Works matching IS 10788956 AND DT 2015 AND VI 21 AND IP 4

Results: 30

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 383, doi. 10.1038/nm.3820

By:

Wang, Peng;
Alvarez-Perez, Juan-Carlos;
Felsenfeld, Dan P;
Liu, Hongtao;
Sivendran, Sharmila;
Bender, Aaron;
Kumar, Anil;
Sanchez, Roberto;
Scott, Donald K;
Garcia-Ocaña, Adolfo;
Stewart, Andrew F

Publication type:

Article

Warren joins lawmakers proposing new ideas for science funding.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 299, doi. 10.1038/nm0415-299

By:

Dove, Alan

Publication type:

Article

Reexamination casts doubt on brain tissue classified as healthy.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 296, doi. 10.1038/nm0415-296

By:

Chakradhar, Shraddha

Publication type:

Article

Biomedical briefing.

Published in:: Nature Medicine, 2015, v. 21, n. 4, p. 302, doi. 10.1038/nm0415-302
Publication type:: Article

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 335, doi. 10.1038/nm.3832

By:

Chen, Chun-Wei;
Koche, Richard P;
Sinha, Amit U;
Deshpande, Aniruddha J;
Zhu, Nan;
Eng, Rowena;
Doench, John G;
Xu, Haiming;
Chu, Scott H;
Qi, Jun;
Wang, Xi;
Delaney, Christopher;
Bernt, Kathrin M;
Root, David E;
Hahn, William C;
Bradner, James E;
Armstrong, Scott A

Publication type:

Article

Intracellular chloride accumulation: a possible mechanism for cognitive deficits in Down syndrome.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 312, doi. 10.1038/nm.3836

By:

Costa, Alberto C

Publication type:

Article

Questions raised about whether compulsory licenses get best prices.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 300, doi. 10.1038/nm0415-300

By:

Owens, Brian

Publication type:

Article

Many returns: Call-ins and breakfasts hand back results to study volunteers.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 304, doi. 10.1038/nm0415-304

By:

Chakradhar, Shraddha

Publication type:

Article

Erratum: A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.

Published in:: Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414e
Publication type:: Article

New model tackles sticky problem of getting drugs past mucus.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 301, doi. 10.1038/nm0415-301

By:

Bhatia, Juhie

Publication type:

Article

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 314, doi. 10.1038/nm.3812

By:

Goel, Suchi;
Palmkvist, Mia;
Moll, Kirsten;
Joannin, Nicolas;
Lara, Patricia;
R Akhouri, Reetesh;
Moradi, Nasim;
Öjemalm, Karin;
Westman, Mattias;
Angeletti, Davide;
Kjellin, Hanna;
Lehtiö, Janne;
Blixt, Ola;
Ideström, Lars;
Gahmberg, Carl G;
Storry, Jill R;
Hult, Annika K;
Olsson, Martin L;
von Heijne, Gunnar;
Nilsson, IngMarie

Publication type:

Article

Corrigendum: Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414b

By:

Wein, Nicolas;
Vulin, Adeline;
Falzarano, Maria S;
Szigyarto, Christina Al-Khalili;
Maiti, Baijayanta;
Findlay, Andrew;
Heller, Kristin N;
Uhlén, Mathias;
Bakthavachalu, Baskar;
Messina, Sonia;
Vita, Giuseppe;
Passarelli, Chiara;
Gualandi, Francesca;
Wilton, Steve D;
Rodino-Klapac, Louise R;
Yang, Lin;
Dunn, Diane M;
Schoenberg, Daniel R;
Weiss, Robert B;
Howard, Michael T

Publication type:

Article

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 373, doi. 10.1038/nm.3826

By:

Wu, Yue;
Song, Ping;
Zhang, Wencheng;
Liu, Junhui;
Dai, Xiaoyan;
Liu, Zhaoyu;
Lu, Qiulun;
Ouyang, Changhan;
Xie, Zhonglin;
Zhao, Zhengxing;
Zhuo, Xiaozhen;
Viollet, Benoit;
Foretz, Marc;
Wu, Jiliang;
Yuan, Zuyi;
Zou, Ming-Hui

Publication type:

Article

Corrigendum: Inhibition of JAK-STAT signaling stimulates adult satellite cell function.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414a

By:

Price, Feodor D;
von Maltzahn, Julia;
Bentzinger, C Florian;
Dumont, Nicolas A;
Yin, Hang;
Chang, Natasha C;
Wilson, David H;
Frenette, Jérôme;
Rudnicki, Michael A

Publication type:

Article

Reversing excitatory GABA<sub>A</sub>R signaling restores synaptic plasticity and memory in a mouse model of Down syndrome.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 318, doi. 10.1038/nm.3827

By:

Deidda, Gabriele;
Parrini, Martina;
Naskar, Shovan;
Bozarth, Ignacio F;
Contestabile, Andrea;
Cancedda, Laura

Publication type:

Article

Genetic and functional characterization of clonally derived adult human brown adipocytes.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 389, doi. 10.1038/nm.3819

By:

Shinoda, Kosaku;
Luijten, Ineke H N;
Hasegawa, Yutaka;
Hong, Haemin;
Sonne, Si B;
Kim, Miae;
Xue, Ruidan;
Chondronikola, Maria;
Cypess, Aaron M;
Tseng, Yu-Hua;
Nedergaard, Jan;
Sidossis, Labros S;
Kajimura, Shingo

Publication type:

Article

A mediator for malaria stickiness in A versus O blood.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 307, doi. 10.1038/nm.3837

By:

Mancio-Silva, Liliana;
Mota, Maria M

Publication type:

Article

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 407, doi. 10.1038/nm.3807

By:

Guo, Tiannan;
Kouvonen, Petri;
Koh, Ching Chiek;
Gillet, Ludovic C;
Wolski, Witold E;
Röst, Hannes L;
Rosenberger, George;
Collins, Ben C;
Blum, Lorenz C;
Gillessen, Silke;
Joerger, Markus;
Jochum, Wolfram;
Aebersold, Ruedi

Publication type:

Article

Germline editing: time for discussion.

