Works matching IS 08876924 AND DT 2014 AND VI 28 AND IP 2

Results: 44

Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.
Published in:
2014
By:
- Hasan, S;
- Cassinat, B;
- Droin, N;
- Le Couedic, J P;
- Favale, F;
- Monte-Mor, B;
- Lacout, C;
- Fontenay, M;
- Dosquet, C;
- Chomienne, C;
- Solary, E;
- Villeval, J L;
- Casadevall, N;
- Kiladjian, J J;
- Vainchenker, W;
- Plo, I
Publication type:
Letter
IMWG consensus on risk stratification in multiple myeloma.
Published in:
2014
By:
- Chng, W J;
- Dispenzieri, A;
- Chim, C-S;
- Fonseca, R;
- Goldschmidt, H;
- Lentzsch, S;
- Munshi, N;
- Palumbo, A;
- Miguel, J S;
- Sonneveld, P;
- Cavo, M;
- Usmani, S;
- Durie, B Gm;
- Avet-Loiseau, H;
- Durie, B G M;
- International Myeloma Working Group
Publication type:
journal article
No chromosome arm unturned: in memory of Roland Berger 1934-2012.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 464, doi. 10.1038/leu.2013.340
By:
- Harrison, C J;
- Rowley, J D;
- Van den Berghe, H;
- Bernheim, A;
- Martineau, M;
- Gautier, M;
- Le Coniat-Busson, M;
- Romana, S;
- Dastugue, N;
- Hagemeijer, A;
- Jonveaux, P;
- Nguyen-Khac, F;
- Bernard, O A
Publication type:
Article
Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 384, doi. 10.1038/leu.2013.199
By:
- Walker, B A;
- Wardell, C P;
- Melchor, L;
- Brioli, A;
- Johnson, D C;
- Kaiser, M F;
- Mirabella, F;
- Lopez-Corral, L;
- Humphray, S;
- Murray, L;
- Ross, M;
- Bentley, D;
- Gutiérrez, N C;
- Garcia-Sanz, R;
- San Miguel, J;
- Davies, F E;
- Gonzalez, D;
- Morgan, G J
Publication type:
Article
Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 411, doi. 10.1038/leu.2013.265
By:
- Grövdal, M;
- Karimi, M;
- Tobiasson, M;
- Reinius, L;
- Jansson, M;
- Ekwall, K;
- Ungerstedt, J;
- Kere, J;
- Greco, D;
- Hellström-Lindberg, E
Publication type:
Article
Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 278, doi. 10.1038/leu.2013.183
By:
- Agnusdei, V;
- Minuzzo, S;
- Frasson, C;
- Grassi, A;
- Axelrod, F;
- Satyal, S;
- Gurney, A;
- Hoey, T;
- Seganfreddo, E;
- Basso, G;
- Valtorta, S;
- Moresco, R M;
- Amadori, A;
- Indraccolo, S
Publication type:
Article
U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 431, doi. 10.1038/leu.2013.286
By:
- Tefferi, A;
- Finke, C M;
- Lasho, T L;
- Wassie, E A;
- Knudson, R;
- Ketterling, R P;
- Hanson, C A;
- Pardanani, A
Publication type:
Article
JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 338, doi. 10.1038/leu.2013.157
By:
- Bouchekioua, A;
- Scourzic, L;
- de Wever, O;
- Zhang, Y;
- Cervera, P;
- Aline-Fardin, A;
- Mercher, T;
- Gaulard, P;
- Nyga, R;
- Jeziorowska, D;
- Douay, L;
- Vainchenker, W;
- Louache, F;
- Gespach, C;
- Solary, E;
- Coppo, P
Publication type:
Article
Rapid detection of MYD88-L265P mutation by PCR-RFLP in B-cell lymphoproliferative disorders.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 447, doi. 10.1038/leu.2013.294
By:
- Argentou, N;
- Vassilopoulos, G;
- Ioannou, M;
- Germenis, A E;
- Speletas, M
Publication type:
Article
Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 428, doi. 10.1038/leu.2013.280
By:
- De Lorenzo, P;
- Moorman, A V;
- Pieters, R;
- Dreyer, Z E;
- Heerema, N A;
- Carroll, A J;
- Hunger, S P;
- Harvey, R;
- Willman, C L;
- Devidas, M;
- Valsecchi, M-G;
- Harrison, C J
Publication type:
Article
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 311, doi. 10.1038/leu.2013.338
By:
- Dawson, M A;
