Works matching IS 08876924 AND DT 2013 AND VI 27 AND IP 6

Results: 43

The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib.

Published in:

2013

By:

Albers, C;
Leischner, H;
Verbeek, M;
Yu, C;
Illert, A L;
Peschel, C;
von Bubnoff, N;
Duyster, J

Publication type:

Case Study

Risk of acute leukemia and myelodysplastic syndromes in patients with monoclonal gammopathy of undetermined significance (MGUS): a population-based study of 17 315 patients.

Published in:

2013

By:

Roeker, L E;
Larson, D R;
Kyle, R A;
Kumar, S;
Dispenzieri, A;
Rajkumar, S V

Publication type:

journal article

Increased circulating IL-2R[alpha] (CD25) predicts poor outcome in both indolent and aggressive forms of mastocytosis: a comprehensive cytokine-phenotype study.

Published in:

2013

By:

Pardanani, A;
Finke, C;
Abdelrahman, R A;
Lasho, T L;
Hanson, C A;
Tefferi, A

Publication type:

Journal Article

γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia.

Published in:

2013

By:

Scheper, W;
van Dorp, S;
Kersting, S;
Pietersma, F;
Lindemans, C;
Hol, S;
Heijhuurs, S;
Sebestyen, Z;
Gründer, C;
Marcu-Malina, V;
Marchant, A;
Donner, C;
Plachter, B;
Vermijlen, D;
van Baarle, D;
Kuball, J

Publication type:

journal article

ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells.

Published in:

2013

By:

Chee, L C Y;
Hendy, J;
Purton, L E;
McArthur, G A

Publication type:

journal article

Lenalidomide-induced upregulation of CXCR4 in CD34+ hematopoietic cells, a potential mechanism of decreased hematopoietic progenitor mobilization.

Published in:

2013

By:

Li, S;
Fu, J;
Ma, H;
Mapara, M Y;
Lentzsch, S

Publication type:

Letter

Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome--positive acute lymphoblastic leukemia.

Published in:

2013

By:

Ottmann, O G;
Larson, R A;
Kantarjian, H M;
le Coutre, P D;
Baccarani, M;
Hochhaus, A;
Kim, D W;
Fan, X;
Novick, S;
Giles, F J

Publication type:

clinical trial

Risk of acute leukemia and myelodysplastic syndromes in patients with monoclonal gammopathy of undetermined significance (MGUS): a population-based study of 17 315 patients.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1391, doi. 10.1038/leu.2013.34

By:

Roeker, L E;
Larson, D R;
Kyle, R A;
Kumar, S;
Dispenzieri, A;
Rajkumar, S V

Publication type:

Article

Randomized comparison of prophylactic and minimal residual disease-triggered imatinib after allogeneic stem cell transplantation for BCR-ABL1-positive acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1254, doi. 10.1038/leu.2012.352

By:

Pfeifer, H;
Wassmann, B;
Bethge, W;
Dengler, J;
Bornhäuser, M;
Stadler, M;
Beelen, D;
Vucinic, V;
Burmeister, T;
Stelljes, M;
Faul, C;
Dreger, P;
Kiani, A;
Schäfer-Eckart, K;
Schwerdtfeger, R;
Lange, E;
Kubuschok, B;
Horst, H A;
Gramatzki, M;
Brück, P

Publication type:

Article

AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1339, doi. 10.1038/leu.2013.33

By:

Stankiewicz, M J;
Crispino, J D

Publication type:

Article

Genome-wide profiling reveals epigenetic inactivation of the PU.1 pathway by histone H3 lysine 27 trimethylation in cytogenetically normal myelodysplastic syndrome.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1291, doi. 10.1038/leu.2013.45

By:

Cheng, J X;
Anastasi, J;
Watanabe, K;
Kleinbrink, E L;
Grimley, E;
Knibbs, R;
Shen, Q J;
Vardiman, J W

Publication type:

Article

A novel recurrent AML1-ETO fusion: tight in vivo association with BCR-ABL1.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1397, doi. 10.1038/leu.2013.53

