Works matching IS 10614036 AND DT 2015 AND VI 47 AND IP 11

Results: 22

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1282, doi. 10.1038/ng.3405
By:
- Loh, Marie;
- Zhang, Weihua;
- Saleheen, Danish;
- Wahl, Simone;
- Tan, Sian-Tsung;
- Scott, William R;
- Afzal, Uzma;
- Ahluwalia, Tarunveer S;
- Esko, Tõnu;
- Harris, Sarah E;
- Hartiala, Jaana;
- Khor, Chiea-Chuen;
- Stewart, Alexandre F R;
- Wu, Jer-Yuarn;
- Zhang, Yi;
- Lyytikäinen, Leo-Pekka;
- Postmus, Iris;
- Raitakari, Olli T;
- Traglia, Michela;
- Barroso, Inês
Publication type:
Article
Standardized phenotyping enhances Mendelian disease gene identification.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1222, doi. 10.1038/ng.3425
By:
- Veltman, Joris A;
- Vissers, Lisenka E L M
Publication type:
Article
A new genomic island.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1221, doi. 10.1038/ng.3436
Publication type:
Article
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1260, doi. 10.1038/ng.3376
By:
- Guimier, Anne;
- Liu, Hui;
- Noll, Aaron;
- El Malti, Rajae;
- Smith, Laurie D;
- Jimenez, Gina;
- Miller, Neil A;
- Oufadem, Myriam;
- Moreau de Bellaing, Anne;
- Saunders, Carol J;
- Thiffault, Isabelle;
- Bole-Feysot, Christine;
- Cooley, Linda D;
- Farrow, Emily G;
- Masson, Cécile;
- Nitschké, Patrick;
- Lyonnet, Stanislas;
- de Pontual, Loic;
- Bonnet, Damien;
- Kingsmore, Stephen F
Publication type:
Article
Height-reducing variants and selection for short stature in Sardinia.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1352, doi. 10.1038/ng.3403
By:
- Sidore, Carlo;
- Mulas, Antonella;
- Maschio, Andrea;
- Floris, Matteo;
- Soranzo, Nicole;
- Uzzau, Sergio;
- Angius, Andrea;
- Cucca, Francesco;
- Zoledziewska, Magdalena;
- Sanna, Serena;
- Steri, Maristella;
- Busonero, Fabio;
- Marongiu, Michele;
- Concas, Maria Pina;
- Murgia, Federico;
- Vaccargiu, Simona;
- Tachmazidou, Ioanna;
- Zeggini, Eleftheria;
- Dedoussis, George;
- Jones, Chris
Publication type:
Article
Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1249, doi. 10.1038/ng.3402
By:
- González, Alvaro J;
- Setty, Manu;
- Leslie, Christina S
Publication type:
Article
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1346, doi. 10.1038/ng.3419
By:
- Li, Fugen;
- Takeda, David Y;
- Cejas, Paloma;
- Shivdasani, Ramesh A;
- Hahn, William C;
- Brown, Myles;
- Loda, Massimo;
- Long, Henry W;
- Freedman, Matthew L;
- Pomerantz, Mark M;
- Lenci, Romina;
- Chonkar, Apurva;
- Chabot, Matthew;
- Cook, Jennifer;
- Kantoff, Philip W;
- Vazquez, Francisca;
- Bowden, Michaela;
- Lis, Rosina
Publication type:
Article
Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1363, doi. 10.1038/ng.3410
By:
- Foulds, Nicola;
- Akawi, Nadia;
- McRae, Jeremy;
- Clayton, Stephen;
- Fitzgerald, Tomas W;
- Gerety, Sebastian S;
- Jones, Wendy D;
- King, Daniel;
- Lelliott, Chris;
- Lord, Jenny;
- Piombo, Virginia;
- Prigmore, Elena;
- Rajan, Diana;
- Sifrim, Alejandro;
- Swaminathan, Ganesh J;
- Wright, Caroline F;
- Barrett, Jeffrey C;
- Hurles, Matthew E;
- Joss, Shelagh;
- O'Regan, Mary
Publication type:
Article
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1316, doi. 10.1038/ng.3413
By:
- Kretzmer, Helene;
