Works in Toxicological Sciences, 2017, Vol 155, Issue 1

Results: 29

Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 270, doi. 10.1093/toxsci/kfw209

By:

Marchitti, Satori A.;
Mazur, Christopher S.;
Dillingham, Caleb M.;
Rawat, Swati;
Sharma, Anshika;
Zastre, Jason;
Kenneke, John F.

Publication type:

Article

Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure?

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 75, doi. 10.1093/toxsci/kfw180

By:

Slotkin, Theodore A.;
Stadler, Ashley;
Skavicus, Samantha;
Card, Jennifer;
Ruff, Jonathan;
Levin, Edward D.;
Seidler, Frederic J.

Publication type:

Article

The Lack of Mutagenic Potential of a Guanine-Rich Triplex Forming Oligonucleotide in Physiological Conditions.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 101, doi. 10.1093/toxsci/kfw179

By:

Saleh, Amer F.;
Fellows, Mick D.;
Liming Ying;
Gooderham, Nigel J.;
Priestley, Catherine C.

Publication type:

Article

Vulnerability of C6 Astrocytoma Cells After Single-Compound and Joint Exposure to Type I and Type II Pyrethroid Insecticides.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 196, doi. 10.1093/toxsci/kfw188

By:

Romero, Delfina M.;
Berardino, Bruno G.;
Wolansky, Marcelo J.;
Kotler, Mónica L.

Publication type:

Article

Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 248, doi. 10.1093/toxsci/kfw198

By:

Moses, Elizabeth;
Wang, Teresa;
Corbett, Sean;
Jackson, George R.;
Drizik, Eduard;
Perdomo, Catalina;
Perdomo, Claudia;
Kleerup, Eric;
Brooks, Daniel;
O'Connor, George;
Dubinett, Steven;
Hayden, Patrick;
Lenburg, Marc E.;
Spira, Avrum

Publication type:

Article

Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 258, doi. 10.1093/toxsci/kfw210

By:

Zhifeng Xu;
Qiong Wu;
Qiang Xu;
Lin He

Publication type:

Article

Calcium-Sensing Receptor and Transient Receptor Ankyrin-1 Mediate Emesis Induction by Deoxynivalenol (Vomitoxin).

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 32, doi. 10.1093/toxsci/kfw191

By:

Wenda Wu;
Hui-Ren Zhou;
Bursian, Steven J.;
Link, Jane E.;
Pestka, James J.

Publication type:

Article

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 61, doi. 10.1093/toxsci/kfw193

By:

Woodhead, Jeffrey L.;
Brock, William J.;
Roth, Sharin E.;
Shoaf, Susan E.;
Brouwer, Kim L. R.;
Church, Rachel;
Grammatopoulos, Tom N.;
Stiles, Linsey;
Siler, Scott Q.;
Howell, Brett A.;
Mosedale, Merrie;
Watkins, Paul B.;
Shoda, Lisl K. M.

Publication type:

Article

Comparative Renal Safety Assessment of the Hepatitis B Drugs, Adefovir, Tenofovir, Telbivudine and Entecavir in Rats.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 283, doi. 10.1093/toxsci/kfw208

By:

Uteng, Marianne;
Mahl, Andreas;
Beckmann, Nicolau;
Piaia, Alessandro;
Ledieu, David;
Dubost, Valerie;
Tritto, Elaine;
Wolf, Armin;
Moulin, Pierre;
Li Li;
Chibout, Salah-Dine;
Pognan, Francois

Publication type:

Article

Comparative renal toxicity of hepatitis B drugs.

Published in:

2017

By:

Lu Cai

Publication type:

Abstract

Spleen-derived macrophages following ozone.

Published in:

2017

By:

Campen, Matthew J.

Publication type:

Abstract

Short-term studies may help identify chemicals with low cancer risk.

Published in:

2017

By:

Johanson, Gunnar

Publication type:

Abstract

Screening toxcast prioritized chemicals for PPARγ function in a human-derived stem cell model of adipogenesis.

Published in:

2017

By:

Peters, Jeffrey M.

Publication type:

Abstract

Mechanistic Evaluation of Benzo[a]pyrene's Developmental Toxicities Mediated by Reduced Cyp19a1b Activity.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 135, doi. 10.1093/toxsci/kfw182

By:

Alharthy, Khalid M.;
Albaqami, Faisal F.;
Thornton, Cammi;
Corrales, Jone;
Willett, Kristine L.

Publication type:

Article

From the Editor's Desk.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 1, doi. 10.1093/toxsci/kfw232

By:

Miller, Gary W.

