Works matching IS 08876924 AND DT 2015 AND VI 29 AND IP 1

Results: 41

A multiepitope of XBP1, CD138 and CS1 peptides induces myeloma-specific cytotoxic T lymphocytes in T cells of smoldering myeloma patients.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 218, doi. 10.1038/leu.2014.159

By:

Bae, J;
Prabhala, R;
Voskertchian, A;
Brown, A;
Maguire, C;
Richardson, P;
Dranoff, G;
Anderson, K C;
Munshi, N C

Publication type:

Article

Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia.

Published in:

2015

By:

Schafranek, L;
Nievergall, E;
Powell, J A;
Hiwase, D K;
Leclercq, T;
Hughes, T P;
White, D L

Publication type:

journal article

Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 157, doi. 10.1038/leu.2014.162

By:

Sharma, A;
Yun, H;
Jyotsana, N;
Chaturvedi, A;
Schwarzer, A;
Yung, E;
Lai, C K;
Kuchenbauer, F;
Argiropoulos, B;
Görlich, K;
Ganser, A;
Humphries, R K;
Heuser, M

Publication type:

Article

In vitro induction of antibody secretion of primary B-cell chronic lymphocytic leukaemia cells.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 244, doi. 10.1038/leu.2014.266

By:

Hoogeboom, R;
Reinten, R J A;
Schot, J-J;
Guikema, J E J;
Bende, R J;
van Noesel, C J M

Publication type:

Article

Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.

Published in:

2015

By:

Sharma, A;
Yun, H;
Jyotsana, N;
Chaturvedi, A;
Schwarzer, A;
Yung, E;
Lai, C K;
Kuchenbauer, F;
Argiropoulos, B;
Görlich, K;
Ganser, A;
Humphries, R K;
Heuser, M

Publication type:

journal article

Evolutionary trajectories of hyperdiploid ALL in monozygotic twins.

Published in:

2015

By:

Bateman, C M;
Alpar, D;
Ford, A M;
Colman, S M;
Wren, D;
Morgan, M;
Kearney, L;
Greaves, M

Publication type:

journal article

The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia.

Published in:

2015

By:

Cao, Y;
Hunter, Z R;
Liu, X;
Xu, L;
Yang, G;
Chen, J;
Patterson, C J;
Tsakmaklis, N;
Kanan, S;
Rodig, S;
Castillo, J J;
Treon, S P

Publication type:

journal article

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation.

Published in:

2015

By:

Palacios, F;
Abreu, C;
Prieto, D;
Morande, P;
Ruiz, S;
Fernández-Calero, T;
Naya, H;
Libisch, G;
Robello, C;
Landoni, A I;
Gabus, R;
Dighiero, G;
Oppezzo, P

Publication type:

journal article

Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.

Published in:

2015

By:

Theocharides, A P A;
Dobson, S M;
Laurenti, E;
Notta, F;
Voisin, V;
Cheng, P-Y;
Yuan, J S;
Guidos, C J;
Minden, M D;
Mullighan, C G;
Torlakovic, E;
Dick, J E

Publication type:

journal article

The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells.

Published in:

2015

By:

López-Guerra, M;
Xargay-Torrent, S;
Rosich, L;
Montraveta, A;
Roldán, J;
Matas-Céspedes, A;
Villamor, N;
Aymerich, M;
López-Otín, C;
Pérez-Galán, P;
Roué, G;
Campo, E;
Colomer, D

Publication type:

journal article

Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 27, doi. 10.1038/leu.2014.149

By:

Weisberg, E;
Nonami, A;
Chen, Z;
Liu, F;
Zhang, J;
Sattler, M;
Nelson, E;
Cowens, K;
Christie, A L;
Mitsiades, C;
Wong, K-K;
Liu, Q;
Gray, N;
Griffin, J D

Publication type:

Article

Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma.

