Works matching IS 08876924 AND DT 2014 AND VI 28 AND IP 3

Results: 43

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 577, doi. 10.1038/leu.2013.264

By:

Stankov, M V;
El Khatib, M;
Kumar Thakur, B;
Heitmann, K;
Panayotova-Dimitrova, D;
Schoening, J;
Bourquin, J P;
Schweitzer, N;
Leverkus, M;
Welte, K;
Reinhardt, D;
Li, Z;
Orkin, S H;
Behrens, G M N;
Klusmann, J H

Publication type:

Article

Rapid rate of peripheral blood blast clearance accurately predicts complete remission in acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 713, doi. 10.1038/leu.2013.341

By:

Vainstein, V;
Buckley, S A;
Shukron, O;
Estey, E H;
Abkowitz, J L;
Wood, B L;
Walter, R B

Publication type:

Article

Inherited genetic susceptibility to multiple myeloma.

Published in:

2014

By:

Morgan, G J;
Johnson, D C;
Weinhold, N;
Goldschmidt, H;
Landgren, O;
Lynch, H T;
Hemminki, K;
Houlston, R S

Publication type:

journal article

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.

Published in:

2014

By:

Solary, E;
Bernard, O A;
Tefferi, A;
Fuks, F;
Vainchenker, W

Publication type:

journal article

CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 609, doi. 10.1038/leu.2013.354

By:

Slamova, L;
Starkova, J;
Fronkova, E;
Zaliova, M;
Reznickova, L;
van Delft, F W;
Vodickova, E;
Volejnikova, J;
Zemanova, Z;
Polgarova, K;
Cario, G;
Figueroa, M;
Kalina, T;
Fiser, K;
Bourquin, J P;
Bornhauser, B;
Dworzak, M;
Zuna, J;
Trka, J;
Stary, J

Publication type:

Article

Differential expression of miR-17~92 identifies BCL2 as a therapeutic target in BCR-ABL-positive B-lineage acute lymphoblastic leukemia.

Published in:

2014

By:

Scherr, M;
Elder, A;
Battmer, K;
Barzan, D;
Bomken, S;
Ricke-Hoch, M;
Schröder, A;
Venturini, L;
Blair, H J;
Vormoor, J;
Ottmann, O;
Ganser, A;
Pich, A;
Hilfiker-Kleiner, D;
Heidenreich, O;
Eder, M

Publication type:

journal article

Epigenetics of myelodysplastic syndromes.

Published in:

2014

By:

Itzykson, R;
Fenaux, P

Publication type:

journal article

CD49d expression identifies a chronic-lymphocytic leukemia subset with high levels of mobilized circulating CD34(+) hemopoietic progenitors cells.

Published in:

2014

By:

Rossi, F M;
Zucchetto, A;
Tissino, E;
Dal Bo, M;
Bomben, R;
Caldana, C;
Pozzo, F;
Del Poeta, G;
Rossi, D;
Gaidano, G;
Gattei, V

Publication type:

Letter

CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.

Published in:

2014

By:

Brault, L;
Rovó, A;
Decker, S;
Dierks, C;
Tzankov, A;
Schwaller, J

Publication type:

journal article

Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 589, doi. 10.1038/leu.2013.342

By:

Kampen, K R;
ter Elst, A;
Mahmud, H;
Scherpen, F J G;
Diks, S H;
Peppelenbosch, M P;
de Haas, V;
Guryev, V;
de Bont, E S J M

Publication type:

Article

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.

Published in:

2014

By:

Valencia, A;
Masala, E;
Rossi, A;
Martino, A;
Sanna, A;
Buchi, F;
Canzian, F;
Cilloni, D;
Gaidano, V;
Voso, M T;
Kosmider, O;
Fontenay, M;
Gozzini, A;
Bosi, A;
Santini, V

Publication type:

journal article

KRas(G12D)-evoked leukemogenesis does not require β-catenin.