- Gudgin, E J;
- Horton, S J;
- Giotopoulos, G;
- Meduri, E;
- Robson, S;
- Cannizzaro, E;
- Osaki, H;
- Wiese, M;
- Putwain, S;
- Fong, C Y;
- Grove, C;
- Craig, J;
- Dittmann, A;
- Lugo, D;
- Jeffrey, P;
- Drewes, G;
- Lee, K;
- Bullinger, L;
- Prinjha, R K
Publication type:
Article
The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 451, doi. 10.1038/leu.2013.298
By:
- Boysen, J;
- Sinha, S;
- Price-Troska, T;
- Warner, S L;
- Bearss, D J;
- Viswanatha, D;
- Shanafelt, T D;
- Kay, N E;
- Ghosh, A K
Publication type:
Article
Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 470, doi. 10.1038/leu.2013.276
By:
- Wong, K K;
- Gascoyne, D M;
- Brown, P J;
- Soilleux, E J;
- Snell, C;
- Chen, H;
- Lyne, L;
- Lawrie, C H;
- Gascoyne, R D;
- Pedersen, L M;
- Møller, M B;
- Pulford, K;
- Murphy, D;
- Green, T M;
- Banham, A H
Publication type:
Article
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 241, doi. 10.1038/leu.2013.336
By:
- Haferlach, T;
- Nagata, Y;
- Grossmann, V;
- Okuno, Y;
- Bacher, U;
- Nagae, G;
- Schnittger, S;
- Sanada, M;
- Kon, A;
- Alpermann, T;
- Yoshida, K;
- Roller, A;
- Nadarajah, N;
- Shiraishi, Y;
- Shiozawa, Y;
- Chiba, K;
- Tanaka, H;
- Koeffler, H P;
- Klein, H-U;
- Dugas, M
Publication type:
Article
Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 391, doi. 10.1038/leu.2013.217
By:
- Puig, N;
- Sarasquete, M E;
- Balanzategui, A;
- Martínez, J;
- Paiva, B;
- García, H;
- Fumero, S;
- Jiménez, C;
- Alcoceba, M;
- Chillón, M C;
- Sebastián, E;
- Marín, L;
- Montalbán, M A;
- Mateos, M V;
- Oriol, A;
- Palomera, L;
- de la Rubia, J;
- Vidriales, M B;
- Bladé, J;
- Lahuerta, J J
Publication type:
Article
Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 417, doi. 10.1038/leu.2013.271
By:
- Bellanger, D;
- Jacquemin, V;
- Chopin, M;
- Pierron, G;
- Bernard, O A;
- Ghysdael, J;
- Stern, M-H
Publication type:
Article
Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 302, doi. 10.1038/leu.2013.206
By:
- Olsson, L;
- Castor, A;
- Behrendtz, M;
- Biloglav, A;
- Forestier, E;
- Paulsson, K;
- Johansson, B
Publication type:
Article
Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 407, doi. 10.1038/leu.2013.249
By:
- Axelrod, M;
- Ou, Z;
- Brett, L K;
- Zhang, L;
- Lopez, E R;
- Tamayo, A T;
- Gordon, V;
- Ford, R J;
- Williams, M E;
- Pham, L V;
- Weber, M J;
- Wang, M L
Publication type:
Article
Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 362, doi. 10.1038/leu.2013.224
By:
- Wong, K K;
- Gascoyne, D M;
- Brown, P J;
- Soilleux, E J;
- Snell, C;
- Chen, H;
- Lyne, L;
- Lawrie, C H;
- Gascoyne, R D;
- Pedersen, L M;
- Møller, M B;
- Pulford, K;
- Murphy, D;
- Green, T M;
- Banham, A H
Publication type:
Article
Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 433, doi. 10.1038/leu.2013.287
By:
- Xiang, P;
- Wei, W;
- Lo, C;
- Rosten, P;
- Hou, J;
- Hoodless, P A;
- Bilenky, M;
- Bonifer, C;
- Cockerill, P N;
- Kirkpatrick, A;
- Gottgens, B;
- Hirst, M;
- Humphries, K R
Publication type:
Article
Declining rates of treatment-related mortality in patients with newly diagnosed AML given 'intense' induction regimens: a report from SWOG and MD Anderson.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 289, doi. 10.1038/leu.2013.176
By:
- Othus, M;
- Kantarjian, H;
- Petersdorf, S;
- Ravandi, F;
- Godwin, J;
- Cortes, J;
- Pierce, S;
- Erba, H;
- Faderl, S;
- Appelbaum, F R;
- Estey, E
