Works in Drug Design, Development & Therapy, 2016, Vol 10
Results: 376
Folic acid-conjugated amphiphilic alternating copolymer as a new active tumor targeting drug delivery platform.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4101, doi. 10.2147/DDDT.S123386
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Structure-based virtual screening and characterization of a novel IL-6 antagonistic compound from synthetic compound database.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4091, doi. 10.2147/DDDT.S118457
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Protective effects of vitamin C and vitamin E against hysterosalpingography-induced epithelial degeneration and proliferation in rat endometrium.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4079, doi. 10.2147/DDDT.S117207
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Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with nontransfusion-dependent thalassemia syndromes.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4073, doi. 10.2147/DDDT.S117080
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Design and in vitro/in vivo evaluation of sustainedrelease floating tablets of itopride hydrochloride.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4061, doi. 10.2147/DDDT.S115909
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Spotlight on fluticasone furoate/vilanterol trifenatate for the once-daily treatment of asthma: design, development and place in therapy.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4047, doi. 10.2147/DDDT.S113573
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Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4017, doi. 10.2147/DDDT.S120356
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Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4031, doi. 10.2147/DDDT.S120613
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Determination of the starting dose in the first-inhuman clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 4005, doi. 10.2147/DDDT.S121520
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Comparison of oral absorption models for pregabalin: usefulness of transit compartment model.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3995, doi. 10.2147/DDDT.S123318
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Use of bedaquiline and delamanid in diabetes patients: clinical and pharmacological considerations.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3983, doi. 10.2147/DDDT.S121630
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Impact of prostaglandin glaucoma drops on platelet-activating factor action: an in vitro study.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3977, doi. 10.2147/DDDT.S117806
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Paracetamol sharpens reflection and spatial memory: a double-blind randomized controlled study in healthy volunteers.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3969, doi. 10.2147/DDDT.S111590
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Efficacy and tolerability of vilazodone for major depressive disorder: evidence from phase III/IV randomized controlled trials.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3899, doi. 10.2147/DDDT.S122085
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Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3879, doi. 10.2147/DDDT.S116192
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Dose-dependent effects of cisplatin on the severity of testicular injury in Sprague Dawley rats: reactive oxygen species and endoplasmic reticulum stress.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3959, doi. 10.2147/DDDT.S120014
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Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3947, doi. 10.2147/DDDT.S123759
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Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3933, doi. 10.2147/DDDT.S116286
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Statistical modeling methods to analyze the impacts of multiunit process variability on critical quality attributes of Chinese herbal medicine tablets.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3909, doi. 10.2147/DDDT.S119122
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Effect of peritoneal dialysis fluid containing osmometabolic agents on human endothelial cells.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3925, doi. 10.2147/DDDT.S117078
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Physicochemical stability of ternary admixtures of butorphanol, ketamine, and droperidol in polyolefin bags for patient-controlled analgesia use.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3873, doi. 10.2147/DDDT.S123411
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Three generations of epidermal growth factor receptor tyrosine kinase inhibitors developed to revolutionize the therapy of lung cancer.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3867, doi. 10.2147/DDDT.S119162
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Design, synthesis and evaluation of VEGF-siRNA/CRS as a novel vector for gene delivery.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3851, doi. 10.2147/DDDT.S118461
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Smart nanocrystals of artemether: fabrication, characterization, and comparative in vitro and in vivo antimalarial evaluation.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3837, doi. 10.2147/DDDT.S114962
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Feasibility of sequential adjuvant chemotherapy with a 3-month oxaliplatin-based regimen followed by 3 months of capecitabine in patients with stage III and high-risk stage II colorectal cancer: JSWOG-C2 study.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3827, doi. 10.2147/DDDT.S112322
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Efficacy and safety of two fixed-dose combinations of S-amlodipine and telmisartan (CKD-828) versus S-amlodipine monotherapy in patients with hypertension inadequately controlled using S-amlodipine monotherapy: an 8-week, multicenter, randomized, double-blind, Phase III clinical study
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3817, doi. 10.2147/DDDT.S116847
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Fabrication of anti-vitiligo ointment containing Psoralea corylifolia: in vitro and in vivo characterization.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3805, doi. 10.2147/DDDT.S114328
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CARD9 as a potential target in cardiovascular disease.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3799, doi. 10.2147/DDDT.S122508
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Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3789, doi. 10.2147/DDDT.S119918
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Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3779, doi. 10.2147/DDDT.S118145
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Dietary arginine silicate inositol complex inhibits periodontal tissue loss in rats with ligatureinduced periodontitis.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3771, doi. 10.2147/DDDT.S115088
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Pharmacokinetics, pharmacodynamics and safety of CKD-519, a CETP inhibitor, in healthy subjects.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3763, doi. 10.2147/DDDT.S120387
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Oncolytic adenovirus expressing interleukin-18 improves antitumor activity of dacarbazine for malignant melanoma.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3755, doi. 10.2147/DDDT.S115121
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Selexipag in the treatment of pulmonary arterial hypertension: design, development, and therapy.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3747, doi. 10.2147/DDDT.S103534
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Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3737, doi. 10.2147/DDDT.S87435
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Systematic review and meta-analysis of randomized controlled trials on Wenxin keli.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3725, doi. 10.2147/DDDT.S112333
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Low-dose modified-release prednisone in axial spondyloarthritis: 3-month efficacy and tolerability.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3717, doi. 10.2147/DDDT.S115099
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Improved oral bioavailability of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol using nanoemulsion based on phospholipid complex: design, characterization, and in vivo pharmacokinetics in rats.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3707, doi. 10.2147/DDDT.S114374
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Effects of resveratrol on P-glycoprotein and cytochrome P450 3A in vitro and on pharmacokinetics of oral saquinavir in rats.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3699, doi. 10.2147/DDDT.S118723
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Ustekinumab in treatment of Crohn's disease: design, development, and potential place in therapy.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3685, doi. 10.2147/DDDT.S102141
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Comment on the case report "Possible association between acetazolamide administration during pregnancy and multiple congenital malformations".
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3681, doi. 10.2147/DDDT.S122748
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More frequent IgD and reduced CD200 expression in Chinese patients younger than 50 years old with multiple myeloma: a multicenter analysis.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3673, doi. 10.2147/DDDT.S100062
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Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3661, doi. 10.2147/DDDT.S107490
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Study of the antibacterial and antifungal activities of synthetic benzyl bromides, ketones, and corresponding chalcone derivatives.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3653, doi. 10.2147/DDDT.S116312
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Anticonvulsant effects of isomeric nonimidazole histamine H<sub>3</sub> receptor antagonists.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3633, doi. 10.2147/DDDT.S114147
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Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source of Syzygium alternifolium through molecular dynamics and pharmacophore-based screening.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3611, doi. 10.2147/DDDT.S111914
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The aqueous extract of Brucea javanica suppresses cell growth and alleviates tumorigenesis of human lung cancer cells by targeting mutated epidermal growth factor receptor.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3599, doi. 10.2147/DDDT.S117443
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Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3591, doi. 10.2147/DDDT.S114879
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Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffold.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3575, doi. 10.2147/DDDT.S118116
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CORRIGENDUM.
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- Drug Design, Development & Therapy, 2016, v. 10, p. 3573, doi. 10.2147/DDDT.S124104
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- Article