Published in:

2014

By:

Ng, C E L;
Sinha, A;
Krivtsov, A;
Dias, S;
Chang, J;
Armstrong, S A;
Kalaitzidis, D

Publication type:

Letter

Elevated PTPN2 expression is associated with inferior molecular response in de-novo chronic myeloid leukaemia patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 702, doi. 10.1038/leu.2013.329

By:

Kok, C H;
Leclercq, T;
Watkins, D B;
Saunders, V;
Wang, J;
Hughes, T P;
White, D L

Publication type:

Article

Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: recent pros and cons in the midst of a lively debate.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 473, doi. 10.1038/leu.2013.255

By:

Ratajczak, M Z;
Zuba-Surma, E;
Wojakowski, W;
Suszynska, M;
Mierzejewska, K;
Liu, R;
Ratajczak, J;
Shin, D M;
Kucia, M

Publication type:

Article

Global phosphoproteome analysis of human bone marrow reveals predictive phosphorylation markers for the treatment of acute myeloid leukemia with quizartinib.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 716, doi. 10.1038/leu.2013.347

By:

Schaab, C;
Oppermann, F S;
Klammer, M;
Pfeifer, H;
Tebbe, A;
Oellerich, T;
Krauter, J;
Levis, M;
Perl, A E;
Daub, H;
Steffen, B;
Godl, K;
Serve, H

Publication type:

Article

PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 629, doi. 10.1038/leu.2013.351

By:

Berger, A;
Hoelbl-Kovacic, A;
Bourgeais, J;
Hoefling, L;
Warsch, W;
Grundschober, E;
Uras, I Z;
Menzl, I;
Putz, E M;
Hoermann, G;
Schuster, C;
Fajmann, S;
Leitner, E;
Kubicek, S;
Moriggl, R;
Gouilleux, F;
Sexl, V

Publication type:

Article

Ph+ ALL patients in first complete remission have similar survival after reduced intensity and myeloablative allogeneic transplantation: impact of tyrosine kinase inhibitor and minimal residual disease.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 658, doi. 10.1038/leu.2013.253

By:

Bachanova, V;
Marks, D I;
Zhang, M-J;
Wang, H;
de Lima, M;
Aljurf, M D;
Arellano, M;
Artz, A S;
Bacher, U;
Cahn, J-Y;
Chen, Y-B;
Copelan, E A;
Drobyski, W R;
Gale, R P;
Greer, J P;
Gupta, V;
Hale, G A;
Kebriaei, P;
Lazarus, H M;
Lewis, I D

Publication type:

Article

Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 680, doi. 10.1038/leu.2013.231

By:

Minami, J;
Suzuki, R;
Mazitschek, R;
Gorgun, G;
Ghosh, B;
Cirstea, D;
Hu, Y;
Mimura, N;
Ohguchi, H;
Cottini, F;
Jakubikova, J;
Munshi, N C;
Haggarty, S J;
Richardson, P G;
Hideshima, T;
Anderson, K C

Publication type:

Article

Cyclin D1 splice site variant triggers chromosomal aberrations in healthy humans.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 721, doi. 10.1038/leu.2013.353

By:

Hemminki, K;
Musak, L;
Vymetalkova, V;
Smerhovsky, Z;
Halasova, E;
Osina, O;
Letkova, L;
Försti, A;
Vodickova, L;
Buchancova, J;
Vodicka, P

Publication type:

Article

Inherited genetic susceptibility to multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 518, doi. 10.1038/leu.2013.344

By:

Morgan, G J;
Johnson, D C;
Weinhold, N;
Goldschmidt, H;
Landgren, O;
Lynch, H T;
Hemminki, K;
Houlston, R S

Publication type:

Article

Ligand-independent FLT3 activation does not cooperate with MLL-AF4 to immortalize/transform cord blood CD34+ cells.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 666, doi. 10.1038/leu.2013.346

By:

Montes, R;
Ayllón, V;
Prieto, C;
Bursen, A;
Prelle, C;
Romero-Moya, D;
Real, P J;
Navarro-Montero, O;
Chillón, C;
Marschalek, R;
Bueno, C;
Menendez, P

Publication type:

Article

Rituximab maintenance therapy after autologous stem cell transplantation prolongs progression-free survival in patients with mantle cell lymphoma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 708, doi. 10.1038/leu.2013.332

By:

Dietrich, S;
Weidle, J;
Rieger, M;
Meissner, J;
Radujkovic, A;
Ho, A D;
Dreger, P;
Witzens-Harig, M

Publication type:

Article

BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 649, doi. 10.1038/leu.2013.358

By:

Cheng, S;
Ma, J;
Guo, A;
Lu, P;
Leonard, J P;
Coleman, M;
Liu, M;
Buggy, J J;
Furman, R R;
Wang, Y L

Publication type:

Article

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 621, doi. 10.1038/leu.2013.330

By:

Valencia, A;
Masala, E;
Rossi, A;
Martino, A;
Sanna, A;
Buchi, F;
Canzian, F;
Cilloni, D;
Gaidano, V;
Voso, M T;
Kosmider, O;
Fontenay, M;
Gozzini, A;
Bosi, A;
Santini, V

Publication type:

Article

New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG).

