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Results: 29

Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
Published in:
2012
By:
- Hanfstein B;
- Müller MC;
- Hehlmann R;
- Erben P;
- Lauseker M;
- Fabarius A;
- Schnittger S;
- Haferlach C;
- Göhring G;
- Proetel U;
- Kolb HJ;
- Krause SW;
- Hofmann WK;
- Schubert J;
- Einsele H;
- Dengler J;
- Hänel M;
- Falge C;
- Kanz L;
- Neubauer A
Publication type:
Journal Article
EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols.
Published in:
2012
By:
- Kalina T;
- Flores-Montero J;
- van der Velden VH;
- Martin-Ayuso M;
- Böttcher S;
- Ritgen M;
- Almeida J;
- Lhermitte L;
- Asnafi V;
- Mendonça A;
- de Tute R;
- Cullen M;
- Sedek L;
- Vidriales MB;
- Pérez JJ;
- te Marvelde JG;
- Mejstrikova E;
- Hrusak O;
- Szczepanski T;
- van Dongen JJ
Publication type:
journal article
Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells.
Published in:
2012
By:
- Coles SJ;
- Hills RK;
- Wang EC;
- Burnett AK;
- Man S;
- Darley RL;
- Tonks A;
- Coles, S J;
- Hills, R K;
- Wang, E C Y;
- Burnett, A K;
- Man, S;
- Darley, R L;
- Tonks, A
Publication type:
Letter
Retention of CD34+ CML stem/progenitor cells during imatinib treatment and rapid decline after treatment with second-generation BCR-ABL inhibitors.
Published in:
2012
By:
- Minami Y;
- Abe A;
- Minami M;
- Kitamura K;
- Hiraga J;
- Mizuno S;
- Ymamoto K;
- Sawa M;
- Inagaki Y;
- Miyamura K;
- Naoe T;
- Minami, Y;
- Abe, A;
- Minami, M;
- Kitamura, K;
- Hiraga, J;
- Mizuno, S;
- Ymamoto, K;
- Sawa, M;
- Inagaki, Y
Publication type:
Letter
Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2114, doi. 10.1038/leu.2012.71
By:
- Yang, J;
- He, J;
- Wang, J;
- Cao, Y;
- Ling, J;
- Qian, J;
- Lu, Y;
- Li, H;
- Zheng, Y;
- Lan, Y;
- Hong, S;
- Matthews, J;
- Starbuck, M W;
- Navone, N M;
- Orlowski, R Z;
- Lin, P;
- Kwak, L W;
- Yi, Q
Publication type:
Article
MiR-125 in normal and malignant hematopoiesis.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2011, doi. 10.1038/leu.2012.90
By:
- Shaham, L;
- Binder, V;
- Gefen, N;
- Borkhardt, A;
- Izraeli, S
Publication type:
Article
Retention of CD34<sup>+</sup> CML stem/progenitor cells during imatinib treatment and rapid decline after treatment with second-generation BCR-ABL inhibitors.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2142, doi. 10.1038/leu.2012.73
By:
- Minami, Y;
- Abe, A;
- Minami, M;
- Kitamura, K;
- Hiraga, J;
- Mizuno, S;
- Ymamoto, K;
- Sawa, M;
- Inagaki, Y;
- Miyamura, K;
- Naoe, T
Publication type:
Article
EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 1986, doi. 10.1038/leu.2012.122
By:
- Kalina, T;
- Flores-Montero, J;
- van der Velden, V H J;
- Martin-Ayuso, M;
- Böttcher, S;
- Ritgen, M;
- Almeida, J;
- Lhermitte, L;
- Asnafi, V;
- Mendonça, A;
- de Tute, R;
- Cullen, M;
- Sedek, L;
- Vidriales, M B;
- Pérez, J J;
- te Marvelde, J G;
- Mejstrikova, E;
- Hrusak, O;
- Szczepański, T;
- van Dongen, J J M
Publication type:
Article
Spliceosome and other novel mutations in chronic lymphocytic leukemia and myeloid malignancies.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2027, doi. 10.1038/leu.2012.86
By:
- Damm, F;
- Nguyen-Khac, F;
- Fontenay, M;
- Bernard, O A
Publication type:
Article
Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2154, doi. 10.1038/leu.2012.82
By:
- Yip, B H;
- Pellagatti, A;
- Vuppusetty, C;
- Giagounidis, A;
- Germing, U;
- Lamikanra, A A;
