Works matching IS 08876924 AND DT 2014 AND VI 28 AND IP 1

Results: 48

Dasatinib promotes the potential of proliferation and antitumor responses of human γδT cells in a long-term induction ex vivo environment.

Published in:

2014

By:

Wu, K-N;
Wang, Y-J;
He, Y;
Hu, Y-X;
Fu, H-R;
Sheng, L-X;
Wang, B-S;
Fu, S;
Huang, H

Publication type:

Letter

Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia.

Published in:

2014

By:

Allegra, D;
Bilan, V;
Garding, A;
Döhner, H;
Stilgenbauer, S;
Kuchenbauer, F;
Mertens, D;
Zucknick, M

Publication type:

journal article

Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system.

Published in:

2014

By:

Arndt, C;
Feldmann, A;
von Bonin, M;
Cartellieri, M;
Ewen, E-M;
Koristka, S;
Michalk, I;
Stamova, S;
Berndt, N;
Gocht, A;
Bornhäuser, M;
Ehninger, G;
Schmitz, M;
Bachmann, M

Publication type:

journal article

Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance.

Published in:

2014

By:

Hillengass, J;
Weber, M-A;
Kilk, K;
Listl, K;
Wagner-Gund, B;
Hillengass, M;
Hielscher, T;
Farid, A;
Neben, K;
Delorme, S;
Landgren, O;
Goldschmidt, H

Publication type:

journal article

Origins of aberrant DNA methylation in acute myeloid leukemia.

Published in:

2014

By:

Schoofs, T;
Berdel, W E;
Müller-Tidow, C

Publication type:

journal article

Understanding the mutational evolution of clonal cytopenias and oligoblastic myelogenous leukemia ('myelodysplasia').

Published in:

2014

By:

Lichtman, M A

Publication type:

Letter

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

Published in:

2014

By:

McCubrey, J A;
Steelman, L S;
Bertrand, F E;
Davis, N M;
Abrams, S L;
Montalto, G;
D'Assoro, A B;
Libra, M;
Nicoletti, F;
Maestro, R;
Basecke, J;
Cocco, L;
Cervello, M;
Martelli, A M

Publication type:

journal article

Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 129, doi. 10.1038/leu.2013.239

By:

Kohlmann, A;
Nadarajah, N;
Alpermann, T;
Grossmann, V;
Schindela, S;
Dicker, F;
Roller, A;
Kern, W;
Haferlach, C;
Schnittger, S;
Haferlach, T

Publication type:

Article

Efficient generation of human natural killer cell lines by viral transformation.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 192, doi. 10.1038/leu.2013.188

By:

Vogel, B;
Tennert, K;
Full, F;
Ensser, A

Publication type:

Article

Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 98, doi. 10.1038/leu.2013.246

By:

Allegra, D;
Bilan, V;
Garding, A;
Döhner, H;
Stilgenbauer, S;
Kuchenbauer, F;
Mertens, D

Publication type:

Article

Loss of p53 and altered miR15-a/16-1MCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells.

Published in:

2014

By:

Liu, J;
Chen, G;
Feng, L;
Zhang, W;
Pelicano, H;
Wang, F;
Ogasawara, M A;
Lu, W;
Amin, H M;
Croce, C M;
Keating, M J;
Huang, P

Publication type:

journal article

Regulation of MEIS1 by distal enhancer elements in acute leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 138, doi. 10.1038/leu.2013.260

By:

Wang, Q-f;
Li, Y-j;
Dong, J-f;
Li, B;
Kaberlein, J J;
Zhang, L;
Arimura, F E;
Luo, R T;
Ni, J;
He, F;
Wu, J;
Mattison, R;
Zhou, J;
Wang, C-z;
Prabhakar, S;
Nobrega, M A;
Thirman, M J

Publication type:

Article

Multiparameter flow cytometry for the identification of the Waldenström's clone in IgM-MGUS and Waldenström's Macroglobulinemia: new criteria for differential diagnosis and risk stratification.

Published in:

2014

By:

Paiva, B;
Montes, M C;
García-Sanz, R;
Ocio, E M;
Alonso, J;
de Las Heras, N;
Escalante, F;
Cuello, R;
de Coca, A G;
Galende, J;
Hernández, J;
Sierra, M;
Martin, A;
Pardal, E;
Bárez, A;
Suarez, L;
González-López, T J;
Perez, J J;
Orfao, A;
Vidríales, M-B

Publication type:

journal article

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.

