Search Results | Scholarly Articles, Journals, and E-Books

Select item for more details and to access through your institution.

Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.
Published in:
2015
By:
- Suzuki, R;
- Hideshima, T;
- Mimura, N;
- Minami, J;
- Ohguchi, H;
- Kikuchi, S;
- Yoshida, Y;
- Gorgun, G;
- Cirstea, D;
- Cottini, F;
- Jakubikova, J;
- Tai, Y-T;
- Chauhan, D;
- Richardson, P G;
- Munshi, N C;
- Utsugi, T;
- Anderson, K C
Publication type:
Letter
The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.
Published in:
2015
By:
- Piva, R;
- Deaglio, S;
- Famà, R;
- Buonincontri, R;
- Scarfò, I;
- Bruscaggin, A;
- Mereu, E;
- Serra, S;
- Spina, V;
- Brusa, D;
- Garaffo, G;
- Monti, S;
- Dal Bo, M;
- Marasca, R;
- Arcaini, L;
- Neri, A;
- Gattei, V;
- Paulli, M;
- Tiacci, E;
- Bertoni, F
Publication type:
Letter
Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).
Published in:
2015
By:
- Coppin, E;
- Gelsi-Boyer, V;
- Morelli, X;
- Cervera, N;
- Murati, A;
- Pandolfi, P P;
- Birnbaum, D;
- Nunès, J A
Publication type:
Letter
Genomic and epigenomic co-evolution in follicular lymphomas.
Published in:
2015
By:
- Loeffler, M;
- Kreuz, M;
- Haake, A;
- Hasenclever, D;
- Trautmann, H;
- Arnold, C;
- Winter, K;
- Koch, K;
- Klapper, W;
- Scholtysik, R;
- Rosolowski, M;
- Hoffmann, S;
- Ammerpohl, O;
- Szczepanowski, M;
- Herrmann, D;
- Küppers, R;
- Pott, C;
- Siebert, R;
- HaematoSys-Project
Publication type:
journal article
PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.
Published in:
2015
By:
- Hartsink-Segers, S A;
- Beaudoin, J J;
- Luijendijk, M W J;
- Exalto, C;
- Pieters, R;
- Den Boer, M L
Publication type:
journal article
Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.
Published in:
2015
By:
- Wesolowska-Andersen, A;
- Borst, L;
- Dalgaard, M D;
- Yadav, R;
- Rasmussen, K K;
- Wehner, P S;
- Rasmussen, M;
- ørntoft, T F;
- Nordentoft, I;
- Koehler, R;
- Bartram, C R;
- Schrappe, M;
- Sicheritz-Ponten, T;
- Gautier, L;
- Marquart, H;
- Madsen, H O;
- Brunak, S;
- Stanulla, M;
- Gupta, R;
- Schmiegelow, K
Publication type:
journal article
CSNK1α1 mediates malignant plasma cell survival.
Published in:
2015
By:
- Hu, Y;
- Song, W;
- Cirstea, D;
- Lu, D;
- Munshi, N C;
- Anderson, K C
Publication type:
journal article
The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 503, doi. 10.1038/leu.2014.294
By:
- Piva, R;
- Deaglio, S;
- Famà, R;
- Buonincontri, R;
- Scarfò, I;
- Bruscaggin, A;
- Mereu, E;
- Serra, S;
- Spina, V;
- Brusa, D;
- Garaffo, G;
- Monti, S;
- Dal Bo, M;
- Marasca, R;
- Arcaini, L;
- Neri, A;
- Gattei, V;
- Paulli, M;
- Tiacci, E;
- Bertoni, F
Publication type:
Article
Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.
Published in:
2015
By:
- Wichmann, C;
- Quagliano-Lo Coco, I;
- Yildiz, Ö;
- Chen-Wichmann, L;
- Weber, H;
- Syzonenko, T;
- Döring, C;
- Brendel, C;
- Ponnusamy, K;
- Kinner, A;
- Brandts, C;
- Henschler, R;
- Grez, M
Publication type:
journal article
Basal Ca(2+) signaling is particularly increased in mutated chronic lymphocytic leukemia.
