Works matching IS 11778881 AND DT 2025 AND VI 19
Results: 87
Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 827, doi. 10.2147/DDDT.S504873
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- Article
The Roles of Forkhead Box O3a (FOXO3a) in Bone and Cartilage Diseases – A Narrative Review.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1357, doi. 10.2147/DDDT.S494841
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- Article
Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 771, doi. 10.2147/DDDT.S504884
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- Article
Effect of Intravenous Dexmedetomidine Premedication on Sufentanil Median Effective Concentration During Tracheal Intubation in Obese Patients: A Randomized Controlled Study.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1323, doi. 10.2147/DDDT.S491599
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- Article
The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1129, doi. 10.2147/DDDT.S503226
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Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 955, doi. 10.2147/DDDT.S493911
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- Article
SHR-1916: A Novel PEGylated Interleukin-2 Analogue with Altered Cellular Selectivity and Improved Pharmacokinetic Profiles for Cancer Immunotherapy.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1251, doi. 10.2147/DDDT.S493011
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- Article
Lipid Nanovesicles in Cancer Treatment: Improving Targeting and Stability of Antisense Oligonucleotides.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1001, doi. 10.2147/DDDT.S507402
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- Article
Recent Advances in Propranolol Hydrochloride Formulations for the Treatment of Infantile Hemangiomas.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1163, doi. 10.2147/DDDT.S496847
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- Article
Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 737, doi. 10.2147/DDDT.S487496
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- Article
Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 877, doi. 10.2147/DDDT.S498238
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- Article
Population Pharmacokinetics of Prolonged Infusion for Meropenem: Tailoring Dosing Recommendations for Chinese Critically Ill Patients on Continuous Renal Replacement Therapy with Consideration for Renal Function.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1105, doi. 10.2147/DDDT.S489603
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- Article
A Bibliometric and Visual Analysis of Oliceridine Research (2013–2024).
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1305, doi. 10.2147/DDDT.S497186
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- Article
Oleanolic Acid Cubic Liquid Crystal Nanoparticle-Based Thermosensitive Gel Attenuates Depression Symptoms in Chronic Unpredictable Mild Stress Rats.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 715, doi. 10.2147/DDDT.S484567
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- Article
NLRP3 Inflammasome Targeting Offers a Novel Therapeutic Paradigm for Sepsis-Induced Myocardial Injury.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1025, doi. 10.2147/DDDT.S506537
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Network Pharmacology and Experimental Verification: Phellodendri Chinensis Cortex-Cnidii Fructus Herb Pair Alleviates Atopic Dermatitis by Regulating the TLR4/NF-κB Pathway.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1451, doi. 10.2147/DDDT.S505248
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- Article
Population Pharmacokinetic of Epidural Sufentanil in Labouring Women: A Multicentric, Prospective, Observational Study.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 971, doi. 10.2147/DDDT.S500189
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- Article
Tempol Mitigates Methotrexate-Induced Osteotoxicity via Oxidative Stress Modulation and MAPK Pathway Inhibition.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1441, doi. 10.2147/DDDT.S510206
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- Article
Metabolomic Analysis, Antiproliferative, Anti-Migratory, and Anti-Invasive Potential of Amlodipine in Lung Cancer Cells.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1215, doi. 10.2147/DDDT.S484561
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- Article
Melatonin Exerts Positive Effects on Sepsis Through Various Beneficial Mechanisms.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1333, doi. 10.2147/DDDT.S509735
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Medication Safety in Intravenous Therapy: Compatibility of Etoposide with Frequently Drugs Used in Tumour Critical Care During Simulated Y-Site Administration.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1147, doi. 10.2147/DDDT.S489534
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- Article
Low-Dose Dexmedetomidine Attenuates the Dose Requirement of Propofol for Suppression of Body Movement in Patients Undergoing Operative Hysteroscopy.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1185, doi. 10.2147/DDDT.S503538
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LncRNA MALAT1/Calpain-1 Axis in ATO Induced hERG Channel Deficiency.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1475, doi. 10.2147/DDDT.S502776
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RET Inhibitor SPP86 Is a Potential Candidate for the Clinical Treatment of Cutaneous Melanoma [Letter].
