Works matching IS 08876924 AND DT 2012 AND VI 26 AND IP 4

Results: 46

Activation of apoptosis signaling eliminates CD34+ progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors.

Published in:

2012

By:

Mak DH;
Wang RY;
Schober WD;
Konopleva M;
Cortes J;
Kantarjian H;
Andreeff M;
Carter BZ;
Mak, D H;
Wang, R-Y;
Schober, W D;
Konopleva, M;
Cortes, J;
Kantarjian, H;
Andreeff, M;
Carter, B Z

Publication type:

journal article

Bisphosphonates as antimyeloma drugs.

Published in:

2012

By:

Modi ND;
Lentzsch S;
Modi, N D;
Lentzsch, S

Publication type:

journal article

Downregulation of MEIS1 impairs long-term expansion of CD34+ NPM1-mutated acute myeloid leukemia cells.

Published in:

2012

By:

Woolthuis CM;
Han L;
Verkaik-Schakel RN;
van Gosliga D;
Kluin PM;
Vellenga E;
Schuringa JJ;
Huls G

Publication type:

Journal Article

Notch is an essential upstream regulator of NF-[kappa]B and is relevant for survival of Hodgkin and Reed-Sternberg cells.

Published in:

2012

By:

Schwarzer R;
Dörken B;
Jundt F

Publication type:

Journal Article

Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 824, doi. 10.1038/leu.2011.280

By:

Georgiou, G;
Efthymiou, A;
Vardounioti, I;
Boutsikas, G;
Angelopoulou, M K;
Vassilakopoulos, T P;
Kyrtsonis, M-C;
Plata, E;
Tofas, P;
Bitsani, A;
Bartzi, V;
Pessach, I;
Dimou, M;
Panayiotidis, P

Publication type:

Article

Frequency of leukemic initiating cells does not depend on the xenotransplantation model used.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 858, doi. 10.1038/leu.2011.250

By:

Vargaftig, J;
Taussig, D C;
Griessinger, E;
Anjos-Afonso, F;
Lister, T A;
Cavenagh, J;
Oakervee, H;
Gribben, J;
Bonnet, D

Publication type:

Article

An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-α and cAMP/PKA pathways.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 769, doi. 10.1038/leu.2011.273

By:

Lv, M;
Zhang, X;
Jia, H;
Li, D;
Zhang, B;
Zhang, H;
Hong, M;
Jiang, T;
Jiang, Q;
Lu, J;
Huang, X;
Huang, B

Publication type:

Article

Involvement of the Syk-mTOR pathway in follicular lymphoma cell invasion and angiogenesis.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 795, doi. 10.1038/leu.2011.248

By:

Fruchon, S;
Kheirallah, S;
Al Saati, T;
Ysebaert, L;
Laurent, C;
Leseux, L;
Fournié, J J;
Laurent, G;
Bezombes, C

Publication type:

Article

Activation of apoptosis signaling eliminates CD34<sup>+</sup> progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 788, doi. 10.1038/leu.2011.285

By:

Mak, D H;
Wang, R-Y;
Schober, W D;
Konopleva, M;
Cortes, J;
Kantarjian, H;
Andreeff, M;
Carter, B Z

Publication type:

Article

High concordance of subtypes of childhood acute lymphoblastic leukemia within families: lessons from sibships with multiple cases of leukemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 675, doi. 10.1038/leu.2011.274

By:

Schmiegelow, K;
Lausten Thomsen, U;
Baruchel, A;
Pacheco, C E;
Pieters, Rob;
Pombo-de-Oliveira, M S;
Andersen, E W;
Rostgaard, K;
Hjalgrim, H;
Pui, C-H

Publication type:

Article

Phase 1b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 841, doi. 10.1038/leu.2011.286

By:

Kofler, D M;
Gawlik, B B;
Elter, T;
Gianella-Borradori, A;
Wendtner, C-M;
Hallek, M

Publication type:

Article

Interest of the association azacitidine-lenalidomide as frontline therapy in high-risk myelodysplasia or acute myeloid leukemia with complex karyotype.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 822, doi. 10.1038/leu.2011.284