- Roberts, D J;
- Fernandez-Mercado, M;
- McDonald, E-J;
- Killick, S;
- Wainscoat, J S;
- Boultwood, J
Publication type:
Article
Small molecule antibody targeting HLA class I inhibits myeloma cancer stem cells by repressing pluripotency-associated transcription factors.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2124, doi. 10.1038/leu.2012.78
By:
- Ikegame, A;
- Ozaki, S;
- Tsuji, D;
- Harada, T;
- Fujii, S;
- Nakamura, S;
- Miki, H;
- Nakano, A;
- Kagawa, K;
- Takeuchi, K;
- Abe, M;
- Watanabe, K;
- Hiasa, M;
- Kimura, N;
- Kikuchi, Y;
- Sakamoto, A;
- Habu, K;
- Endo, M;
- Itoh, K;
- Yamada-Okabe, H
Publication type:
Article
Pretransplant HLA mistyping in diagnostic samples of acute myeloid leukemia patients due to acquired uniparental disomy.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2079, doi. 10.1038/leu.2012.68
By:
- Dubois, V;
- Sloan-Béna, F;
- Cesbron, A;
- Hepkema, B G;
- Gagne, K;
- Gimelli, S;
- Heim, D;
- Tichelli, A;
- Delaunay, J;
- Drouet, M;
- Jendly, S;
- Villard, J;
- Tiercy, J-M
Publication type:
Article
Natural killer cell immune escape in acute myeloid leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2019, doi. 10.1038/leu.2012.87
By:
- Lion, E;
- Willemen, Y;
- Berneman, Z N;
- Van Tendeloo, V F I;
- Smits, E L J
Publication type:
Article
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2039, doi. 10.1038/leu.2012.157
By:
- Sprüssel, A;
- Schulte, J H;
- Weber, S;
- Necke, M;
- Händschke, K;
- Thor, T;
- Pajtler, K W;
- Schramm, A;
- König, K;
- Diehl, L;
- Mestdagh, P;
- Vandesompele, J;
- Speleman, F;
- Jastrow, H;
- Heukamp, L C;
- Schüle, R;
- Dührsen, U;
- Buettner, R;
- Eggert, A;
- Göthert, J R
Publication type:
Article
Elucidation of a novel pathogenomic mechanism using genome-wide long mate-pair sequencing of a congenital t(16;21) in a series of three RUNX1-mutated FPD/AML pedigrees.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2151, doi. 10.1038/leu.2012.79
By:
- Buijs, A;
- Poot, M;
- van der Crabben, S;
- van der Zwaag, B;
- van Binsbergen, E;
- van Roosmalen, M J;
- Tavakoli-Yaraki, M;
- de Weerdt, O;
- Nieuwenhuis, H K;
- van Gijn, M;
- Kloosterman, W P
Publication type:
Article
Expression of CD200 on AML blasts directly suppresses memory T-cell function.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2148, doi. 10.1038/leu.2012.77
By:
- Coles, S J;
- Hills, R K;
- Wang, E C Y;
- Burnett, A K;
- Man, S;
- Darley, R L;
- Tonks, A
Publication type:
Article
Design of novel BH3 mimetics for the treatment of chronic lymphocytic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2032, doi. 10.1038/leu.2012.88
By:
- Billard, C
Publication type:
Article
Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 1976, doi. 10.1038/leu.2012.125
By:
- Dekking, E H A;
- van der Velden, V H J;
- Varro, R;
- Wai, H;
- Böttcher, S;
- Kneba, M;
- Sonneveld, E;
- Koning, A;
- Boeckx, N;
- Van Poecke, N;
- Lucio, P;
- Mendonça, A;
- Sedek, L;
- Szczepański, T;
- Kalina, T;
- Kanderová, V;
- Hoogeveen, P;
- Flores-Montero, J;
- Chillón, M C;
- Orfao, A
Publication type:
Article
EuroFlow: Resetting leukemia and lymphoma immunophenotyping. Basis for companion diagnostics and personalized medicine.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 1899, doi. 10.1038/leu.2012.121
By:
- van Dongen, J J M;
- Orfao, A
Publication type:
Article
Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML).
