Works in Molecular Medicine, 2020, Vol 26, Issue 1

Results: 126

Retraction Note: The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00265-0

By:

Sitapara, Ravikumar A.;
Antoine, Daniel J.;
Sharma, Lokesh;
Patel, Vivek S.;
Ashby, Charles R.;
Gorasiya, Samir;
Yang, Huan;
Zur, Michelle;
Mantell, Lin L.

Publication type:

Article

Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00264-1

By:

Yang, Huan;
Lundbäck, Peter;
Ottosson, Lars;
Erlandsson-Harris, Helena;
Venereau, Emilie;
Bianchi, Marco E.;
Al-Abed, Yousef;
Andersson, Ulf;
Tracey, Kevin J.;
Antoine, Daniel J.

Publication type:

Article

Retraction Note to: High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00263-2

By:

Palmblad, Karin;
Schierbeck, Hanna;
Sundberg, Erik;
Horne, Anna-Carin;
Harris, Helena Erlandsson;
Henter, Jan-Inge;
Antoine, Daniel J.;
Andersson, Ulf

Publication type:

Article

Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00262-3

By:

Antoine, Daniel James;
Williams, Dominic P.;
Kipar, Anja;
Laverty, Hugh;
Park, B. Kevin

Publication type:

Article

Correction to: miRNA-23b as a biomarker of culture-positive neonatal sepsis.

Published in:

2020

By:

Fatmi, Ahlam;
Rebiahi, Sid Ahmed;
Chabni, Nafissa;
Zerrouki, Hanane;
Azzaoui, Hafsa;
Elhabiri, Yamina;
Benmansour, Souheila;
Ibáñez-Cabellos, José Santiago;
Smahi, Mohammed Chems-Eddine;
Aribi, Mourad;
García-Giménez, José Luis;
Pallardó, Federico V.

Publication type:

Correction Notice

Autosomal dominant polycystic kidney disease and pioglitazone for its therapy: a comprehensive review with an emphasis on the molecular pathogenesis and pharmacological aspects.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00246-3

By:

Saini, Aryendu Kumar;
Saini, Rakesh;
Singh, Shubham

Publication type:

Article

Escape from X chromosome inactivation and female bias of autoimmune diseases.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00256-1

By:

Mousavi, Mohammad Javad;
Mahmoudi, Mahdi;
Ghotloo, Somayeh

Publication type:

Article

The involvement of neuroimmune cells in adipose innervation.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00254-3

By:

Blaszkiewicz, Magdalena;
Wood, Elizabeth;
Koizar, Sigi;
Willows, Jake;
Anderson, Ryan;
Tseng, Yu-Hua;
Godwin, James;
Townsend, Kristy L.

Publication type:

Article

Identification of an RNA binding protein-related gene signature in hepatocellular carcinoma patients.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00252-5

By:

Wang, Li;
Zhou, Na;
Qu, Jialin;
Jiang, Man;
Zhang, Xiaochun

Publication type:

Article

High-expression of ROCK1 modulates the apoptosis of lens epithelial cells in age-related cataracts by targeting p53 gene.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00251-6

By:

Hu, Shanshan;
Su, Dongmei;
Sun, Lei;
Wang, Zhongying;
Guan, Lina;
Liu, Shanhe;
Zhao, Baowen;
Liu, Yong;
Shi, Cuige;
Yu, Jianbo;
Ma, Xu

Publication type:

Article

Variant in NHLRC2 leads to increased hnRNP C2 in developing neurons and the hippocampus of a mouse model of FINCA disease.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00245-4

By:

Hiltunen, Anniina E.;
Kangas, Salla M.;
Ohlmeier, Steffen;
Pietilä, Ilkka;
Hiltunen, Jori;
Tanila, Heikki;
McKerlie, Colin;
Govindan, Subashika;
Tuominen, Hannu;
Kaarteenaho, Riitta;
Hallman, Mikko;
Uusimaa, Johanna;
Hinttala, Reetta

Publication type:

Article

microRNA-199a-5p regulates epithelial-to-mesenchymal transition in diabetic cataract by targeting SP1 gene.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00250-7

By:

Liu, Xin;
Gong, Qiaoyun;
Yang, Longfei;
Liu, Min;
Niu, Lingzhi;
Wang, Lufei

Publication type:

Article

Targeting the eCIRP/TREM-1 interaction with a small molecule inhibitor improves cardiac dysfunction in neonatal sepsis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00243-6

By:

Denning, Naomi-Liza;
Aziz, Monowar;
Diao, Li;
Prince, Jose M.;
Wang, Ping

Publication type:

Article

Early detection of steroid-induced femoral head necrosis using <sup>99m</sup>Tc-Cys-Annexin V-based apoptosis imaging in a rabbit model.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00248-1

By:

Wang, Xiaolong;
Li, Jianbo;
Man, Da;
Liu, Rui;
Zhao, Jianmin

Publication type:

Article

Vagal afferent fibers contribute to the anti-inflammatory reactions by vagus nerve stimulation in concanavalin A model of hepatitis in rats.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00247-2

By:

Jo, Byung Gon;
Kim, Seung-Hyung;
Namgung, Uk

Publication type:

Article

RCAN1 in cardiovascular diseases: molecular mechanisms and a potential therapeutic target.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00249-0

By:

Wang, Shuai;
Wang, Yuqing;
Qiu, Kaixin;
Zhu, Jin;
Wu, Yili

Publication type:

Article

Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00244-5

By:

Hartin, Samantha N.;
Means, John C.;
Alaimo, Joseph T.;
Younger, Scott T.

Publication type:

Article

MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00242-7

By:

Qu, Chuan;
Liu, Xin;
Guo, Yan;
Fo, Yuhong;
Chen, Xiuhuan;
Zhou, Jining;
Yang, Bo

Publication type:

Article

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00227-6

By:

Lin, Minjie;
Long, Jungke;
Li, Wenbo;
Yang, Chenxuan;
Loughran, Patricia;
O'Doherty, Robert;
Billiar, Timothy R.;
Deng, Meihong;
Scott, Melanie J.

Publication type:

Article

Silencing long non-coding RNA XIST suppresses drug resistance in acute myeloid leukemia through down-regulation of MYC by elevating microRNA-29a expression.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00229-4

By:

Wang, Chong;
Li, Lingling;
Li, Mengya;
Wang, Weiqiong;
Liu, Yanfang;
Wang, Shujuan

Publication type:

Article

LncRNA KCNA2-AS regulates spinal astrocyte activation through STAT3 to affect postherpetic neuralgia.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00232-9

By:

Kong, Cunlong;
Du, Jie;
Bu, Huilian;
Huang, Chen;
Xu, Fuxing;
Ren, Huan

Publication type:

Article

LncRNA LUADT1 sponges miR-195 to prevent cardiac endothelial cell apoptosis in sepsis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00228-5

By:

Zhang, Zhimin;
Lv, Mingzhu;
Wang, Xiang;
Zhao, Zheng;
Jiang, Daolong;
Wang, Lihua

Publication type:

Article

PTEN inhibitor improves vascular remodeling and cardiac function after myocardial infarction through PI3k/Akt/VEGF signaling pathway.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00241-8

By:

Feng, Qiuting;
Li, Xing;
Qin, Xian;
Yu, Cheng;
Jin, Yan;
Qian, Xiaojun

Publication type:

Article

Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00238-3

By:

Bam, Marpe;
Yang, Xiaoming;
Busbee, Brandon P.;
Aiello, Allison E.;
Uddin, Monica;
Ginsberg, Jay P.;
Galea, Sandro;
Nagarkatti, Prakash S.;
Nagarkatti, Mitzi

Publication type:

Article

ZLM-7 inhibits the occurrence and angiogenesis of breast cancer through miR-212-3p/Sp1/VEGFA signal axis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00239-2

By:

Li, Xuan;
Zou, Zi-Zheng;
Wen, Min;
Xie, Yuan-Zhu;
Peng, Kun-Jian;
Luo, Tiao;
Liu, Su-You;
Gu, Qin;
Li, Ji-Jia;
Luo, Zhi-Yong

Publication type:

Article

Fibroblast growth factor-2 alleviates the capillary leakage and inflammation in sepsis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00221-y

By:

Pan, Xiaojun;
Xu, Shunyao;
Zhou, Zhen;
Wang, Fen;
Mao, Lingjie;
Li, Hao;
Wu, Caixia;
Wang, Junfeng;
Huang, Yueyue;
Li, Dequan;
Wang, Cong;
Pan, Jingye

Publication type:

Article

Electroacupuncture reduces scopolamine-induced amnesia via mediating the miR-210/SIN3A and miR-183/SIN3A signaling pathway.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00233-8

By:

Ye, Fan;
Tian, Shiming;
Hu, Huimin;
Yu, Zhengwen

Publication type:

Article

Long noncoding RNA HCG18 inhibits the differentiation of human bone marrow-derived mesenchymal stem cells in osteoporosis by targeting miR-30a-5p/NOTCH1 axis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00219-6

By:

Che, Mingxue;
Gong, Weiquan;
Zhao, Yao;
Liu, Mingxi

Publication type:

Article

Acupuncture protects against cerebral ischemia–reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00236-5

By:

Sun, Xiaowei;
Liu, Hao;
Sun, Zhongren;
Zhang, Beng;
Wang, Xinyu;
Liu, Tingting;
Pan, Tingting;
Gao, Ying;
Jiang, Xicheng;
Li, Hongtao

Publication type:

Article

Downregulation of long noncoding RNA DLEU1 attenuates hypersensitivity in chronic constriction injury-induced neuropathic pain in rats by targeting miR-133a-3p/SRPK1 axis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00235-6

By:

Li, Zhen;
Li, Aiyuan;
Yan, Liping;
Yang, Tian;
Xu, Wei;
Fan, Pengju

Publication type:

Article

SARS-CoV-2 and interferon blockade.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00231-w

By:

Diamond, Betty;
Volpe, Bruce T.;
VanPatten, Sonya;
Al Abed, Yousef

Publication type:

Article

Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00225-8

By:

Pecze, Laszlo;
Randi, Elisa B.;
Szabo, Csaba

Publication type:

Article

The roles of the gut microbiota–miRNA interaction in the host pathophysiology.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00234-7

By:

Li, Meihong;
Chen, Wei-Dong;
Wang, Yan-Dong

Publication type:

Article

Different stability of miRNAs and endogenous control genes in archival specimens of papillary thyroid carcinoma.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00218-7

By:

Pamedytyte, Daina;
Leipute, Enrika;
Zilaitiene, Birute;
Sarauskas, Valdas;
Dauksiene, Dalia;
Dauksa, Albertas;
Zvirbliene, Aurelija

Publication type:

Article

Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in bronchopulmonary dysplasia development.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00237-4

By:

Wang, Di;
Hong, Hui;
Li, Xiao-Xia;
Li, Jing;
Zhang, Zhi-Qun

Publication type:

Article

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00224-9

By:

Sitapara, Ravikumar A.;
Gauthier, Alex G.;
Patel, Vivek S.;
Lin, Mosi;
Zur, Michelle;
Ashby, Charles R.;
Mantell, Lin L.

Publication type:

Article

IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00230-x

By:

Chen, Yu;
Wang, Jinglan;
Liu, Chenxi;
Su, Longxiang;
Zhang, Dong;
Fan, Junping;
Yang, Yanli;
Xiao, Meng;
Xie, Jing;
Xu, Yingchun;
Li, Yongzhe;
Zhang, Shuyang

Publication type:

Article

Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00226-7

By:

Du, Lei;
Li, Cong-Rong;
He, Qi-Feng;
Li, Xiao-Hua;
Yang, Lin-Fei;
Zou, Yuan;
Yang, Zhi-Xia;
Zhang, Dong;
Xing, Xiao-Wei

