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Results: 36

Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: long-term follow-up.
Published in:
2010
By:
- Shimoni, A.;
- Hardan, I.;
- Shem-Tov, N.;
- Yerushalmi, R.;
- Nagler, A.
Publication type:
Letter
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
Published in:
2010
By:
- Jenal, M.;
- Batliner, J.;
- Reddy, V. A.;
- Haferlach, T.;
- Tobler, A.;
- Fey, M. F.;
- Torbett, B. E.;
- Tschan, M. P.
Publication type:
Letter
KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia.
Published in:
2010
By:
- Medves, S.;
- Duhoux, F. P.;
- Ferrant, A.;
- Toffalini, F.;
- Ameye, G.;
- Libouton, J.-M.;
- Poirel, H. A.;
- Demoulin, J.-B.
Publication type:
Letter
Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype.
Published in:
2010
By:
- Hurton, L. V.;
- Siddik, R. I.;
- Singh, H.;
- Olivares, S.;
- Rabinovich, B. A.;
- Tian, R.;
- Mojsilovic, D.;
- Hildebrand, W.;
- Lee, D. A.;
- Kelly, S. S.;
- Champlin, R.;
- Shpall, E. J.;
- Fernandez-Viña, M.;
- Cooper, L. J. N.;
- Fernandez-Viña, M
Publication type:
Letter
Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.
Published in:
2010
By:
- Boultwood, J.;
- Perry, J.;
- Pellagatti, A.;
- Fernandez-Mercado, M.;
- Fernandez-Santamaria, C.;
- Calasanz, M. J.;
- Larrayoz, M. J.;
- Garcia-Delgado, M.;
- Giagounidis, A.;
- Malcovati, L.;
- Della Porta, M. G.;
- Jädersten, M.;
- Killick, S.;
- Hellström-Lindberg, E.;
- Cazzola, M.;
- Wainscoat, J. S.
Publication type:
Letter
AML with CBFB–MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1065, doi. 10.1038/leu.2010.22
By:
- Haferlach, C.;
- Dicker, F.;
- Kohlmann, A.;
- Schindela, S.;
- Weiss, T.;
- Kern, W.;
- Schnittger, S.;
- Haferlach, T.
Publication type:
Article
JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5.
Published in:
2010
By:
- Cleyrat, C.;
- Jelinek, J.;
- Girodon, F.;
- Boissinot, M.;
- Ponge, T.;
- Harousseau, J.-L.;
- Issa, J.-P.;
- Hermouet, S.
Publication type:
Letter
Human leukocyte antigen (HLA) A1-B8-DR3 (8.1) haplotype, tumor necrosis factor (TNF) G-308A, and risk of non-Hodgkin lymphoma.
Published in:
2010
By:
- Abdou, A. M.;
- Gao, X.;
- Cozen, W.;
- Cerhan, J. R.;
- Rothman, N.;
- Martin, M. P.;
- Davis, S.;
- Schenk, M.;
- Chanock, S. J.;
- Hartge, P.;
- Carrington, M.;
- Wang, S. S.
Publication type:
research
Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1012, doi. 10.1038/leu.2010.30
By:
- Chen, J.;
- Li, Y.;
- Doedens, M.;
- Wang, P.;
- Shago, M.;
- Dick, J.;
- Hitzler, J. K.
Publication type:
Article
Wilms’ tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 992, doi. 10.1038/leu.2010.33
By:
- Vidovic, K.;
- Svensson, E.;
- Nilsson, B.;
- Thuresson, B.;
- Olofsson, T.;
- Lennartsson, A.;
- Gullberg, U.
Publication type:
Article
Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 924, doi. 10.1038/leu.2010.39
By:
- Davidsson, J.;
- Paulsson, K.;
- Lindgren, D.;
- Lilljebjörn, H.;
- Chaplin, T.;
- Forestier, E.;
- Andersen, M. K.;
- Nordgren, A.;
- Rosenquist, R.;
- Fioretos, T.;
- Young, B. D.;
- Johansson, B.