Published in:: Nature Medicine, 2015, v. 21, n. 4, p. 295, doi. 10.1038/nm.3845
Publication type:: Article

Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs?

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 310, doi. 10.1038/nm.3835

By:

Wollheim, Claes B;
Maechler, Pierre

Publication type:

Article

Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 353, doi. 10.1038/nm.3816

By:

Lörchner, Holger;
Pöling, Jochen;
Gajawada, Praveen;
Hou, Yunlong;
Polyakova, Viktoria;
Kostin, Sawa;
Adrian-Segarra, Juan M;
Boettger, Thomas;
Wietelmann, Astrid;
Warnecke, Henning;
Richter, Manfred;
Kubin, Thomas;
Braun, Thomas

Publication type:

Article

Corrigendum: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414c

By:

de la Croix Ndong, Jean;
Makowski, Alexander J;
Uppuganti, Sasidhar;
Vignaux, Guillaume;
Ono, Koichiro;
Perrien, Daniel S;
Joubert, Simon;
Baglio, Serena R;
Granchi, Donatella;
Stevenson, David A;
Rios, Jonathan J;
Nyman, Jeffry S;
Elefteriou, Florent

Publication type:

Article

Harnessing gene repression to inhibit leukemia.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 308, doi. 10.1038/nm.3834

By:

Harte, Peter J;
Ernst, Patricia

Publication type:

Article

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 363, doi. 10.1038/nm.3822

By:

Marquard, Jan;
Otter, Silke;
Welters, Alena;
Stirban, Alin;
Fischer, Annelie;
Eglinger, Jan;
Herebian, Diran;
Kletke, Olaf;
Klemen, Maša Skelin;
Stožer, Andraž;
Wnendt, Stephan;
Piemonti, Lorenzo;
Köhler, Martin;
Ferrer, Jorge;
Thorens, Bernard;
Schliess, Freimut;
Rupnik, Marjan Slak;
Heise, Tim;
Berggren, Per-Olof;
Klöcker, Nikolaj

Publication type:

Article

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 401, doi. 10.1038/nm.3813

By:

Dey, Bappaditya;
Dey, Ruchi Jain;
Cheung, Laurene S;
Pokkali, Supriya;
Guo, Haidan;
Lee, Jong-Hee;
Bishai, William R

Publication type:

Article

Targeting the MLL complex in castration-resistant prostate cancer.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 344, doi. 10.1038/nm.3830

By:

Malik, Rohit;
Khan, Amjad P;
Asangani, Irfan A;
Cieślik, Marcin;
Prensner, John R;
Wang, Xiaoju;
Iyer, Matthew K;
Jiang, Xia;
Borkin, Dmitry;
Escara-Wilke, June;
Stender, Rachell;
Wu, Yi-Mi;
Niknafs, Yashar S;
Jing, Xiaojun;
Qiao, Yuanyuan;
Palanisamy, Nallasivam;
Kunju, Lakshmi P;
Krishnamurthy, Pranathi M;
Yocum, Anastasia K;
Mellacheruvu, Dattatreya

Publication type:

Article

Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 395, doi. 10.1038/nm.3824

By:

Lim, Jae Seok;
Kim, Woo-il;
Kang, Hoon-Chul;
Kim, Se Hoon;
Park, Ah Hyung;
Park, Eun Kyung;
Cho, Young-Wook;
Kim, Sangwoo;
Kim, Ho Min;
Kim, Jeong A;
Kim, Junho;
Rhee, Hwanseok;
Kang, Seok-Gu;
Kim, Heung Dong;
Kim, Daesoo;
Kim, Dong-Seok;
Lee, Jeong Ho

Publication type:

Article

After flu vaccine mismatch, calls for delayed selection intensify.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 297, doi. 10.1038/nm0415-297

By:

Marill, Michele Cohen

Publication type:

Article

Erratum: De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414d

By:

Berod, Luciana;
Friedrich, Christin;
Nandan, Amrita;
Freitag, Jenny;
Hagemann, Stefanie;
Harmrolfs, Kirsten;
Sandouk, Aline;
Hesse, Christina;
Castro, Carla N;
Bähre, Heike;
Tschirner, Sarah K;
Gorinski, Nataliya;
Gohmert, Melanie;
Mayer, Christian T;
Huehn, Jochen;
Ponimaskin, Evgeni;
Abraham, Wolf-Rainer;
Müller, Rolf;
Lochner, Matthias;
Sparwasser, Tim

Publication type:

Article

Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 327, doi. 10.1038/nm.3831

By:

Chen, Jonathan H;
Perry, Curtis J;
Tsui, Yao-Chen;
Staron, Matthew M;
Parish, Ian A;
Dominguez, Claudia X;
Rosenberg, Daniel W;
Kaech, Susan M

Publication type:

Article