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Interfering RNA with multi-targets for efficient gene suppression in HCC cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3604, doi. 10.3892/ijmm.2018.3557
By:
- Li, Tiejun;
- Zhu, York Yuanyuan;
- Ji, Yi;
- Zhou, Songfeng
Publication type:
Article
A novel psoralen derivative-MPFC enhances melanogenesis via activation of p38 MAPK and PKA signaling pathways in B16 cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3727, doi. 10.3892/ijmm.2018.3529
By:
- Yin, Li;
- Pang, Guangxian;
- Niu, Chao;
- Habasi, Maidina;
- Dou, Jun;
- Aisa, Haji Akber
Publication type:
Article
Anti-inflammatory effects of Passiflora foetida L. in LPS-stimulated RAW264.7 macrophages.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3709, doi. 10.3892/ijmm.2018.3559
By:
- Park, Ji-Won;
- Kwon, Ok-Kyoung;
- Ryu, Hyung Won;
- Paik, Jin-Hyub;
- Paryanto, Imam;
- Yuniato, Prasetyawan;
- Choi, Sangho;
- Oh, Sei-Ryang;
- Ahn, Kyung-Seop
Publication type:
Article
Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3717, doi. 10.3892/ijmm.2018.3558
By:
- Kang, Yun-Mi;
- Chung, Kyung-Sook;
- Kook, In-Hoon;
- Kook, Yoon-Bum;
- Bae, Hyunsu;
- Lee, Minho;
- An, Hyo-Jin
Publication type:
Article
MicroRNA-130a regulates chondrocyte proliferation and alleviates osteoarthritis through PTEN/PI3K/Akt signaling pathway.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3699, doi. 10.3892/ijmm.2018.3551
By:
- Zhang, Yun;
- Xu, Shaochen;
- Huang, Eric;
- Zhou, Haichao;
- Li, Bing;
- Shao, Chenni;
- Yang, Yunfeng
Publication type:
Article
Simvastatin induces apoptosis in PTEN-haploinsufficient lipoma cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3691, doi. 10.3892/ijmm.2018.3568
By:
- Kässner, Franziska;
- Sauer, Tina;
- Penke, Melanie;
- Richter, Sandy;
- Landgraf, Kathrin;
- Körner, Antje;
- Kiess, Wieland;
- Händel, Norman;
- Garten, Antje
Publication type:
Article
Islet-1 promotes the proliferation and invasion, and inhibits the apoptosis of A375 human melanoma cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3680, doi. 10.3892/ijmm.2018.3569
By:
- Zhu, Xiaoling;
- Li, Yuzhen;
- Meng, Qinggang
Publication type:
Article
Incorporation of CD40 ligand enhances the immunogenicity of tumor-associated calcium signal transducer 2 virus-like particles against lung cancer.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3671, doi. 10.3892/ijmm.2018.3570
By:
- Xi, Wang;
- Ke, Dong;
- Min, Long;
- Lin, Wang;
- Jiahui, Zuo;
- Fang, Lin;
- Zhaowei, Gao;
- Zhe, Zhang;
- Xi, Chen;
- Huizhong, Zhang
Publication type:
Article
Novel mutations of the SERPINF1 and FKBP10 genes in Chinese families with autosomal recessive osteogenesis imperfecta.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3662, doi. 10.3892/ijmm.2018.3542
By:
- Zhang, Hao;
- Xu, Yang;
- Yue, Hua;
- Wang, Chun;
- Gu, Jiemei;
- He, Jinwei;
- Fu, Wenzhen;
- Hu, Weiwei;
- Zhang, Zhenlin
Publication type:
Article
Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3653, doi. 10.3892/ijmm.2018.3550
By:
- Zhang, Bingxin;
- Zhao, Zishen;
- Meng, Xiaoyin;
- Chen, Hongguang;
- Fu, Guojun;
- Xie, Keliang
Publication type:
Article
