Works matching IS 1021335X AND DT 2016 AND VI 35 AND IP 2

Results: 74

CORRIGENDUM: Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1222, doi. 10.3892/or.2015.4438

By:

Yitao Jia;
Suqiao Zhang;
Lingling Miao;
Jingbao Wang;
Zujian Jin;
Bin Gu;
Zhihui Duan;
Zhaolong Zhao;
Shunmao Ma;
Wenjin Zhang;
Zhongxin Li

Publication type:

Article

Uvangoletin induces mitochondria-mediated apoptosis in HL-60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1213, doi. 10.3892/or.2015.4443

By:

ZHUANZHEN ZHENG;
ZHENHUA QIAO;
RONG GONG;
YALIN WANG;
YIQUN ZHANG;
YANPING MA;
LI ZHANG;
YUJIN LU;
BO JIANG;
GUOXIA LI;
CHUNXIA DONG;
WENLIANG CHEN

Publication type:

Article

Tripartite motif 16 suppresses breast cancer stem cell properties through regulation of Gli-1 degradation via the ubiquitin-proteasome pathway.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1204, doi. 10.3892/or.2015.4437

By:

JUNTAO YAO;
TAO XU;
TAO TIAN;
XIAO FU;
WENJUAN WANG;
SUONI LI;
TINGTING SHI;
AILI SUO;
ZHIPING RUAN;
HUI GUO;
YU YAO

Publication type:

Article

RSPH9 methylation pattern as a prognostic indicator in patients with non-muscle invasive bladder cancer.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1195, doi. 10.3892/or.2015.4409

By:

HYUNG-YOON YOON;
YONG-JUNE KIM;
JI SANG KIM;
YOUNG-WON KIM;
HO WON KANG;
WON TAE KIM;
SEOK-JOONG YUN;
KEUN HO RYU;
SANG-CHEOL LEE;
WUN-JAE KIM

Publication type:

Article

JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1186, doi. 10.3892/or.2015.4410

By:

SUNG KYUNG CHOI;
SEONG HWI HONG;
HYUK SOON KIM;
CHAN YOUNG SHIN;
SUK WOO NAM;
WAHN SOO CHOI;
JEUNG-WHAN HAN;
JUENG SOO YOU

Publication type:

Article

Expression and purification of recombinant ATF-mellitin, a new type fusion protein targeting ovarian cancer cells, in P. pastoris.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1179, doi. 10.3892/or.2015.4448

By:

MANMAN SU;
WEIQIN CHANG;
KUN ZHANG;
MANHUA CUI;
SHUYING WU;
TIANMIN XU

Publication type:

Article

miR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1170, doi. 10.3892/or.2015.4412

By:

YUNHUI HU;
KAIYONG LI;
ASADUZZAMAN, MUHAMMAD;
CUELLA, RAQUEL;
HUI SHI;
RAGUZ, SELINA;
COOMBES, RAOUL CHARLES;
YUAN ZHOU;
YAGüE, ERNESTO

Publication type:

Article

Activation of Tax protein by c-Jun-N-terminal kinase is not dependent on the presence or absence of the early growth response-1 gene product.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1163, doi. 10.3892/or.2015.4424

By:

PARRA, EDUARDO;
GUTIERRéZ, LUíS;
FERREIRA, JORGE

Publication type:

Article

CX3CL1 increases invasiveness and metastasis by promoting epithelial-to-mesenchymal transition through the TACE/TGF-α/EGFR pathway in hypoxic androgen-independent prostate cancer cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1153, doi. 10.3892/or.2015.4470

By:

JIEBING TANG;
LIJIE XIAO;
RONGJUN CUI;
DONG LI;
XIULAN ZHENG;
LIJUAN ZHU;
HUI SUN;
YUJIA PAN;
YANDAN DU;
XIAOGUANG YU

Publication type:

Article

Direct binding of Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1147, doi. 10.3892/or.2015.4472

By:

HYE YOUNG CHOI;
NAMMI PARK;
JAE BOEM NA;
EUN SOOK KO;
PARK, JAE-YONG;
JAE CHEAL YOO

Publication type:

Article

Integrated analysis of the miRNA, gene and pathway regulatory network in gastric cancer.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1135, doi. 10.3892/or.2015.4451

By:

HAI YANG ZHANG;
YANJUN QU;
JINGJING DUAN;
TING DENG;
RUI LIU;
LE ZHANG;
MING BAI;
JIAL U LI;
LIK UN ZHOU;
TAO NING;
HONGLI LI;
SHA OHUA GE;
HUA LI;
GUOGUANG YING;
DINGZHI HUANG;
YI BA

Publication type:

Article

MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-β1.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1125, doi. 10.3892/or.2015.4432

By:

QIZHUANG LI;
QUAN CHENG;
ZIGUI CHEN;
RENJUN PENG;
RUI CHEN;
ZHIMING MA;
XIN WAN;
JINCAN LIU;
MING MENG;
ZHIGANG PENG;
BING JIANG

Publication type:

Article

Suppression of nucleosome-binding protein 1 by miR-326 impedes cell proliferation and invasion in non-small cell lung cancer cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1117, doi. 10.3892/or.2015.4403

By:

DONGFAN LI;
XUSHENG DU;
AN LIU;
PENG LI

Publication type:

Article

β-lapachone suppresses the proliferation of human malignant melanoma cells by targeting specificity protein 1.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1109, doi. 10.3892/or.2015.4439

By:

WOONG BANG;
YOUNG-JOO JEON;
JIN HYOUNG CHO;
RA HAM LEE;
PARK, SEON-MIN;
JAE-CHEON SHIN;
NAG-JIN CHOI;
YUNG HYUN CHOI;
JUNG-JAE CHO;
JAE-MIN SEO;
SEUNG-YEOP LEE;
JUNG-HYUN SHIM;
JUNG-IL CHAE

Publication type:

Article

Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1101, doi. 10.3892/or.2015.4447

By:

LEI GAO;
ZHEN XU;
YAN WANG;
BIN SUN;
ZHICHENG SONG;
BINING YANG;
XU LIU;
YUAN LIN;
JINYONG PENG;
GUOZHU HAN;
SHISHENG WANG;
ZEYAO TANG

Publication type:

Article

Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1091, doi. 10.3892/or.2015.4457

By:

YOUSEF, BASHIR A.;
GUERRAM, MOUNIA;
HASSAN, HOZEIFA M.;
HAMDI, AIDA M.;
LU-YONG ZHANG;
ZHEN-ZHOU JIANG

Publication type:

Article

Reciprocal negative feedback loop between EZH2 and miR-101-1 contributes to miR-101 deregulation in hepatocellular carcinoma.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1083, doi. 10.3892/or.2015.4467

By:

DA HUANG;
XIAOBEI WANG;
CHUNBO ZHUANG;
WUHE SHI;
MU LIU;
QIMING TU;
DETAI ZHANG;
LIHUA HU

Publication type:

Article

miR-331-3p inhibits proliferation and promotes apoptosis by targeting HER2 through the PI3K/Akt and ERK1/2 pathways in colorectal cancer.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1075, doi. 10.3892/or.2015.4450

By:

DONGLI ZHAO;
YANXIA SUI;
XIAOQIANG ZHENG

Publication type:

Article

Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1065, doi. 10.3892/or.2015.4413

By:

GUANGMING ZHAO;
XIAODONG HAN;
SIWEN ZHENG;
ZHEN LI;
YANG SHA;
JING NI;
ZHE SUN;
SONG QIAO;
ZHIQI SONG

Publication type:

Article

miR-506 functions as a tumor suppressor in glioma by targeting STAT3.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1057, doi. 10.3892/or.2015.4406

By:

TAO PENG;
LIXIANG ZHOU;
LING ZUO;
YONGXIN LUAN

Publication type:

Article

Cul1 promotes melanoma cell proliferation by promoting DEPTOR degradation and enhancing cap-dependent translation.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1049, doi. 10.3892/or.2015.4442