Published in:
2015
By:
- Muggen, A F;
- Pillai, S Y;
- Kil, L P;
- van Zelm, M C;
- van Dongen, J J M;
- Hendriks, R W;
- Langerak, A W
Publication type:
journal article
A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 423, doi. 10.1038/leu.2014.221
By:
- Conway, A E;
- Haldeman, J M;
- Wechsler, D S;
- Lavau, C P
Publication type:
Article
Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 297, doi. 10.1038/leu.2014.205
By:
- Wesołowska-Andersen, A;
- Borst, L;
- Dalgaard, M D;
- Yadav, R;
- Rasmussen, K K;
- Wehner, P S;
- Rasmussen, M;
- Ørntoft, T F;
- Nordentoft, I;
- Koehler, R;
- Bartram, C R;
- Schrappe, M;
- Sicheritz-Ponten, T;
- Gautier, L;
- Marquart, H;
- Madsen, H O;
- Brunak, S;
- Stanulla, M;
- Gupta, R;
- Schmiegelow, K
Publication type:
Article
Recurrent mutations refine prognosis in chronic lymphocytic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 329, doi. 10.1038/leu.2014.196
By:
- Baliakas, P;
- Hadzidimitriou, A;
- Sutton, L-A;
- Rossi, D;
- Minga, E;
- Villamor, N;
- Larrayoz, M;
- Kminkova, J;
- Agathangelidis, A;
- Davis, Z;
- Tausch, E;
- Stalika, E;
- Kantorova, B;
- Mansouri, L;
- Scarfò, L;
- Cortese, D;
- Navrkalova, V;
- Rose-Zerilli, M J J;
- Smedby, K E;
- Juliusson, G
Publication type:
Article
Basal Ca<sup>2+</sup> signaling is particularly increased in mutated chronic lymphocytic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 321, doi. 10.1038/leu.2014.188
By:
- Muggen, A F;
- Pillai, S Y;
- Kil, L P;
- van Zelm, M C;
- van Dongen, J J M;
- Hendriks, R W;
- Langerak, A W
Publication type:
Article
IgM peak independently predicts treatment-free survival in chronic lymphocytic leukemia and correlates with accumulation of adverse oncogenetic events.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 337, doi. 10.1038/leu.2014.198
By:
- Rizzo, D;
- Chauzeix, J;
- Trimoreau, F;
- Woillard, J B;
- Genevieve, F;
- Bouvier, A;
- Labrousse, J;
- Poli, C;
- Guerin, E;
- Dmytruk, N;
- Remenieras, L;
- Feuillard, J;
- Gachard, N
Publication type:
Article
IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 415, doi. 10.1038/leu.2014.215
By:
- Pegram, H J;
- Purdon, T J;
- van Leeuwen, D G;
- Curran, K J;
- Giralt, S A;
- Barker, J N;
- Brentjens, R J
Publication type:
Article
PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 304, doi. 10.1038/leu.2014.210
By:
- Hartsink-Segers, S A;
- Beaudoin, J J;
- Luijendijk, M W J;
- Exalto, C;
- Pieters, R;
- Den Boer, M L
Publication type:
Article
Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 387, doi. 10.1038/leu.2014.174
By:
- Chan, W K;
- Suwannasaen, D;
- Throm, R E;
- Li, Y;
- Eldridge, P W;
- Houston, J;
- Gray, J T;
- Pui, C-H;
- Leung, W
Publication type:
Article
DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 516, doi. 10.1038/leu.2014.269
By:
- Im, A P;
- Sehgal, A R;
- Carroll, M P;
- Smith, B D;
- Tefferi, A;
- Johnson, D E;
- Boyiadzis, M
Publication type:
Article
Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 269, doi. 10.1038/leu.2014.257
By:
- Sportoletti, P;
- Varasano, E;
- Rossi, R;
- Mupo, A;
- Tiacci, E;
- Vassiliou, G;
- Martelli, M P;
- Falini, B
Publication type:
Article
The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 356, doi. 10.1038/leu.2014.207
By:
- Vaisitti, T;
- Audrito, V;
- Serra, S;
- Buonincontri, R;
- Sociali, G;
- Mannino, E;
- Pagnani, A;
- Zucchetto, A;
- Tissino, E;
- Vitale, C;
- Coscia, M;
- Usai, C;
- Pepper, C;
- Gattei, V;
- Bruzzone, S;
- Deaglio, S
Publication type:
Article
Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 515, doi. 10.1038/leu.2014.265
By:
- Yang, J;
- He, J;
- Wang, J;
- Cao, Y;
- Ling, J;
- Qian, J;
- Lu, Y;
- Li, H;
- Zheng, Y;
- Lan, Y;
- Hong, S;
- Matthews, J;
- Starbuck, M W;
- Navone, N M;
- Orlowski, R Z;
- Lin, P;
- Kwak, L W;
- Yi, Q