By:

Solari, L;
Bauer, T;
Dicker, F;
Haferlach, C;
Grießhammer, M;
Schnittger, S;
Becker, H;
Lübbert, M

Publication type:

Article

Increased circulating IL-2Rα (CD25) predicts poor outcome in both indolent and aggressive forms of mastocytosis: a comprehensive cytokine-phenotype study.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1430, doi. 10.1038/leu.2013.11

By:

Pardanani, A;
Finke, C;
Abdelrahman, R A;
Lasho, T L;
Hanson, C A;
Tefferi, A

Publication type:

Article

Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1301, doi. 10.1038/leu.2013.80

By:

Khan, S N;
Jankowska, A M;
Mahfouz, R;
Dunbar, A J;
Sugimoto, Y;
Hosono, N;
Hu, Z;
Cheriyath, V;
Vatolin, S;
Przychodzen, B;
Reu, F J;
Saunthararajah, Y;
O'Keefe, C;
Sekeres, M A;
List, A F;
Moliterno, A R;
McDevitt, M A;
Maciejewski, J P;
Makishima, H

Publication type:

Article

Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1263, doi. 10.1038/leu.2013.5

By:

Matlawska-Wasowska, K;
Ward, E;
Stevens, S;
Wang, Y;
Herbst, R;
Winter, S S;
Wilson, B S

Publication type:

Article

Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1236, doi. 10.1038/leu.2013.9

By:

Spagnuolo, P A;
Hurren, R;
Gronda, M;
MacLean, N;
Datti, A;
Basheer, A;
Lin, F-H;
Wang, X;
Wrana, J;
Schimmer, A D

Publication type:

Article

Myelofibrosis, JAK2 inhibitors and erythropoiesis.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1219, doi. 10.1038/leu.2013.72

By:

Vainchenker, W;
Favale, F

Publication type:

Article

Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1316, doi. 10.1038/leu.2013.70

By:

Kim, T D;
Rea, D;
Schwarz, M;
Grille, P;
Nicolini, F E;
Rosti, G;
Levato, L;
Giles, F J;
Dombret, H;
Mirault, T;
Labussière, H;
Lindhorst, R;
Haverkamp, W;
Buschmann, I;
Dörken, B;
le Coutre, P D

Publication type:

Article

The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD<sup>+</sup> AML but retains in vitro sensitivity to PKC412 and Sunitinib.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1416, doi. 10.1038/leu.2013.14

By:

Albers, C;
Leischner, H;
Verbeek, M;
Yu, C;
Illert, A L;
Peschel, C;
von Bubnoff, N;
Duyster, J

Publication type:

Article

Acute lymphoblastic leukemia associated with RCSD1-ABL1 novel fusion gene has a distinct gene expression profile from BCR-ABL1 fusion.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1422, doi. 10.1038/leu.2012.332

By:

De Braekeleer, E;
Douet-Guilbert, N;
Guardiola, P;
Rowe, D;
Mustjoki, S;
Zamecnikova, A;
Al Bahar, S;
Jaramillo, G;
Berthou, C;
Bown, N;
Porkka, K;
Ochoa, C;
De Braekeleer, M

Publication type:

Article

ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1369, doi. 10.1038/leu.2012.362

By:

Chee, L C Y;
Hendy, J;
Purton, L E;
McArthur, G A

Publication type:

Article

Impairing MLL-fusion gene-mediated transformation by dissecting critical interactions with the lens epithelium-derived growth factor (LEDGF/p75).

