Works matching IS 10966080 AND DT 2020 AND VI 177 AND IP 1

Results: 26

Polyethylene Oxide Molecular Size Determines the Severity of Atypical Thrombotic Microangiopathy in a Guinea Pig Model of Acute Intravenous Exposure.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 235, doi. 10.1093/toxsci/kfaa099
By:
- Baek, Jin Hyen;
- Shin, Hye Kyung H;
- Koo, Soo Min;
- Gao, Yamei;
- Qu, Haiou;
- Feng, Xin;
- Xu, Xiaoming;
- Pinto, Julia;
- Katneni, Upendra;
- Kimchi-Sarfaty, Chava;
- Buehler, Paul W
Publication type:
Article
Inducible and Conditional Stimulation of Adult Hippocampal Neurogenesis Rescues Cadmium-Induced Impairments of Adult Hippocampal Neurogenesis and Hippocampus-Dependent Memory in Mice.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 263, doi. 10.1093/toxsci/kfaa104
By:
- Wang, Hao;
- Matsushita, Megumi T;
- Zhang, Liang;
- Abel, Glen M;
- Mommer, Brett C;
- Huddy, Timothy F;
- Storm, Daniel R;
- Xia, Zhengui
Publication type:
Article
Aneugen Versus Clastogen Evaluation and Oxidative Stress-Related Mode-of-Action Assessment of Genotoxic Compounds Using the ToxTracker Reporter Assay.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 202, doi. 10.1093/toxsci/kfaa103
By:
- Brandsma, Inger;
- Moelijker, Nynke;
- Derr, Remco;
- Hendriks, Giel
Publication type:
Article
Gene Expression Thresholds Derived From Short-term Exposures Identify Rat Liver Tumorigens.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 41, doi. 10.1093/toxsci/kfaa102
By:
- Hill, Thomas;
- Rooney, John;
- Abedini, Jaleh;
- El-Masri, Hisham;
- Wood, Charles E;
- Corton, J Christopher
Publication type:
Article
A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-term Assays.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 11, doi. 10.1093/toxsci/kfaa101
By:
- Corton, J Christopher;
- Hill, Thomas;
- Sutherland, Jeffrey J;
- Stevens, James L;
- Rooney, John
Publication type:
Article
Drp-1-Dependent Mitochondrial Fragmentation Contributes to Cobalt Chloride-Induced Toxicity in Caenorhabditis elegans.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 158, doi. 10.1093/toxsci/kfaa105
By:
- Zheng, Fuli;
- Chen, Pan;
- Li, Huangyuan;
- Aschner, Michael
Publication type:
Article
Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Acute Myeloid Leukemia.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 94, doi. 10.1093/toxsci/kfaa098
By:
- Karbowski, Christine;
- Goldstein, Rebecca;
- Frank, Brendon;
- Kim, Kei;
- Li, Chi-Ming;
- Homann, Oliver;
- Hensley, Kelly;
- Brooks, Benjamin;
- Wang, Xiaoting;
- Yan, Qinghong;
- Hernandez, Rocio;
- Adams, Gregor;
- Boyle, Michael;
- Arvedson, Tara;
- Lebrec, Herve
Publication type:
Article
A Novel Sox9/lncRNA H19 Axis Contributes to Hepatocyte Death and Liver Fibrosis.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 214, doi. 10.1093/toxsci/kfaa097
By:
- Wang, Chenqi;
- Deng, Jia;
- Deng, Hao;
- Kang, Zhiqian;
- Huang, Zhen;
- Ding, Zhi;
- Dong, Lei;
- Chen, Jiangning;
- Zhang, Junfeng;
- Zang, Yuhui
Publication type:
Article
Bridging the Gap Between Alleged Toxicity and Forcing Chemical Regulation: Science Transparency Demands a Specialized Interagency Peer Review Panel for Chemical Epidemiology.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 156, doi. 10.1093/toxsci/kfaa096
By:
- Doherty, John D
Publication type:
Article
Broad Spectrum Treatment for Ocular Insult Induced by Organophosphate Chemical Warfare Agents.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 1, doi. 10.1093/toxsci/kfaa095
By:
- Gore, Ariel
Publication type:
Article
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 121, doi. 10.1093/toxsci/kfaa094
By:
- Kang, Wen;
- Podtelezhnikov, Alexei A;
- Tanis, Keith Q;
- Pacchione, Stephen;
- Su, Ming;
- Bleicher, Kimberly B;
- Wang, Zhibin;
- Laws, George M;
- Griffiths, Thomas G;
- Kuhls, Matthew C;
- Chen, Qing;
- Knemeyer, Ian;
- Marsh, Donald J;
- Mitra, Kaushik;
- Lebron, Jose;
- Sistare, Frank D
Publication type:
Article
Mechanistic Investigations Support Liver Safety of Ubrogepant.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 84, doi. 10.1093/toxsci/kfaa093
By:
- Smith, Brenda;
- Rowe, Josh;
- Watkins, Paul B;
- Ashina, Messoud;
- Woodhead, Jeffrey L;
- Sistare, Frank D;
- Goadsby, Peter J
Publication type:
Article
Phenotypic Characterization of Targeted Knockdown of Cyclin-Dependent Kinases in the Intestinal Epithelial Cells.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 226, doi. 10.1093/toxsci/kfaa092
By:
- Lu, Shuyan;
- Sung, Tae;
- Amaro, Marina;
- Hirakawa, Brad;
- Jessen, Bart;
- Hu, Wenyue
Publication type:
Article
The UVR Filter Octinoxate Modulates Aryl Hydrocarbon Receptor Signaling in Keratinocytes via Inhibition of CYP1A1 and CYP1B1.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 188, doi. 10.1093/toxsci/kfaa091