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2096, doi. 10.1038/leu.2012.85
By:
- Hanfstein, B;
- Müller, M C;
- Hehlmann, R;
- Erben, P;
- Lauseker, M;
- Fabarius, A;
- Schnittger, S;
- Haferlach, C;
- Göhring, G;
- Proetel, U;
- Kolb, H-J;
- Krause, S W;
- Hofmann, W-K;
- Schubert, J;
- Einsele, H;
- Dengler, J;
- Hänel, M;
- Falge, C;
- Kanz, L;
- Neubauer, A
Publication type:
Article
Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3<sup>+</sup> regulatory T cells.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2146, doi. 10.1038/leu.2012.75
By:
- Coles, S J;
- Hills, R K;
- Wang, E C Y;
- Burnett, A K;
- Man, S;
- Darley, R L;
- Tonks, A
Publication type:
Article
Real-time PCR quantification of major Wilms' tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2086, doi. 10.1038/leu.2012.76
By:
- Kramarzova, K;
- Stuchly, J;
- Willasch, A;
- Gruhn, B;
- Schwarz, J;
- Cermak, J;
- Machova-Polakova, K;
- Fuchs, O;
- Stary, J;
- Trka, J;
- Boublikova, L
Publication type:
Article
Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2069, doi. 10.1038/leu.2012.116
By:
- Blackburn, J S;
- Liu, S;
- Raiser, D M;
- Martinez, S A;
- Feng, H;
- Meeker, N D;
- Gentry, J;
- Neuberg, D;
- Look, A T;
- Ramaswamy, S;
- Bernards, A;
- Trede, N S;
- Langenau, D M
Publication type:
Article
Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2144, doi. 10.1038/leu.2012.74
By:
- Bains, T;
- Heinrich, M C;
- Loriaux, M M;
- Beadling, C;
- Nelson, D;
- Warrick, A;
- Neff, T L;
- Tyner, J W;
- Dunlap, J;
- Corless, C L;
- Fan, G
Publication type:
Article
Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program Study
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2103, doi. 10.1038/leu.2012.83
By:
- Visco, C;
- Li, Y;
- Xu-Monette, Z Y;
- Miranda, R N;
- Green, T M;
- Tzankov, A;
- Wen, W;
- Liu, W-m;
- Kahl, B S;
- d'Amore, E S G;
- Montes-Moreno, S;
- Dybkær, K;
- Chiu, A;
- Tam, W;
- Orazi, A;
- Zu, Y;
- Bhagat, G;
- Winter, J N;
- Wang, H-Y;
- O'Neill, S
Publication type:
Article
Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2061, doi. 10.1038/leu.2012.115
By:
- Stone, R M;
- Fischer, T;
- Paquette, R;
- Schiller, G;
- Schiffer, C A;
- Ehninger, G;
- Cortes, J;
- Kantarjian, H M;
- DeAngelo, D J;
- Huntsman-Labed, A;
- Dutreix, C;
- del Corral, A;
- Giles, F
Publication type:
Article
CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2135, doi. 10.1038/leu.2012.80
By:
- Hosen, N;
- Matsuoka, Y;
- Kishida, S;
- Nakata, J;
- Mizutani, Y;
- Hasegawa, K;
- Mugitani, A;
- Ichihara, H;
- Aoyama, Y;
- Nishida, S;
- Tsuboi, A;
- Fujiki, F;
- Tatsumi, N;
- Nakajima, H;
- Hino, M;
- Kimura, T;
- Yata, K;
- Abe, M;
- Oka, Y;
- Oji, Y
Publication type:
Article
EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 1908, doi. 10.1038/leu.2012.120
By:
- van Dongen, J J M;
- Lhermitte, L;
- Böttcher, S;
- Almeida, J;
- van der Velden, V H J;
- Flores-Montero, J;
- Rawstron, A;
- Asnafi, V;
- Lécrevisse, Q;
- Lucio, P;
- Mejstrikova, E;
- Szczepański, T;
- Kalina, T;
- de Tute, R;
- Brüggemann, M;
- Sedek, L;
- Cullen, M;
- Langerak, A W;
- Mendonça, A;
- Macintyre, E
Publication type:
Article
Specific small nucleolar RNA expression profiles in acute leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2052, doi. 10.1038/leu.2012.111
By:
- Valleron, W;
- Laprevotte, E;
- Gautier, E-F;
- Quelen, C;
- Demur, C;
- Delabesse, E;
- Agirre, X;
- Prósper, F;
- Kiss, T;
- Brousset, P
Publication type:
Article