Works matching IS 08876924 AND DT 2015 AND VI 29 AND IP 4

Results: 36

Clonal origins of ETV6-RUNX1⁺ acute lymphoblastic leukemia: studies in monozygotic twins.

Published in:

2015

By:

Alpar, D;
Wren, D;
Ermini, L;
Mansur, M B;
van Delft, F W;
Bateman, C M;
Titley, I;
Kearney, L;
Szczepanski, T;
Gonzalez, D;
Ford, A M;
Potter, N E;
Greaves, M

Publication type:

journal article

Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-[kappa]B pathway activation but not with poor prognosis.

Published in:

2015

By:

Poglio, S;
Cahu, X;
Uzan, B;
Besnard-Guérin, C;
Lapillonne, H;
Leblanc, T;
Baruchel, A;
Landman-Parker, J;
Petit, A;
Baleydier, F;
Amsellem, S;
Baud, V;
Ballerini, P;
Pflumio, F

Publication type:

Journal Article

The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma.

Published in:

2015

By:

Ferretti, E;
Tripodo, C;
Pagnan, G;
Guarnotta, C;
Marimpietri, D;
Corrias, M V;
Ribatti, D;
Zupo, S;
Fraternali-Orcioni, G;
Ravetti, J L;
Pistoia, V;
Corcione, A

Publication type:

journal article

Anti-CD20 therapy induces a memory Th1 response through the IFN-γ/IL-12 axis and prevents protumor regulatory T-cell expansion in mice.

Published in:

2015

By:

Deligne, C;
Metidji, A;
Fridman, W-H;
Teillaud, J-L

Publication type:

journal article

Functional characterization of BTK(C481S) mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors.

Published in:

2015

By:

Cheng, S;
Guo, A;
Lu, P;
Ma, J;
Coleman, M;
Wang, Y L

Publication type:

journal article

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 788, doi. 10.1038/leu.2014.246

By:

Fei, F;
Lim, M;
George, A A;
Kirzner, J;
Lee, D;
Seeger, R;
Groffen, J;
Abdel-Azim, H;
Heisterkamp, N

Publication type:

Article

Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 783, doi. 10.1038/leu.2014.247

By:

Kamel, S;
Horton, L;
Ysebaert, L;
Levade, M;
Burbury, K;
Tan, S;
Cole-Sinclair, M;
Reynolds, J;
Filshie, R;
Schischka, S;
Khot, A;
Sandhu, S;
Keating, M J;
Nandurkar, H;
Tam, C S

Publication type:

Article

Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 981, doi. 10.1038/leu.2014.320

By:

Huelsemann, M F;
Patz, M;
Beckmann, L;
Brinkmann, K;
Otto, T;
Fandrey, J;
Becker, H J;
Theurich, S;
von Bergwelt-Baildon, M;
Pallasch, C P;
Zahedi, R P;
Kashkar, H;
Reinhardt, H C;
Hallek, M;
Wendtner, C M;
Frenzel, L P

Publication type:

Article

Immunosuppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern Cooperative Oncology Group (E5998).

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 886, doi. 10.1038/leu.2014.298

By:

Loughran, T P;
Zickl, L;
Olson, T L;
Wang, V;
Zhang, D;
Rajala, H L M;
Hasanali, Z;
Bennett, J M;
Lazarus, H M;
Litzow, M R;
Evens, A M;
Mustjoki, S;
Tallman, M S

Publication type:

Article

A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 807, doi. 10.1038/leu.2014.296

By:

Zhou, L;
Zhang, Y;
Chen, S;
Kmieciak, M;
Leng, Y;
Lin, H;
Rizzo, K A;
Dumur, C I;
Ferreira-Gonzalez, A;
Dai, Y;
Grant, S

Publication type:

Article

Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 819, doi. 10.1038/leu.2014.299

By:

Tursky, M L;
Beck, D;
Thoms, J A I;
Huang, Y;
Kumari, A;
Unnikrishnan, A;
Knezevic, K;
Evans, K;
Richards, L A;
Lee, E;
Morris, J;
Goldberg, L;
Izraeli, S;
Wong, J W H;
Olivier, J;
Lock, R B;
MacKenzie, K L;
Pimanda, J E

Publication type:

Article

Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 869, doi. 10.1038/leu.2014.289

By:

Engle, E K;
Fisher, D A C;
Miller, C A;
McLellan, M D;
Fulton, R S;
Moore, D M;
Wilson, R K;
Ley, T J;
Oh, S T

Publication type:

Article

Novel drugs for older patients with acute myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 760, doi. 10.1038/leu.2014.244

By:

Montalban-Bravo, G;
Garcia-Manero, G

Publication type:

Article

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 798, doi. 10.1038/leu.2014.276

By:

Mets, E;
Van der Meulen, J;
Van Peer, G;
Boice, M;
Mestdagh, P;
Van de Walle, I;
Lammens, T;
Goossens, S;
De Moerloose, B;
Benoit, Y;
Van Roy, N;
Clappier, E;
Poppe, B;
Vandesompele, J;
Wendel, H-G;
Taghon, T;
Rondou, P;
Soulier, J;
Van Vlierberghe, P;
Speleman, F

Publication type:

Article

Dual PI3K/mTOR inhibition shows antileukemic activity in MLL-rearranged acute myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 828, doi. 10.1038/leu.2014.305

By:

Sandhöfer, N;
Metzeler, K H;
Rothenberg, M;
Herold, T;
Tiedt, S;
Groiß, V;
Carlet, M;
Walter, G;
Hinrichsen, T;
Wachter, O;
Grunert, M;
Schneider, S;
Subklewe, M;
Dufour, A;
Fröhling, S;
Klein, H-G;
Hiddemann, W;
Jeremias, I;
Spiekermann, K

Publication type:

Article

Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 901, doi. 10.1038/leu.2014.287

By:

Steger, J;
Füller, E;
Garcia-Cuellar, M-P;
Hetzner, K;
Slany, R K

Publication type:

Article

Anti-CD20 therapy induces a memory Th1 response through the IFN-γ/IL-12 axis and prevents protumor regulatory T-cell expansion in mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 947, doi. 10.1038/leu.2014.275

By:

Deligne, C;
Metidji, A;
Fridman, W-H;
Teillaud, J-L

Publication type:

Article

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 994, doi. 10.1038/leu.2014.329

By:

De Falco, F;
Sabatini, R;
Falzetti, F;
Di Ianni, M;
Sportoletti, P;
Baldoni, S;
Del Papa, B;
Screpanti, I;
Marconi, P;
Rosati, E

Publication type:

Article

Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 877, doi. 10.1038/leu.2014.297

By:

Malcikova, J;
Stano-Kozubik, K;
Tichy, B;
Kantorova, B;
Pavlova, S;
Tom, N;
Radova, L;
Smardova, J;
Pardy, F;
Doubek, M;
Brychtova, Y;
Mraz, M;
Plevova, K;
Diviskova, E;
Oltova, A;
Mayer, J;
Pospisilova, S;
Trbusek, M

Publication type:

Article

Therapy of older persons with acute myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 759, doi. 10.1038/leu.2014.337

By:

Gale, R P;
Hochhaus, A

Publication type:

Article

The role of TLR8 signaling in acute myeloid leukemia differentiation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 918, doi. 10.1038/leu.2014.293

By:

Ignatz-Hoover, J J;
Wang, H;
Moreton, S A;
Chakrabarti, A;
Agarwal, M K;
Sun, K;
Gupta, K;
Wald, D N

Publication type:

Article

IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 939, doi. 10.1038/leu.2014.310

By:

Liu, Y;
Wu, Y;
Wang, Y;
Cai, Y;
Hu, B;
Bao, G;
Fang, H;
Zhao, L;
Ma, S;
Cheng, Q;
Song, Y;
Zhu, Z;
Chang, H;
Yu, X;
Sun, A;
Zhang, Y;
Vignali, D A A;
Wu, D;
Liu, H

Publication type:

Article

A novel view of the adult bone marrow stem cell hierarchy and stem cell trafficking.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 776, doi. 10.1038/leu.2014.346

By:

Ratajczak, M Z

Publication type:

Article

Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 988, doi. 10.1038/leu.2014.327

By:

Bradbury, C;
Houlton, A E;
Akiki, S;
Gregg, R;
Rindl, M;
Khan, J;
Ward, J;
Khan, N;
Griffiths, M;
Nagra, S;
Hills, R;
Burnett, A;
Russell, N;
Vyas, P;
Grimwade, D;
Craddock, C;
Freeman, S D

Publication type:

Article

Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-κB pathway activation but not with poor prognosis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 977, doi. 10.1038/leu.2014.317

By:

Poglio, S;
Cahu, X;
Uzan, B;
Besnard-Guérin, C;
Lapillonne, H;
Leblanc, T;
Baruchel, A;
Landman-Parker, J;
Petit, A;
Baleydier, F;
Amsellem, S;
Baud, V;
Ballerini, P;
Pflumio, F

Publication type:

Article

Epigenetic aging upon allogeneic transplantation: the hematopoietic niche does not affect age-associated DNA methylation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 985, doi. 10.1038/leu.2014.323

By:

Weidner, C I;
Ziegler, P;
Hahn, M;
Brümmendorf, T H;
Ho, A D;
Dreger, P;
Wagner, W

Publication type:

Article

Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 927, doi. 10.1038/leu.2014.292

By:

Shields, B J;
Alserihi, R;
Nasa, C;
Bogue, C;
Alexander, W S;
McCormack, M P

Publication type:

Article

A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 968, doi. 10.1038/leu.2014.302

By:

Ortega, M;
Bhatnagar, H;
Lin, A-P;
Wang, L;
Aster, J C;
Sill, H;
Aguiar, R C T

Publication type:

Article

Clonal origins of ETV6-RUNX1<sup>+</sup> acute lymphoblastic leukemia: studies in monozygotic twins.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 839, doi. 10.1038/leu.2014.322

By:

Alpar, D;
Wren, D;
Ermini, L;
Mansur, M B;
van Delft, F W;
Bateman, C M;
Titley, I;
Kearney, L;
Szczepanski, T;
Gonzalez, D;
Ford, A M;
Potter, N E;
Greaves, M

Publication type:

Article

SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 847, doi. 10.1038/leu.2014.301

By:

Inoue, D;
Kitaura, J;
Matsui, H;
Hou, H-A;
Chou, W-C;
Nagamachi, A;
Kawabata, K C;
Togami, K;
Nagase, R;
Horikawa, S;
Saika, M;
Micol, J-B;
Hayashi, Y;
Harada, Y;
Harada, H;
Inaba, T;
Tien, H-F;
Abdel-Wahab, O;
Kitamura, T

Publication type:

Article

The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 958, doi. 10.1038/leu.2014.291

By:

Ferretti, E;
Tripodo, C;
Pagnan, G;
Guarnotta, C;
Marimpietri, D;
Corrias, M V;
Ribatti, D;
Zupo, S;
Fraternali-Orcioni, G;
Ravetti, J L;
Pistoia, V;
Corcione, A

Publication type:

Article

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 909, doi. 10.1038/leu.2014.303

By:

Okeyo-Owuor, T;
White, B S;
Chatrikhi, R;
Mohan, D R;
Kim, S;
Griffith, M;
Ding, L;
Ketkar-Kulkarni, S;
Hundal, J;
Laird, K M;
Kielkopf, C L;
Ley, T J;
Walter, M J;
Graubert, T A

Publication type:

Article

The rate of transformation from JAK2-mutated ET to PV is influenced by an accurate WHO-defined clinico-morphological diagnosis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 992, doi. 10.1038/leu.2014.328

By:

Barbui, T;
Thiele, J;
Carobbio, A;
Vannucchi, A M;
Tefferi, A

Publication type:

Article

Functional characterization of BTK<sup>C481S</sup> mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 895, doi. 10.1038/leu.2014.263

By:

Cheng, S;
Guo, A;
Lu, P;
Ma, J;
Coleman, M;
Wang, Y L

Publication type:

Article

Grb10 is involved in BCR-ABL-positive leukemia in mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 858, doi. 10.1038/leu.2014.283

By:

Illert, A L;
Albers, C;
Kreutmair, S;
Leischner, H;
Peschel, C;
Miething, C;
Duyster, J

Publication type:

Article

Management of older or unfit patients with acute myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 4, p. 770, doi. 10.1038/leu.2014.216

By:

Walter, R B;
Estey, E H

Publication type:

Article