Published in:

2014

By:

Tai, Y-T;
Landesman, Y;
Acharya, C;
Calle, Y;
Zhong, M Y;
Cea, M;
Tannenbaum, D;
Cagnetta, A;
Reagan, M;
Munshi, A A;
Senapedis, W;
Saint-Martin, J-R;
Kashyap, T;
Shacham, S;
Kauffman, M;
Gu, Y;
Wu, L;
Ghobrial, I;
Zhan, F;
Kung, A L

Publication type:

journal article

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 15, doi. 10.1038/leu.2013.184

By:

McCubrey, J A;
Steelman, L S;
Bertrand, F E;
Davis, N M;
Abrams, S L;
Montalto, G;
D'Assoro, A B;
Libra, M;
Nicoletti, F;
Maestro, R;
Basecke, J;
Cocco, L;
Cervello, M;
Martelli, A M

Publication type:

Article

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 189, doi. 10.1038/leu.2013.195

By:

Aalbers, A M;
van der Velden, V H J;
Yoshimi, A;
Fischer, A;
Noellke, P;
Zwaan, C M;
Baumann, I;
Beverloo, H B;
Dworzak, M;
Hasle, H;
Locatelli, F;
De Moerloose, B;
Göhring, G;
Schmugge, M;
Stary, J;
Zecca, M;
Langerak, A W;
van Dongen, J J M;
Pieters, R;
Niemeyer, C M

Publication type:

Article

PAX5 overexpression is not enough to reestablish the mature B-cell phenotype in classical Hodgkin lymphoma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 213, doi. 10.1038/leu.2013.211

By:

Dimitrova, L;
Seitz, V;
Hecht, J;
Lenze, D;
Hansen, P;
Szczepanowski, M;
Ma, L;
Oker, E;
Sommerfeld, A;
Jundt, F;
Klapper, W;
Hummel, M

Publication type:

Article

Application of the International Prognostic Scoring System-Revised in therapy-related myelodysplastic syndromes and oligoblastic acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 185, doi. 10.1038/leu.2013.191

By:

Ok, C Y;
Hasserjian, R P;
Fox, P S;
Stingo, F;
Zuo, Z;
Young, K H;
Patel, K;
Medeiros, L J;
Garcia-Manero, G;
Wang, S A

Publication type:

Article

Multiparameter flow cytometry for the identification of the Waldenström's clone in IgM-MGUS and Waldenström's Macroglobulinemia: new criteria for differential diagnosis and risk stratification.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 166, doi. 10.1038/leu.2013.124

By:

Paiva, B;
Montes, M C;
García-Sanz, R;
Ocio, E M;
Alonso, J;
de las Heras, N;
Escalante, F;
Cuello, R;
de Coca, A G;
Galende, J;
Hernández, J;
Sierra, M;
Martin, A;
Pardal, E;
Bárez, A;
Suarez, L;
González-López, T J;
Perez, J J;
Orfao, A;
Vidríales, M-B

Publication type:

Article

Origins of aberrant DNA methylation in acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 1, doi. 10.1038/leu.2013.242

By:

Schoofs, T;
Berdel, W E;
Müller-Tidow, C

Publication type:

Article

Detecting dic(9;20)(p13.2;p11.2)-positive B-cell precursor acute lymphoblastic leukemia in a clinical setting using fluorescence in situ hybridization.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 196, doi. 10.1038/leu.2013.189

By:

Zachariadis, V;
Schoumans, J;
Öfverholm, I;
Barbany, G;
Halvardsson, E;
Forestier, E;
Johansson, B;
Nordenskjöld, M;
Nordgren, A

Publication type:

Article

Understanding the mutational evolution of clonal cytopenias and oligoblastic myelogenous leukemia ('myelodysplasia').

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 202, doi. 10.1038/leu.2013.209

By:

Lichtman, M A

Publication type:

Article

mTOR kinase inhibitor sensitizes T-cell lymphoblastic leukemia for chemotherapy-induced DNA damage via suppressing FANCD2 expression.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 203, doi. 10.1038/leu.2013.215

By:

Guo, F;
Li, J;
Zhang, S;
Du, W;
Amarachintha, S;
Sipple, J;
Phelan, J;
Grimes, H L;
Zheng, Y;
Pang, Q

Publication type:

Article

Bilateral corneal infections associated with topical steroid therapy prophylaxis for cytarabine arabinoside-induced keratoconjunctivitis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 220, doi. 10.1038/leu.2013.237

By:

Samarawickrama, C;
Ioannidis, A S;
Wechsler, A W;
Watson, S L

Publication type:

Article

Expression of the lymphoid enhancer factor 1 is required for normal hematopoietic stem and progenitor cell function.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 227, doi. 10.1038/leu.2013.238

By:

Edmaier, K E;
Stahnke, K;
Vegi, N;
Mulaw, M;
Ihme, S;
Scheffold, A;
Rudolph, K L;
Buske, C

