Works matching IS 09646906 AND DT 2018 AND VI 27 AND IP 16

Results: 13

TSPO–PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington’s disease: preclinical evidence with the p75NTR ligand LM11A-31.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2893, doi. 10.1093/hmg/ddy202

By:

Simmons, Danielle A;
James, Michelle L;
Belichenko, Nadia P;
Semaan, Sarah;
Condon, Christina;
Kuan, Jason;
Shuhendler, Adam J;
Miao, Zheng;
Chin, Frederick T;
Longo, Frank M

Publication type:

Article

Temporal and tissue-specific variability of SMN protein levels in mouse models of spinal muscular atrophy.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2851, doi. 10.1093/hmg/ddy195

By:

Groen, Ewout J N;
Perenthaler, Elena;
Courtney, Natalie L;
Jordan, Crispin Y;
Shorrock, Hannah K;
van der Hoorn, Dinja;
Huang, Yu-Ting;
Murray, Lyndsay M;
Viero, Gabriella;
Gillingwater, Thomas H

Publication type:

Article

The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2913, doi. 10.1093/hmg/ddy204

By:

Gonzalez, David;
Rebolledo, Daniela L;
Correa, Lina M;
Court, Felipe A;
Cerpa, Waldo;
Lipson, Kenneth E;
Zundert, Brigitte van;
Brandan, Enrique

Publication type:

Article

Regulation of the neuropathy-associated Pmp22 gene by a distal super-enhancer.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2830, doi. 10.1093/hmg/ddy191

By:

Pantera, Harrison;
Moran, John J;
Hung, Holly A;
Pak, Evgenia;
Dutra, Amalia;
Svaren, John

Publication type:

Article

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2874, doi. 10.1093/hmg/ddy201

By:

Tapias, Victor;
Jainuddin, Shari;
Ahuja, Manuj;
Stack, Cliona;
Elipenahli, Ceyhan;
Vignisse, Julie;
Gerges, Meri;
Starkova, Natalia;
Xu, Hui;
Starkov, Anatoly A

Publication type:

Article

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2863, doi. 10.1093/hmg/ddy200

By:

Bondar, Vitaliy V;
Adamski, Carolyn J;
Onur, Tarik S;
Tan, Qiumin;
Wang, Li;
Diaz-Garcia, Javier;
Park, Jeehye;
Orr, Harry T;
Botas, Juan;
Zoghbi, Huda Y

Publication type:

Article

Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2805, doi. 10.1093/hmg/ddy189

By:

Lee, Kwan Young;
Jewett, Kathryn A;
Chung, Hee Jung;
Tsai, Nien-Pei

Publication type:

Article

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2927, doi. 10.1093/hmg/ddy206

By:

Partida, Gabriel Cuellar;
Laurin, Charles;
Ring, Susan M;
Gaunt, Tom R;
McRae, Allan F;
Visscher, Peter M;
Montgomery, Grant W;
Martin, Nicholas G;
Hemani, Gibran;
Suderman, Matthew

Publication type:

Article

A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2817, doi. 10.1093/hmg/ddy185

By:

Barzilai-Tutsch, Hila;
Dewulf, Melissa;
Lamaze, Christophe;
Browne, Gillian Butler;
Pines, Mark;
Halevy, Orna

Publication type:

Article

DNA methylation and inflammation marker profiles associated with a history of depression.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2840, doi. 10.1093/hmg/ddy199

By:

Crawford, Bethany;
Craig, Zoe;
Mansell, Georgina;
White, Isobel;
Smith, Adam;
Spaull, Steve;
Imm, Jennifer;
Hannon, Eilis;
Wood, Andrew;
Yaghootkar, Hanieh

Publication type:

Article

Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2789, doi. 10.1093/hmg/ddy192

By:

Morriss, Ginny R;
Rajapakshe, Kimal;
Huang, Shixia;
Coarfa, Cristian;
Cooper, Thomas A

Publication type:

Article

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2940, doi. 10.1093/hmg/ddy211

By:

Kocarnik, Jonathan M;
Richard, Melissa;
Graff, Misa;
Haessler, Jeffrey;
Bien, Stephanie;
Carlson, Chris;
Carty, Cara L;
Reiner, Alexander P;
Avery, Christy L;
Ballantyne, Christie M

Publication type:

Article

Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2775, doi. 10.1093/hmg/ddy168

By:

Vos, Ivo J H M de;
Tao, Evelyn Yaqiong;
Ong, Sheena Li Ming;
Goggi, Julian L;
Scerri, Thomas;
Wilson, Gabrielle R;
Low, Chernis Guai Mun;
Wong, Arnette Shi Wei;
Grussu, Dominic;
Stegmann, Alexander P A

Publication type:

Article