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 525, doi. 10.1038/leu.2013.350

By:

Ocio, E M;
Richardson, P G;
Rajkumar, S V;
Palumbo, A;
Mateos, M V;
Orlowski, R;
Kumar, S;
Usmani, S;
Roodman, D;
Niesvizky, R;
Einsele, H;
Anderson, K C;
Dimopoulos, M A;
Avet-Loiseau, H;
Mellqvist, U-H;
Turesson, I;
Merlini, G;
Schots, R;
McCarthy, P;
Bergsagel, L

Publication type:

Article

Differential expression of miR-17∼92 identifies BCL2 as a therapeutic target in BCR-ABL-positive B-lineage acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 554, doi. 10.1038/leu.2013.361

By:

Scherr, M;
Elder, A;
Battmer, K;
Barzan, D;
Bomken, S;
Ricke-Hoch, M;
Schröder, A;
Venturini, L;
Blair, H J;
Vormoor, J;
Ottmann, O;
Ganser, A;
Pich, A;
Hilfiker-Kleiner, D;
Heidenreich, O;
Eder, M

Publication type:

Article

High prevalence of oncogenic MYD88 and CD79B mutations in primary testicular diffuse large B-cell lymphoma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 719, doi. 10.1038/leu.2013.348

By:

Kraan, W;
van Keimpema, M;
Horlings, H M;
Schilder-Tol, E J M;
Oud, M E C M;
Noorduyn, L A;
Kluin, P M;
Kersten, M J;
Spaargaren, M;
Pals, S T

Publication type:

Article

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 485, doi. 10.1038/leu.2013.337

By:

Solary, E;
Bernard, O A;
Tefferi, A;
Fuks, F;
Vainchenker, W

Publication type:

Article

Deletion of the 1p32 region is a major independent prognostic factor in young patients with myeloma: the IFM experience on 1195 patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 726, doi. 10.1038/leu.2013.352

By:

Hebraud, B;
Leleu, X;
Lauwers-Cances, V;
Roussel, M;
Caillot, D;
Marit, G;
Karlin, L;
Hulin, C;
Gentil, C;
Guilhot, F;
Garderet, L;
Lamy, T;
Brechignac, S;
Pegourie, B;
Jaubert, J;
Dib, M;
Stoppa, A-M;
Sebban, C;
Fohrer, C;
Fontan, J

Publication type:

Article

Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 694, doi. 10.1038/leu.2013.322

By:

Mansouri, L;
Sutton, L-A;
Ljungström, V;
Sörqvist, E F;
Gunnarsson, R;
Smedby, K E;
Juliusson, G;
Stamatopoulos, K;
Nilsson, M;
Rosenquist, R

Publication type:

Article

CD49d expression identifies a chronic-lymphocytic leukemia subset with high levels of mobilized circulating CD34<sup>+</sup> hemopoietic progenitors cells.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 705, doi. 10.1038/leu.2013.331

By:

Rossi, F M;
Zucchetto, A;
Tissino, E;
Dal Bo, M;
Bomben, R;
Caldana, C;
Pozzo, F;
Del Poeta, G;
Rossi, D;
Gaidano, G;
Gattei, V

Publication type:

Article

CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 566, doi. 10.1038/leu.2013.201

By:

Brault, L;
Rovó, A;
Decker, S;
Dierks, C;
Tzankov, A;
Schwaller, J

Publication type:

Article

On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 710, doi. 10.1038/leu.2013.333

By:

Cortese, D;
Sutton, L-A;
Cahill, N;
Smedby, K E;
Geisler, C;
Gunnarsson, R;
Juliusson, G;
Mansouri, L;
Rosenquist, R

