Works matching IS 10761551 AND DT 2025 AND VI 31 AND IP 1

Results: 205

Paris saponin VII attenuates psoriasiform inflammation by regulating STAT3/NFκB signaling pathway and Caspase-1-induced pyroptosis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01253-y

By:

Zhou, Xiangnan;
Ning, Jingyuan;
Wu, Doudou;
Liu, Qingwu;
Jiang, Wenbo;
Liu, Jiayi;
Cai, Rui;
Liu, Diangang;
Bai, Yanping

Publication type:

Article

Impaired wound healing in Parkinson's disease: a hypothesis on altered epidermal growth factor (EGF) and N-methyl-D-aspartate (NMDA) signaling in keratinocytes.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01247-w

By:

Liu, Caroline;
Ghebrehiwet-Kuflom, Johanna;
Isseroff, Roslyn Rivkah;
Dahle, Sara;
Morhenn, Vera

Publication type:

Article

Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01206-5

By:

Wang, Shuxuan;
Lin, Yanyan;
Zhao, Qianqian;
Chen, Huanliang;
Du, Shisuo;
Zeng, Zhaochong

Publication type:

Article

Modulating autism spectrum disorder pathophysiology using a trace amine-focused approach: targeting the gut.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01232-3

By:

Pretorius, L.;
Coetzee, J. A.;
Santos, A. P. dos;
Smith, C.

Publication type:

Article

Cytoplasmic HMGB1 promotes the activation of JAK2-STAT3 signaling and PD-L1 expression in breast cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01235-0

By:

Han, Ju-Young;
Rhee, Woo Joong;
Shin, Jeon-Soo

Publication type:

Article

m6A-lncRNA landscape highlights reduced levels of m6A modification in glioblastoma as compared to low-grade glioma.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01254-x

By:

Steponaitis, Giedrius;
Dragunaite, Rugile;
Stakaitis, Rytis;
Sharma, Amit;
Tamasauskas, Arimantas;
Skiriute, Daina

Publication type:

Article

Unveiling metabolic pathways in the hyperglycemic bone: bioenergetic and proteomic analysis of the bone tissue exposed to acute and chronic high glucose.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01251-0

By:

Araújo, Rita;
Bernardino, Raquel L.;
Monteiro, Mariana P.;
Gomes, Pedro S.

Publication type:

Article

Clinically relevant pseudoexons of the GALNS gene and their antisense-based correction.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01243-0

By:

Bychkov, Igor;
Shchukina, Elza;
Zakharova, Ekaterina

Publication type:

Article

Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01245-y

By:

Perez-Moreno, Elisa;
de la Peña, Adely;
Toledo, Tomás;
Saez, Javiera;
Pérez-Molina, Francisca;
Espinoza, Sofía;
Metz, Claudia;
Díaz-Valdivia, Nicole;
Azócar, Lorena;
Prado, Carolina;
Pacheco, Rodrigo;
Segovia-Miranda, Fabian;
Godoy, Alejandro S.;
Amador, Cristian A.;
Feuerhake, Teo;
González, Alfonso;
Soza, Andrea

Publication type:

Article

Inhibition of diacylglycerol O-acyltransferase 1 provides neuroprotection by inhibiting ferroptosis in ischemic stroke.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01255-w

By:

Zeng, Youjie;
Guo, Ren;
Chen, Songhua;
Lin, Yuxin;
Cao, Si;
Wang, Xia;
Zhang, Siyi;
Xu, Huilin;
Qing, Wenxiang;
Yang, Heng;
Ouyang, Wen

Publication type:

Article

Lipocalin-2-mediated ferroptosis as a target for protection against light-induced photoreceptor degeneration.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01250-1

By:

Tang, Wenyi;
Zhai, Ruyi;
Ma, Jun;
Xu, Gezhi

Publication type:

Article

AEOL-induced NRF2 activation and DWORF overexpression mitigate myocardial I/R injury.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01242-1

By:

Asensio-Lopez, Maria del Carmen;
Ruiz-Ballester, Miriam;
Pascual-Oliver, Silvia;
Bastida-Nicolas, Francisco Jose;
Sassi, Yassine;
Fuster, Jose Javier;
Pascual-Figal, Domingo;
Soler, Fernando;
Lax, Antonio

Publication type:

Article

JAK2/STAT3/HMGCS2 signaling aggravates mitochondrial dysfunction and oxidative stress in hyperuricemia-induced cardiac dysfunction.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01246-x

By:

Peng, Dewei;
He, Xiaoli;
Ren, Bowen;
Wang, Qian;
Peng, Lulu;
Jiang, Yue;
Huo, Shengqi;
Men, Lintong;
Shi, Wei;
Luo, Pengcheng;
Zhu, Mengyin;
Zhang, Cuntai;
Lv, Jiagao;
Lin, Li;
Li, Sheng

