Works matching IS 08876924 AND DT 2011 AND VI 25 AND IP 5

Results: 23

Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model.

Published in:

2011

By:

Tamai, H.;
Miyake, K.;
Takatori, M.;
Miyake, N.;
Yamaguchi, H.;
Dan, K.;
Shimada, T.;
Inokuchi, K.

Publication type:

Letter

Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 781, doi. 10.1038/leu.2011.20

By:

Evangelisti, C.;
Ricci, F.;
Tazzari, P.;
Tabellini, G.;
Battistelli, M.;
Falcieri, E.;
Chiarini, F.;
Bortul, R.;
Melchionda, F.;
Pagliaro, P.;
Pession, A.;
McCubrey, J. A.;
Martelli, A. M.

Publication type:

Article

The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.

Published in:

2011

By:

Haferlach, C.;
Bacher, U.;
Haferlach, T.;
Dicker, F.;
Alpermann, T.;
Kern, W.;
Schnittger, S.

Publication type:

Letter

Reply to: 'Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity' by Kern et al.

Published in:

2011

By:

Oelschlaegel, U.;
Mohr, B.;
Schaich, M.;
Kroschinsky, F.;
Parmentier, S.;
Bornhäuser, M.;
Ehninger, G.;
Thiede, C.

Publication type:

Letter

Optimizing the use of lenalidomide in relapsed or refractory multiple myeloma: consensus statement.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 749, doi. 10.1038/leu.2011.3

By:

Dimopoulos, M. A.;
Palumbo, A.;
Attal, M.;
Beksaç, M.;
Davies, F. E.;
Delforge, M.;
Einsele, H.;
Hajek, R.;
Harousseau, J.-L.;
da Costa, F. Leal;
Ludwig, H.;
Mellqvist, U.-H.;
Morgan, G. J.;
San-Miguel, J. F.;
Zweegman, S.;
Sonneveld, P.

Publication type:

Article

Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 808, doi. 10.1038/leu.2011.13

By:

Craddock, C.;
Labopin, M.;
Pillai, S.;
Finke, J.;
Bunjes, D.;
Greinix, H.;
Ehninger, G.;
Steckel, N.-K.;
Zander, A. R.;
Schwerdtfeger, R.;
Buchholz, S.;
Kolb, H.-J.;
Volin, L.;
Fauser, A.;
Polge, E.;
Schmid, C.;
Mohty, M.;
Rocha, V.

Publication type:

Article

Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.

Published in:

2011

By:

Grossmann, V.;
Kohlmann, A.;
Eder, C.;
Haferlach, C.;
Kern, W.;
Cross, N. C. P.;
Haferlach, T.;
Schnittger, S.

Publication type:

Letter

Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 838, doi. 10.1038/leu.2011.2

By:

Huber, S.;
Oelsner, M.;
Decker, T.;
zum Büschenfelde, C. Meyer;
Wagner, M.;
Lutzny, G.;
Kuhnt, T.;
Schmidt, B.;
Oostendorp, R. A. J.;
Peschel, C.;
Ringshausen, I.

Publication type:

Article

Phase I study of the anti insulin-like growth factor 1 receptor (IGF-1R) monoclonal antibody, AVE1642, as single agent and in combination with bortezomib in patients with relapsed multiple myeloma.

Published in:

2011

By:

Moreau, P.;
Cavallo, F.;
Leleu, X.;
Hulin, C.;
Amiot, M.;
Descamps, G.;
Facon, T.;
Boccadoro, M.;
Mignard, D.;
Harousseau, J. L.

Publication type:

Letter

In vitro-established alloantigen-specific CD8<sup>+</sup> CTLs mediate graft-versus-tumor activity in the absence of graft-versus-host disease.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 848, doi. 10.1038/leu.2011.16

By:

Hartmann, N.;
Leithäuser, F.;
Albers, C.;
Duyster, J.;
Möller, P.;
Debatin, K.-M.;
Strauss, G.

Publication type:

Article

Relative fitness of hematopoietic progenitors influences leukemia progression.

Published in:

2011

By:

Porter, C. C.;
Baturin, D.;
Choudhary, R.;
DeGregori, J.

Publication type:

Letter

p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells.

Published in:

2011

By:

Peterson, L. F.;
Mitrikeska, E.;
Giannola, D.;
Lui, Y.;
Sun, H.;
Bixby, D.;
Malek, S. N.;
Donato, N. J.;
Wang, S.;
Talpaz, M.