By:

LAN CHEN;
TIANYU LIU;
YUNHUA TU;
DONGYUN RONG;
YU CAO

Publication type:

Article

MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1041, doi. 10.3892/or.2015.4408

By:

BOH-RAM KIM;
SEUNG-HOON LEE;
MI-SUN PARK;
SEUNG-HEE SEO;
YOUNG-MIN PARK;
YOUNG-JOO KWON;
SEUNG-BAE RHO

Publication type:

Article

Ginkgetin exerts growth inhibitory and apoptotic effects on osteosarcoma cells through inhibition of STAT3 and activation of caspase-3/9.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1034, doi. 10.3892/or.2015.4427

By:

MIN XIONG;
LIN WANG;
HUA-LONG YU;
HENG HAN;
DAN MAO;
JIE CHEN;
YUN ZENG;
NING HE;
ZHI-GANG LIU;
ZHI-YONG WANG;
SHOU-JIA XU;
LE-YUN GUO;
YONG-AN WANG

Publication type:

Article

Aberrant GRK6 promoter methylation is associated with poor prognosis in hypopharyngeal squamous cell carcinoma.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1027, doi. 10.3892/or.2015.4469

By:

XIAOXIA QIU;
JIANQIU CHEN;
ZHENXIN ZHANG;
YIWEN YOU;
ZHIWEI WANG

Publication type:

Article

Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1020, doi. 10.3892/or.2015.4440

By:

JI-HUN KIM;
YU CHUL KIM;
BYOUN GDUCK PARK

Publication type:

Article

Pro-apoptotic effects of splice-switching oligonucleotides targeting Bcl-x pre-mRNA in human glioma cell lines.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1013, doi. 10.3892/or.2015.4465

By:

ZHAOHUI LI;
QINGWEI LI;
LIANG HAN;
NAN TIAN;
QIANLEI LIANG;
YANZHE LI;
XINGLI ZHAO;
CHAO DU;
YU TIAN

Publication type:

Article

FZD2 inhibits the cell growth and migration of salivary adenoid cystic carcinomas.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 1006, doi. 10.3892/or.2015.3811

By:

LIN-CAN DING;
XIAO-YU HUANG;
FEI-FEI ZHENG;
JIAN XIE;
LIN SHE;
YAN FENG;
BO-HUA SU;
DA-LI ZHENG;
YOU-GUANG LU

Publication type:

Article

An integrated analysis of cancer genes in thyroid cancer.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 962, doi. 10.3892/or.2015.4466

By:

LI CHAI;
JIA LI;
ZHONGWEI LV

Publication type:

Article

Hypoxia inducible factor-1 mediates upregulation of urokinase-type plasminogen activator receptor gene transcription during hypoxia in cervical cancer cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 992, doi. 10.3892/or.2015.4449

By:

HIROTAKA NISHI;
TORU SASAKI;
YUZO NAGAMITSU;
FUMITOSHI TERAUCHI;
TAKESHI NAGAI;
TOSHITAKA NAGAO;
KEIICHI ISAKA

Publication type:

Article

Study on the inhibition of hyperthermic CO2 pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 985, doi. 10.3892/or.2015.4446

By:

JIAYING ZHAO;
YUANKUN CAI;
CHENQING YIN;
YOU LV;
WANMIN WEI;
XIN WANG;
ZONG HAO;
CHENXIA SHEN;
HUIPENG WANG;
JUN CHEN

Publication type:

Article

Magnetic gold nanoparticle-mediated small interference RNA silencing Bag-1 gene for colon cancer therapy.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 978, doi. 10.3892/or.2015.4453

By:

WENBAI HUANG;
ZHAN'AO LIU;
GUANZHOU ZHOU;
AILING TIAN;
NIANFENG SUN

Publication type:

Article

KIF1B promotes glioma migration and invasion via cell surface localization of MT1-MMP.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 971, doi. 10.3892/or.2015.4426

By:

SONGYU CHEN;
MINGZHI HAN;
WEILIANG CHEN;
YING HE;
BIN HUANG;
PENG ZHAO;
QIBING HUANG;
LIANG GAO;
XUN QU;
XINGANG LI

Publication type:

Article

CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 999, doi. 10.3892/or.2015.4462

By:

TAO XIANG;
FENG YU;
RUSHAN FEI;
JING QIAN;
WENBIN CHEN

Publication type:

Article

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 912, doi. 10.3892/or.2015.4434

By:

YING-ZI FU;
YUAN-YUAN YAN;
MIAO HE;
QING-HUAN XIAO;
WEI-FAN YAO;
LIN ZHAO;
HUI-ZHE WU;
ZHAO-JIN YU;
MING-YI ZHOU;
MU-TIAN LV;
SHAN-SHAN ZHANG;
JIAN-JUN CHEN;
MIN-JIE WEI

Publication type:

Article

Histone deacetylase 4 increases progressive epithelial ovarian cancer cells via repression of p21 on fibrillar collagen matrices.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 948, doi. 10.3892/or.2015.4423

By:

YU-FEI SHEN;
AI-MIN WEI;
QING KOU;
QIAO-YING ZHU;
LEI ZHANG

Publication type:

Article

BMP9/p38 MAPK is essential for the antiproliferative effect of resveratrol on human colon cancer.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 939, doi. 10.3892/or.2015.4407

By:

SHUANG-XUE YUAN;
DONG-XU WANG;
QIU-XIANG WU;
CHUN-MEI REN;
YANG LI;
QIAN-ZHAO CHEN;
YU-HUA ZENG;
YING SHAO;
JUN-QIN YANG;
YAN BAI;
PU ZHANG;
YU YU;
KE WU;
WEN-JUAN SUN;
BAI-CHENG HE

Publication type:

Article

Significance of TGFBR3 allelic loss in the deregulation of TGFβ signaling in primary human endometrial carcinomas.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 932, doi. 10.3892/or.2015.4400

By:

ZAKRZEWSKI, PIOTR K.;
NOWACKA-ZAWISZA, MARIA;
SEMCZUK, ANDRZEJ;
RECHBERGER, TOMASZ;
GAŁCZYŃSKI, KRZYSZTOF;
KRAJEWSKA, WANDA M.

Publication type:

Article

Downregulation of Bmi-1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem-like cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 923, doi. 10.3892/or.2015.4414

By:

XINHUA XU;
YANG LIU;
JIN SU;
DAOJUN LI;
JUAN HU;
QIAO HUANG;
MINGQIAN LU;
XIA OYAN LIU;
JINGHUA REN;
WEIHONG CHEN;
LIDAN SUN

Publication type:

Article

ERK signaling mediates long-term low concentration 3,3'-diindolylmethane inhibited nasopharyngeal carcinoma growth and metastasis: An in vitro and in vivo study.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 955, doi. 10.3892/or.2015.4428

By:

FEN LI;
CHEN CHEN;
SHI-MING CHEN;
BO-KUI XIAO;
ZE-ZHANG TAO

Publication type:

Article

Expression of LMP and EBNA genes in Epstein-Barr virus-associated lymphomas in Hu-PBL/SCID mice.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 905, doi. 10.3892/or.2015.4401

By:

YUNLIAN TANG;
SULI LU;
XIAONING GAN;
FANG LIU;
YANG ZHANG;
CHUNYAN LUO;
YUXIA PAN;
LI HONG;
RULIANG GAN

Publication type:

Article

Hispolon inhibits breast cancer cell migration by reversal of epithelial-to-mesenchymal transition via suppressing the ROS/ERK/Slug/E-cadherin pathway.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 896, doi. 10.3892/or.2015.4445

By:

ZHAO ZHAO;
YI-SHENG SUN;
WEI CHEN;
LONG-XIAN LV;
YONG-QUAN LI

Publication type:

Article

MicroRNA-340 inhibits prostate cancer cell proliferation and metastasis by targeting the MDM2-p53 pathway.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 887, doi. 10.3892/or.2015.4458

By:

KAI HUANG;
YUXIN TANG;
LEYE HE;
YINGBO DAI

Publication type:

Article

Digitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxel.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 878, doi. 10.3892/or.2015.4416

By:

YAKISICH, JUAN SEBASTIAN;
AZAD, NEELAM;
VENKATADRI, RAJKUMAR;
KULKARNI, YOGESH;
WRIGHT, CLAYTON;
KAUSHIK, VIVEK;
O'DOHERTY, GEORG E A.;
IYER, ANAND KRISHNAN V.

Publication type:

Article

miR-218-5p inhibits the stem cell properties and invasive ability of the A2B5+CD133- subgroup of human glioma stem cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 869, doi. 10.3892/or.2015.4418

By:

ZHIWU WU;
YONG HAN;
YANYAN LI;
XUETAO LI;
TING SUN;
GUILIN CHEN;
YULUN HUANG;
YOUXIN ZHOU;
ZIWEI DU

Publication type:

Article

Effects of curcumin on cancer cell mitochondrial function and potential monitoring with 18F-FDG uptake.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 861, doi. 10.3892/or.2015.4460

By:

KYUNG-HO JUNG;
JIN HEE LEE;
JIN WON PARK;
SEUNG-HWAN MOON;
YOUNG SEOK CHO;
YEARN SEONG CHOE;
KYUNG-HAN LEE

Publication type:

Article

Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 851, doi. 10.3892/or.2015.4452

By:

JITSUKO TAKANO;
ASAHIRO MORISHITA;
SHINTARO FUJIHARA;
HISAKAZU IWAMA;
FUYUKO KOKADO;
KEIKO FUJIKAWA;
KOJI FUJITA;
TAIGA CHIYO;
TOMOKO TADOKORO;
TEPPEI SAKAMOTO;
TAKAKO NOMURA;
JOJI TANI;
HISAAKI MIYOSHI;
HIROHITO YONEYAMA;
HIDEKI KOBARA;
HIROHITO MORI;
TOSHIHIRO NIKI;
MITSUOMI HIRASHIMA;
TSUTOMU MASAKI

Publication type:

Article

Identification of novel therapeutic targets in the secretome of ionizing radiation-induced senescent tumor cells.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 841, doi. 10.3892/or.2015.4473

By:

HYUN JUNG HWANG;
SEUNG HEE JUNG;
HYUNG CHUL LEE;
NA KYUNG HAN;
IN HWA BAE;
MINYOUNG LEE;
YOUNG-HOON HAN;
YOUNG-SUN KANG;
SU-JAE LEE;
HEON JOO PARK;
YOUNG-GYU KO;
JAE-SEON LEE

Publication type:

Article

Isoalantolactone induces autophagic cell death in SKOV3 human ovarian carcinoma cells via upregulation of PEA-15.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 833, doi. 10.3892/or.2015.4461

By:

ZHIYONG WENG;
HONGGUO GAO;
JIEHUA HU;
YONGGANG FAN;
HONGYAN WANG;
LIHUA LI

Publication type:

Article

Luteolin suppresses development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 825, doi. 10.3892/or.2015.4431

By:

COOK, MATTHEW T.;
MAFUVADZE, BENFORD;
BESCH-WILLIFORD, CYNTHIA;
ELLERSIECK, MARK R.;
GOYETTE, SANDY;
HYDER, SALMAN M.

Publication type:

Article

Expression of prion protein is closely associated with pathological and clinical progression and abnormalities of p53 in head and neck squamous cell carcinomas.

Published in:

Oncology Reports, 2016, v. 35, n. 2, p. 817, doi. 10.3892/or.2015.4425

By:

WEI WEI;
QI SHI;
NAI-SONG ZHANG;
KAN GXIAO;
LI-NA CHEN;
XIAO-DONG YANG;
JIA-FU JI;
XIAO-PING DONG

Publication type:

Article