Works matching IS 08876924 AND DT 2014 AND VI 28 AND IP 2

Results: 44

No chromosome arm unturned: in memory of Roland Berger 1934-2012.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 464, doi. 10.1038/leu.2013.340

By:

Harrison, C J;
Rowley, J D;
Van den Berghe, H;
Bernheim, A;
Martineau, M;
Gautier, M;
Le Coniat-Busson, M;
Romana, S;
Dastugue, N;
Hagemeijer, A;
Jonveaux, P;
Nguyen-Khac, F;
Bernard, O A

Publication type:

Article

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 384, doi. 10.1038/leu.2013.199

By:

Walker, B A;
Wardell, C P;
Melchor, L;
Brioli, A;
Johnson, D C;
Kaiser, M F;
Mirabella, F;
Lopez-Corral, L;
Humphray, S;
Murray, L;
Ross, M;
Bentley, D;
Gutiérrez, N C;
Garcia-Sanz, R;
San Miguel, J;
Davies, F E;
Gonzalez, D;
Morgan, G J

Publication type:

Article

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 278, doi. 10.1038/leu.2013.183

By:

Agnusdei, V;
Minuzzo, S;
Frasson, C;
Grassi, A;
Axelrod, F;
Satyal, S;
Gurney, A;
Hoey, T;
Seganfreddo, E;
Basso, G;
Valtorta, S;
Moresco, R M;
Amadori, A;
Indraccolo, S

Publication type:

Article

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 311, doi. 10.1038/leu.2013.338

By:

Dawson, M A;
Gudgin, E J;
Horton, S J;
Giotopoulos, G;
Meduri, E;
Robson, S;
Cannizzaro, E;
Osaki, H;
Wiese, M;
Putwain, S;
Fong, C Y;
Grove, C;
Craig, J;
Dittmann, A;
Lugo, D;
Jeffrey, P;
Drewes, G;
Lee, K;
Bullinger, L;
Prinjha, R K

Publication type:

Article

U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 431, doi. 10.1038/leu.2013.286

By:

Tefferi, A;
Finke, C M;
Lasho, T L;
Wassie, E A;
Knudson, R;
Ketterling, R P;
Hanson, C A;
Pardanani, A

Publication type:

Article

Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.

Published in:

2014

By:

Hasan, S;
Cassinat, B;
Droin, N;
Le Couedic, J P;
Favale, F;
Monte-Mor, B;
Lacout, C;
Fontenay, M;
Dosquet, C;
Chomienne, C;
Solary, E;
Villeval, J L;
Casadevall, N;
Kiladjian, J J;
Vainchenker, W;
Plo, I

Publication type:

Letter

IMWG consensus on risk stratification in multiple myeloma.

Published in:

2014

By:

Chng, W J;
Dispenzieri, A;
Chim, C-S;
Fonseca, R;
Goldschmidt, H;
Lentzsch, S;
Munshi, N;
Palumbo, A;
Miguel, J S;
Sonneveld, P;
Cavo, M;
Usmani, S;
Durie, B Gm;
Avet-Loiseau, H;
Durie, B G M;
International Myeloma Working Group

Publication type:

journal article

JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 338, doi. 10.1038/leu.2013.157

By:

Bouchekioua, A;
Scourzic, L;
de Wever, O;
Zhang, Y;
Cervera, P;
Aline-Fardin, A;
Mercher, T;
Gaulard, P;
Nyga, R;
Jeziorowska, D;
Douay, L;
Vainchenker, W;
Louache, F;
Gespach, C;
Solary, E;
Coppo, P

Publication type:

Article

Rapid detection of MYD88-L265P mutation by PCR-RFLP in B-cell lymphoproliferative disorders.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 447, doi. 10.1038/leu.2013.294

By:

Argentou, N;
Vassilopoulos, G;
Ioannou, M;
Germenis, A E;
Speletas, M

Publication type:

Article

Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 428, doi. 10.1038/leu.2013.280

By:

De Lorenzo, P;
Moorman, A V;
Pieters, R;
Dreyer, Z E;
Heerema, N A;
Carroll, A J;
Hunger, S P;
Harvey, R;
Willman, C L;
Devidas, M;
Valsecchi, M-G;
Harrison, C J

Publication type:

Article

Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 411, doi. 10.1038/leu.2013.265

By:

Grövdal, M;
Karimi, M;
Tobiasson, M;
Reinius, L;
Jansson, M;
Ekwall, K;
Ungerstedt, J;
Kere, J;
Greco, D;
Hellström-Lindberg, E

Publication type:

Article

The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 451, doi. 10.1038/leu.2013.298

By:

Boysen, J;
Sinha, S;
Price-Troska, T;
Warner, S L;
Bearss, D J;
Viswanatha, D;
Shanafelt, T D;
Kay, N E;
Ghosh, A K

Publication type:

Article

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 470, doi. 10.1038/leu.2013.276

By:

Wong, K K;
Gascoyne, D M;
Brown, P J;
Soilleux, E J;
Snell, C;
Chen, H;
Lyne, L;
Lawrie, C H;
Gascoyne, R D;
Pedersen, L M;
Møller, M B;
Pulford, K;
Murphy, D;
Green, T M;
Banham, A H

Publication type:

Article

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 241, doi. 10.1038/leu.2013.336

By:

Haferlach, T;
Nagata, Y;
Grossmann, V;
Okuno, Y;
Bacher, U;
Nagae, G;
Schnittger, S;
Sanada, M;
Kon, A;
Alpermann, T;
Yoshida, K;
Roller, A;
Nadarajah, N;
Shiraishi, Y;
Shiozawa, Y;
Chiba, K;
Tanaka, H;
Koeffler, H P;
Klein, H-U;
Dugas, M

Publication type:

Article

Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 417, doi. 10.1038/leu.2013.271

By:

Bellanger, D;
Jacquemin, V;
Chopin, M;
Pierron, G;
Bernard, O A;
Ghysdael, J;
Stern, M-H

Publication type:

Article

Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 391, doi. 10.1038/leu.2013.217

By:

Puig, N;
Sarasquete, M E;
Balanzategui, A;
Martínez, J;
Paiva, B;
García, H;
Fumero, S;
Jiménez, C;
Alcoceba, M;
Chillón, M C;
Sebastián, E;
Marín, L;
Montalbán, M A;
Mateos, M V;
Oriol, A;
Palomera, L;
de la Rubia, J;
Vidriales, M B;
Bladé, J;
Lahuerta, J J

Publication type:

Article

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 302, doi. 10.1038/leu.2013.206

By:

Olsson, L;
Castor, A;
Behrendtz, M;
Biloglav, A;
Forestier, E;
Paulsson, K;
Johansson, B

Publication type:

Article

Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 407, doi. 10.1038/leu.2013.249

By:

Axelrod, M;
Ou, Z;
Brett, L K;
Zhang, L;
Lopez, E R;
Tamayo, A T;
Gordon, V;
Ford, R J;
Williams, M E;
Pham, L V;
Weber, M J;
Wang, M L

Publication type:

Article

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 362, doi. 10.1038/leu.2013.224

By:

Wong, K K;
Gascoyne, D M;
Brown, P J;
Soilleux, E J;
Snell, C;
Chen, H;
Lyne, L;
Lawrie, C H;
Gascoyne, R D;
Pedersen, L M;
Møller, M B;
Pulford, K;
Murphy, D;
Green, T M;
Banham, A H

Publication type:

Article

Declining rates of treatment-related mortality in patients with newly diagnosed AML given 'intense' induction regimens: a report from SWOG and MD Anderson.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 289, doi. 10.1038/leu.2013.176

By:

Othus, M;
Kantarjian, H;
Petersdorf, S;
Ravandi, F;
Godwin, J;
Cortes, J;
Pierce, S;
Erba, H;
Faderl, S;
Appelbaum, F R;
Estey, E

