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Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling.
Published in:
2014
By:
- Spirin, P V;
- Lebedev, T D;
- Orlova, N N;
- Gornostaeva, A S;
- Prokofjeva, M M;
- Nikitenko, N A;
- Dmitriev, S E;
- Buzdin, A A;
- Borisov, N M;
- Aliper, A M;
- Garazha, A V;
- Rubtsov, P M;
- Stocking, C;
- Prassolov, V S
Publication type:
journal article
ASXL1 and SETBP1 mutations and their prognostic contribution in chronic myelomonocytic leukemia: a two-center study of 466 patients.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2206, doi. 10.1038/leu.2014.125
By:
- Patnaik, M M;
- Itzykson, R;
- Lasho, T L;
- Kosmider, O;
- Finke, C M;
- Hanson, C A;
- Knudson, R A;
- Ketterling, R P;
- Tefferi, A;
- Solary, E
Publication type:
Article
Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs).
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2148, doi. 10.1038/leu.2014.115
By:
- Borkowska, S;
- Suszynska, M;
- Mierzejewska, K;
- Ismail, A;
- Budkowska, M;
- Salata, D;
- Dolegowska, B;
- Kucia, M;
- Ratajczak, J;
- Ratajczak, M Z
Publication type:
Article
Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2197, doi. 10.1038/leu.2014.123
By:
- Bertacchini, J;
- Guida, M;
- Accordi, B;
- Mediani, L;
- Martelli, A M;
- Barozzi, P;
- Petricoin, E;
- Liotta, L;
- Milani, G;
- Giordan, M;
- Luppi, M;
- Forghieri, F;
- De Pol, A;
- Cocco, L;
- Basso, G;
- Marmiroli, S
Publication type:
Article
Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas.
Published in:
2014
By:
- Nicolae, A;
- Xi, L;
- Pittaluga, S;
- Abdullaev, Z;
- Pack, S D;
- Chen, J;
- Waldmann, T A;
- Jaffe, E S;
- Raffeld, M
Publication type:
Letter
Mitochondrial priming of chronic lymphocytic leukemia patients associates Bcl-xL dependence with alvocidib response.
Published in:
2014
By:
- Pierceall, W E;
- Warner, S L;
- Lena, R J;
- Doykan, C;
- Blake, N;
- Elashoff, M;
- Hoff, D V;
- Bearss, D J;
- Cardone, M H;
- Andritsos, L;
- Byrd, J C;
- Lanasa, M C;
- Grever, M R;
- Johnson, A J
Publication type:
Letter
Excellent outcome of young adults with aggressive non-Hodgkin lymphomas treated with CHOP-like regimens.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2260, doi. 10.1038/leu.2014.213
By:
- Hohloch, K;
- Zeynalova, S;
- Held, G;
- Ziepert, M;
- Loeffler, M;
- Wulf, G;
- Schmitz, N;
- Pfreundschuh, M;
- Trümper, L
Publication type:
Article
Immunoglobulin light-chain amyloidosis shares genetic susceptibility with multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2254, doi. 10.1038/leu.2014.208
By:
- Weinhold, N;
- Försti, A;
- da Silva Filho, M I;
- Nickel, J;
- Campo, C;
- Hoffmann, P;
- Nöthen, M M;
- Hose, D;
- Goldschmidt, H;
- Jauch, A;
- Langer, C;
- Hegenbart, U;
- Schönland, S O;
- Hemminki, K
Publication type:
Article
Overexpression of CDKN2B (p15INK4B) and altered global DNA methylation status in mesenchymal stem cells of high-risk myelodysplastic syndromes.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2241, doi. 10.1038/leu.2014.197
By:
- Poloni, A;
- Maurizi, G;
- Mattiucci, D;
- Amatori, S;
- Fogliardi, B;
- Costantini, B;
- Mariani, M;
- Mancini, S;
- Olivieri, A;
- Fanelli, M;
- Leoni, P
Publication type:
Article
Heparanase enhances myeloma progression via CXCL10 downregulation.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2178, doi. 10.1038/leu.2014.121
By:
- Barash, U;
- Zohar, Y;
- Wildbaum, G;
- Beider, K;
- Nagler, A;
- Karin, N;
- Ilan, N;
- Vlodavsky, I
Publication type:
Article
Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2213, doi. 10.1038/leu.2014.128
By:
- Busfield, S J;
- Biondo, M;
- Wong, M;
- Ramshaw, H S;
- Lee, E M;
- Ghosh, S;
- Braley, H;
- Panousis, C;
- Roberts, A W;
- He, S Z;
- Thomas, D;
- Fabri, L;
- Vairo, G;
- Lock, R B;
- Lopez, A F;
- Nash, A D
Publication type:
Article
Novel myelofibrosis treatment strategies: potential partners for combination therapies.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2139, doi. 10.1038/leu.2014.176
By:
- Stein, B L;
- Swords, R;
- Hochhaus, A;
- Giles, F
Publication type:
Article
The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2248, doi. 10.1038/leu.2014.201
By:
- Liu, Y;
- Abdul Razak, F R;
- Terpstra, M;
- Chan, F C;
- Saber, A;
- Nijland, M;
- van Imhoff, G;
- Visser, L;
- Gascoyne, R;
- Steidl, C;
- Kluiver, J;
- Diepstra, A;
- Kok, K;
- van den Berg, A
Publication type:
Article
Does ruxolitinib improve survival of persons with MPN-associated myelofibrosis? Should it?