By:

Scherman, E;
Malak, S;
Perot, C;
Gorin, N C;
Rubio, M T;
Isnard, F

Publication type:

Article

IPSS-independent prognostic value of plasma CXCL10, IL-7 and IL-6 levels in myelodysplastic syndromes.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 693, doi. 10.1038/leu.2011.251

By:

Pardanani, A;
Finke, C;
Lasho, T L;
Al-Kali, A;
Begna, K H;
Hanson, C A;
Tefferi, A

Publication type:

Article

Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 708, doi. 10.1038/leu.2011.255

By:

Deshpande, A;
Reddy, M M;
Schade, G O M;
Ray, A;
Chowdary, T K;
Griffin, J D;
Sattler, M

Publication type:

Article

Long-term transfusion independence in del(5q) MDS patients who discontinue lenalidomide.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 855, doi. 10.1038/leu.2011.268

By:

Giagounidis, A A N;
Kulasekararaj, A;
Germing, U;
Radkowski, R;
Haase, S;
Petersen, P;
Göhring, G;
Büsche, G;
Aul, C;
Mufti, G J;
Platzbecker, U

Publication type:

Article

Clinical laboratory markers of inflammation as determinants of chronic graft-versus-host disease activity and NIH global severity.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 633, doi. 10.1038/leu.2011.254

By:

Grkovic, L;
Baird, K;
Steinberg, S M;
Williams, K M;
Pulanic, D;
Cowen, E W;
Mitchell, S A;
Hakim, F T;
Martires, K J;
Avila, D N;
Taylor, T N;
Salit, R B;
Rowley, S D;
Zhang, D;
Fowler, D H;
Bishop, M R;
Gress, R E;
Pavletic, S Z

Publication type:

Article

Deletion of the tumor-suppressor gene NF1 occurs in 5% of myeloid malignancies and is accompanied by a mutation in the remaining allele in half of the cases.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 834, doi. 10.1038/leu.2011.296

By:

Haferlach, C;
Grossmann, V;
Kohlmann, A;
Schindela, S;
Kern, W;
Schnittger, S;
Haferlach, T

Publication type:

Article

Fusion proteins between ligands for NKG2D and CD20-directed single-chain variable fragments sensitize lymphoma cells for natural killer cell-mediated lysis and enhance antibody-dependent cellular cytotoxicity.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 830, doi. 10.1038/leu.2011.288

By:

Kellner, C;
Hallack, D;
Glorius, P;
Staudinger, M;
Mohseni Nodehi, S;
de Weers, M;
van de Winkel, J G J;
Parren, P W H I;
Stauch, M;
Valerius, T;
Repp, R;
Humpe, A;
Gramatzki, M;
Peipp, M

Publication type:

Article

Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 654, doi. 10.1038/leu.2011.267

By:

Creutzig, U;
Zimmermann, M;
Bourquin, J-P;
Dworzak, M N;
Kremens, B;
Lehrnbecher, T;
von Neuhoff, C;
Sander, A;
von Stackelberg, A;
Schmid, I;
Starý, J;
Steinbach, D;
Vormoor, J;
Reinhardt, D

Publication type:

Article

Management of treatment-emergent peripheral neuropathy in multiple myeloma.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 595, doi. 10.1038/leu.2011.346

By:

Richardson, P G;
Delforge, M;
Beksac, M;
Wen, P;
Jongen, J L;
Sezer, O;
Terpos, E;
Munshi, N;
Palumbo, A;
Rajkumar, S V;
Harousseau, J L;
Moreau, P;
Avet-Loiseau, H;
Lee, J H;
Cavo, M;
Merlini, G;
Voorhees, P;
Chng, W J;
Mazumder, A;
Usmani, S

Publication type:

Article

The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 736, doi. 10.1038/leu.2011.252

By:

Wu, W;
Kim, C H;
Liu, R;
Kucia, M;
Marlicz, W;
Greco, N;
Ratajczak, J;
Laughlin, M J;
Ratajczak, M Z