Publication type:

Article

Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 293, doi. 10.1038/leu.2013.168

By:

Yuan, L L;
Green, A S;
Bertoli, S;
Grimal, F;
Mansat-De Mas, V;
Dozier, C;
Tamburini, J;
Récher, C;
Didier, C;
Manenti, S

Publication type:

Article

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 433, doi. 10.1038/leu.2013.287

By:

Xiang, P;
Wei, W;
Lo, C;
Rosten, P;
Hou, J;
Hoodless, P A;
Bilenky, M;
Bonifer, C;
Cockerill, P N;
Kirkpatrick, A;
Gottgens, B;
Hirst, M;
Humphries, K R

Publication type:

Article

Bone marrow angiogenesis in myeloma and its precursor disease: a prospective clinical trial.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 413, doi. 10.1038/leu.2013.268

By:

Bhutani, M;
Turkbey, B;
Tan, E;
Kemp, T J;
Pinto, L A;
Berg, A R;
Korde, N;
Minter, A R;
Weiss, B M;
Mena, E;
Lindenberg, L;
Aras, O;
Purdue, M P;
Hofmann, J N;
Steinberg, S M;
Calvo, K R;
Choyke, P L;
Maric, I;
Kurdziel, K;
Landgren, O

Publication type:

Article

Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 449, doi. 10.1038/leu.2013.296

By:

Massa, M;
Rosti, V;
Campanelli, R;
Fois, G;
Barosi, G

Publication type:

Article

Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 444, doi. 10.1038/leu.2013.292

By:

Lemaire, M;
D'Huyvetter, M;
Lahoutte, T;
Van Valckenborgh, E;
Menu, E;
De Bruyne, E;
Kronenberger, P;
Wernery, U;
Muyldermans, S;
Devoogdt, N;
Vanderkerken, K

Publication type:

Article

The current status of minimal residual disease assessment in myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 239, doi. 10.1038/leu.2013.306

By:

Kumar, S K;
Rajkumar, S V

Publication type:

Article

Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 426, doi. 10.1038/leu.2013.278

By:

Yasuda, T;
Ueno, T;
Fukumura, K;
Yamato, A;
Ando, M;
Yamaguchi, H;
Soda, M;
Kawazu, M;
Sai, E;
Yamashita, Y;
Murata, M;
Kiyoi, H;
Naoe, T;
Mano, H

Publication type:

Article

STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 248, doi. 10.1038/leu.2013.192

By:

Dorritie, K A;
McCubrey, J A;
Johnson, D E

Publication type:

Article

Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348).

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 404, doi. 10.1038/leu.2013.205

By:

Zhou, T;
Georgeon, S;
Moser, R;
Moore, D J;
Caflisch, A;
Hantschel, O

Publication type:

Article

The NR4A orphan nuclear receptors do not confer prednisolone resistance in pediatric acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 422, doi. 10.1038/leu.2013.275

By:

Ariës, I M;
van den Dungen, E S R;
Pieters, R;
den Boer, M L

Publication type:

Article

Long-term results of a randomized phase 3 trial comparing idarubicin and daunorubicin in younger patients with acute myeloid leukaemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 440, doi. 10.1038/leu.2013.290

By:

Récher, C;
Béné, M C;
Lioure, B;
Pigneux, A;
Vey, N;
Delaunay, J;
Luquet, I;
Hunault, M;
Guyotat, D;
Bouscary, D;
Fegueux, N;
Jourdan, E;
Lissandre, S;
Escoffre-Barbe, M;
Bonmati, C;
Randriamalala, E;
Guièze, R;
Ojeda-Uribe, M;
Dreyfus, F;
Harousseau, J L

Publication type:

Article

Use of the 46/1 haplotype to model JAK2<sup>V617F</sup> clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 460, doi. 10.1038/leu.2013.303

By:

Hasan, S;
Cassinat, B;
Droin, N;
Le Couedic, J P;
Favale, F;
Monte-Mor, B;
Lacout, C;
Fontenay, M;
Dosquet, C;
Chomienne, C;
Solary, E;
Villeval, J L;
Casadevall, N;
Kiladjian, J J;
Vainchenker, W;
Plo, I

Publication type:

Article

Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 373, doi. 10.1038/leu.2013.174

By:

Bjorklund, C C;
Baladandayuthapani, V;
Lin, H Y;
Jones, R J;
Kuiatse, I;
Wang, H;
Yang, J;
Shah, J J;
Thomas, S K;
Wang, M;
Weber, D M;
Orlowski, R Z

Publication type:

Article

Relationship between initial clinical presentation and the molecular cytogenetic classification of myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 398, doi. 10.1038/leu.2013.258

By:

Greenberg, A J;
Rajkumar, S V;
Therneau, T M;
Singh, P P;
Dispenzieri, A;
Kumar, S K

Publication type:

Article

Hyperdiploidy with 49-65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 321, doi. 10.1038/leu.2013.198

By:

Chilton, L;
Hills, R K;
Harrison, C J;
Burnett, A K;
Grimwade, D;
Moorman, A V

Publication type:

Article

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 419, doi. 10.1038/leu.2013.272

By:

Koschmieder, S;
Burmeister, T;
Brüggemann, M;
Berkemeier, A;
Volpert, S;
Wieacker, P;
Silling, G;
Gökbuget, N;
Müller-Tidow, C;
Berdel, W E;
Stelljes, M

Publication type:

Article

IMWG consensus on risk stratification in multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 269, doi. 10.1038/leu.2013.247

By:

Chng, W J;
Dispenzieri, A;
Chim, C-S;
Fonseca, R;
Goldschmidt, H;
Lentzsch, S;
Munshi, N;
Palumbo, A;
Miguel, J S;
Sonneveld, P;
Cavo, M;
Usmani, S;
Durie, B GM;
Avet-Loiseau, H

Publication type:

Article

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 436, doi. 10.1038/leu.2013.289

By:

Sportoletti, P;
Baldoni, S;
Del Papa, B;
Aureli, P;
Dorillo, E;
Ruggeri, L;
Plebani, S;
Amico, V;
Di Tommaso, A;
Rosati, E;
Marconi, P;
Di Ianni, M;
Falzetti, F

Publication type:

Article

Induction of differential apoptotic pathways in multiple myeloma cells by class-selective histone deacetylase inhibitors.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 457, doi. 10.1038/leu.2013.301

By:

Hideshima, T;
Mazitschek, R;
Santo, L;
Mimura, N;
Gorgun, G;
Richardson, P G;
Raje, N;
Anderson, K C

Publication type:

Article

Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348).

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 471, doi. 10.1038/leu.2013.299

By:

Zhou, T;
Georgeon, S;
Moser, R;
Moore, D J;
Caflisch, A;
Hantschel, O

Publication type:

Article

Long-term response to lenalidomide in patients with newly diagnosed multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 455, doi. 10.1038/leu.2013.300

By:

Kourelis, T V;
Kumar, S K;
Srivastava, G;
Gertz, M A;
Lacy, M Q;
Buadi, F K;
Kyle, R A;
Dispenzieri, A

Publication type:

Article

Association of response endpoints with survival outcomes in multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 258, doi. 10.1038/leu.2013.220

By:

Lonial, S;
Anderson, K C

Publication type:

Article

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 349, doi. 10.1038/leu.2013.158

By:

Patel, B;
Kang, Y;
Cui, K;
Litt, M;
Riberio, M S J;
Deng, C;
Salz, T;
Casada, S;
Fu, X;
Qiu, Y;
Zhao, K;
Huang, S

Publication type:

Article

Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 329, doi. 10.1038/leu.2013.177

By:

Sakamaki, I;
Kwak, L W;
Cha, S-c;
Yi, Q;
Lerman, B;
Chen, J;
Surapaneni, S;
Bateman, S;
Qin, H

Publication type:

Article