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2267, doi. 10.1038/leu.2014.220
By:
- Barosi, G;
- Zhang, M-J;
- Peter Gale, R
Publication type:
Article
Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2165, doi. 10.1038/leu.2014.120
By:
- Chorzalska, A;
- Salloum, I;
- Shafqat, H;
- Khan, S;
- Marjon, P;
- Treaba, D;
- Schorl, C;
- Morgan, J;
- Bryke, C R;
- Falanga, V;
- Zhao, T C;
- Reagan, J;
- Winer, E;
- Olszewski, A J;
- Al-Homsi, A S;
- Kouttab, N;
- Dubielecka, P M
Publication type:
Article
Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2155, doi. 10.1038/leu.2014.119
By:
- Fiskus, W;
- Sharma, S;
- Shah, B;
- Portier, B P;
- Devaraj, S G T;
- Liu, K;
- Iyer, S P;
- Bearss, D;
- Bhalla, K N
Publication type:
Article
High-throughput drug screening identifies compounds and molecular strategies for targeting proteasome inhibitor-resistant multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2263, doi. 10.1038/leu.2014.214
By:
- Stessman, H A F;
- Lulla, A;
- Xia, T;
- Mitra, A;
- Harding, T;
- Mansoor, A;
- Myers, C L;
- Van Ness, B G;
- Dolloff, N G
Publication type:
Article
How to manage mantle cell lymphoma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2117, doi. 10.1038/leu.2014.171
By:
- Dreyling, M;
- Ferrero, S;
- Hermine, O
Publication type:
Article
Cytokines secreted by bone marrow stromal cells protect c-KIT mutant AML cells from c-KIT inhibitor-induced apoptosis.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2257, doi. 10.1038/leu.2014.212
By:
- Gordon, P M;
- Dias, Stuart;
- Williams, D A
Publication type:
Article
Sensitivity of hematological malignancies to graft-versus-host effects: an EBMT megafile analysis.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2235, doi. 10.1038/leu.2014.145
By:
- Stern, M;
- de Wreede, L C;
- Brand, R;
- van Biezen, A;
- Dreger, P;
- Mohty, M;
- de Witte, T M;
- Kröger, N;
- Ruutu, T
Publication type:
Article
Mitochondrial priming of chronic lymphocytic leukemia patients associates Bcl-x<sub>L</sub> dependence with alvocidib response.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2251, doi. 10.1038/leu.2014.206
By:
- Pierceall, W E;
- Warner, S L;
- Lena, R J;
- Doykan, C;
- Blake, N;
- Elashoff, M;
- Hoff, D V;
- Bearss, D J;
- Cardone, M H;
- Andritsos, L;
- Byrd, J C;
- Lanasa, M C;
- Grever, M R;
- Johnson, A J
Publication type:
Article
Synergy of Myc, cell cycle regulators and the Akt pathway in the development of aggressive B-cell lymphoma in a mouse model.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2270, doi. 10.1038/leu.2014.224
By:
- Arita, K;
- Tsuzuki, S;
- Ohshima, K;
- Sugiyama, T;
- Seto, M
Publication type:
Article
Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2188, doi. 10.1038/leu.2014.122
By:
- Herman, S E M;
- Niemann, C U;
- Farooqui, M;
- Jones, J;
- Mustafa, R Z;
- Lipsky, A;
- Saba, N;
- Martyr, S;
- Soto, S;
- Valdez, J;
- Gyamfi, J A;
- Maric, I;
- Calvo, K R;
- Pedersen, L B;
- Geisler, C H;
- Liu, D;
- Marti, G E;
- Aue, G;
- Wiestner, A
Publication type:
Article
Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2244, doi. 10.1038/leu.2014.200
By:
- Nicolae, A;
- Xi, L;
- Pittaluga, S;
- Abdullaev, Z;
- Pack, S D;
- Chen, J;
- Waldmann, T A;
- Jaffe, E S;
- Raffeld, M
Publication type:
Article
The emerging roles of DOT1L in leukemia and normal development.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2131, doi. 10.1038/leu.2014.169
By:
- McLean, C M;
- Karemaker, I D;
- van Leeuwen, F
Publication type:
Article
Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2222, doi. 10.1038/leu.2014.130
By:
- Spirin, P V;
- Lebedev, T D;
- Orlova, N N;
- Gornostaeva, A S;
- Prokofjeva, M M;
- Nikitenko, N A;
- Dmitriev, S E;
- Buzdin, A A;
- Borisov, N M;
- Aliper, A M;
- Garazha, A V;
- Rubtsov, P M;
- Stocking, C;
- Prassolov, V S
Publication type:
Article
Gene expression profile alone is inadequate in predicting complete response in multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2229, doi. 10.1038/leu.2014.140
By:
- Amin, S B;
- Yip, W-K;
- Minvielle, S;
- Broyl, A;
- Li, Y;
- Hanlon, B;
- Swanson, D;
- Shah, P K;
- Moreau, P;
- van der Holt, B;
- van Duin, M;
- Magrangeas, F;
- Pieter Sonneveld, P;
- Anderson, K C;
- Li, C;
- Avet-Loiseau, H;
- Munshi, N C
Publication type:
Article

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