Published in:

2015

By:

Hiasa, M;
Teramachi, J;
Oda, A;
Amachi, R;
Harada, T;
Nakamura, S;
Miki, H;
Fujii, S;
Kagawa, K;
Watanabe, K;
Endo, I;
Kuroda, Y;
Yoneda, T;
Tsuji, D;
Nakao, M;
Tanaka, E;
Hamada, K;
Sano, S;
Itoh, K;
Matsumoto, T

Publication type:

journal article

Prediction of non-relapse mortality in recipients of reduced intensity conditioning allogeneic stem cell transplantation with AML in first complete remission.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 51, doi. 10.1038/leu.2014.164

By:

Versluis, J;
Labopin, M;
Niederwieser, D;
Socie, G;
Schlenk, R F;
Milpied, N;
Nagler, A;
Blaise, D;
Rocha, V;
Cornelissen, J J;
Mohty, M

Publication type:

Article

Evolutionary trajectories of hyperdiploid ALL in monozygotic twins.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 58, doi. 10.1038/leu.2014.177

By:

Bateman, C M;
Alpar, D;
Ford, A M;
Colman, S M;
Wren, D;
Morgan, M;
Kearney, L;
Greaves, M

Publication type:

Article

Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 177, doi. 10.1038/leu.2014.150

By:

Theocharides, A P A;
Dobson, S M;
Laurenti, E;
Notta, F;
Voisin, V;
Cheng, P-Y;
Yuan, J S;
Guidos, C J;
Minden, M D;
Mullighan, C G;
Torlakovic, E;
Dick, J E

Publication type:

Article

Clinical end points for drug treatment trials in BCR-ABL1-negative classic myeloproliferative neoplasms: consensus statements from European LeukemiaNET (ELN) and Internation Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT).

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 20, doi. 10.1038/leu.2014.250

By:

Barosi, G;
Tefferi, A;
Besses, C;
Birgegard, G;
Cervantes, F;
Finazzi, G;
Gisslinger, H;
Griesshammer, M;
Harrison, C;
Hehlmann, R;
Hermouet, S;
Kiladjian, J-J;
Kröger, N;
Mesa, R;
Mc Mullin, M F;
Pardanani, A;
Passamonti, F;
Samuelsson, J;
Vannucchi, A M;
Reiter, A

Publication type:

Article

Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 207, doi. 10.1038/leu.2014.147

By:

Hiasa, M;
Teramachi, J;
Oda, A;
Amachi, R;
Harada, T;
Nakamura, S;
Miki, H;
Fujii, S;
Kagawa, K;
Watanabe, K;
Endo, I;
Kuroda, Y;
Yoneda, T;
Tsuji, D;
Nakao, M;
Tanaka, E;
Hamada, K;
Sano, S;
Itoh, K;
Matsumoto, T

Publication type:

Article

Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 249, doi. 10.1038/leu.2014.270

By:

Cabagnols, X;
Defour, J P;
Ugo, V;
Ianotto, J C;
Mossuz, P;
Mondet, J;
Girodon, F;
Alexandre, J H;
Mansier, O;
Viallard, J F;
Lippert, E;
Murati, A;
Mozziconacci, M J;
Saussoy, P;
Vekemans, M C;
Knoops, L;
Pasquier, F;
Ribrag, V;
Solary, E;
Plo, I

Publication type:

Article

Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 76, doi. 10.1038/leu.2014.156

By:

Schafranek, L;
Nievergall, E;
Powell, J A;
Hiwase, D K;
Leclercq, T;
Hughes, T P;
White, D L

Publication type:

Article

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 38, doi. 10.1038/leu.2014.154

By:

Bardini, M;
Woll, P S;
Corral, L;
Luc, S;
Wittmann, L;
Ma, Z;
Lo Nigro, L;
Basso, G;
Biondi, A;
Cazzaniga, G;
Jacobsen, S E W

Publication type:

Article

Value of routine 'day 14' marrow exam in newly diagnosed AML.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 247, doi. 10.1038/leu.2014.268

By:

Yezefski, T;
Xie, H;
Walter, R;
Pagel, J;
Becker, P S;
Hendrie, P;
Sandhu, V;
Shannon-Dorcy, K;
Abkowitz, J;
Appelbaum, F R;
Estey, E

Publication type:

Article

SRSF2 and U2AF1 mutations in primary myelofibrosis are associated with JAK2 and MPL but not calreticulin mutation and may independently reoccur after allogeneic stem cell transplantation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 253, doi. 10.1038/leu.2014.277

By:

Bartels, S;
Lehmann, U;
Büsche, G;
Schlue, J;
Mozer, M;
Stadler, J;
Triviai, I;
Alchalby, H;
Kröger, N;
Kreipe, H

Publication type:

Article

The tumor microenvironment is the main source of IL-6 for plasma cell tumor development in mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 233, doi. 10.1038/leu.2014.260

By:

Rosean, T R;
Tompkins, V S;
Olivier, A K;
Sompallae, R;
Norian, L A;
Morse, H C;
Waldschmidt, T J;
Janz, S

Publication type:

Article

Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 230, doi. 10.1038/leu.2014.256

By:

Yeung, D T;
Moulton, D J;
Heatley, S L;
Nievergall, E;
Dang, P;
Braley, J;
Branford, S;
Moore, S;
Mullighan, C G;
Hughes, T P;
White, D L

Publication type:

Article

PRPF8 defects cause missplicing in myeloid malignancies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 126, doi. 10.1038/leu.2014.144

By:

Kurtovic-Kozaric, A;
Przychodzen, B;
Singh, J;
Konarska, M M;
Clemente, M J;
Otrock, Z K;
Nakashima, M;
Hsi, E D;
Yoshida, K;
Shiraishi, Y;
Chiba, K;
Tanaka, H;
Miyano, S;
Ogawa, S;
Boultwood, J;
Makishima, H;
Maciejewski, J P;
Padgett, R A

Publication type:

Article

Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 107, doi. 10.1038/leu.2014.146

By:

Middleton, O;
Cosimo, E;
Dobbin, E;
McCaig, A M;
Clarke, C;
Brant, A M;
Leach, M T;
Michie, A M;
Wheadon, H

Publication type:

Article

Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 86, doi. 10.1038/leu.2014.139

By:

Veronese, A;
Pepe, F;
Chiacchia, J;
Pagotto, S;
Lanuti, P;
Veschi, S;
Di Marco, M;
D'Argenio, A;
Innocenti, I;
Vannata, B;
Autore, F;
Marchisio, M;
Wernicke, D;
Verginelli, F;
Leone, G;
Rassenti, L Z;
Kipps, T J;
Mariani-Costantini, R;
Laurenti, L;
Croce, C M

Publication type:

Article

The importance of central pathology review in international trials: a comparison of local versus central bone marrow reticulin grading.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 241, doi. 10.1038/leu.2014.262

By:

Pozdnyakova, O;
Rodig, S;
Bhandarkar, S;
Wu, K;
Thiele, J;
Hasserjian, R

Publication type:

Article

Targeted mutational profiling of peripheral T-cell lymphoma not otherwise specified highlights new mechanisms in a heterogeneous pathogenesis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 237, doi. 10.1038/leu.2014.261

By:

Schatz, J H;
Horwitz, S M;
Teruya-Feldstein, J;
Lunning, M A;
Viale, A;
Huberman, K;
Socci, N D;
Lailler, N;
Heguy, A;
Dolgalev, I;
Migliacci, J C;
Pirun, M;
Palomba, M L;
Weinstock, D M;
Wendel, H-G

Publication type:

Article

Comparison of minimal residual disease as outcome predictor for AML patients in first complete remission undergoing myeloablative or nonmyeloablative allogeneic hematopoietic cell transplantation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 137, doi. 10.1038/leu.2014.173

By:

Walter, R B;
Gyurkocza, B;
Storer, B E;
Godwin, C D;
Pagel, J M;
Buckley, S A;
Sorror, M L;
Wood, B L;
Storb, R;
Appelbaum, F R;
Sandmaier, B M

