Works matching IS 08876924 AND DT 2015 AND VI 29 AND IP 2

Results: 44

Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.

Published in:

2015

By:

Suzuki, R;
Hideshima, T;
Mimura, N;
Minami, J;
Ohguchi, H;
Kikuchi, S;
Yoshida, Y;
Gorgun, G;
Cirstea, D;
Cottini, F;
Jakubikova, J;
Tai, Y-T;
Chauhan, D;
Richardson, P G;
Munshi, N C;
Utsugi, T;
Anderson, K C

Publication type:

Letter

The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.

Published in:

2015

By:

Piva, R;
Deaglio, S;
Famà, R;
Buonincontri, R;
Scarfò, I;
Bruscaggin, A;
Mereu, E;
Serra, S;
Spina, V;
Brusa, D;
Garaffo, G;
Monti, S;
Dal Bo, M;
Marasca, R;
Arcaini, L;
Neri, A;
Gattei, V;
Paulli, M;
Tiacci, E;
Bertoni, F

Publication type:

Letter

Genomic and epigenomic co-evolution in follicular lymphomas.

Published in:

2015

By:

Loeffler, M;
Kreuz, M;
Haake, A;
Hasenclever, D;
Trautmann, H;
Arnold, C;
Winter, K;
Koch, K;
Klapper, W;
Scholtysik, R;
Rosolowski, M;
Hoffmann, S;
Ammerpohl, O;
Szczepanowski, M;
Herrmann, D;
Küppers, R;
Pott, C;
Siebert, R;
HaematoSys-Project

Publication type:

journal article

Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).

Published in:

2015

By:

Coppin, E;
Gelsi-Boyer, V;
Morelli, X;
Cervera, N;
Murati, A;
Pandolfi, P P;
Birnbaum, D;
Nunès, J A

Publication type:

Letter

PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.

Published in:

2015

By:

Hartsink-Segers, S A;
Beaudoin, J J;
Luijendijk, M W J;
Exalto, C;
Pieters, R;
Den Boer, M L

Publication type:

journal article

Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.

Published in:

2015

By:

Wesolowska-Andersen, A;
Borst, L;
Dalgaard, M D;
Yadav, R;
Rasmussen, K K;
Wehner, P S;
Rasmussen, M;
ørntoft, T F;
Nordentoft, I;
Koehler, R;
Bartram, C R;
Schrappe, M;
Sicheritz-Ponten, T;
Gautier, L;
Marquart, H;
Madsen, H O;
Brunak, S;
Stanulla, M;
Gupta, R;
Schmiegelow, K

Publication type:

journal article

CSNK1α1 mediates malignant plasma cell survival.

Published in:

2015

By:

Hu, Y;
Song, W;
Cirstea, D;
Lu, D;
Munshi, N C;
Anderson, K C

Publication type:

journal article

Basal Ca(2+) signaling is particularly increased in mutated chronic lymphocytic leukemia.

Published in:

2015

By:

Muggen, A F;
Pillai, S Y;
Kil, L P;
van Zelm, M C;
van Dongen, J J M;
Hendriks, R W;
Langerak, A W

Publication type:

journal article

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

Published in:

2015

By:

Wichmann, C;
Quagliano-Lo Coco, I;
Yildiz, Ö;
Chen-Wichmann, L;
Weber, H;
Syzonenko, T;
Döring, C;
Brendel, C;
Ponnusamy, K;
Kinner, A;
Brandts, C;
Henschler, R;
Grez, M

Publication type:

journal article

The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 503, doi. 10.1038/leu.2014.294

By:

Piva, R;
Deaglio, S;
Famà, R;
Buonincontri, R;
Scarfò, I;
Bruscaggin, A;
Mereu, E;
Serra, S;
Spina, V;
Brusa, D;
Garaffo, G;
Monti, S;
Dal Bo, M;
Marasca, R;
Arcaini, L;
Neri, A;
Gattei, V;
Paulli, M;
Tiacci, E;
Bertoni, F

Publication type:

Article

A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 423, doi. 10.1038/leu.2014.221

By:

Conway, A E;
Haldeman, J M;
Wechsler, D S;
Lavau, C P

Publication type:

Article

Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 297, doi. 10.1038/leu.2014.205

By:

Wesołowska-Andersen, A;
Borst, L;
Dalgaard, M D;
Yadav, R;
Rasmussen, K K;
Wehner, P S;
Rasmussen, M;
Ørntoft, T F;
Nordentoft, I;
Koehler, R;
Bartram, C R;
Schrappe, M;
Sicheritz-Ponten, T;
Gautier, L;
Marquart, H;
Madsen, H O;
Brunak, S;
Stanulla, M;
Gupta, R;
Schmiegelow, K

Publication type:

Article

Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 329, doi. 10.1038/leu.2014.196

By:

Baliakas, P;
Hadzidimitriou, A;
Sutton, L-A;
Rossi, D;
Minga, E;
Villamor, N;
Larrayoz, M;
Kminkova, J;
Agathangelidis, A;
Davis, Z;
Tausch, E;
Stalika, E;
Kantorova, B;
Mansouri, L;
Scarfò, L;
Cortese, D;
Navrkalova, V;
Rose-Zerilli, M J J;
Smedby, K E;
Juliusson, G

Publication type:

Article

Basal Ca<sup>2+</sup> signaling is particularly increased in mutated chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 321, doi. 10.1038/leu.2014.188

By:

Muggen, A F;
Pillai, S Y;
Kil, L P;
van Zelm, M C;
van Dongen, J J M;
Hendriks, R W;
Langerak, A W

Publication type:

Article

IgM peak independently predicts treatment-free survival in chronic lymphocytic leukemia and correlates with accumulation of adverse oncogenetic events.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 337, doi. 10.1038/leu.2014.198

By:

Rizzo, D;
Chauzeix, J;
Trimoreau, F;
Woillard, J B;
Genevieve, F;
Bouvier, A;
Labrousse, J;
Poli, C;
Guerin, E;
Dmytruk, N;
Remenieras, L;
Feuillard, J;
Gachard, N

Publication type:

Article

IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 415, doi. 10.1038/leu.2014.215

By:

Pegram, H J;
Purdon, T J;
van Leeuwen, D G;
Curran, K J;
Giralt, S A;
Barker, J N;
Brentjens, R J

Publication type:

Article

PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 304, doi. 10.1038/leu.2014.210

By:

Hartsink-Segers, S A;
Beaudoin, J J;
Luijendijk, M W J;
Exalto, C;
Pieters, R;
Den Boer, M L

Publication type:

Article

Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 387, doi. 10.1038/leu.2014.174

By:

Chan, W K;
Suwannasaen, D;
Throm, R E;
Li, Y;
Eldridge, P W;
Houston, J;
Gray, J T;
Pui, C-H;
Leung, W

Publication type:

Article

DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 516, doi. 10.1038/leu.2014.269

By:

Im, A P;
Sehgal, A R;
Carroll, M P;
Smith, B D;
Tefferi, A;
Johnson, D E;
Boyiadzis, M

Publication type:

Article

Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 269, doi. 10.1038/leu.2014.257

By:

Sportoletti, P;
Varasano, E;
Rossi, R;
Mupo, A;
Tiacci, E;
Vassiliou, G;
Martelli, M P;
Falini, B

Publication type:

Article

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 356, doi. 10.1038/leu.2014.207

By:

Vaisitti, T;
Audrito, V;
Serra, S;
Buonincontri, R;
Sociali, G;
Mannino, E;
Pagnani, A;
Zucchetto, A;
Tissino, E;
Vitale, C;
Coscia, M;
Usai, C;
Pepper, C;
Gattei, V;
Bruzzone, S;
Deaglio, S

Publication type:

Article

Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 515, doi. 10.1038/leu.2014.265

By:

Yang, J;
He, J;
Wang, J;
Cao, Y;
Ling, J;
Qian, J;
Lu, Y;
Li, H;
Zheng, Y;
Lan, Y;
Hong, S;
Matthews, J;
Starbuck, M W;
Navone, N M;
Orlowski, R Z;
Lin, P;
Kwak, L W;
Yi, Q

Publication type:

Article

Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 406, doi. 10.1038/leu.2014.185

By:

Macor, P;
Secco, E;
Mezzaroba, N;
Zorzet, S;
Durigutto, P;
Gaiotto, T;
De Maso, L;
Biffi, S;
Garrovo, C;
Capolla, S;
Tripodo, C;
Gattei, V;
Marzari, R;
Tedesco, F;
Sblattero, D