Publication type:

Article

Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 600, doi. 10.1038/leu.2013.345

By:

Kaindl, U;
Morak, M;
Portsmouth, C;
Mecklenbräuker, A;
Kauer, M;
Zeginigg, M;
Attarbaschi, A;
Haas, O A;
Panzer-Grümayer, R

Publication type:

Article

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 543, doi. 10.1038/leu.2013.349

By:

Buontempo, F;
Orsini, E;
Martins, L R;
Antunes, I;
Lonetti, A;
Chiarini, F;
Tabellini, G;
Evangelisti, C;
Melchionda, F;
Pession, A;
Bertaina, A;
Locatelli, F;
McCubrey, J A;
Cappellini, A;
Barata, J T;
Martelli, A M

Publication type:

Article

Deletion of the 1p32 region is a major independent prognostic factor in young patients with myeloma: the IFM experience on 1195 patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 675, doi. 10.1038/leu.2013.225

By:

Hebraud, B;
Leleu, X;
Lauwers-Cances, V;
Roussel, M;
Caillot, D;
Marit, G;
Karlin, L;
Hulin, C;
Gentil, C;
Guilhot, F;
Garderet, L;
Lamy, T;
Brechignac, S;
Pegourie, B;
Jaubert, J;
Dib, M;
Stoppa, A-M;
Sebban, C;
Fohrer, C;
Fontan, J

Publication type:

Article

Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 507, doi. 10.1038/leu.2013.311

By:

Kharfan-Dabaja, M A;
Wierda, W G;
Cooper, L J N

Publication type:

Article

Epigenetics of myelodysplastic syndromes.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 497, doi. 10.1038/leu.2013.343

By:

Itzykson, R;
Fenaux, P

Publication type:

Article

Phase 2 study of oral panobinostat (LBH589) with or without erythropoietin in heavily transfusion-dependent IPSS low or int-1 MDS patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 696, doi. 10.1038/leu.2013.325

By:

Platzbecker, U;
Al-Ali, H K;
Gattermann, N;
Haase, D;
Janzen, V;
Krauter, J;
Götze, K;
Schlenk, R;
Nolte, F;
Letsch, A;
Ottmann, O G;
Kündgen, A;
Lübbert, M;
Germing, U;
Wermke, M;
Reinhard, H;
Weiss, C;
Lieder, K;
Ehninger, G;
Leismann, O

Publication type:

Article

Bendamustine in combination with Ofatumumab in relapsed or refractory chronic lymphocytic leukemia: a GIMEMA Multicenter Phase II Trial.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 642, doi. 10.1038/leu.2013.334

By:

Cortelezzi, A;
Sciumè, M;
Liberati, A M;
Vincenti, D;
Cuneo, A;
Reda, G;
Laurenti, L;
Zaja, F;
Marasca, R;
Chiarenza, A;
Gritti, G;
Orsucci, L;
Storti, S;
Angelucci, E;
Cascavilla, N;
Gobbi, M;
Mauro, F R;
Morabito, F;
Fabris, S;
Piciocchi, A

Publication type:

Article

Consolidation and maintenance therapy with lenalidomide, bortezomib and dexamethasone (RVD) in high-risk myeloma patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 690, doi. 10.1038/leu.2013.335

By:

Nooka, A K;
Kaufman, J L;
Muppidi, S;
Langston, A;
Heffner, L T;
Gleason, C;
Casbourne, D;
Saxe, D;
Boise, L H;
Lonial, S

Publication type:

Article

Impact of the revised International Prognostic Scoring System on the outcome of patients with acute myeloid leukemia with or without antecedent myelodysplastic syndrome.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 723, doi. 10.1038/leu.2013.356

By:

Stölzel, F;
Kramer, M;
Mohr, B;
Wermke, M;
Bornhäuser, M;
Ehninger, G;
Schaich, M;
Platzbecker, U

Publication type:

Article

KRas<sup>G12D</sup>-evoked leukemogenesis does not require β-catenin.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 698, doi. 10.1038/leu.2013.328

By:

Ng, C E L;
Sinha, A;
Krivtsov, A;
Dias, S;
Chang, J;
Armstrong, S A;
Kalaitzidis, D

Publication type:

Article