- Bernhart, Stephan H;
- Bergmann, Anke K;
- Doose, Gero;
- Jühling, Frank;
- Otto, Christian;
- Eberth, Sonja;
- Eils, Roland;
- Stadler, Peter F;
- Hoffmann, Steve;
- Wang, Wei;
- Hovestadt, Volker;
- Picelli, Simone;
- Lichter, Peter;
- Radlwimmer, Bernhard;
- Drexler, Hans G;
- MacLeod, Roderick A F;
- Flicek, Paul;
- Haas, Siegfried;
- Hummel, Michael
Publication type:
Article
The genomic landscape of adult T cell leukemia/lymphoma.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1226, doi. 10.1038/ng.3428
By:
- Vicente, Carmen;
- Cools, Jan
Publication type:
Article
Population genetic differentiation of height and body mass index across Europe.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1357, doi. 10.1038/ng.3401
By:
- Mezzavilla, Massimo;
- Esko, Tonu;
- Powell, Joseph E;
- Kahali, Bratati;
- Pers, Tune H;
- Vedantam, Sailaja;
- Gasparini, Paolo;
- Werge, Thomas M;
- Boomsma, Dorret I;
- Chasman, Daniel I;
- de Geus, Eco J C;
- Hirschhorn, Joel N;
- Hottenga, Jouke Jan;
- Ingelsson, Erik;
- Loos, Ruth J F;
- North, Kari E;
- Goddard, Michael E;
- Yang, Jian;
- Visscher, Peter M;
- Robinson, Matthew R
Publication type:
Article
The genomic landscape of juvenile myelomonocytic leukemia.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1326, doi. 10.1038/ng.3400
By:
- Toretsky, Jeffrey A;
- Olshen, Adam B;
- Getz, Gad;
- Gruber, Tanja A;
- Golub, Todd R;
- Stegmaier, Kimberly;
- Loh, Mignon L;
- Stieglitz, Elliot;
- Chang, Tiffany Y;
- Gelston, Laura C;
- Esquivel, Emilio;
- Yu, Ariel;
- Archambeault, Sophie L;
- Beckman, Kyle;
- Cooper, Todd;
- Dahl, Gary V;
- Emanuel, Peter D;
- Liu, Y Lucy;
- Fluchel, Mark N;
- Goyal, Rakesh K
Publication type:
Article
Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1264, doi. 10.1038/ng.3307
By:
- Sidore, Carlo;
- Busonero, Fabio;
- Maschio, Andrea;
- Mulas, Antonella;
- Porcu, Eleonora;
- Pistis, Giorgio;
- Angius, Andrea;
- Moi, Paolo;
- Thein, Swee Lay;
- Galanello, Renzo;
- Cucca, Francesco;
- Danjou, Fabrice;
- Zoledziewska, Magdalena;
- Steri, Maristella;
- Perseu, Lucia;
- Pitzalis, Maristella;
- Pala, Mauro;
- Uda, Manuela;
- Sanna, Serena;
- Barella, Susanna
Publication type:
Article
An atlas of genetic correlations across human diseases and traits.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1236, doi. 10.1038/ng.3406
By:
- Bulik-Sullivan, Brendan;
- Anttila, Verneri;
- Gusev, Alexander;
- Loh, Po-Ru;
- Duncan, Laramie;
- Robinson, Elise B;
- Daly, Mark J;
- Price, Alkes L;
- Neale, Benjamin M;
- Finucane, Hilary K;
- Day, Felix R;
- Perry, John R B;
- Patterson, Nick
Publication type:
Article
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1334, doi. 10.1038/ng.3420
By:
- Caye, Aurélie;
- Strullu, Marion;
- Cassinat, Bruno;
- Gazal, Steven;
- Lainey, Elodie;
- Lachenaud, Julie;
- Vivent, Jocelyne;
- Verger, Emmanuelle;
- Vidaud, Dominique;
- Picard, Capucine;
- Dalle, Jean-Hugues;
- Baruchel, André;
- Chomienne, Christine;
- Cavé, Hélène;
- Guidez, Fabien;
- Méchinaud, Françoise;
- Adjaoud, Dalila;
- Paillard, Catherine;
- Nelken, Brigitte;
- Reguerre, Yves
Publication type:
Article
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1272, doi. 10.1038/ng.3368