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1245, doi. 10.1038/leu.2013.10

By:

Méreau, H;
De Rijck, J;
Čermáková, K;
Kutz, A;
Juge, S;
Demeulemeester, J;
Gijsbers, R;
Christ, F;
Debyser, Z;
Schwaller, J

Publication type:

Article

Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1433, doi. 10.1038/leu.2012.333

By:

Chonabayashi, K;
Hishizawa, M;
Kawamata, S;
Nagai, Y;
Ohno, T;
Ishikawa, T;
Uchiyama, T;
Takaori-Kondo, A

Publication type:

Article

Sequential combination of azacitidine and lenalidomide in del(5q) higher-risk myelodysplastic syndromes or acute myeloid leukemia: a phase I study.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1403, doi. 10.1038/leu.2013.26

By:

Platzbecker, U;
Braulke, F;
Kündgen, A;
Götze, K;
Bug, G;
Schönefeldt, C;
Shirneshan, K;
Röllig, C;
Bornhäuser, M;
Naumann, R;
Neesen, J;
Giagounidis, A;
Hofmann, W-K;
Ehninger, G;
Germing, U;
Haase, D;
Wermke, M

Publication type:

Article

HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1358, doi. 10.1038/leu.2012.366

By:

Zhou, L;
Ruvolo, V R;
McQueen, T;
Chen, W;
Samudio, I J;
Conneely, O;
Konopleva, M;
Andreeff, M

Publication type:

Article

Clonal diversity of recurrently mutated genes in myelodysplastic syndromes.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1275, doi. 10.1038/leu.2013.58

By:

Walter, M J;
Shen, D;
Shao, J;
Ding, L;
White, B S;
Kandoth, C;
Miller, C A;
Niu, B;
McLellan, M D;
Dees, N D;
Fulton, R;
Elliot, K;
Heath, S;
Grillot, M;
Westervelt, P;
Link, D C;
DiPersio, J F;
Mardis, E;
Ley, T J;
Wilson, R K

Publication type:

Article

γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1328, doi. 10.1038/leu.2012.374

By:

Scheper, W;
van Dorp, S;
Kersting, S;
Pietersma, F;
Lindemans, C;
Hol, S;
Heijhuurs, S;
Sebestyen, Z;
Gründer, C;
Marcu-Malina, V;
Marchant, A;
Donner, C;
Plachter, B;
Vermijlen, D;
van Baarle, D;
Kuball, J

Publication type:

Article

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1348, doi. 10.1038/leu.2013.2

By:

Oram, S H;
Thoms, J;
Sive, J I;
Calero-Nieto, F J;
Kinston, S J;
Schütte, J;
Knezevic, K;
Lock, R B;
Pimanda, J E;
Göttgens, B

Publication type:

Article

Secondary mutations in t(4;11) leukemia patients.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1425, doi. 10.1038/leu.2012.365

By:

Prelle, C;
Bursen, A;
Dingermann, T;
Marschalek, R

Publication type:

Article

Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1411, doi. 10.1038/leu.2012.324

By:

Ottmann, O G;
Larson, R A;
Kantarjian, H M;
le Coutre, P D;
Baccarani, M;
Hochhaus, A;
Kim, D W;
Fan, X;
Novick, S;
Giles, F J

Publication type:

Article

Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1310, doi. 10.1038/leu.2013.69

By:

Giles, F J;
Mauro, M J;
Hong, F;
Ortmann, C-E;
McNeill, C;
Woodman, R C;
Hochhaus, A;
le Coutre, P D;
Saglio, G

Publication type:

Article

Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1322, doi. 10.1038/leu.2013.71

By:

Pardanani, A;
Laborde, R R;
Lasho, T L;
Finke, C;
Begna, K;
Al-Kali, A;
Hogan, W J;
Litzow, M R;
Leontovich, A;
Kowalski, M;
Tefferi, A

Publication type:

Article

Long-term outcome of anemic lower-risk myelodysplastic syndromes without 5q deletion refractory to or relapsing after erythropoiesis-stimulating agents.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1283, doi. 10.1038/leu.2013.16

By:

Kelaidi, C;
Park, S;
Sapena, R;
Beyne-Rauzy, O;
Coiteux, V;
Vey, N;
Stamatoullas, A;
Choufi, B;
Delaunay, J;
Gourin, M-P;
Cheze, S;
Ravoet, C;
Ferrant, A;
Escoffre-Barbe, M;
Aljassem, L;
Raffoux, E;
Itzykson, R;
Adès, L;
Dreyfus, F;
Fenaux, P