Publication type:
Article
Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 406, doi. 10.1038/leu.2014.185
By:
- Macor, P;
- Secco, E;
- Mezzaroba, N;
- Zorzet, S;
- Durigutto, P;
- Gaiotto, T;
- De Maso, L;
- Biffi, S;
- Garrovo, C;
- Capolla, S;
- Tripodo, C;
- Gattei, V;
- Marzari, R;
- Tedesco, F;
- Sblattero, D
Publication type:
Article
Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 290, doi. 10.1038/leu.2014.172
By:
- Koh, K;
- Tomizawa, D;
- Moriya Saito, A;
- Watanabe, T;
- Miyamura, T;
- Hirayama, M;
- Takahashi, Y;
- Ogawa, A;
- Kato, K;
- Sugita, K;
- Sato, T;
- Deguchi, T;
- Hayashi, Y;
- Takita, J;
- Takeshita, Y;
- Tsurusawa, M;
- Horibe, K;
- Mizutani, S;
- Ishii, E
Publication type:
Article
Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 312, doi. 10.1038/leu.2014.242
By:
- Walter, R B;
- Othus, M;
- Burnett, A K;
- Löwenberg, B;
- Kantarjian, H M;
- Ossenkoppele, G J;
- Hills, R K;
- Ravandi, F;
- Pabst, T;
- Evans, A;
- Pierce, S R;
- Vekemans, M-C;
- Appelbaum, F R;
- Estey, E H
Publication type:
Article
Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 279, doi. 10.1038/leu.2014.179
By:
- Wichmann, C;
- Quagliano-Lo Coco, I;
- Yildiz, Ö;
- Chen-Wichmann, L;
- Weber, H;
- Syzonenko, T;
- Döring, C;
- Brendel, C;
- Ponnusamy, K;
- Kinner, A;
- Brandts, C;
- Henschler, R;
- Grez, M
Publication type:
Article
Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 500, doi. 10.1038/leu.2014.288
By:
- Coppin, E;
- Gelsi-Boyer, V;
- Morelli, X;
- Cervera, N;
- Murati, A;
- Pandolfi, P P;
- Birnbaum, D;
- Nunès, J A
Publication type:
Article
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 396, doi. 10.1038/leu.2014.180
By:
- Peccatori, J;
- Forcina, A;
- Clerici, D;
- Crocchiolo, R;
- Vago, L;
- Stanghellini, M T L;
- Noviello, M;
- Messina, C;
- Crotta, A;
- Assanelli, A;
- Marktel, S;
- Olek, S;
- Mastaglio, S;
- Giglio, F;
- Crucitti, L;
- Lorusso, A;
- Guggiari, E;
- Lunghi, F;
- Carrabba, M;
- Tassara, M
Publication type:
Article
MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 494, doi. 10.1038/leu.2014.285
By:
- Kollmann, K;
- Nangalia, J;
- Warsch, W;
- Quentmeier, H;
- Bench, A;
- Boyd, E;
- Scott, M;
- Drexler, H G;
- Green, A R
Publication type:
Article
Diet-induced obesity promotes a myeloma-like condition in vivo.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 507, doi. 10.1038/leu.2014.295
By:
- Lwin, S T;
- Olechnowicz, S W Z;
- Fowler, J A;
- Edwards, C M
Publication type:
Article
Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 510, doi. 10.1038/leu.2014.300
By:
- Suzuki, R;
- Hideshima, T;
- Mimura, N;
- Minami, J;
- Ohguchi, H;
- Kikuchi, S;
- Yoshida, Y;
- Gorgun, G;
- Cirstea, D;
- Cottini, F;
- Jakubikova, J;
- Tai, Y-T;
- Chauhan, D;
- Richardson, P G;
- Munshi, N C;
- Utsugi, T;
- Anderson, K C
Publication type:
Article
Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 433, doi. 10.1038/leu.2014.183
By:
- Fukuda, S;
- Hoggatt, J;
- Singh, P;
- Abe, M;
- Speth, J M;
- Hu, P;
- Conway, E M;
- Nucifora, G;
- Yamaguchi, S;
- Pelus, L M
Publication type:
Article
Second cancers and late mortality in Australian children treated by allogeneic HSCT for haematological malignancy.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 441, doi. 10.1038/leu.2014.203
By:
- Nelson, A S;
- Ashton, L J;
- Vajdic, C M;
- Le Marsney, R E;
- Daniels, B;
- Nivison-Smith, I;
- Wilcox, L;
- Dodds, A J;
- O'Brien, T A
Publication type:
Article
Phospho-flow detection of constitutive and cytokine-induced pSTAT3/5, pAKT and pERK expression highlights novel prognostic biomarkers for patients with multiple myeloma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 483, doi. 10.1038/leu.2014.204
By:
- Brown, R;
- Yang, S;
- Weatherburn, C;
- Gibson, J;
- Ho, P J;
- Suen, H;
- Hart, D;
