Works matching IS 10788956 AND DT 2014 AND VI 20 AND IP 12

Results: 31

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1417, doi. 10.1038/nm.3705

By:

Hasnain, Sumaira Z;
Borg, Danielle J;
Harcourt, Brooke E;
Tong, Hui;
Sheng, Yonghua H;
Ng, Choa Ping;
Das, Indrajit;
Wang, Ran;
Chen, Alice C-H;
Loudovaris, Thomas;
Kay, Thomas W;
Thomas, Helen E;
Whitehead, Jonathan P;
Forbes, Josephine M;
Prins, Johannes B;
McGuckin, Michael A

Publication type:

Article

Reply to IL-18 is not therapeutic for neovascular age-related macular degeneration.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1376, doi. 10.1038/nm.3741

By:

Doyle, Sarah L;
Adamson, Peter;
López, Francisco J;
Humphries, Peter;
Campbell, Matthew

Publication type:

Article

Biomedical briefing.

Published in:: Nature Medicine, 2014, v. 20, n. 12, p. 1360, doi. 10.1038/nm1214-1360
Publication type:: Article

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1410, doi. 10.1038/nm.3746

By:

Schubert, Desirée;
Bode, Claudia;
Kenefeck, Rupert;
Hou, Tie Zheng;
Wing, James B;
Kennedy, Alan;
Bulashevska, Alla;
Petersen, Britt-Sabina;
Schäffer, Alejandro A;
Grüning, Björn A;
Unger, Susanne;
Frede, Natalie;
Baumann, Ulrich;
Witte, Torsten;
Schmidt, Reinhold E;
Dueckers, Gregor;
Niehues, Tim;
Seneviratne, Suranjith;
Kanariou, Maria;
Speckmann, Carsten

Publication type:

Article

IL-18 is not therapeutic for neovascular age-related macular degeneration.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1372, doi. 10.1038/nm.3671

By:

Hirano, Yoshio;
Yasuma, Tetsuhiro;
Mizutani, Takeshi;
Fowler, Benjamin J;
Tarallo, Valeria;
Yasuma, Reo;
Kim, Younghee;
Bastos-Carvalho, Ana;
Kerur, Nagaraj;
Gelfand, Bradley D;
Bogdanovich, Sasha;
He, Shikun;
Zhang, Xiaohui;
Nozaki, Miho;
Ijima, Ryo;
Kaneko, Hiroki;
Ogura, Yuichiro;
Terasaki, Hiroko;
Nagai, Hiroshi;
Haro, Isao

Publication type:

Article

2014 in Review.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1366, doi. 10.1038/nm1214-1366

By:

Vaidya, Manasi;
Chakradhar, Shraddha

Publication type:

Article

The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1436, doi. 10.1038/nm.3713

By:

Wang, Guo-Xiao;
Zhao, Xu-Yun;
Meng, Zhuo-Xian;
Kern, Matthias;
Dietrich, Arne;
Chen, Zhimin;
Cozacov, Zoharit;
Zhou, Dequan;
Okunade, Adewole L;
Su, Xiong;
Li, Siming;
Blüher, Matthias;
Lin, Jiandie D

Publication type:

Article

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1452, doi. 10.1038/nm.3736

By:

Wetzel-Smith, Monica K;
Hunkapiller, Julie;
Bhangale, Tushar R;
Srinivasan, Karpagam;
Maloney, Janice A;
Atwal, Jasvinder K;
Sa, Susan M;
B Yaylaoglu, Murat;
Foreman, Oded;
Ortmann, Ward;
Rathore, Nisha;
Hansen, David V;
Tessier-Lavigne, Marc;
Mayeux, Richard;
Pericak-Vance, Margaret;
Haines, Jonathan;
Farrer, Lindsay A;
Schellenberg, Gerard D;
Goate, Alison;
Behrens, Timothy W

Publication type:

Article

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1464, doi. 10.1038/nm.3703

By:

Kikuchi, Ryosuke;
Nakamura, Kazuto;
MacLauchlan, Susan;
Ngo, Doan Thi-Minh;
Shimizu, Ippei;
Fuster, Jose Javier;
Katanasaka, Yasufumi;
Yoshida, Sumiko;
Qiu, Yan;
Yamaguchi, Terry P;
Matsushita, Tadashi;
Murohara, Toyoaki;
Gokce, Noyan;
Bates, David O;
Hamburg, Naomi M;
Walsh, Kenneth

Publication type:

Article

Anchored multiplex PCR for targeted next-generation sequencing.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1479, doi. 10.1038/nm.3729

By:

Zheng, Zongli;
Liebers, Matthew;
Zhelyazkova, Boryana;
Cao, Yi;
Panditi, Divya;
Lynch, Kerry D;
Chen, Juxiang;
Robinson, Hayley E;
Shim, Hyo Sup;
Chmielecki, Juliann;
Pao, William;
Engelman, Jeffrey A;
Iafrate, A John;
Le, Long Phi

Publication type:

Article

MicroRNA-124 modulates social behavior in frontotemporal dementia.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1381, doi. 10.1038/nm.3768

By:

Arrant, Andrew E;
Roberson, Erik D

Publication type:

Article

An emerging consensus on cardiac regeneration.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1386, doi. 10.1038/nm.3764

By:

van Berlo, Jop H;
Molkentin, Jeffery D

Publication type:

Article

Advances in marmoset and mouse models buoy Ebola research.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1356, doi. 10.1038/nm1214-1356

By:

Willyard, Cassandra

Publication type:

Article

Targeting α<sub>4</sub>β<sub>7</sub> integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1397, doi. 10.1038/nm.3715

By:

Byrareddy, Siddappa N;
Kallam, Brianne;
Arthos, James;
Cicala, Claudia;
Nawaz, Fatima;
Hiatt, Joseph;
Kersh, Ellen N;
McNicholl, Janet M;
Hanson, Debra;
Reimann, Keith A;
Brameier, Markus;
Walter, Lutz;
Rogers, Kenneth;
Mayne, Ann E;
Dunbar, Paul;
Villinger, Tara;
Little, Dawn;
Parslow, Tristram G;
Santangelo, Philip J;
Villinger, Francois

Publication type:

Article

Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1401, doi. 10.1038/nm.3740

By:

Baumann, Ursula;
Fernández-Sáiz, Vanesa;
Rudelius, Martina;
Lemeer, Simone;
Rad, Roland;
Knorn, Anna-Maria;
Slawska, Jolanta;
Engel, Katharina;
Jeremias, Irmela;
Li, Zhoulei;
Tomiatti, Viktoriya;
Illert, Anna-Lena;
Targosz, Bianca-Sabrina;
Braun, Martin;
Perner, Sven;
Leitges, Michael;
Klapper, Wolfram;
Dreyling, Martin;
Miething, Cornelius;
Lenz, Georg

Publication type:

Article

An epigenetic therapy for diffuse intrinsic pontine gliomas.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1378, doi. 10.1038/nm.3769

By:

Ramaswamy, Vijay;
Remke, Marc;
Taylor, Michael D

Publication type:

Article

Notable advances 2014.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1368, doi. 10.1038/nm1214-1368

By:

Keener, Amanda

Publication type:

Article

Drugs that made headlines in 2014.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1370, doi. 10.1038/nm1214-1370

By:

Keener, Amanda

Publication type:

Article

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1458, doi. 10.1038/nm.3709

By:

Clatworthy, Menna R;
Aronin, Caren E Petrie;
Mathews, Rebeccah J;
Morgan, Nicole Y;
Smith, Kenneth G C;
Germain, Ronald N

Publication type:

Article

Europe seeks to streamline drug evaluations in its member states.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1357, doi. 10.1038/nm1214-1357

By:

Sanderson, Katharine

Publication type:

Article

Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1485, doi. 10.1038/nm.3734

By:

Maier, Florian C;
Wehrl, Hans F;
Schmid, Andreas M;
Mannheim, Julia G;
Wiehr, Stefan;
Lerdkrai, Chommanad;
Calaminus, Carsten;
Stahlschmidt, Anke;
Ye, Lan;
Burnet, Michael;
Stiller, Detlef;
Sabri, Osama;
Reischl, Gerald;
Staufenbiel, Mathias;
Garaschuk, Olga;
Jucker, Mathias;
Pichler, Bernd J

Publication type:

Article

A role for interleukin-22 in the alleviation of metabolic syndrome.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1379, doi. 10.1038/nm.3748

By:

Dalmas, Elise;
Donath, Marc Y

Publication type:

Article

Antiangiogenic VEGF-A in peripheral artery disease.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1383, doi. 10.1038/nm.3767

By:

Boucher, Joshua M;
Bautch, Victoria L

Publication type:

Article

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1427, doi. 10.1038/nm.3735

By:

Arruda, Ana Paula;
Pers, Benedicte M;
Parlakgül, Güneş;
Güney, Ekin;
Inouye, Karen;
Hotamisligil, Gökhan S

Publication type:

Article

The Yearbook.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1365, doi. 10.1038/nm1214-1365

By:

Vaidya, Manasi;
Chakradhar, Shraddha

Publication type:

Article

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1394, doi. 10.1038/nm.3716

By:

Hashizume, Rintaro;
Andor, Noemi;
Ihara, Yuichiro;
Lerner, Robin;
Gan, Haiyun;
Chen, Xiaoyue;
Fang, Dong;
Huang, Xi;
Tom, Maxwell W;
Ngo, Vy;
Solomon, David;
Mueller, Sabine;
Paris, Pamela L;
Zhang, Zhiguo;
Petritsch, Claudia;
Gupta, Nalin;
Waldman, Todd A;
James, C David

Publication type:

Article

University travel bans and quarantines may impede Ebola response.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1359, doi. 10.1038/nm1214-1359

By:

Willyard, Cassandra

Publication type:

Article

Principled compassion.

Published in:: Nature Medicine, 2014, v. 20, n. 12, p. 1355, doi. 10.1038/nm.3772
Publication type:: Article

Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1444, doi. 10.1038/nm.3717

By:

Gascon, Eduardo;
Lynch, Kelleen;
Ruan, Hongyu;
Almeida, Sandra;
Verheyden, Jamie M;
Seeley, William W;
Dickson, Dennis W;
Petrucelli, Leonard;
Sun, Danqiong;
Jiao, Jian;
Zhou, Hongru;
Jakovcevski, Mira;
Akbarian, Schahram;
Yao, Wei-Dong;
Gao, Fen-Biao

Publication type:

Article

Old as time: What we can learn from past attempts to treat aging.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1362, doi. 10.1038/nm1214-1362

By:

Hayden, Erika Check

Publication type:

Article

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1472, doi. 10.1038/nm.3733

By:

Xie, Mingchao;
Lu, Charles;
Wang, Jiayin;
McLellan, Michael D;
Johnson, Kimberly J;
Wendl, Michael C;
McMichael, Joshua F;
Schmidt, Heather K;
Yellapantula, Venkata;
Miller, Christopher A;
Ozenberger, Bradley A;
Welch, John S;
Link, Daniel C;
Walter, Matthew J;
Mardis, Elaine R;
Dipersio, John F;
Chen, Feng;
Wilson, Richard K;
Ley, Timothy J;
Ding, Li

Publication type:

Article