Works in Molecular Medicine, 2025, Vol 31, Issue 1
Results: 92
Piezo1 promotes intervertebral disc degeneration through the Ca<sup>2+</sup>/F-actin/Yap signaling axis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01147-z
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- Article
CNPY3's regulation of tumor microenvironment and its impact on colon cancer aggressiveness.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01145-1
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- Article
Empagliflozin ameliorates renal and metabolic derangements in obese type 2 diabetic mice by blocking advanced glycation end product–receptor axis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01138-0
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- Article
Empagliflozin ameliorates renal and metabolic derangements in obese type 2 diabetic mice by blocking advanced glycation end product–receptor axis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01138-0
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- Article
A genome-wide association study identifies a novel East Asian–specific locus for dementia with Lewy bodies in Japanese subjects.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01115-7
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- Article
Cholesterol promotes hair growth through activating sympathetic nerves and enhancing the proliferation of hair follicle stem cells.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01139-z
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- Article
miR-6516-3p-mediated downregulation of the endogenous MMP-9 inhibitor RECK in mesangial cells might exacerbate lupus nephritis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01124-6
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- Article
Natural flavonoid Orientin restricts 5-Fluorouracil induced cancer stem cells mediated angiogenesis by regulating HIF1α and VEGFA in colorectal cancer.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-024-01032-1
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- Article
Effects of hydrogel stiffness and viscoelasticity on organoid culture: a comprehensive review.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01131-7
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- Article
Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01134-4
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- Article
Constitutive systemic inflammation in Shwachman-Diamond Syndrome.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01133-5
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- Article
Instantaneous dose rate as a crucial factor in reducing mortality and normal tissue toxicities in murine total-body irradiation: a comparative study of dose rate combinations.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01135-3
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- Article
Caveolin-3: therapeutic target for diabetic myocardial ischemia/reperfusion injury.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01117-5
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- Article
A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01130-8
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- Article
CPEB3 can regulate seizure susceptibility by inhibiting the transcriptional activity of STAT3 on NMDARs expression.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01136-2
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- Article
Integrated metabolomics and transcriptomics reveal the potential of hydroxy-alpha-sanshool in alleviating insulin resistance.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01129-1
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- Article
CYFIP1 coordinate with RNMT to induce osteosarcoma cuproptosis via AURKAIP1 m7G modification.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01127-3
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- Article
FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01126-4
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- Article
Mesenchymal stem cells and mesenchymal stem cell-derived exosomes: a promising strategy for treating retinal degenerative diseases.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01120-w
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- Article
The vasoconstrictor adenosine 5′-tetraphosphate is a danger signal that induces IL-1β.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01116-6
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- Article
Matrix metalloproteinases and their tissue inhibitors as upcoming biomarker signatures of connective tissue diseases-related interstitial lung disease: towards an earlier and accurate diagnosis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01128-2
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- Article
DLAT activates EMT to promote HCC metastasis by regulating GLUT1-mediated aerobic glycolysis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01125-5
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- Article
Cancer-secreted exosomal miR-1246 promotes colorectal cancer liver metastasis by activating hepatic stellate cells.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01112-w
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- Article
Radiation symptoms resemble laminopathies and the physical underlying cause may sit at the lamin A C-terminus.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01081-0
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- Article
High-salt diet decreases FOLFOX efficacy via gut bacterial tryptophan metabolism in colorectal cancer.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01122-8
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- Article
Molecular mechanisms of m6A modifications regulating tumor radioresistance.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01121-9
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- Article
RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01119-3
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- Article
Gαq/11 aggravates acute lung injury in mice by promoting endoplasmic reticulum stress-mediated NETosis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01118-4
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- Article
Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01098-5
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Pharmacogenomics-based subtype decoded implications for risk stratification and immunotherapy in pancreatic adenocarcinoma.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-024-01049-6
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- Article
Type 3 diabetes and metabolic reprogramming of brain neurons: causes and therapeutic strategies.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01101-z
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- Article
Integrating advanced analytical methods to assess epigenetic marks affecting response to hypomethylating agents in higher risk myelodysplastic syndrome.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01123-7
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- Article
Targeting NINJ1-mediated cell rupture to treat inflammatory diseases.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01113-9
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The interplay between gut bacteria and targeted therapies: implications for future cancer treatments.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01108-6
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Human cytomegalovirus tegument protein UL23 promotes gastric cancer immune evasion by facilitating PD-L1 transcription.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01114-8
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Licochalcone A prevents cognitive decline in a lipopolysaccharide-induced neuroinflammation mice model.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01106-8
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- Article
Miglustat ameliorates isoproterenol-induced cardiac fibrosis via targeting UGCG.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01093-w
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- Article
Odoribacter splanchnicus-derived extracellular vesicles alleviate inflammatory bowel disease by modulating gastrointestinal inflammation and intestinal barrier function via the NLRP3 inflammasome suppression.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01063-2
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- Article
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01086-9
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01075-y
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- Article
Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01094-9
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- Article
TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01103-x
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Harnessing amino acid pathways to influence myeloid cell function in tumor immunity.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01099-4
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Role of exercise on ncRNAs and exosomal ncRNAs in preventing neurodegenerative diseases: a narrative review.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01091-y
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- Article
Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01110-y
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- Article
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m<sup>6</sup>A-dependent manner.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01095-8
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- Article
Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01104-w
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Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01107-7
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Role of HNF6 in liver homeostasis and pathophysiology.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01105-9
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- Article
Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01090-z
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- Article