Rhododendron album Blume extract inhibits TNF-α/IFN-γ-induced chemokine production via blockade of NF-κB and JAK/STAT activation in human epidermal keratinocytes.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3642, doi. 10.3892/ijmm.2018.3556
By:
- Park, Ji-Won;
- Lee, Han-Sol;
- Lim, Yourim;
- Paik, Jin-Hyub;
- Kwon, Ok-Kyoung;
- Kim, Jung-Hee;
- Paryanto, Imam;
- Yunianto, Prasetyawan;
- Choi, Sangho;
- Oh, Sei-Ryang;
- Ahn, Kyung-Seop
Publication type:
Article
Low expression of PTEN is essential for maintenance of a malignant state in human gastric adenocarcinoma via upregulation of p-AURKA mediated by activation of AURKA.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3629, doi. 10.3892/ijmm.2018.3544
By:
- Li, Liwei;
- Song, Yue;
- Liu, Qing;
- Liu, Xi;
- Wang, Rui;
- Kang, Chunsheng;
- Zhang, Qingyu
Publication type:
Article
In vivo effects of the NLRP1/NLRP3 inflammasome pathway on latent respiratory virus infection.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3620, doi. 10.3892/ijmm.2018.3521
By:
- Li, Yong-Huai;
- Wei, Xiang;
- Ji, Shuang;
- Gui, Shu-Yu;
- Zhang, Su-Mei
Publication type:
Article
Isolation, culture and biological characteristics of multipotent porcine tendon-derived stem cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3611, doi. 10.3892/ijmm.2018.3545
By:
- Yang, Jinjuan;
- Zhao, Qianjun;
- Wang, Kunfu;
- Ma, Caiyun;
- Liu, Hao;
- Liu, Yingjie;
- Guan, Weijun
Publication type:
Article
Screening pathogenic genes in oral squamous cell carcinoma based on the mRNA expression microarray data.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3597, doi. 10.3892/ijmm.2018.3514
By:
- Ding, Yang;
- Liu, Pengfei;
- Zhang, Shengsheng;
- Tao, Lin;
- Han, Jianmin
Publication type:
Article
Enhanced rapamycin delivery to hemangiomas by lipid polymer nanoparticles coupled with anti-VEGFR antibody.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3586, doi. 10.3892/ijmm.2018.3518
By:
- Li, Haitao;
- Teng, Yunfei;
- Xu, Xia;
- Liu, Jianyong
Publication type:
Article
The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3577, doi. 10.3892/ijmm.2018.3573
By:
- Yu, Yong-Wu;
- Li, Ming-Xu;
- Zhang, Zhi-Yong;
- Yu, Hai
Publication type:
Article
Secoisolariciresinol diglucoside prevents the oxidative stress-induced apoptosis of myocardial cells through activation of the JAK2/STAT3 signaling pathway.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3570, doi. 10.3892/ijmm.2018.3560
By:
- Huang, Guiqiong;
- Huang, Xiaofang;
- Liu, Min;
- Hua, Yue;
- Deng, Bo;
- Jin, Wen;
- Yan, Wen;
- Tan, Zhangbin;
- Wu, Yifen;
- Liu, Bin;
- Zhou, Yingchun
Publication type:
Article
An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-κB and CREB phosphorylation.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3559, doi. 10.3892/ijmm.2018.3546
By:
- Huang, Wen;
- Bai, Shunjie;
- Zuo, Xuzheng;
- Tang, Weiju;
- Chen, Pengfei;
- Chen, Xiuying;
- Wang, Gong;
- Wang, Haoxiang;
- Xie, Peng
Publication type:
Article
Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3551, doi. 10.3892/ijmm.2018.3576
By:
- Wang, Kun;
- Kang, Liang;
- Liu, Wei;
- Song, Yu;
- Wu, Xinghuo;
- Zhang, Yukun;
- Hua, Wenbin;
- Zhao, Kangcheng;