Publication type:

Article

Centrosomal targeting of tyrosine kinase activity does not enhance oncogenicity in chronic myeloproliferative disorders.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 728, doi. 10.1038/leu.2011.283

By:

Bochtler, T;
Kirsch, M;
Maier, B;
Bachmann, J;
Klingmüller, U;
Anderhub, S;
Ho, A D;
Krämer, A

Publication type:

Article

Effect of nucleophosmin1 haploinsufficiency on hematopoietic stem cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 853, doi. 10.1038/leu.2011.270

By:

Raval, A;
Kusler, B;
Pang, W W;
Weissman, I L;
Mitchell, B S;
Park, C Y

Publication type:

Article

Disparities in the prevalence, pathogenesis and progression of monoclonal gammopathy of undetermined significance and multiple myeloma between blacks and whites.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 609, doi. 10.1038/leu.2011.368

By:

Greenberg, A J;
Vachon, C M;
Rajkumar, S V

Publication type:

Article

EXEL-8232, a small-molecule JAK2 inhibitor, effectively treats thrombocytosis and extramedullary hematopoiesis in a murine model of myeloproliferative neoplasm induced by MPLW515L.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 720, doi. 10.1038/leu.2011.261

By:

Wernig, G;
Kharas, M G;
Mullally, A;
Leeman, D S;
Okabe, R;
George, T;
Clary, D O;
Gilliland, D G

Publication type:

Article

Venous thromboembolism in patients with essential thrombocythemia and polycythemia vera.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 563, doi. 10.1038/leu.2011.314

By:

Reikvam, H;
Tiu, R V

Publication type:

Article

Polymorphism of the erythropoietin gene promotor and the development of myelodysplastic syndromes subsequent to multiple myeloma.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 844, doi. 10.1038/leu.2011.262

By:

Landgren, O;
Ma, W;
Kyle, R A;
Rajkumar, S V;
Korde, N;
Albitar, M

Publication type:

Article

Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 623, doi. 10.1038/leu.2011.249

By:

Tyner, J W;
Jemal, A M;
Thayer, M;
Druker, B J;
Chang, B H

Publication type:

Article

MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 778, doi. 10.1038/leu.2011.287

By:

Konopleva, M;
Milella, M;
Ruvolo, P;
Watts, J C;
Ricciardi, M R;
Korchin, B;
McQueen, T;
Bornmann, W;
Tsao, T;
Bergamo, P;
Mak, D H;
Chen, W;
McCubrey, J;
Tafuri, A;
Andreeff, M

Publication type:

Article

NKL homeobox genes in leukemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 572, doi. 10.1038/leu.2011.330

By:

Homminga, I;
Pieters, R;
Meijerink, J P P

Publication type:

Article

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 644, doi. 10.1038/leu.2011.264

By:

Waldron, T;
De Dominici, M;
Soliera, A R;
Audia, A;
Iacobucci, I;
Lonetti, A;
Martinelli, G;
Zhang, Y;
Martinez, R;
Hyslop, T;
Bender, T P;
Calabretta, B

Publication type:

Article

Downregulation of MEIS1 impairs long-term expansion of CD34<sup>+</sup> NPM1-mutated acute myeloid leukemia cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 848, doi. 10.1038/leu.2011.277

By:

Woolthuis, C M;
Han, L;
Verkaik-Schakel, R N;
van Gosliga, D;
Kluin, P M;
Vellenga, E;
Schuringa, J J;
Huls, G

Publication type:

Article

Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 845, doi. 10.1038/leu.2011.259

By:

van der Weide, K;
Korthuis, P M;
Kuipers, F;
de Vries, E G E;
Vellenga, E

Publication type:

Article

Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 806, doi. 10.1038/leu.2011.265

By:

Schwarzer, R;
Dörken, B;
Jundt, F

Publication type:

Article

Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 682, doi. 10.1038/leu.2011.278

By:

Stumpel, D J P M;
Schneider, P;
Seslija, L;
Osaki, H;
Williams, O;
Pieters, R;
Stam, R W

Publication type:

Article

Inhibition of Myb-dependent gene expression by the sesquiterpene lactone mexicanin-I.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 615, doi. 10.1038/leu.2011.275

By:

Bujnicki, T;
Wilczek, C;
Schomburg, C;
Feldmann, F;
Schlenke, P;
Müller-Tidow, C;
Schmidt, T J;
Klempnauer, K-H

Publication type:

Article

Response to salvage therapies and outcome in patients with multiple myeloma relapsing after pomalidomide therapy.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 839, doi. 10.1038/leu.2011.279

By:

Sinha, S;
Lacy, M;
Mikhael, J;
Hayman, S;
Buadi, F;
Detweiler-Short, K;
Dispenzieri, A;
Gertz, M;
Dingli, D;
Rajkumar, S V;
Kumar, S K

Publication type:

Article

Bisphosphonates as antimyeloma drugs.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 589, doi. 10.1038/leu.2011.282

By:

Modi, N D;
Lentzsch, S

Publication type:

Article

Significantly worse survival of patients with NIH-defined chronic graft-versus-host disease and thrombocytopenia or progressive onset type: results of a prospective study.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 746, doi. 10.1038/leu.2011.257

By:

Kuzmina, Z;
Eder, S;
Böhm, A;
Pernicka, E;
Vormittag, L;
Kalhs, P;
Petkov, V;
Stary, G;
Nepp, J;
Knobler, R;
Just, U;
Krenn, K;
Worel, N;
Greinix, H T

Publication type:

Article

Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 826, doi. 10.1038/leu.2011.281

By:

Britt-Compton, B;
Lin, T T;
Ahmed, G;
Weston, V;
Jones, R E;
Fegan, C;
Oscier, D G;
Stankovic, T;
Pepper, C;
Baird, D M

Publication type:

Article

Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 716, doi. 10.1038/leu.2011.258

By:

Finazzi, G;
Carobbio, A;
Thiele, J;
Passamonti, F;
Rumi, E;
Ruggeri, M;
Rodeghiero, F;
Randi, M L;
Bertozzi, I;
Vannucchi, A M;
Antonioli, E;
Gisslinger, H;
Buxhofer-Ausch, V;
Gangat, N;
Rambaldi, A;
Tefferi, A;
Barbui, T

Publication type:

Article

Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 582, doi. 10.1038/leu.2011.349

By:

Kumar, A;
Mhaskar, A R;
Reljic, T;
Mhaskar, R S;
Kharfan-Dabaja, M A;
Anasetti, C;
Mohty, M;
Djulbegovic, B

Publication type:

Article

Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 662, doi. 10.1038/leu.2011.271

By:

Chaib, H;
Nebbioso, A;
Prebet, T;
Castellano, R;
Garbit, S;
Restouin, A;
Vey, N;
Altucci, L;
Collette, Y

Publication type:

Article

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 757, doi. 10.1038/leu.2011.256

By:

Franke, N E;
Niewerth, D;
Assaraf, Y G;
van Meerloo, J;
Vojtekova, K;
van Zantwijk, C H;
Zweegman, S;
Chan, E T;
Kirk, C J;
Geerke, D P;
Schimmer, A D;
Kaspers, G J L;
Jansen, G;
Cloos, J

Publication type:

Article

Immunoglobulin gene repertoire in ocular adnexal lymphomas: hints on the nature of the antigenic stimulation.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 814, doi. 10.1038/leu.2011.276

By:

Dagklis, A;
Ponzoni, M;
Govi, S;
Cangi, M G;
Pasini, E;
Charlotte, F;
Vino, A;
Doglioni, C;
Davì, F;
Lossos, I S;
Ntountas, I;
Papadaki, T;
Dolcetti, R;
Ferreri, A J M;
Stamatopoulos, K;
Ghia, P

Publication type:

Article

Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 700, doi. 10.1038/leu.2011.272

By:

Calado, R T;
Cooper, J N;
Padilla-Nash, H M;
Sloand, E M;
Wu, C O;
Scheinberg, P;
Ried, T;
Young, N S

Publication type:

Article