Works matching IS 08990042 AND DT 2007 AND VI 19 AND IP 9

Results: 9
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    Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—Building chiral technology toolboxesIn contrast to previous usage, Chiral Technology is defined in this review as the use of techniques or tools for the determination of absolute stereochemistry, the chiral analysis or preparative separation of racemic small molecules containing one or more asymmetric centers into (all of) their enantiomers (= enantiomeric or chiral separation), and the facilitation of asymmetric transformations, but not asymmetric transformations themselves. The terms Chiral Technology and Chirotechnology have often been used as a general category for asymmetric transformations using enzymes, chiral building blocks, chiral auxiliaries, and chiral catalysts, as well as chiral salt resolution.1–13

    Published in:
    Chirality, 2007, v. 19, n. 9, p. 658
    By:
    • Oliver McConnell;
    • Alvin Bach;
    • Carl Balibar;
    • Neal Byrne;
    • Yanxuan Cai;
    • Guy Carter;
    • Michael Chlenov;
    • Li Di;
    • Kristi Fan;
    • Igor Goljer;
    • Yanan He;
    • Don Herold;
    • Michael Kagan;
    • Edward Kerns;
    • Frank Koehn;
    • Christina Kraml;
    • Vasilios Marathias;
    • Brian Marquez;
    • Leonard McDonald;
    • Lisa Nogle
    Publication type:
    Article
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