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1249, doi. 10.2147/DDDT.S523115
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- Article
Lenvatinib Monotherapy Versus Lenvatinib in Combination with PD-1 Blockades as Re-Challenging Treatment for Patients with Metastatic Osteosarcoma: A Real-World Study.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1119, doi. 10.2147/DDDT.S501742
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Irisin Mitigates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Inflammation via Modulation of the PERK-eIF2α-ATF4 Pathway.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1067, doi. 10.2147/DDDT.S492691
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Double-Blind, Placebo-Controlled Trial.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 759, doi. 10.2147/DDDT.S491300
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Identification of Key Genes in Esketamine's Therapeutic Effects on Perioperative Neurocognitive Disorders via Transcriptome Sequencing.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 981, doi. 10.2147/DDDT.S510752
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Health Technology Assessment: Evaluation of 8 CGRP-Targeted Therapy Drugs for the Treatment of Migraine.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1231, doi. 10.2147/DDDT.S499848
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Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1289, doi. 10.2147/DDDT.S486371
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Enteric-Coated Aspirin Induces Small Intestinal Injury via the Nrf2/Gpx4 Pathway: A Promising Model for Chronic Enteropathy.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 891, doi. 10.2147/DDDT.S493049
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Efficacy and Safety of Colquhounia Root Tablet for Chronic Glomerulopathy: A Real-World Survey With Bioinformatics Insights.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1421, doi. 10.2147/DDDT.S488557
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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 931, doi. 10.2147/DDDT.S497554
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Effect of Fentanyl on Remimazolam-Induced Sedation in Female Patients Undergoing Hysteroscopic Surgery: A Randomized Controlled Trial.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1393, doi. 10.2147/DDDT.S504189
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Determination of the MEC90 of Oxycodone for Preventing Perioperative Shivering in Pregnant Patients Undergoing Caesarean Delivery with Neuraxial Anaesthesia: A Biased-Coin up-and-Down Sequential Allocation Trial.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 945, doi. 10.2147/DDDT.S497239
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Design, Synthesis and Evaluation of Novel Cyclopropanesulfonamide Derivatives for the Treatment of EGFR<sup>C797S</sup> Mutation in Non-Small Cell Lung Cancer.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1403, doi. 10.2147/DDDT.S490303
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Danggui-Shaoyao-San Can Ameliorate Alzheimer's Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 911, doi. 10.2147/DDDT.S490900
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Cyanidin and Cyanidin-3-Glucoside Alleviate Peptic Ulcer Disease: Insights from in vitro, and in vivo Studies.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 841, doi. 10.2147/DDDT.S500645
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Cordycepin Ameliorates Renal Interstitial Fibrosis by Inhibiting Drp1-Mediated Mitochondrial Fission.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1271, doi. 10.2147/DDDT.S498525
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Dynamic Visualization of Computer-Aided Peptide Design for Cancer Therapeutics.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1043, doi. 10.2147/DDDT.S497126
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Comprehensive Bioactive Compound Profiling of Artocarpus heterophyllus Leaves: LC-MS/MS Analysis, Antioxidant Potential, and Molecular Insights.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1195, doi. 10.2147/DDDT.S507658
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Combining Network Pharmacology, Molecular Docking and Experimental Validation to Explore the Effects and Mechanisms of Indirubin on Acute Lymphoblastic Leukemia.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1083, doi. 10.2147/DDDT.S500249
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A Comparison of the Effects of Sevoflurane, Propofol, and Propofol Combined with Butorphanol in Suppressing Sufentanil-Induced cough—A Randomized Controlled Trial.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1347, doi. 10.2147/DDDT.S492641
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Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 1377, doi. 10.2147/DDDT.S474398
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- Article
Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 793, doi. 10.2147/DDDT.S509208
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Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 857, doi. 10.2147/DDDT.S498457
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A Randomized Placebo-Controlled Dose-Response Trial of Muvz<sup>™</sup> for Knee and Low-Back Support in Physically Active Adults.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 811, doi. 10.2147/DDDT.S486836
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A Review of the Therapeutic Potential of Ginseng and Its Bioactive Components in Nonalcoholic Fatty Liver Disease.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 83, doi. 10.2147/DDDT.S500719
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The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 525, doi. 10.2147/DDDT.S487074
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Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis.
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- Drug Design, Development & Therapy, 2025, v. 19, p. 251, doi. 10.2147/DDDT.S488226
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