Publication type:

journal article

Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 821, doi. 10.1038/leu.2011.19

By:

Greif, P. A.;
Eck, S. H.;
Konstandin, N. P.;
Benet-Pagès, A.;
Ksienzyk, B.;
Dufour, A.;
Vetter, A. T.;
Popp, H. D.;
Lorenz-Depiereux, B.;
Meitinger, T.;
Bohlander, S. K.;
Strom, T. M.

Publication type:

Article

Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).

Published in:

2011

By:

Drakos, E.;
Singh, R. R.;
Rassidakis, G. Z.;
Schlette, E.;
Li, J.;
Claret, F. X.;
Ford, Jr., R. J.;
Vega, F.;
Medeiros, L. J.;
Ford, R J Jr

Publication type:

journal article

Interferon-α in acute myeloid leukemia: an old drug revisited.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 739, doi. 10.1038/leu.2010.324

By:

Anguille, S.;
Lion, E.;
Willemen, Y.;
Van Tendeloo, V. F. I.;
Berneman, Z. N.;
Smits, E. L. J. M.

Publication type:

Article

HAX-1 expression in human B lymphoma.

Published in:

2011

By:

Kwiecinska, A.;
Ottosson-Wadlund, A.;
Ceder, R.;
Grafström, R. C.;
Björck, E.;
Nordenskjöld, M.;
Porwit, A.;
Fadeel, B.

Publication type:

Letter

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells.

Published in:

Leukemia (08876924), 2011, v. 25, n. 5, p. 828, doi. 10.1038/leu.2011.12

By:

Coscia, M.;
Pantaleoni, F.;
Riganti, C.;
Vitale, C.;
Rigoni, M.;
Peola, S.;
Castella, B.;
Foglietta, M.;
Griggio, V.;
Drandi, D.;
Ladetto, M.;
Bosia, A.;
Boccadoro, M.;
Massaia, M.

Publication type:

Article

CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia.

Published in:

2011

By:

Coles, S. J.;
Wang, E. C. Y.;
Man, S.;
Hills, R. K.;
Burnett, A. K.;
Tonks, A.;
Darley, R. L.

Publication type:

journal article

Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720.

Published in:

2011

By:

Baer, M. R.;
George, S. L.;
Sanford, B. L.;
Mrózek, K.;
Kolitz, J. E.;
Moore, J. O.;
Stone, R. M.;
Powell, B. L.;
Caligiuri, M. A.;
Bloomfield, C. D.;
Larson, R. A.;
Mrózek, K;
Cancer and Leukemia Group B

Publication type:

journal article

Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy.

Published in:

2011

By:

Tuve, S.;
Gayoso, J.;
Scheid, C.;
Radke, J.;
Kiani, A.;
Serrano, D.;
Platzbecker, U.;
Rodríguez-Macías, G.;
Wermke, M.;
Holtick, U.;
Balsalobre, P.;
Middeke, J. M.;
Shayegi, N.;
Chemnitz, J. M.;
Krause, A.;
Gruner, N.;
Füssel, M.;
Schetelig, J.;
Thiede, C.;
Ehninger, G.

Publication type:

Letter

Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.

Published in:

2011

By:

Vandewoestyne, M. L.;
Pede, V. C.;
Lambein, K. Y.;
Dhaenens, M. F.;
Offner, F. C.;
Praet, M. M.;
Philippé, J. J.;
Kipps, T. J.;
Deforce, D. L.

Publication type:

Letter

The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha.

Published in:

2011

By:

Occhionorelli, M.;
Santoro, F.;
Pallavicini, I.;
Gruszka, A.;
Moretti, S.;
Bossi, D.;
Viale, A.;
Shing, D.;
Ronzoni, S.;
Muradore, I.;
Soncini, M.;
Pruneri, G.;
Rafaniello, P.;
Viale, G.;
Pelicci, P. G.;
Minucci, S.

Publication type:

journal article

Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.

Published in:

2011

By:

Gandillet, A.;
Park, S.;
Lassailly, F.;
Griessinger, E.;
Vargaftig, J.;
Filby, A.;
Lister, T. A.;
Bonnet, D.;
Gandillet, Arnaud;
Park, Sophie;
Lassailly, François;
Griessinger, Emmanuel;
Vargaftig, Jacques;
Filby, Andrew;
Lister, T Andrew;
Bonnet, Dominique

Publication type:

journal article