Publication type:

Article

VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 216, doi. 10.1038/leu.2013.223

By:

Mangum, D S;
Downie, J;
Mason, C C;
Jahromi, M S;
Joshi, D;
Rodic, V;
Müschen, M;
Meeker, N;
Trede, N;
Frazer, J K;
Zhou, Y;
Cheng, C;
Jeha, S;
Pui, C-H;
Willman, C L;
Harvey, R C;
Hunger, S P;
Yang, J J;
Barnette, P;
Mullighan, C G

Publication type:

Article

BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 88, doi. 10.1038/leu.2013.234

By:

Wyspiańska, B S;
Bannister, A J;
Barbieri, I;
Nangalia, J;
Godfrey, A;
Calero-Nieto, F J;
Robson, S;
Rioja, I;
Li, J;
Wiese, M;
Cannizzaro, E;
Dawson, M A;
Huntly, B;
Prinjha, R K;
Green, A R;
Gottgens, B;
Kouzarides, T

Publication type:

Article

The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 210, doi. 10.1038/leu.2013.216

By:

Touzeau, C;
Dousset, C;
Le Gouill, S;
Sampath, D;
Leverson, J D;
Souers, A J;
Maïga, S;
Béné, M C;
Moreau, P;
Pellat-Deceunynck, C;
Amiot, M

Publication type:

Article

Clonal evolution in hematological malignancies and therapeutic implications.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 34, doi. 10.1038/leu.2013.248

By:

Landau, D A;
Carter, S L;
Getz, G;
Wu, C J

Publication type:

Article

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 182, doi. 10.1038/leu.2013.282

By:

Zaliova, M;
Zimmermannova, O;
Dörge, P;
Eckert, C;
Möricke, A;
Zimmermann, M;
Stuchly, J;
Teigler-Schlegel, A;
Meissner, B;
Koehler, R;
Bartram, C R;
Karawajew, L;
Rhein, P;
Zuna, J;
Schrappe, M;
Cario, G;
Stanulla, M

Publication type:

Article

Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 236, doi. 10.1038/leu.2013.261

By:

Ahmad, S M;
Larsen, S K;
Svane, I M;
Andersen, M H

Publication type:

Article

Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 198, doi. 10.1038/leu.2013.204

By:

Oyer, J A;
Huang, X;
Zheng, Y;
Shim, J;
Ezponda, T;
Carpenter, Z;
Allegretta, M;
Okot-Kotber, C I;
Patel, J P;
Melnick, A;
Levine, R L;
Ferrando, A;
MacKerell, A D;
Kelleher, N L;
Licht, J D;
Popovic, R

Publication type:

Article

Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 230, doi. 10.1038/leu.2013.240

By:

Le Garff-Tavernier, M;
Herbi, L;
de Romeuf, C;
Nguyen-Khac, F;
Davi, F;
Grelier, A;
Boudjoghra, M;
Maloum, K;
Choquet, S;
Urbain, R;
Vieillard, V;
Merle-Béral, H

Publication type:

Article

Overexpression of SNORD114-3 marks acute promyelocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 233, doi. 10.1038/leu.2013.250

By:

Liuksiala, T;
Teittinen, K J;
Granberg, K;
Heinäniemi, M;
Annala, M;
Mäki, M;
Nykter, M;
Lohi, O

Publication type:

Article

Reactivation of hepatitis B virus infection following ruxolitinib treatment in a patient with myelofibrosis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 225, doi. 10.1038/leu.2013.235

By:

Caocci, G;
Murgia, F;
Podda, L;
Solinas, A;
Atzeni, S;
La Nasa, G

Publication type:

Article

Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 50, doi. 10.1038/leu.2013.236

By:

Hou, H-A;
Lin, C-C;
Chou, W-C;
Liu, C-Y;
Chen, C-Y;
Tang, J-L;
Lai, Y-J;
Tseng, M-H;
Huang, C-F;
Chiang, Y-C;
Lee, F-Y;
Kuo, Y-Y;
Lee, M-C;
Liu, M-C;
Liu, C-W;
Lin, L-I;
Yao, M;
Huang, S-Y;
Ko, B-S;
Hsu, S-C

Publication type:

Article

SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 108, doi. 10.1038/leu.2013.263

By:

Jeromin, S;
Weissmann, S;
Haferlach, C;
Dicker, F;
Bayer, K;
Grossmann, V;
Alpermann, T;
Roller, A;
Kohlmann, A;
Haferlach, T;
Kern, W;
Schnittger, S

Publication type:

Article

Dasatinib promotes the potential of proliferation and antitumor responses of human γδT cells in a long-term induction ex vivo environment.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 206, doi. 10.1038/leu.2013.221

By:

Wu, K-n;
Wang, Y-j;
He, Y;
Hu, Y-x;
Fu, H-r;
Sheng, L-x;
Wang, B-s;
Fu, S;
Huang, H

Publication type:

Article

Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 78, doi. 10.1038/leu.2013.269

By:

Traina, F;
Visconte, V;
Elson, P;
Tabarroki, A;
Jankowska, A M;
Hasrouni, E;
Sugimoto, Y;
Szpurka, H;
Makishima, H;
O'Keefe, C L;
Sekeres, M A;
Advani, A S;
Kalaycio, M;
Copelan, E A;
Saunthararajah, Y;
Olalla Saad, S T;
Maciejewski, J P;
Tiu, R V

Publication type:

Article

Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 174, doi. 10.1038/leu.2013.244

By:

Hillengass, J;
Weber, M-A;
Kilk, K;
Listl, K;
Wagner-Gund, B;
Hillengass, M;
Hielscher, T;
Farid, A;
Neben, K;
Delorme, S;
Landgren, O;
Goldschmidt, H

Publication type:

Article

Epigenetic mechanisms of protein tyrosine phosphatase 6 suppression in diffuse large B-cell lymphoma: implications for epigenetic therapy.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 147, doi. 10.1038/leu.2013.251

By:

Witzig, T E;
Hu, G;
Offer, S M;
Wellik, L E;
Han, J J;
Stenson, M J;
Dogan, A;
Diasio, R B;
Gupta, M

Publication type:

Article

Loss of p53 and altered miR15-a/16-1MCL-1 pathway in CLL: insights from TCL1-Tg:p53<sup>−/−</sup> mouse model and primary human leukemia cells.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 118, doi. 10.1038/leu.2013.125

By:

Liu, J;
Chen, G;
Feng, L;
Zhang, W;
Pelicano, H;
Wang, F;
Ogasawara, M A;
Lu, W;
Amin, H M;
Croce, C M;
Keating, M J;
Huang, P

Publication type:

Article

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 155, doi. 10.1038/leu.2013.115

By:

Tai, Y-T;
Landesman, Y;
Acharya, C;
Calle, Y;
Zhong, M Y;
Cea, M;
Tannenbaum, D;
Cagnetta, A;
Reagan, M;
Munshi, A A;
Senapedis, W;
Saint-Martin, J-R;
Kashyap, T;
Shacham, S;
Kauffman, M;
Gu, Y;
Wu, L;
Ghobrial, I;
Zhan, F;
Kung, A L

Publication type:

Article

Lenalidomide and low-dose dexamethasone for newly diagnosed primary plasma cell leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 222, doi. 10.1038/leu.2013.241

By:

Musto, P;
Simeon, V;
Martorelli, M C;
Petrucci, M T;
Cascavilla, N;
Di Raimondo, F;
Caravita, T;
Morabito, F;
Offidani, M;
Olivieri, A;
Benevolo, G;
Mina, R;
Guariglia, R;
D'Arena, G;
Mansueto, G;
Filardi, N;
Nobile, F;
Levi, A;
Falcone, A;
Cavalli, M

Publication type:

Article

An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 70, doi. 10.1038/leu.2013.277

By:

Clappier, E;
Auclerc, M-F;
Rapion, J;
Bakkus, M;
Caye, A;
Khemiri, A;
Giroux, C;
Hernandez, L;
Kabongo, E;
Savola, S;
Leblanc, T;
Yakouben, K;
Plat, G;
Costa, V;
Ferster, A;
Girard, S;
Fenneteau, O;
Cayuela, J-M;
Sigaux, F;
Dastugue, N

Publication type:

Article

EZH2 in normal and malignant hematopoiesis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 44, doi. 10.1038/leu.2013.288

By:

Lund, K;
Adams, P D;
Copland, M

Publication type:

Article

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 179, doi. 10.1038/leu.2013.232

By:

Martins, L R;
Lúcio, P;
Melão, A;
Antunes, I;
Cardoso, B A;
Stansfield, R;
Bertilaccio, M T S;
Ghia, P;
Drygin, D;
Silva, M G;
Barata, J T

Publication type:

Article

Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 59, doi. 10.1038/leu.2013.243

By:

Arndt, C;
Feldmann, A;
von Bonin, M;
Cartellieri, M;
Ewen, E-M;
Koristka, S;
Michalk, I;
Stamova, S;
Berndt, N;
Gocht, A;
Bornhäuser, M;
Ehninger, G;
Schmitz, M;
Bachmann, M

Publication type:

Article