Publication type:
Article
Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 449, doi. 10.1038/leu.2013.296
By:
- Massa, M;
- Rosti, V;
- Campanelli, R;
- Fois, G;
- Barosi, G
Publication type:
Article
Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 293, doi. 10.1038/leu.2013.168
By:
- Yuan, L L;
- Green, A S;
- Bertoli, S;
- Grimal, F;
- Mansat-De Mas, V;
- Dozier, C;
- Tamburini, J;
- Récher, C;
- Didier, C;
- Manenti, S
Publication type:
Article
Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 426, doi. 10.1038/leu.2013.278
By:
- Yasuda, T;
- Ueno, T;
- Fukumura, K;
- Yamato, A;
- Ando, M;
- Yamaguchi, H;
- Soda, M;
- Kawazu, M;
- Sai, E;
- Yamashita, Y;
- Murata, M;
- Kiyoi, H;
- Naoe, T;
- Mano, H
Publication type:
Article
Relationship between initial clinical presentation and the molecular cytogenetic classification of myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 398, doi. 10.1038/leu.2013.258
By:
- Greenberg, A J;
- Rajkumar, S V;
- Therneau, T M;
- Singh, P P;
- Dispenzieri, A;
- Kumar, S K
Publication type:
Article
Hyperdiploidy with 49-65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 321, doi. 10.1038/leu.2013.198
By:
- Chilton, L;
- Hills, R K;
- Harrison, C J;
- Burnett, A K;
- Grimwade, D;
- Moorman, A V
Publication type:
Article
Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 444, doi. 10.1038/leu.2013.292
By:
- Lemaire, M;
- D'Huyvetter, M;
- Lahoutte, T;
- Van Valckenborgh, E;
- Menu, E;
- De Bruyne, E;
- Kronenberger, P;
- Wernery, U;
- Muyldermans, S;
- Devoogdt, N;
- Vanderkerken, K
Publication type:
Article
The NR4A orphan nuclear receptors do not confer prednisolone resistance in pediatric acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 422, doi. 10.1038/leu.2013.275
By:
- Ariës, I M;
- van den Dungen, E S R;
- Pieters, R;
- den Boer, M L
Publication type:
Article
STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 248, doi. 10.1038/leu.2013.192
By:
- Dorritie, K A;
- McCubrey, J A;
- Johnson, D E
Publication type:
Article
Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348).
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 404, doi. 10.1038/leu.2013.205
By:
- Zhou, T;
- Georgeon, S;
- Moser, R;
- Moore, D J;
- Caflisch, A;
- Hantschel, O
Publication type:
Article
Bone marrow angiogenesis in myeloma and its precursor disease: a prospective clinical trial.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 413, doi. 10.1038/leu.2013.268
By:
- Bhutani, M;
- Turkbey, B;
- Tan, E;
- Kemp, T J;
- Pinto, L A;
- Berg, A R;
- Korde, N;
- Minter, A R;
- Weiss, B M;
- Mena, E;
- Lindenberg, L;
- Aras, O;
- Purdue, M P;
- Hofmann, J N;
- Steinberg, S M;
- Calvo, K R;
- Choyke, P L;
- Maric, I;
- Kurdziel, K;
- Landgren, O
Publication type:
Article
The current status of minimal residual disease assessment in myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 239, doi. 10.1038/leu.2013.306
By:
- Kumar, S K;
- Rajkumar, S V
Publication type:
Article
Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 419, doi. 10.1038/leu.2013.272
By:
- Koschmieder, S;
- Burmeister, T;
- Brüggemann, M;
- Berkemeier, A;
- Volpert, S;
- Wieacker, P;
- Silling, G;
- Gökbuget, N;
- Müller-Tidow, C;
- Berdel, W E;
- Stelljes, M
Publication type:
Article
Long-term results of a randomized phase 3 trial comparing idarubicin and daunorubicin in younger patients with acute myeloid leukaemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 440, doi. 10.1038/leu.2013.290