- Li, Shuai;
- Tu, Ji;
- Luo, Rongjin;
- Yang, Cao
Publication type:
Article
Identification of aberrantly expressed long non-coding RNAs in postmenopausal osteoporosis.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3537, doi. 10.3892/ijmm.2018.3575
By:
- Fei, Qi;
- Bai, Xiaodong;
- Lin, Jisheng;
- Meng, Hai;
- Yang, Yong;
- Guo, Ai
Publication type:
Article
Selection of reference genes for expression analysis in mouse models of acute alcoholic liver injury.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3527, doi. 10.3892/ijmm.2018.3527
By:
- Wang, Sheng;
- Wang, Jianqing;
- Lv, Xiongwen
Publication type:
Article
SIRT3 deficiency exacerbates p53/Parkin-mediated mitophagy inhibition and promotes mitochondrial dysfunction: Implication for aged hearts.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3517, doi. 10.3892/ijmm.2018.3555
By:
- Li, Yan;
- Ma, Ying;
- Song, Liqiang;
- Yu, Lu;
- Zhang, Le;
- Zhang, Yingmei;
- Xing, Yuan;
- Yin, Yue;
- Ma, Heng
Publication type:
Article
Cardioprotective effect of rosuvastatin against isoproterenol-induced myocardial infarction injury in rats.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3509, doi. 10.3892/ijmm.2018.3572
By:
- Yu, Ying;
- Jin, Lin;
- Zhuang, Yamin;
- Hu, Yan;
- Cang, Jing;
- Guo, Kefang
Publication type:
Article
CFTR ameliorates high glucose-induced oxidative stress and inflammation by mediating the NF-κB and MAPK signaling pathways in endothelial cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3501, doi. 10.3892/ijmm.2018.3547
By:
- Fei, Yang;
- Sun, Liqin;
- Yuan, Chungang;
- Jiang, Min;
- Lou, Qinhua;
- Xu, Yan
Publication type:
Article
3,5,4'-Tri-O-acetylresveratrol attenuates seawater inhalation-induced acute respiratory distress syndrome via thioredoxin 1 pathway.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3493, doi. 10.3892/ijmm.2018.3528
By:
- Zhao, Yilin;
- Ma, Lijie;
- Wang, Ruixuan;
- Chen, Tingting;
- Liu, Xueying;
- Jin, Faguang
Publication type:
Article
Daidzein exerts anticancer activity towards SKOV3 human ovarian cancer cells by inducing apoptosis and cell cycle arrest, and inhibiting the Raf/MEK/ERK cascade.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3485, doi. 10.3892/ijmm.2018.3531
By:
- Hua, Fu;
- Li, Chang-Hua;
- Chen, Xiao-Gang;
- Liu, Xiao-Ping
Publication type:
Article
Microarray analysis of the expression profile of lncRNAs reveals the key role of lncRNA BC088327 as an agonist to heregulin-1β-induced cell proliferation in peripheral nerve injury.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3477, doi. 10.3892/ijmm.2018.3571
By:
- Wang, Houlei;
- Wu, Jingping;
- Zhang, Xinchao;
- Ding, Lei;
- Zeng, Qingmin
Publication type:
Article
miR-124/MCP-1 signaling pathway modulates the protective effect of itraconazole on acute kidney injury in a mouse model of disseminated candidiasis.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3468, doi. 10.3892/ijmm.2018.3564
By:
- Li, Xiao-Yue;
- Zhang, Yu-Qi;
- Xu, Gang;
- Li, Shao-Hong;
- Li, Heng
Publication type:
Article
Ephrin-B3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine-induced model of epilepsy.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3457, doi. 10.3892/ijmm.2018.3543