- Joshua, D
Publication type:
Article
Sequential myeloablative autologous stem cell transplantation and reduced intensity allogeneic hematopoietic cell transplantation is safe and feasible in children, adolescents and young adults with poor-risk refractory or recurrent Hodgkin and non-Hodgkin lymphoma
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 448, doi. 10.1038/leu.2014.194
By:
- Satwani, P;
- Jin, Z;
- Martin, P L;
- Bhatia, M;
- Garvin, J H;
- George, D;
- Chaudhury, S;
- Talano, J;
- Morris, E;
- Harrison, L;
- Sosna, J;
- Peterson, M;
- Militano, O;
- Foley, S;
- Kurtzberg, J;
- Cairo, M S
Publication type:
Article
Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 346, doi. 10.1038/leu.2014.199
By:
- Mani, R;
- Mao, Y;
- Frissora, F W;
- Chiang, C-L;
- Wang, J;
- Zhao, Y;
- Wu, Y;
- Yu, B;
- Yan, R;
- Mo, X;
- Yu, L;
- Flynn, J;
- Jones, J;
- Andritsos, L;
- Baskar, S;
- Rader, C;
- Phelps, M A;
- Chen, C-S;
- Lee, R J;
- Byrd, J C
Publication type:
Article
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 491, doi. 10.1038/leu.2014.284
By:
- Fordham, S E;
- Cole, M;
- Irving, J A;
- Allan, J M
Publication type:
Article
A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 369, doi. 10.1038/leu.2014.217
By:
- White, H;
- Deprez, L;
- Corbisier, P;
- Hall, V;
- Lin, F;
- Mazoua, S;
- Trapmann, S;
- Aggerholm, A;
- Andrikovics, H;
- Akiki, S;
- Barbany, G;
- Boeckx, N;
- Bench, A;
- Catherwood, M;
- Cayuela, J-M;
- Chudleigh, S;
- Clench, T;
- Colomer, D;
- Daraio, F;
- Dulucq, S
Publication type:
Article
The EBMT/EMCL consensus project on the role of autologous and allogeneic stem cell transplantation in mantle cell lymphoma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 464, doi. 10.1038/leu.2014.223
By:
- Robinson, S;
- Dreger, P;
- Caballero, D;
- Corradini, P;
- Geisler, C;
- Ghielmini, M;
- Le Gouill, S;
- Kimby, E;
- Rule, S;
- Vitolo, U;
- Dreyling, M;
- Hermine, O
Publication type:
Article
Early assessment of minimal residual disease in AML by flow cytometry during aplasia identifies patients at increased risk of relapse.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 377, doi. 10.1038/leu.2014.186
By:
- Köhnke, T;
- Sauter, D;
- Ringel, K;
- Hoster, E;
- Laubender, R P;
- Hubmann, M;
- Bohlander, S K;
- Kakadia, P M;
- Schneider, S;
- Dufour, A;
- Sauerland, M-C;
- Berdel, W E;
- Büchner, T;
- Wörmann, B;
- Braess, J;
- Hiddemann, W;
- Spiekermann, K;
- Subklewe, M
Publication type:
Article
CSNK1α1 mediates malignant plasma cell survival.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 474, doi. 10.1038/leu.2014.202
By:
- Hu, Y;
- Song, W;
- Cirstea, D;
- Lu, D;
- Munshi, N C;
- Anderson, K C
Publication type:
Article
Revised assessment of response and long-term discontinuation rates among 111 patients with myelofibrosis treated with momelotinib or ruxolitinib.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 498, doi. 10.1038/leu.2014.286
By:
- Abdelrahman, R A;
- Begna, K H;
- Al-Kali, A;
- Hogan, W J;
- Litzow, M R;
- Tefferi, A
Publication type:
Article
Myelodysplasia is in the niche: novel concepts and emerging therapies.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 259, doi. 10.1038/leu.2014.325
By:
- Bulycheva, E;
- Rauner, M;
- Medyouf, H;
- Theurl, I;
- Bornhäuser, M;
- Hofbauer, L C;
- Platzbecker, U
Publication type:
Article
Genomic and epigenomic co-evolution in follicular lymphomas.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 456, doi. 10.1038/leu.2014.209
By:
- Loeffler, M;
- Kreuz, M;
- Haake, A;
- Hasenclever, D;
- Trautmann, H;
- Arnold, C;
- Winter, K;
- Koch, K;
- Klapper, W;
- Scholtysik, R;
- Rosolowski, M;
- Hoffmann, S;
- Ammerpohl, O;
- Szczepanowski, M;
- Herrmann, D;
- Küppers, R;
- Pott, C;
- Siebert, R
Publication type:
Article

Found: 44