Publication type:

Article

In focus: MLL-rearranged leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1224, doi. 10.1038/leu.2013.78

By:

de Boer, J;
Walf-Vorderwülbecke, V;
Williams, O

Publication type:

Article

Azacitidine and donor lymphocyte infusions as first salvage therapy for relapse of AML or MDS after allogeneic stem cell transplantation.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1229, doi. 10.1038/leu.2013.7

By:

Schroeder, T;
Czibere, A;
Platzbecker, U;
Bug, G;
Uharek, L;
Luft, T;
Giagounidis, A;
Zohren, F;
Bruns, I;
Wolschke, C;
Rieger, K;
Fenk, R;
Germing, U;
Haas, R;
Kröger, N;
Kobbe, G

Publication type:

Article

Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1427, doi. 10.1038/leu.2013.47

By:

Kok, C H;
Watkins, D B;
Leclercq, T;
D'Andrea, R J;
Hughes, T P;
White, D L

Publication type:

Article

Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1437, doi. 10.1038/leu.2012.337

By:

Yost, A J;
Shevchuk, O O;
Gooch, R;
Gusscott, S;
You, M J;
Ince, T A;
Aster, J C;
Weng, A P

Publication type:

Article

Nurse-like cells control the activity of chronic lymphocytic leukemia B cells via galectin-1.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1413, doi. 10.1038/leu.2012.315

By:

Croci, D O;
Morande, P E;
Dergan-Dylon, S;
Borge, M;
Toscano, M A;
Stupirski, J C;
Bezares, R F;
Avalos, J S;
Narbaitz, M;
Gamberale, R;
Rabinovich, G A;
Giordano, M

Publication type:

Article

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1381, doi. 10.1038/leu.2012.367

By:

Wenzel, S-S;
Grau, M;
Mavis, C;
Hailfinger, S;
Wolf, A;
Madle, H;
Deeb, G;
Dörken, B;
Thome, M;
Lenz, P;
Dirnhofer, S;
Hernandez-Ilizaliturri, F J;
Tzankov, A;
Lenz, G

Publication type:

Article

Lenalidomide-induced upregulation of CXCR4 in CD34<sup>+</sup> hematopoietic cells, a potential mechanism of decreased hematopoietic progenitor mobilization.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1407, doi. 10.1038/leu.2012.323

By:

Li, S;
Fu, J;
Ma, H;
Mapara, M Y;
Lentzsch, S

Publication type:

Article

A response-adjusted PET-based transplantation strategy in primary resistant and relapsed Hodgkin Lymphoma.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1419, doi. 10.1038/leu.2012.318

By:

Thomson, K J;
Kayani, I;
Ardeshna, K;
Morris, E C;
Hough, R;
Virchis, A;
Goldstone, A H;
Linch, D C;
Peggs, K S

Publication type:

Article

SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1401, doi. 10.1038/leu.2013.35

By:

Damm, F;
Itzykson, R;
Kosmider, O;
Droin, N;
Renneville, A;
Chesnais, V;
Gelsi-Boyer, V;
de Botton, S;
Vey, N;
Preudhomme, C;
Clavert, A;
Delabesse, E;
Park, S;
Birnbaum, D;
Fontenay, M;
Bernard, O A;
Solary, E

Publication type:

Article

Comparison of outcomes between autologous and allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphomas with central review of pathology.

Published in:

Leukemia (08876924), 2013, v. 27, n. 6, p. 1394, doi. 10.1038/leu.2012.321

By:

Kim, S-W;
Yoon, S-S;
Suzuki, R;
Matsuno, Y;
Yi, H G;
Yoshida, T;
Imamura, M;
Wake, A;
Miura, K;
Hino, M;
Ishikawa, T;
Kim, J S;
Maeda, Y;
Lee, J-J;
Kang, H J;
Lee, H S;
Lee, J-H;
Izutsu, K;
Fukuda, T;
Kim, C W

Publication type:

Article