By:
- Liu, Tian-Tian;
- Li, Yi;
- Shu, Yi;
- Xiao, Bo;
- Feng, Li
Publication type:
Article
MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3448, doi. 10.3892/ijmm.2018.3539
By:
- Zhuang, Wei;
- Wang, Caiji;
- Shi, Xi;
- Qiu, Shiwei;
- Zhang, Shili;
- Xu, Bing;
- Chen, Min;
- Jiang, Wen;
- Dong, Hongyan;
- Qiao, Yuehua
Publication type:
Article
Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3433, doi. 10.3892/ijmm.2018.3534
By:
- Zhou, Ding;
- Chen, Yi-Xuan;
- Yin, Jun-Hui;
- Tao, Shi-Cong;
- Guo, Shang-Chun;
- Wei, Zhan-Ying;
- Feng, Yong;
- Zhang, Chang-Qing
Publication type:
Article
Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3422, doi. 10.3892/ijmm.2018.3523
By:
- Feng, Chencheng;
- Zhang, Yang;
- Yang, Minghui;
- Lan, Minghong;
- Huang, Bo;
- Liu, Huan;
- Zhou, Yue
Publication type:
Article
Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: Inhibition by ST1926.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3405, doi. 10.3892/ijmm.2018.3574
By:
- Dong, Zewu;
- Yuan, Yufang
Publication type:
Article
PEDF protects cardiomyocytes by promoting FUNDC1-mediated mitophagy via PEDF-R under hypoxic condition.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3394, doi. 10.3892/ijmm.2018.3536
By:
- Li, Yufeng;
- Liu, Zhiwei;
- Zhang, Yiqian;
- Zhao, Qixiang;
- Wang, Xiaoyu;
- Lu, Peng;
- Zhang, Hao;
- Wang, Zhu;
- Dong, Hongyan;
- Zhang, Zhongming
Publication type:
Article
MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3379, doi. 10.3892/ijmm.2018.3526
By:
- Liu, Hongxia;
- Zhong, Liang;
- Yuan, Taixian;
- Chen, Sicheng;
- Zhou, Yiqing;
- An, Liqin;
- Guo, Yangliu;
- Fan, Mengtian;
- Li, Ya;
- Sun, Yanting;
- Li, Wang;
- Shi, Qiong;
- Weng, Yaguang
Publication type:
Article
c-Myc regulates the CDK1/cyclin B1 dependent-G<sub>2</sub>/M cell cycle progression by histone H4 acetylation in Raji cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3366, doi. 10.3892/ijmm.2018.3519
By:
- Yang, Yan;
- Xue, Kai;
- Li, Zhi;
- Zheng, Wei;
- Dong, Weijie;
- Song, Jiazhe;
- Sun, Shijie;
- Ma, Tonghui;
- Li, Wenzhe
Publication type:
Article
Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3353, doi. 10.3892/ijmm.2018.3554
By:
- Dong, Ze-Wu;
- Yuan, Yu-Fang
Publication type:
Article
Overexpression of adrenomedullin protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the Akt/GSK3β and Bcl-2 signaling pathways.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3342, doi. 10.3892/ijmm.2018.3533
By:
- Si, Hongjin;
- Zhang, Yao;
- Song, Yuqing;
- Li, Lili
Publication type:
Article
Transcriptomic and proteomic analysis of potential therapeutic target genes in the liver of metformin-treated Sprague-Dawley rats with type 2 diabetes mellitus.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3327, doi. 10.3892/ijmm.2018.3535
By:
- Chen, Yitao;
- Wu, Yangsheng;
- Yang, Yuanxiao;
- Xu, Zhiwei;
- Tong, Junfeng;
- Li, Zheming;
- Zhou, Xiaojie;
- Li, Changyu
Publication type:
Article
Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3316, doi. 10.3892/ijmm.2018.3522
By:
- Feng, Chencheng;
- Yang, Minghui;
- Zhang, Yang;
- Lan, Minghong;
- Huang, Bo;
- Liu, Huan;