Publication type:

Article

Alveolar cells under mechanical stressed niche: critical contributors to pulmonary fibrosis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00223-w

By:

Yang, Juntang;
Pan, Xin;
Wang, Lan;
Yu, Guoying

Publication type:

Article

miRNA-23b as a biomarker of culture-positive neonatal sepsis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00217-8

By:

Fatmi, Ahlam;
Rebiahi, Sid Ahmed;
Chabni, Nafissa;
Zerrouki, Hanane;
Azzaoui, Hafsa;
Elhabiri, Yamina;
Benmassour, Souheila;
Ibáñez-Cabellos, José Santiago;
Smahi, Mohammed Chems-Eddine;
Aribi, Mourad;
García-Giménez, José Luis;
Pallardó, Federico V.

Publication type:

Article

DNA methylation microarrays identify epigenetically regulated lipid related genes in obese patients with hypercholesterolemia.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00220-z

By:

Płatek, Teresa;
Polus, Anna;
Góralska, Joanna;
Raźny, Urszula;
Gruca, Anna;
Kieć-Wilk, Beata;
Zabielski, Piotr;
Kapusta, Maria;
Słowińska-Solnica, Krystyna;
Solnica, Bogdan;
Malczewska-Malec, Małgorzata;
Dembińska-Kieć, Aldona

Publication type:

Article

Serum a proliferation-inducing ligand and MicroRNA-223 are associated with rheumatoid arthritis: diagnostic and prognostic implications.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00199-7

By:

Taha, Mohamed;
Shaker, Olfat Gamil;
Abdelsalam, Enas;
Taha, Noha

Publication type:

Article

The role of host defences in Covid 19 and treatments thereof.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00216-9

By:

Dattilo, Maurizio

Publication type:

Article

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00215-w

By:

Weber, Andrew G.;
Chau, Alice S.;
Egeblad, Mikala;
Barnes, Betsy J.;
Janowitz, Tobias

Publication type:

Article

SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00210-1

By:

Jiang, Jihong;
Hu, Baoji;
Chung, Chun-Shiang;
Chen, Yaping;
Zhang, Yunhe;
Tindal, Elizabeth W.;
Li, Jinbao;
Ayala, Alfred

Publication type:

Article

Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00197-9

By:

Huang, Long;
Jiang, Xiao-Liu;
Liang, Hong-Bin;
Li, Jian-Cheng;
Chin, Li-Han;
Wei, Jian-Ping;
Wang, Rui-Ru;
Cai, Jing;
Xiong, Qiang;
Wang, Lien-Tu;
Cram, David S.;
Liu, An-Wen

Publication type:

Article

Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00212-z

By:

Wortmann, Markus;
Arshad, Muhammad;
Hakimi, Maani;
Böckler, Dittmar;
Dihlmann, Susanne

Publication type:

Article

Comparison of time and dose dependent gene expression and affected pathways in primary human fibroblasts after exposure to ionizing radiation.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00203-0

By:

Brackmann, Lara Kim;
Poplawski, Alicia;
Grandt, Caine Lucas;
Schwarz, Heike;
Hankeln, Thomas;
Rapp, Steffen;
Zahnreich, Sebastian;
Galetzka, Danuta;
Schmitt, Iris;
Grad, Christian;
Eckhard, Lukas;
Mirsch, Johanna;
Blettner, Maria;
Scholz-Kreisel, Peter;
Hess, Moritz;
Binder, Harald;
Schmidberger, Heinz;
Marron, Manuela

Publication type:

Article

THRIL mediates endothelial progenitor cells autophagy via AKT pathway and FUS.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00201-2

By:

Xiao, Jiandong;
Lu, Yuli;
Yang, Xinchun

Publication type:

Article

The crosstalk of ABCA1 and ANXA1: a potential mechanism for protection against atherosclerosis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00213-y

By:

Shen, Xin;
Zhang, Shun;
Guo, Zhu;
Xing, Dongming;
Chen, Wujun

Publication type:

Article