By:
- Sidore, Carlo;
- Busonero, Fabio;
- Maschio, Andrea;
- Porcu, Eleonora;
- Mulas, Antonella;
- Pistis, Giorgio;
- Berutti, Riccardo;
- Gasparini, Paolo;
- Soranzo, Nicole;
- Angius, Andrea;
- Cucca, Francesco;
- Naitza, Silvia;
- Zoledziewska, Magdalena;
- Steri, Maristella;
- Danjou, Fabrice;
- Pitzalis, Maristella;
- Sanna, Serena;
- Timpson, Nicholas J;
- Toniolo, Daniela;
- Malerba, Giovanni
Publication type:
Article
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1294, doi. 10.1038/ng.3412
By:
- Lunetta, Kathryn L;
- Pervjakova, Natalia;
- Chasman, Daniel I;
- Stolk, Lisette;
- Finucane, Hilary K;
- Bulik-Sullivan, Brendan;
- Esko, Tõnu;
- He, Chunyan;
- Altmaier, Elisabeth;
- Huffman, Jennifer E;
- Porcu, Eleonora;
- Vuckovic, Dragana;
- Corre, Tanguy;
- Mangino, Massimo;
- Smith, Albert V;
- Andrulis, Irene L;
- Barbieri, Caterina;
- Benitez, Javier;
- Boerwinkle, Eric;
- Bojesen, Stig E
Publication type:
Article
Integrated molecular analysis of adult T cell leukemia/lymphoma.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1304, doi. 10.1038/ng.3415
By:
- Sanada, Masashi;
- Shibata, Tatsuhiro;
- Kataoka, Keisuke;
- Nagata, Yasunobu;
- Sato-Otsubo, Aiko;
- Kotani, Shinichi;
- Watatani, Yosaku;
- Takeda, June;
- Suzuki, Hiromichi;
- Sato, Yusuke;
- Shiozawa, Yusuke;
- Yoshizato, Tetsuichi;
- Yoshida, Kenichi;
- Makishima, Hideki;
- Ogawa, Seishi;
- Iwanaga, Masako;
- Nosaka, Kisato;
- Hishizawa, Masakatsu;
- Takaori-Kondo, Akifumi;
- Itonaga, Hidehiro
Publication type:
Article
Small island, big genetic discoveries.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1224, doi. 10.1038/ng.3426
By:
- Lettre, Guillaume;
- Hirschhorn, Joel N
Publication type:
Article
Intron retention is a widespread mechanism of tumor-suppressor inactivation.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1242, doi. 10.1038/ng.3414
By:
- Jung, Hyunchul;
- Lee, Donghoon;
- Lee, Jongkeun;
- Park, Donghyun;
- Kim, Yeon Jeong;
- Park, Woong-Yang;
- Hong, Dongwan;
- Park, Peter J;
- Lee, Eunjung
Publication type:
Article
Genomic landscapes of breast fibroepithelial tumors.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1341, doi. 10.1038/ng.3409
By:
- Tan, Jing;
- Ong, Choon Kiat;
- Lim, Weng Khong;
- Ng, Cedric Chuan Young;
- Rajasegaran, Vikneswari;
- Myint, Swe Swe;
- Nagarajan, Sanjanaa;
- Thangaraju, Saranya;
- Wijaya, Giovani Claresta;
- Lim, Jing Quan;
- Huang, Dachuan;
- Li, Zhimei;
- Yong, Wei Sean;
- Madhukumar, Preetha;
- Ho, Gay Hui;
- Tan, Veronique Kiak Mien;
- Wong, Chow Yin;
- Hartman, Mikael;
- Ong, Kong Wee;
- Tan, Benita K T
Publication type:
Article
Partitioning heritability by functional annotation using genome-wide association summary statistics.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1228, doi. 10.1038/ng.3404
By:
- Finucane, Hilary K;
- Bulik-Sullivan, Brendan;
- Trynka, Gosia;
- Anttila, Verneri;
- Farh, Kyle;
- Ripke, Stephan;
- Purcell, Shaun;
- Okada, Yukinori;
- Raychaudhuri, Soumya;
- Daly, Mark J;
- Neale, Benjamin M;
- Price, Alkes L;
- Gusev, Alexander;
- Loh, Po-Ru;
- Lindstrom, Sara;
- Reshef, Yakir;
- Xu, Han;
- Zang, Chongzhi;
- Day, Felix R;
- Perry, John R B
Publication type:
Article