Publication type:

Article

High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial Cells.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 43, doi. 10.1093/toxsci/kfw178

By:

Shenxuan Liang;
Lei Yin;
Kevin Shengyang Yu;
Hofmann, Marie-Claude;
Xiaozhong Yu

Publication type:

Article

FutureTox III: Bridges for Translation.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 22, doi. 10.1093/toxsci/kfw194

By:

Juberg, Daland R.;
Knudsen, Thomas B.;
Sander, Miriam;
Beck, Nancy B.;
Faustman, Elaine M.;
Mendrick, Donna L.;
Fowle III, John R.;
Hartung, Thomas;
Tice, Raymond R.;
Lemazurier, Emmanuel;
Becker, Richard A.;
Fitzpatrick, Suzanne Compton;
Daston, George P.;
Harrill, Alison;
Hines, Ronald N.;
Keller, Douglas A.;
Lipscomb, John C.;
Watson, David;
Bahadori, Tina;
Crofton, Kevin M.

Publication type:

Article

Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 112, doi. 10.1093/toxsci/kfw187

By:

Hossain, Muhammad M.;
Jason Liu;
Richardson, Jason R.

Publication type:

Article

An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 170, doi. 10.1093/toxsci/kfw189

By:

Holland, Erika B.;
Wei Feng;
Jing Zheng;
Yao Dong;
Xueshu Li;
Lehmler, Hans-Joachim;
Pessah, Isaac N.

Publication type:

Article

Negative Predictors of Carcinogenicity for Environmental Chemicals.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 157, doi. 10.1093/toxsci/kfw195

By:

Hill III, Thomas;
Nelms, Mark D.;
Edwards, Stephen W.;
Martin, Matthew;
Judson, Richard;
Corton, J. Christopher;
Wood, Charles E.

Publication type:

Article

Role of Spleen-Derived Macrophages in Ozone-Induced Lung Inflammation and Injury.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 182, doi. 10.1093/toxsci/kfw192

By:

Francis, Mary;
Sun, Richard;
Cervelli, Jessica A.;
Hyejeong Choi;
Mandal, Mili;
Abramova, Elena V.;
Gow, Andrew J.;
Laskin, Jeffrey D.;
Laskin, Debra L.

Publication type:

Article

Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 85, doi. 10.1093/toxsci/kfw186

By:

Foley, Briana;
Doheny, Daniel L.;
Black, Michael B.;
Pendse, Salil N.;
Wetmore, Barbara A.;
Clewell, Rebecca A.;
Andersen, Melvin E.;
Deisenroth, Chad

Publication type:

Article

Manganese Stimulates Mitochondrial H<sub>2</sub>O<sub>2</sub> Production in SH-SY5Y Human Neuroblastoma Cells Over Physiologic as well as Toxicologic Range.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 213, doi. 10.1093/toxsci/kfw196

By:

Fernandes, Jolyn;
Li Hao;
Bijli, Kaiser M.;
Chandler, Joshua D.;
Orr, Michael;
Xin Hu;
Jones, Dean P.;
Young-Mi Go

Publication type:

Article

Role of Mitochondrial Toxicity in BMS-986094-Induced Toxicity.

Published in:

2017

By:

Feng, Joy Y.;
Tay, Chin H.;
Ray, Adrian S.

Publication type:

Letter to the Editor

Long Non-Coding RNAs: A Novel Paradigm for Toxicology.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 3, doi. 10.1093/toxsci/kfw203

By:

Dempsey, Joseph L.;
Julia Yue Cui

Publication type:

Article

PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr51 Stem Cells.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 224, doi. 10.1093/toxsci/kfw190

By:

Chen, Jayson X.;
Hong Wang;
Anna Liu;
Lanjing Zhang;
Reuhl, Kenneth;
Yang, Chung S.

Publication type:

Article

Interactive Influence of N6AMT1 and As3MT Genetic Variations on Arsenic Metabolism in the Population of Inner Mongolia, China.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 124, doi. 10.1093/toxsci/kfw181

By:

Xushen Chen;
Xiaojuan Guo;
Ping He;
Jing Nie;
Xiaoyan Yan;
Jinqiu Zhu;
Luoping Zhang;
Guangyun Mao;
Hongmei Wu;
Zhiyue Liu;
Aga, Diana;
Peilin Xu;
Smith, Martyn;
Xuefeng Ren

Publication type:

Article

Effects of the Janus Kinase Inhibitor, Tofacitinib, on Testicular Leydig Cell Hyperplasia and Adenoma in Rats, and on Prolactin Signaling in Cultured Primary Rat Leydig Cells.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 148, doi. 10.1093/toxsci/kfw197

By:

Chapin, Robert E.;
Ball, Douglas J.;
Radi, Zaher A.;
Kumpf, Steven W.;
Koza-Taylor, Petra H.;
Potter, David M.;
Vogel, W. Mark

Publication type:

Article

Comprehensive Translational Assessment of Human- Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 234, doi. 10.1093/toxsci/kfw200

By:

Blinova, Ksenia;
Stohlman, Jayna;
Vicente, Jose;
Chan, Dulciana;
Johannesen, Lars;
Hortigon-Vinagre, Maria P.;
Zamora, Victor;
Smith, Godfrey;
Crumb, William J.;
Li Pang;
Lyn-Cook, Beverly;
Ross, James;
Brock, Mathew;
Chvatal, Stacie;
Millard, Daniel;
Galeotti, Loriano;
Stockbridge, Norman;
Strauss, David G.

Publication type:

Article