Publication type:

Article

Comprehensive single-cell transcriptomic reveals different destinies of melanocytes and dynamic changes of immune microenvironment in a psychological stress-induced leukoderma and leukotrichia mouse model.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01236-z

By:

Cao, Xuechen;
Yu, Yongkai;
Yao, Hang;
Zheng, Yujie;
Lu, Jiawei;
Feng, Yifei;
Pei, Tongxin;
Li, Ziyu;
Lu, Ming;
Lu, Yan

Publication type:

Article

Transcriptomic analysis of non-leukemic cell subsets in azacytidine-responsive AML highlights pathways associated with adhesion, platelet aggregation, and angiogenesis in mice and humans.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01233-2

By:

Ebelt, Nancy D.;
Loganathan, Suvithanandhini;
Avsharian, Lara C.;
Manuel, Edwin R.

Publication type:

Article

QRICH1 regulates ATF6 transcription to affect pathological cardiac hypertrophy progression.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01241-2

By:

Zhang, Lihui;
Chen, Hongping;
Zou, Guangmei;
Jia, Wenjuan;
Dong, Haibin;
Wang, Chunxiao;
Wang, Hua;
Liu, Yugang;
Teng, Da;
Xu, Bowen;
Zhong, Lin;
Gong, Lei;
Yang, Jun

Publication type:

Article

Correction: NEK8 promotes the progression of gastric cancer by reprogramming asparagine metabolism.

Published in:

2025

By:

Wang, Mingliang;
Yu, Kexun;
Meng, Futao;
Wang, Huizhen;
Li, Yongxiang

Publication type:

Correction Notice

Melatonin alleviates sepsis-induced acute lung injury by inhibiting necroptosis via reducing circulating mtDNA release.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01228-z

By:

Peng, Yuce;
Xu, Jia;
Wei, Lingyu;
Luo, Minghao;
Chen, Shenglong;
Wei, Xuebiao;
Luo, Suxin;
Su, Zedazhong;
Wang, Zhonghua

Publication type:

Article

Unraveling the complex genetic landscape of OTOF-related hearing loss: a deep dive into cryptic variants and haplotype phasing.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01225-2

By:

Lin, Pei-Hsuan;
Tsai, Cheng-Yu;
Chiang, Yu-Ting;
Ho, Chang-Han;
Lu, Yue-Sheng;
Hsu, Jacob Shu-Jui;
Cheng, Yen-Fu;
Tsai, Shih-Feng;
Hsu, Chuan-Jen;
Chen, Pei-Lung;
Wu, Chen-Chi

Publication type:

Article

The MYC/TXNIP axis mediates NCL-Suppressed CD8<sup>+</sup>T cell immune response in lung adenocarcinoma.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01224-3

By:

Xiao, Dan;
Chen, Tanxiu;
Yu, Xinlin;
Song, Ying;
Liu, Yigang;
Yan, Wei

Publication type:

Article

Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for immunotherapy in breast cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01237-y

By:

Wang, Hongwei;
Zhu, Yu-nan;
Zhang, Sifan;
Liu, Kexin;
Huang, Rong;
Li, Zhigao;
Mei, Lan;
Li, Yingpu

Publication type:

Article

Melatonin alleviates sepsis-induced acute lung injury by inhibiting necroptosis via reducing circulating mtDNA release.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01228-z

By:

Peng, Yuce;
Xu, Jia;
Wei, Lingyu;
Luo, Minghao;
Chen, Shenglong;
Wei, Xuebiao;
Luo, Suxin;
Su, Zedazhong;
Wang, Zhonghua

Publication type:

Article

Enhanced potency of immune checkpoint inhibitors against poorly immunological solid tumors by immune stimulatory oncolytic adenoviruses-mediated remodeling of the tumor microenvironment.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01223-4

By:

Ahn, Hyo Min;
Jung, Bo-Kyeong;
Hong, JinWoo;
Hong, Dayoung;
Yoon, A-Rum;
Yun, Chae-Ok

Publication type:

Article

Surgery/anesthesia may cause monocytes to promote tumor development.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01213-6

By:

Wang, Yang-Yang;
Zhu, Rui-Lou;
Chang, En-Qiang;
Liu, Xiao-Zhuan;
Wang, Guang-Zhi;
Li, Ning-Tao;
Zhang, Wei;
Zhou, Jun;
Sun, Ming-Yang;
Zou, Xin;
Hao, Jie;
Zhang, Jia-Qiang

Publication type:

Article

COX-2 inhibition as a therapeutic strategy for bone loss in Staphylococcus aureus osteomyelitis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01202-9

By:

Chen, Yuhui;
Li, Chao;
Jia, Jishan;
Jiang, Yuhui;
Zhang, Ping;
Cheng, Caiyu;
Zhang, Guangyan;
Gao, Lang;
Yang, Xiang;
Zhao, Jiawei;
Li, Kaiqun;
Yu, Bin

Publication type:

Article

Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01240-3

By:

Chen, Zhifeng;
Wo, Da;
Wu, Celiang;
Ma, En;
Peng, Jinhui;
Zhu, Weidong;
Ren, Dan-ni

Publication type:

Article

A pilot study on the effect of SARS-CoV-2 spike protein on IL-1β-mediated inflammation in peripheral blood immune cells from AIED patients.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01227-0

By:

Pathak, Shresh;
Tan, Natalie;
Vambutas, Andrea

Publication type:

Article

Exosomes derived from human amniotic mesenchymal stem cells promotes angiogenesis in hUVECs by delivering novel miRNA N-194.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01192-8

By:

Song, Yang;
Zhang, Tao;
Shi, Ping;
Gao, Yingzhuo;
Pang, Xining

Publication type:

Article

NEK8 promotes the progression of gastric cancer by reprogramming asparagine metabolism.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-024-01062-9

By:

Wang, Mingliang;
Yu, Kexun;
Meng, Futao;
Wang, Huizhen;
Li, Yongxiang

Publication type:

Article

Drug screening targeting TREM2-TYROBP transmembrane binding.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01229-y

By:

Cobas-Carreño, M.;
Esteban-Martos, A.;
Tomas-Gallardo, L.;
Iribarren, I.;
Gonzalez-Palma, L.;
Rivera-Ramos, A.;
Elena-Guerra, J.;
Alarcon-Martin, E.;
Ruiz, R.;
Bravo, M. J.;
Venero, J. L.;
Morató, X.;
Ruiz, A.;
Royo, J. L.

Publication type:

Article

Bacteriophage-derived endolysins restore antibiotic susceptibility in β-lactam- and macrolide-resistant Streptococcus pneumoniae infections.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01226-1

By:

Vander Elst, Niels;
Farmen, Kristine;
Knörr, Lisa;
Merlijn, Lotte;
Iovino, Federico

Publication type:

Article

Inhibition of TLR4 mitigates sensorineural hearing loss resulting from cochlear inflammation.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01219-0

By:

Lou, Jintao;
Wu, Fan;
Liu, Wei;
Hu, Rui;
He, Wuhui;
Feng, Yisi;
Huang, Yan;
Guo, Jia;
Deng, Jingman;
Zhao, Zhen;
Zhang, Zhigang;
Si, Yu

Publication type:

Article

Recent advances in the roles of extracellular vesicles in cardiovascular diseases: pathophysiological mechanisms, biomarkers, and cell-free therapeutic strategy.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01200-x

By:

Wang, Mengyang;
Chen, Yuwu;
Xu, Biyi;
Zhu, Xinxin;
Mou, Junke;
Xie, Jiani;
Che, Ziao;
Zuo, Liyang;
Li, Ji;
Jia, Haibo;
Yu, Bo

Publication type:

Article

Calpain1 inhibition enhances autophagy-lysosomal pathway and ameliorates tubulointerstitial fibrosis in Nephronophthisis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01231-4

By:

Li, Dantong;
Zhang, Jinglan;
Su, Xinyu;
Yang, Yichen;
Lai, Jiayong;
Wei, Xiaoya;
Chen, Huamu;
Liu, Yaqing;
Wang, Haiyan;
Sun, Liangzhong

Publication type:

Article

STMN1–IGFBP5 axis induces senescence and extracellular matrix degradation in nucleus pulposus cells: In vivo and in vitro insights.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01220-7

By:

Li, Lei;
Zhang, Guangzhi;
Yang, Zhili;
Cao, Zhenyu;
Wang, Dongxin;
Kang, Xuewen

Publication type:

Article

Peripheral tissue BDNF expression is affected by promoter IV defect and enriched environments in mice: negative hippocampus-intestine and positive thymus-serum-muscle correlations.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01196-4

By:

Wang, Janet;
Schupp, William;
Sakata, Kazuko

Publication type:

Article

USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01182-w

By:

Wang, Zhiyong;
Yu, Cheng;
Xie, Gengchen;
Tao, Kaixiong;
Yin, Zhijie;
Lv, Qing

Publication type:

Article

Electron-beam FLASH whole brain irradiation induced a unique changes of intestinal flora.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-024-01053-w

By:

Gao, Feifei;
Cheng, Wei;
Ma, Yanxi;
Yu, Boyi;
Lang, Xinle;
Jin, Xiaodong;
Wang, Jianxin;
Liu, Xianhong;
Di, Cuixia;
Wang, Hui;
Ye, Fei;
Zhao, Ting;
Chen, Weiqiang;
Li, Qiang

