Works matching IS 08936692 AND DT 1996 AND VI 28 AND IP 4
Results: 27
Introduction: State of the art in transgenic animals in mutation research.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 295, doi. 10.1002/(SICI)1098-2280(1996)28:4<295::AID-EM1>3.0.CO;2-B
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System issue: Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacl transgene in the Big Blue® Rat-2 embryo cell line.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 325, doi. 10.1002/(SICI)1098-2280(1996)28:4<325::AID-EM5>3.0.CO;2-A
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Masthead.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. fmi, doi. 10.1002/1098-2280(1996)28:4<::AID-EM2850280401>3.0.CO;2-W
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System issues: Evaluation of the in vivo genotoxic potential of three carcinogenic aromatic amines using the Big Blue™ transgenic mouse mutation assay.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 354, doi. 10.1002/(SICI)1098-2280(1996)28:4<354::AID-EM9>3.0.CO;2-B
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System Issues: Mutagenic response of the endogenous hprt gene and lacl transgene in benzo[a]pyrene-treated Big Blue™ B6C3F1 mice.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 376, doi. 10.1002/(SICI)1098-2280(1996)28:4<376::AID-EM11>3.0.CO;2-C
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Other transgenic mutation assays: Parameters affecting the use of the lac repressor system in eukaryotic cells and transgenic animals.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 447, doi. 10.1002/(SICI)1098-2280(1996)28:4<447::AID-EM22>3.0.CO;2-E
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Mutational specificity: Mutational spectra in transgenic animal research: Data analysis and study design based upon the mutant or mutation frequency.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 405, doi. 10.1002/(SICI)1098-2280(1996)28:4<405::AID-EM15>3.0.CO;2-J
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Other transgenic mutation assays: Development of a novel mouse tk<sup>+/−</sup> embryonic stem cell line for use in mutagenicity studies.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 483, doi. 10.1002/(SICI)1098-2280(1996)28:4<483::AID-EM26>3.0.CO;2-A
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Mutational specificity: Mutational spectra of tamoxifen-induced mutations in the livers of lacl transgenic rats.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 430, doi. 10.1002/(SICI)1098-2280(1996)28:4<430::AID-EM19>3.0.CO;2-G
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System issues: Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 317, doi. 10.1002/(SICI)1098-2280(1996)28:4<317::AID-EM4>3.0.CO;2-8
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System issues: Organ variation in the mutagenicity of dimethylnitrosamine in Big Blue® mice.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 348, doi. 10.1002/(SICI)1098-2280(1996)28:4<348::AID-EM8>3.0.CO;2-7
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System Issues: Organ variation in the mutagenicity of ethylnitrosourea in Muta™ Mouse: Results of the collaborative study on the transgenic mutation assay by JEMS/MMS.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 363, doi. 10.1002/(SICI)1098-2280(1996)28:4<363::AID-EM10>3.0.CO;2-D
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Prospects for safety testing: Initial consideration for use of transgenic mutation assays in a regulatory submission.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 443, doi. 10.1002/(SICI)1098-2280(1996)28:4<443::AID-EM21>3.0.CO;2-E
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Mutational specificity: Database and software for the analysis of mutations at the lacl gene in both transgenic rodents and bacteria.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 397, doi. 10.1002/(SICI)1098-2280(1996)28:4<397::AID-EM14>3.0.CO;2-A
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Other transgenic mutation assays: APRT: A versatile in vivo resident reporter of local mutation and loss of heterozygosity.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 471, doi. 10.1002/(SICI)1098-2280(1996)28:4<471::AID-EM25>3.0.CO;2-B
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Mutational specificity: Assessment of 1,3-butadiene mutagenicity in the bone marrow of B6C3F1 lacl transgenic mice (Big Blue®): A review of mutational spectrum and LACL mutant frequency after a 5-day 625 PPM 1,3-butadiene exposure.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 424, doi. 10.1002/(SICI)1098-2280(1996)28:4<424::AID-EM18>3.0.CO;2-H
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System issues: A test for neutrality of mutations of the lacZ transgene.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 313, doi. 10.1002/(SICI)1098-2280(1996)28:4<313::AID-EM3>3.0.CO;2-C
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System issues: Mutagenic response to benzene and Tris(2,3-dibromopropyl)-phosphate in the lambda lacl transgenic mouse mutation assay: A standardized approach to in vivo mutation analysis.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 342, doi. 10.1002/(SICI)1098-2280(1996)28:4<342::AID-EM7>3.0.CO;2-D
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Prospects for safety testing: A strategy for the application of transgenic rodent mutagenesis assays.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 434, doi. 10.1002/(SICI)1098-2280(1996)28:4<434::AID-EM20>3.0.CO;2-F
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Mutational specificity: An efficient laboratory protocol for the sequencing of large numbers of lacl mutants recovered from Big Blue® transgenic animals.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 393, doi. 10.1002/(SICI)1098-2280(1996)28:4<393::AID-EM13>3.0.CO;2-A
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Other transgenic mutation assays: A new transgenic mouse mutagenesis test system using Spi<sup>−</sup> and 6-thioguanine selections.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 465, doi. 10.1002/(SICI)1098-2280(1996)28:4<465::AID-EM24>3.0.CO;2-C
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Mutational specificity: Spectrum of mutations in kidney, stomach, and liver from lacl transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 418, doi. 10.1002/(SICI)1098-2280(1996)28:4<418::AID-EM17>3.0.CO;2-I
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System issues: Spontaneous mutation in Big Blue® transgenic mice: Analysis of age, gender, and tissue type.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 299, doi. 10.1002/(SICI)1098-2280(1996)28:4<299::AID-EM2>3.0.CO;2-7
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System issues: Why do stem cells exist?
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 334, doi. 10.1002/(SICI)1098-2280(1996)28:4<334::AID-EM6>3.0.CO;2-B
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System issues: The genetic analysis of lacl mutations in sectored plaques from Big Blue® transgenic mice.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 385, doi. 10.1002/(SICI)1098-2280(1996)28:4<385::AID-EM12>3.0.CO;2-B
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Mutational specificity: Mutation frequencies but not mutant frequencies in Big Blue® mice fit a Poisson distribution.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 414, doi. 10.1002/(SICI)1098-2280(1996)28:4<414::AID-EM16>3.0.CO;2-I
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Other transgenic mutation assays: Tissue specificity of spontaneous point mutations in λsupF transgenic mice.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 459, doi. 10.1002/(SICI)1098-2280(1996)28:4<459::AID-EM23>3.0.CO;2-D
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