- Zhou, Yue
Publication type:
Article
Effect of electro-acupuncture on the BDNF-TrkB pathway in the spinal cord of CCI rats.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3307, doi. 10.3892/ijmm.2018.3563
By:
- Tu, Wen-Zhan;
- Li, Si-Si;
- Jiang, Xia;
- Qian, Xin-Ru;
- Yang, Guan-Hu;
- Gu, Peng-Peng;
- Lu, Bin;
- Jiang, Song-He
Publication type:
Article
Expression of immunoglobulin G in human podocytes, and its role in cell viability and adhesion.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3296, doi. 10.3892/ijmm.2018.3525
By:
- Jing, Ziyang;
- Deng, Hui;
- Ma, Junfan;
- Guo, Yanhong;
- Liang, Yaoxian;
- Wu, Rui;
- A, Lata;
- Geng, Zihan;
- Qiu, Xiaoyan;
- Wang, Yue
Publication type:
Article
RP105 alleviates myocardial ischemia reperfusion injury via inhibiting TLR4/TRIF signaling pathways.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3287, doi. 10.3892/ijmm.2018.3538
By:
- Yang, Jun;
- Yang, Chaojun;
- Yang, Jian;
- Ding, Jiawang;
- Li, Xinxin;
- Yu, Qinqin;
- Guo, Xin;
- Fan, Zhixing;
- Wang, Huibo
Publication type:
Article
Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl-2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3278, doi. 10.3892/ijmm.2018.3562
By:
- Wang, Baodong;
- Luo, Yankun;
- Zhou, Xiaoshuang;
- Li, Rongshan
Publication type:
Article
Tree shrew neural stem cell transplantation promotes functional recovery of tree shrews with a hemi-sectioned spinal cord injury by upregulating nerve growth factor expression.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3267, doi. 10.3892/ijmm.2018.3553
By:
- Xiong, Liu-Lin;
- Zou, Yu;
- Shi, Yu;
- Zhang, Piao;
- Zhang, Rong-Ping;
- Dai, Xie-Jie;
- Liu, Bin;
- Wang, Ting-Hua
Publication type:
Article
Aspirin modulates the inflammatory response in a thrombus-stimulated LMVEC model.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3253, doi. 10.3892/ijmm.2018.3561
By:
- Wang, Lingcong;
- Ying, Rongbiao;
- Jiang, Huifang;
- Jin, Qun;
- Kuang, Jing;
- Zhang, Zhirong;
- Shi, Ying;
- Cai, Danli;
- Yang, Ruhui
Publication type:
Article
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF-R.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3243, doi. 10.3892/ijmm.2018.3552
By:
- Zhao, Qixiang;
- Liu, Zhiwei;
- Huang, Bing;
- Yuan, Yanliang;
- Liu, Xiucheng;
- Zhang, Hu;
- Qiu, Fan;
- Zhang, Yiqian;
- Li, Yufeng;
- Miao, Haoran;
- Dong, Hongyan;
- Zhang, Zhongming
Publication type:
Article
Mangiferin induces islet regeneration in aged mice through regulating p16<sup>INK4a</sup>.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3231, doi. 10.3892/ijmm.2018.3524
By:
- Wang, Hailian;
- He, Xia;
- Lei, Tiantian;
- Liu, Yilong;
- Huai, Guoli;
- Sun, Minghan;
- Deng, Shaoping;
- Yang, Hongji;
- Tong, Rongsheng;
- Wang, Yi
Publication type:
Article
MicroRNA-30e protects the heart against ischemia and reperfusion injury through autophagy and the Notch1/Hes1/Akt signaling pathway.
Published in:
International Journal of Molecular Medicine, 2018, v. 41, n. 6, p. 3221, doi. 10.3892/ijmm.2018.3548
By:
- Zheng, Jianjie;
- Li, Jing;
- Kou, Bo;
- Yi, Qiuyue;
- Shi, Tao
Publication type:
Article

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