By:
- Phelan-Dickinson, Sarah J;
- Palmer, Brian C;
- Chen, Yue;
- DeLouise, Lisa A
Publication type:
Article
Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 168, doi. 10.1093/toxsci/kfaa090
By:
- Lim, Joe Jongpyo;
- Li, Xueshu;
- Lehmler, Hans-Joachim;
- Wang, Dongfang;
- Gu, Haiwei;
- Cui, Julia Yue
Publication type:
Article
Induction of Oxidative DNA Damage and Epithelial Mesenchymal Transitions in Small Airway Epithelial Cells Exposed to Cosmetic Aerosols.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 248, doi. 10.1093/toxsci/kfaa089
By:
- Pearce, Kaitlin M;
- Okon, Imoh;
- Watson-Wright, Christa
Publication type:
Article
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 281, doi. 10.1093/toxsci/kfaa088
By:
- Monroe, James J;
- Tanis, Keith Q;
- Podtelezhnikov, Alexei A;
- Nguyen, Truyen;
- Machotka, Sam V;
- Lynch, Donna;
- Evers, Raymond;
- Palamanda, Jairam;
- Miller, Randy R;
- Pippert, Todd;
- Cabalu, Tamara D;
- Johnson, Timothy E;
- Aslamkhan, Amy G;
- Kang, Wen;
- Tamburino, Alex M;
- Mitra, Kaushik;
- Agrawal, Nancy G B;
- Sistare, Frank D
Publication type:
Article
Effects of Arsenic (+3 Oxidation State) Methyltransferase Gene Polymorphisms and Expression on Bladder Cancer: Evidence from a Systematic Review, Meta-analysis and TCGA Dataset.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 27, doi. 10.1093/toxsci/kfaa087
By:
- Song, Yuxuan;
- Jin, Donghui;
- Chen, Jingyi;
- Liang, Wanfeng;
- Liu, Xiaoqiang
Publication type:
Article
A Positive Feedback Loop Between c-Myc Upregulation, Glycolytic Shift, and Histone Acetylation Enhances Cancer Stem Cell-like Property and Tumorigenicity of Cr(VI)-transformed Cells.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 71, doi. 10.1093/toxsci/kfaa086
By:
- Clementino, Marco;
- Xie, Jie;
- Yang, Ping;
- Li, Yunfei;
- Lin, Hsuan-Pei;
- Fenske, William K;
- Tao, Hua;
- Kondo, Kazuya;
- Yang, Chengfeng;
- Wang, Zhishan
Publication type:
Article
Exposure Effects Beyond the Epithelial Barrier: Transepithelial Induction of Oxidative Stress by Diesel Exhaust Particulates in Lung Fibroblasts in an Organotypic Human Airway Model.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 140, doi. 10.1093/toxsci/kfaa085
By:
- Faber, Samantha C;
- McNabb, Nicole A;
- Ariel, Pablo;
- Aungst, Emily R;
- McCullough, Shaun D
Publication type:
Article
Bioactivity of Circulatory Factors After Pulmonary Exposure to Mild or Stainless Steel Welding Fumes.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 108, doi. 10.1093/toxsci/kfaa084
By:
- Kodali, Vamsi;
- Shoeb, Mohammad;
- Meighan, Terence G;
- Eye, Tracy;
- Friend, Sherri A;
- Hubczak, John;
- Kashon, Michael L;
- Zeidler-Erdely, Patti C;
- Antonini, James M;
- Erdely, Aaron
Publication type:
Article
Erratum to: "Low Dose of Bisphenol A. Modulates Ovarian Cancer Gene Expression Profile and Promotes Epithelial to Mesenchymal Transition Via Canonical Wnt Pathway".
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 303, doi. 10.1093/toxsci/kfaa083
By:
- Lin, Hui;
- Li, Hongyi;
- Lu, Guang;
- Chen, Zhifeng;
- Sun, Wenjie;
- Shi, Yu;
- Fu, Zhiqin;
- Huang, Bo;
- Zhu, Xinqiang;
- Lu, Weiguo;
- Xia, Dajing;
- Wu, Yihua
Publication type:
Article
The Relationship Between Internal and External Dose: Some General Results Based on a Generic Compartmental Model.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 60, doi. 10.1093/toxsci/kfaa082
By:
- Slob, Wout;
- Zeilmaker, Marco J;
- Hoogenveen, Rudolf T
Publication type:
Article
Corrigendum to: "Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity".
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 301, doi. 10.1093/toxsci/kfaa064
By:
- Zurlinden, Todd J;
- Saili, Katerine S;
- Rush, Nathaniel;
- Kothiya, Parth;
- Judson, Richard S;
- Houck, Keith A;
- Hunter, E Sidney;
- Baker, Nancy C;
- Palmer, Jessica A;
- Thomas, Russell S;
- Knudsen, Thomas B
Publication type:
Article
Corrigendum to: "A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin".
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 300, doi. 10.1093/toxsci/kfaa057
By:
- McGarry, Kevin G;
- Lalisse, Remy F;
- Moyer, Robert A;
- Johnson, Kristyn M;
- Tallan, Alexi M;
- Winters, Tyson P;
- Taris, Joseph E;
- McElroy, Craig A;
- Lemmon, Erin E;
- Shafaat, Hannah S;
- Fan, Yamin;
- Deal, Aniliese;
- Marguet, Sean C;
- Harvilchuck, Jill A;
- Hadad, Christopher M;
- Wood, David W
Publication type:
Article
Erratum to: "Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling and Computational Systems Biology".
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 302, doi. 10.1093/toxsci/kfaa038
By:
- Ruiz, Patricia;
- Emond, Claude;
- McLanahan, Eva D;
- Joshi-Barr, Shivanjali;
- Mumtaz, Moiz
Publication type:
Article