;
Krstic, Jelena;
Kupper, Nadja;
Moyschewitz, Elisabeth;
Auer, Martina;
Heitzer, Ellen;
Ulz, Peter;
Birner-Gruenberger, Ruth;
Liesinger, Laura;
Lenihan-Geels, Georgia Ngawai;
Oster, Moritz;
Spreitzer, Emil;
Zenezini Chiozzi, Riccardo;
Schulz, Tim J.;
Schupp, Michael;
Madl, Tobias

Publication type:

Article

Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04325-y

By:

Lurette, Olivier;
Guedouari, Hala;
Morris, Jordan L.;
Martín-Jiménez, Rebeca;
Robichaud, Julie-Pier;
Hamel-Côté, Geneviève;
Khan, Mehtab;
Dauphinee, Nicholas;
Pichaud, Nicolas;
Prudent, Julien;
Hebert-Chatelain, Etienne

Publication type:

Article

Fibrillin-1-regulated miR-122 has a critical role in thoracic aortic aneurysm formation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04337-8

By:

Zhang, Rong-Mo;
Tiedemann, Kerstin;
Muthu, Muthu L.;
Dinesh, Neha E. H.;
Komarova, Svetlana;
Ramkhelawon, Bhama;
Reinhardt, Dieter P.

Publication type:

Article

In vitro inhibition of cancer angiogenesis and migration by a nanobody that targets the orphan receptor Tie1.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04336-9

By:

Meltzer, May;
Eliash, Noam;
Azoulay, Ziv;
Hadad, Uzi;
Papo, Niv

Publication type:

Article

Mechanisms involved in controlling RNA virus-induced intestinal inflammation.

Published in:

2022

By:

Zhang, Evan;
Fang, Mingli;
Jones, Colette;
Minze, Laurie J.;
Xing, Junji;
Zhang, Zhiqiang

Publication type:

Literature Review

Dead Cas(t) light on new life: CRISPRa-mediated reprogramming of somatic cells into neurons.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04324-z

By:

Zhou, Meiling;
Cao, Yu;
Sui, Ming;
Shu, Xiji;
Wan, Feng;
Zhang, Bin

Publication type:

Article

The HLA-G immune checkpoint: a new immuno-stimulatory role for the α1-domain-deleted isoform.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04359-2

By:

Tronik-Le Roux, Diana;
Daouya, Marina;
Jacquier, Alix;
Schenowitz, Chantal;
Desgrandchamps, François;
Rouas-Freiss, Nathalie;
Carosella, Edgardo D.

Publication type:

Article

The novel P330L pathogenic variant of aromatic amino acid decarboxylase maps on the catalytic flexible loop underlying its crucial role.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04343-w

By:

Bisello, Giovanni;
Kusmierska, Katarzyna;
Verbeek, Marcel M.;
Sykut–Cegielska, Jolanta;
Willemsen, Michèl A. A. P.;
Wevers, Ron A.;
Szymańska, Krystyna;
Poznanski, Jarosław;
Drozak, Jakub;
Wertheim–Tysarowska, Katarzyna;
Rygiel, Agnieszka Magdalena;
Bertoldi, Mariarita

Publication type:

Article

Impaired GATE16-mediated exocytosis in exocrine tissues causes Sjögren’s syndrome-like exocrinopathy.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04334-x

By:

Suzuki, Akiko;
Iwaya, Chihiro;
Ogata, Kenichi;
Yoshioka, Hiroki;
Shim, Junbo;
Tanida, Isei;
Komatsu, Masaaki;
Tada, Norihiro;
Iwata, Junichi

Publication type:

Article

Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04333-y

By:

Ka, Na-Lee;
Lim, Ga Young;
Kim, Seung‑Su;
Hwang, Sewon;
Han, Juhyeong;
Lee, Yun-Hee;
Lee, Mi-Ock

Publication type:

Article

Mettl14 mediates the inflammatory response of macrophages in atherosclerosis through the NF-κB/IL-6 signaling pathway.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04331-0

By:

Zheng, Yang;
Li, Yunqi;
Ran, Xianwen;
Wang, Di;
Zheng, Xianghui;
Zhang, Maomao;
Yu, Bo;
Sun, Yong;
Wu, Jian

Publication type:

Article

Nuclear receptor Nr1d1 alleviates asthma by abating GATA3 gene expression and Th2 cell differentiation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04323-0

By:

Tiwari, Drishti;
Ahuja, Nancy;
Kumar, Sumit;
Kalra, Rashi;
Nanduri, Ravikanth;
Gupta, Shalini;
Khare, Asheesh Kumar;
Bhagyaraj, Ella;
Arora, Rashmi;
Gupta, Pawan

Publication type:

Article

Role of LL-37 in thrombotic complications in patients with COVID-19.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04309-y

By:

Duan, Zilei;
Zhang, Juan;
Chen, Xue;
Liu, Ming;
Zhao, Hongwen;
Jin, Lin;
Zhang, Zhiye;
Luan, Ning;
Meng, Ping;
Wang, Jing;
Tan, Zhaoxia;
Li, Yaxiong;
Deng, Guohong;
Lai, Ren

Publication type:

Article

Therapeutic potential of a single-dose melatonin in the attenuation of cardiac ischemia/reperfusion injury in prediabetic obese rats.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04330-1

By:

Singhanat, Kodchanan;
Apaijai, Nattayaporn;
Sumneang, Natticha;
Maneechote, Chayodom;
Arunsak, Busarin;
Chunchai, Titikorn;
Chattipakorn, Siriporn C.;
Chattipakorn, Nipon

Publication type:

Article