Publication type:

Article

Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 145, doi. 10.1038/leu.2014.151

By:

Sato, A;
Nishida, C;
Sato-Kusubata, K;
Ishihara, M;
Tashiro, Y;
Gritli, I;
Shimazu, H;
Munakata, S;
Yagita, H;
Okumura, K;
Tsuda, Y;
Okada, Y;
Tojo, A;
Nakauchi, H;
Takahashi, S;
Heissig, B;
Hattori, K

Publication type:

Article

Transient abnormal myelopoiesis/acute megakaryoblastic leukemia diagnosed in the placenta of a stillborn Down syndrome fetus with targeted next-generation sequencing.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 232, doi. 10.1038/leu.2014.258

By:

Federmann, B;
Fasan, A;
Kagan, K O;
Haen, S;
Fend, F

Publication type:

Article

Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 66, doi. 10.1038/leu.2014.161

By:

Della Porta, M G;
Travaglino, E;
Boveri, E;
Ponzoni, M;
Malcovati, L;
Papaemmanuil, E;
Rigolin, G M;
Pascutto, C;
Croci, G;
Gianelli, U;
Milani, R;
Ambaglio, I;
Elena, C;
Ubezio, M;
Da Via', M C;
Bono, E;
Pietra, D;
Quaglia, F;
Bastia, R;
Ferretti, V

Publication type:

Article

Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 188, doi. 10.1038/leu.2014.170

By:

Visconte, V;
Avishai, N;
Mahfouz, R;
Tabarroki, A;
Cowen, J;
Sharghi-Moshtaghin, R;
Hitomi, M;
Rogers, H J;
Hasrouni, E;
Phillips, J;
Sekeres, M A;
Heuer, A H;
Saunthararajah, Y;
Barnard, J;
Tiu, R V

Publication type:

Article

piRNA-823 contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 196, doi. 10.1038/leu.2014.135

By:

Yan, H;
Wu, Q-L;
Sun, C-Y;
Ai, L-S;
Deng, J;
Zhang, L;
Chen, L;
Chu, Z-B;
Tang, B;
Wang, K;
Wu, X-F;
Xu, J;
Hu, Y

Publication type:

Article

Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 255, doi. 10.1038/leu.2014.278

By:

Kraus, M;
Dolinski, B;
Rosahl, T W;
Magee, J A

Publication type:

Article

Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 11, doi. 10.1038/leu.2014.222

By:

Gjertsen, B T;
Schöffski, P

Publication type:

Article

Cell-based strategies to manage leukemia relapse: efficacy and feasibility of immunotherapy approaches.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 1, doi. 10.1038/leu.2014.189

By:

Rambaldi, A;
Biagi, E;
Bonini, C;
Biondi, A;
Introna, M

Publication type:

Article

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 115, doi. 10.1038/leu.2014.158

By:

Palacios, F;
Abreu, C;
Prieto, D;
Morande, P;
Ruiz, S;
Fernández-Calero, T;
Naya, H;
Libisch, G;
Robello, C;
Landoni, A I;
Gabus, R;
Dighiero, G;
Oppezzo, P

Publication type:

Article

The WHIM-like CXCR4<sup>S338X</sup> somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 169, doi. 10.1038/leu.2014.187

By:

Cao, Y;
Hunter, Z R;
Liu, X;
Xu, L;
Yang, G;
Chen, J;
Patterson, C J;
Tsakmaklis, N;
Kanan, S;
Rodig, S;
Castillo, J J;
Treon, S P

Publication type:

Article

The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 96, doi. 10.1038/leu.2014.143

By:

López-Guerra, M;
Xargay-Torrent, S;
Rosich, L;
Montraveta, A;
Roldán, J;
Matas-Céspedes, A;
Villamor, N;
Aymerich, M;
López-Otín, C;
Pérez-Galán, P;
Roué, G;
Campo, E;
Colomer, D

Publication type:

Article