Publication type:

Article

CNPY3's regulation of tumor microenvironment and its impact on colon cancer aggressiveness.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01145-1

By:

Gao, Xucan;
Zhou, Biaohuan;
Feng, Xiudong;
Ji, Zhouxin;
Li, Qiang;
Liu, Huining

Publication type:

Article

Empagliflozin ameliorates renal and metabolic derangements in obese type 2 diabetic mice by blocking advanced glycation end product–receptor axis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01138-0

By:

Matsui, Takanori;
Sotokawauchi, Ami;
Nishino, Yuri;
Koga, Yoshinori;
Yamagishi, Sho-ichi

Publication type:

Article

Empagliflozin ameliorates renal and metabolic derangements in obese type 2 diabetic mice by blocking advanced glycation end product–receptor axis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01138-0

By:

Matsui, Takanori;
Sotokawauchi, Ami;
Nishino, Yuri;
Koga, Yoshinori;
Yamagishi, Sho-ichi

Publication type:

Article

A genome-wide association study identifies a novel East Asian–specific locus for dementia with Lewy bodies in Japanese subjects.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01115-7

By:

Mitsumori, Risa;
Asanomi, Yuya;
Morizono, Takashi;
Shigemizu, Daichi;
Niida, Shumpei;
Ozaki, Kouichi

Publication type:

Article

Cholesterol promotes hair growth through activating sympathetic nerves and enhancing the proliferation of hair follicle stem cells.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01139-z

By:

Guo, Mengchen;
Jiang, Junkun;
Zhang, Anke;
Yu, Wenjing;
Huang, Xin

Publication type:

Article

miR-6516-3p-mediated downregulation of the endogenous MMP-9 inhibitor RECK in mesangial cells might exacerbate lupus nephritis.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01124-6

By:

Tomita, Hiroyuki;
Hayakawa, Kunihiro;
Ikeda, Keigo;
Tsushima, Hiroshi;
Shinoura, Marina;
Fujishiro, Maki;
Kataoka, Yuko;
Yamaji, Ken;
Takamori, Kenji;
Tamura, Naoto;
Sekigawa, Iwao;
Morimoto, Shinji

Publication type:

Article

Natural flavonoid Orientin restricts 5-Fluorouracil induced cancer stem cells mediated angiogenesis by regulating HIF1α and VEGFA in colorectal cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-024-01032-1

By:

Ghosh, Rituparna;
Bhowmik, Arijit;
Biswas, Souradeep;
Samanta, Priya;
Sarkar, Rupali;
Pakhira, Shampa;
Mondal, Mrinmoyee;
Hajra, Subhadip;
Saha, Prosenjit

Publication type:

Article

Effects of hydrogel stiffness and viscoelasticity on organoid culture: a comprehensive review.

Published in:

2025

By:

Lai, Wei;
Geliang, Hu;
Bin, Xu;
Wang, Wei

Publication type:

Literature Review

Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01134-4

By:

Hao, Yi;
Li, Zhongzhong;
Du, Xinyan;
Xie, Qingsong;
Li, Dongxiao;
Lei, Shaoyuan;
Guo, Yansu

Publication type:

Article

Constitutive systemic inflammation in Shwachman-Diamond Syndrome.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01133-5

By:

Sabbioni, Giuseppe;
D'Aversa, Elisabetta;
Breveglieri, Giulia;
Altieri, Maria Teresa;
Boni, Christian;
Pegoraro, Anna;
Finotti, Alessia;
Gambari, Roberto;
D'Amico, Giovanna;
Vella, Antonio;
Lippi, Giuseppe;
Cipolli, Marco;
Bezzerri, Valentino;
Borgatti, Monica

Publication type:

Article

Instantaneous dose rate as a crucial factor in reducing mortality and normal tissue toxicities in murine total-body irradiation: a comparative study of dose rate combinations.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01135-3

By:

Zhu, Hongyu;
Liu, Shihua;
Qiu, Jiaqi;
Hu, Ankang;
Zhou, Wanyi;
Wang, Jian;
Gu, Weihang;
Zhu, Yinuo;
Zha, Hao;
Xiang, Rong;
Li, Junli;
Qiu, Rui;
Zhao, Chong;
Huang, Peng;
Deng, Xiaowu

Publication type:

Article

Caveolin-3: therapeutic target for diabetic myocardial ischemia/reperfusion injury.

Published in:

2025

By:

Wen, Xinyu;
Ji, Yanwei;
Tang, Hepeng;
Jin, Zhenshuai;
Su, Wating;
Zhou, Lu;
Xia, Zhong-Yuan;
Li, Lin;
Lei, Shaoqing

Publication type:

Literature Review