Publication type:

Article

Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 290, doi. 10.1038/leu.2014.172

By:

Koh, K;
Tomizawa, D;
Moriya Saito, A;
Watanabe, T;
Miyamura, T;
Hirayama, M;
Takahashi, Y;
Ogawa, A;
Kato, K;
Sugita, K;
Sato, T;
Deguchi, T;
Hayashi, Y;
Takita, J;
Takeshita, Y;
Tsurusawa, M;
Horibe, K;
Mizutani, S;
Ishii, E

Publication type:

Article

Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 312, doi. 10.1038/leu.2014.242

By:

Walter, R B;
Othus, M;
Burnett, A K;
Löwenberg, B;
Kantarjian, H M;
Ossenkoppele, G J;
Hills, R K;
Ravandi, F;
Pabst, T;
Evans, A;
Pierce, S R;
Vekemans, M-C;
Appelbaum, F R;
Estey, E H

Publication type:

Article

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 279, doi. 10.1038/leu.2014.179

By:

Wichmann, C;
Quagliano-Lo Coco, I;
Yildiz, Ö;
Chen-Wichmann, L;
Weber, H;
Syzonenko, T;
Döring, C;
Brendel, C;
Ponnusamy, K;
Kinner, A;
Brandts, C;
Henschler, R;
Grez, M

Publication type:

Article

Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 500, doi. 10.1038/leu.2014.288

By:

Coppin, E;
Gelsi-Boyer, V;
Morelli, X;
Cervera, N;
Murati, A;
Pandolfi, P P;
Birnbaum, D;
Nunès, J A

Publication type:

Article

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 396, doi. 10.1038/leu.2014.180

By:

Peccatori, J;
Forcina, A;
Clerici, D;
Crocchiolo, R;
Vago, L;
Stanghellini, M T L;
Noviello, M;
Messina, C;
Crotta, A;
Assanelli, A;
Marktel, S;
Olek, S;
Mastaglio, S;
Giglio, F;
Crucitti, L;
Lorusso, A;
Guggiari, E;
Lunghi, F;
Carrabba, M;
Tassara, M

Publication type:

Article

MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 494, doi. 10.1038/leu.2014.285

By:

Kollmann, K;
Nangalia, J;
Warsch, W;
Quentmeier, H;
Bench, A;
Boyd, E;
Scott, M;
Drexler, H G;
Green, A R

Publication type:

Article

Diet-induced obesity promotes a myeloma-like condition in vivo.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 507, doi. 10.1038/leu.2014.295

By:

Lwin, S T;
Olechnowicz, S W Z;
Fowler, J A;
Edwards, C M

Publication type:

Article

Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 510, doi. 10.1038/leu.2014.300

By:

Suzuki, R;
Hideshima, T;
Mimura, N;
Minami, J;
Ohguchi, H;
Kikuchi, S;
Yoshida, Y;
Gorgun, G;
Cirstea, D;
Cottini, F;
Jakubikova, J;
Tai, Y-T;
Chauhan, D;
Richardson, P G;
Munshi, N C;
Utsugi, T;
Anderson, K C

Publication type:

Article

Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 433, doi. 10.1038/leu.2014.183

By:

Fukuda, S;
Hoggatt, J;
Singh, P;
Abe, M;
Speth, J M;
Hu, P;
Conway, E M;
Nucifora, G;
Yamaguchi, S;
Pelus, L M

Publication type:

Article

Second cancers and late mortality in Australian children treated by allogeneic HSCT for haematological malignancy.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 441, doi. 10.1038/leu.2014.203

By:

Nelson, A S;
Ashton, L J;
Vajdic, C M;
Le Marsney, R E;
Daniels, B;
Nivison-Smith, I;
Wilcox, L;
Dodds, A J;
O'Brien, T A

Publication type:

Article

Phospho-flow detection of constitutive and cytokine-induced pSTAT3/5, pAKT and pERK expression highlights novel prognostic biomarkers for patients with multiple myeloma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 483, doi. 10.1038/leu.2014.204

By:

Brown, R;
Yang, S;
Weatherburn, C;
Gibson, J;
Ho, P J;
Suen, H;
Hart, D;
Joshua, D

Publication type:

Article

Sequential myeloablative autologous stem cell transplantation and reduced intensity allogeneic hematopoietic cell transplantation is safe and feasible in children, adolescents and young adults with poor-risk refractory or recurrent Hodgkin and non-Hodgkin lymphoma

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 448, doi. 10.1038/leu.2014.194

By:

Satwani, P;
Jin, Z;
Martin, P L;
Bhatia, M;
Garvin, J H;
George, D;
Chaudhury, S;
Talano, J;
Morris, E;
Harrison, L;
Sosna, J;
Peterson, M;
Militano, O;
Foley, S;
Kurtzberg, J;
Cairo, M S

Publication type:

Article

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 346, doi. 10.1038/leu.2014.199

By:

Mani, R;
Mao, Y;
Frissora, F W;
Chiang, C-L;
Wang, J;
Zhao, Y;
Wu, Y;
Yu, B;
Yan, R;
Mo, X;
Yu, L;
Flynn, J;
Jones, J;
Andritsos, L;
Baskar, S;
Rader, C;
Phelps, M A;
Chen, C-S;
Lee, R J;
Byrd, J C

Publication type:

Article

Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 491, doi. 10.1038/leu.2014.284

By:

Fordham, S E;
Cole, M;
Irving, J A;
Allan, J M

Publication type:

Article

A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 369, doi. 10.1038/leu.2014.217

By:

White, H;
Deprez, L;
Corbisier, P;
Hall, V;
Lin, F;
Mazoua, S;
Trapmann, S;
Aggerholm, A;
Andrikovics, H;
Akiki, S;
Barbany, G;
Boeckx, N;
Bench, A;
Catherwood, M;
Cayuela, J-M;
Chudleigh, S;
Clench, T;
Colomer, D;
Daraio, F;
Dulucq, S

Publication type:

Article

The EBMT/EMCL consensus project on the role of autologous and allogeneic stem cell transplantation in mantle cell lymphoma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 464, doi. 10.1038/leu.2014.223

By:

Robinson, S;
Dreger, P;
Caballero, D;
Corradini, P;
Geisler, C;
Ghielmini, M;
Le Gouill, S;
Kimby, E;
Rule, S;
Vitolo, U;
Dreyling, M;
Hermine, O

Publication type:

Article

Early assessment of minimal residual disease in AML by flow cytometry during aplasia identifies patients at increased risk of relapse.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 377, doi. 10.1038/leu.2014.186

By:

Köhnke, T;
Sauter, D;
Ringel, K;
Hoster, E;
Laubender, R P;
Hubmann, M;
Bohlander, S K;
Kakadia, P M;
Schneider, S;
Dufour, A;
Sauerland, M-C;
Berdel, W E;
Büchner, T;
Wörmann, B;
Braess, J;
Hiddemann, W;
Spiekermann, K;
Subklewe, M

Publication type:

Article

CSNK1α1 mediates malignant plasma cell survival.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 474, doi. 10.1038/leu.2014.202

By:

Hu, Y;
Song, W;
Cirstea, D;
Lu, D;
Munshi, N C;
Anderson, K C

Publication type:

Article

Revised assessment of response and long-term discontinuation rates among 111 patients with myelofibrosis treated with momelotinib or ruxolitinib.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 498, doi. 10.1038/leu.2014.286

By:

Abdelrahman, R A;
Begna, K H;
Al-Kali, A;
Hogan, W J;
Litzow, M R;
Tefferi, A

Publication type:

Article

Myelodysplasia is in the niche: novel concepts and emerging therapies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 259, doi. 10.1038/leu.2014.325

By:

Bulycheva, E;
Rauner, M;
Medyouf, H;
Theurl, I;
Bornhäuser, M;
Hofbauer, L C;
Platzbecker, U

Publication type:

Article

Genomic and epigenomic co-evolution in follicular lymphomas.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 456, doi. 10.1038/leu.2014.209

By:

Loeffler, M;
Kreuz, M;
Haake, A;
Hasenclever, D;
Trautmann, H;
Arnold, C;
Winter, K;
Koch, K;
Klapper, W;
Scholtysik, R;
Rosolowski, M;
Hoffmann, S;
Ammerpohl, O;
Szczepanowski, M;
Herrmann, D;
Küppers, R;
Pott, C;
Siebert, R

Publication type:

Article