By:
- Récher, C;
- Béné, M C;
- Lioure, B;
- Pigneux, A;
- Vey, N;
- Delaunay, J;
- Luquet, I;
- Hunault, M;
- Guyotat, D;
- Bouscary, D;
- Fegueux, N;
- Jourdan, E;
- Lissandre, S;
- Escoffre-Barbe, M;
- Bonmati, C;
- Randriamalala, E;
- Guièze, R;
- Ojeda-Uribe, M;
- Dreyfus, F;
- Harousseau, J L
Publication type:
Article
IMWG consensus on risk stratification in multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 269, doi. 10.1038/leu.2013.247
By:
- Chng, W J;
- Dispenzieri, A;
- Chim, C-S;
- Fonseca, R;
- Goldschmidt, H;
- Lentzsch, S;
- Munshi, N;
- Palumbo, A;
- Miguel, J S;
- Sonneveld, P;
- Cavo, M;
- Usmani, S;
- Durie, B GM;
- Avet-Loiseau, H
Publication type:
Article
Long-term response to lenalidomide in patients with newly diagnosed multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 455, doi. 10.1038/leu.2013.300
By:
- Kourelis, T V;
- Kumar, S K;
- Srivastava, G;
- Gertz, M A;
- Lacy, M Q;
- Buadi, F K;
- Kyle, R A;
- Dispenzieri, A
Publication type:
Article
Association of response endpoints with survival outcomes in multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 258, doi. 10.1038/leu.2013.220
By:
- Lonial, S;
- Anderson, K C
Publication type:
Article
Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 373, doi. 10.1038/leu.2013.174
By:
- Bjorklund, C C;
- Baladandayuthapani, V;
- Lin, H Y;
- Jones, R J;
- Kuiatse, I;
- Wang, H;
- Yang, J;
- Shah, J J;
- Thomas, S K;
- Wang, M;
- Weber, D M;
- Orlowski, R Z
Publication type:
Article
A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 436, doi. 10.1038/leu.2013.289
By:
- Sportoletti, P;
- Baldoni, S;
- Del Papa, B;
- Aureli, P;
- Dorillo, E;
- Ruggeri, L;
- Plebani, S;
- Amico, V;
- Di Tommaso, A;
- Rosati, E;
- Marconi, P;
- Di Ianni, M;
- Falzetti, F
Publication type:
Article
Induction of differential apoptotic pathways in multiple myeloma cells by class-selective histone deacetylase inhibitors.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 457, doi. 10.1038/leu.2013.301
By:
- Hideshima, T;
- Mazitschek, R;
- Santo, L;
- Mimura, N;
- Gorgun, G;
- Richardson, P G;
- Raje, N;
- Anderson, K C
Publication type:
Article
Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348).
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 471, doi. 10.1038/leu.2013.299
By:
- Zhou, T;
- Georgeon, S;
- Moser, R;
- Moore, D J;
- Caflisch, A;
- Hantschel, O
Publication type:
Article
Use of the 46/1 haplotype to model JAK2<sup>V617F</sup> clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 460, doi. 10.1038/leu.2013.303
By:
- Hasan, S;
- Cassinat, B;
- Droin, N;
- Le Couedic, J P;
- Favale, F;
- Monte-Mor, B;
- Lacout, C;
- Fontenay, M;
- Dosquet, C;
- Chomienne, C;
- Solary, E;
- Villeval, J L;
- Casadevall, N;
- Kiladjian, J J;
- Vainchenker, W;
- Plo, I
Publication type:
Article
Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 349, doi. 10.1038/leu.2013.158
By:
- Patel, B;
- Kang, Y;
- Cui, K;
- Litt, M;
- Riberio, M S J;
- Deng, C;
- Salz, T;
- Casada, S;
- Fu, X;
- Qiu, Y;
- Zhao, K;
- Huang, S
Publication type:
Article
Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas.
Published in:
Leukemia (08876924), 2014, v. 28, n. 2, p. 329, doi. 10.1038/leu.2013.177
By:
- Sakamaki, I;
- Kwak, L W;
- Cha, S-c;
- Yi, Q;
- Lerman, B;
- Chen, J;
- Surapaneni, S;
- Bateman, S;
- Qin, H
Publication type:
Article