Publication type:
Article
AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1018, doi. 10.1038/leu.2010.40
By:
- Komeno, Y;
- Kitaura, J;
- Watanabe-Okochi, N;
- Kato, N;
- Oki, T;
- Nakahara, F;
- Harada, Y;
- Harada, H;
- Shinkura, R;
- Nagaoka, H;
- Hayashi, Y;
- Honjo, T;
- Kitamura, T
Publication type:
Article
Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 932, doi. 10.1038/leu.2010.41
By:
- Deneberg, S.;
- Grövdal, M.;
- Karimi, M.;
- Jansson, M.;
- Nahi, H.;
- Corbacioglu, A.;
- Gaidzik, V.;
- Döhner, K.;
- Paul, C.;
- Ekström, T. J.;
- Hellström-Lindberg, E.;
- Lehmann, S.
Publication type:
Article
Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motif.
Published in:
2010
By:
- Yassin, E. R.;
- Abdul-Nabi, A. M.;
- Takeda, A.;
- Yaseen, N. R.
Publication type:
journal article
Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1025, doi. 10.1038/leu.2010.35
By:
- Singh, R. R.;
- Kim, J. E.;
- Davuluri, Y.;
- Drakos, E.;
- Cho-Vega, J. H.;
- Amin, H. M.;
- Vega, F.
Publication type:
Article
Relevant mouse model for human monocytic leukemia through Cre/lox-controlled myeloid-specific deletion of PTEN.
Published in:
2010
By:
- Yu, H.;
- Li, Y.;
- Gao, C.;
- Fabien, L.;
- Jia, Y.;
- Lu, J.;
- Silberstein, L. E.;
- Pinkus, G. S.;
- Ye, K.;
- Chai, L.;
- Luo, H. R.
Publication type:
Letter
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 958, doi. 10.1038/leu.2010.36
By:
- Vaisitti, T.;
- Aydin, S.;
- Rossi, D.;
- Cottino, F.;
- Bergui, L.;
- D'Arena, G.;
- Bonello, L.;
- Horenstein, A. L.;
- Brennan, P.;
- Pepper, C.;
- Gaidano, G.;
- Malavasi, F.;
- Deaglio, S.
Publication type:
Article
Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML.
Published in:
2010
By:
- Pulikkan, J. A.;
- Dengler, V.;
- Peer Zada, A. A.;
- Kawasaki, A.;
- Geletu, M.;
- Pasalic, Z.;
- Bohlander, S. K.;
- Ryo, A.;
- Tenen, D. G.;
- Behre, G.
Publication type:
journal article
Cytotoxic T cells transduced with chimeric anti-CD19 receptors prevent engraftment of primary lymphoblastic leukemia in vivo.
Published in:
2010
By:
- Landmeier, S.;
- Altvater, B.;
- Pscherer, S.;
- Meltzer, J.;
- Sebire, N.;
- Pule, M.;
- Vera, J.;
- Hotfilder, M.;
- Juergens, H.;
- Vormoor, J.;
- Rossig, C.
Publication type:
Letter
A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide.
Published in:
2010
By:
- Ji, Z.;
- Zhang, L.;
- Peng, V.;
- Ren, X.;
- McHale, C. M.;
- Smith, M. T.
Publication type:
journal article
Higher expression levels of activation-induced cytidine deaminase distinguish hairy cell leukemia from hairy cell leukemia-variant and splenic marginal zone lymphoma.
Published in:
2010
By:
- Hockley, S. L.;
- Morilla, A.;
- Else, M.;
- Dearden, C.;
- Catovsky, D.;
- Morgan, G. J.;
- Matutes, E.;
- Gonzalez, D.
Publication type:
Letter
Eltrombopag, a second-generation thrombopoietin receptor agonist, for chronic lymphocytic leukemia-associated ITP.
Published in:
2010
By:
- Koehrer, S.;
- Keating, M. J.;
- Wierda, W. G.
Publication type:
Case Study
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation.
Published in:
2010
By:
- Efanov, A.;
- Zanesi, N.;
- Nazaryan, N.;
- Santanam, U.;
- Palamarchuk, A.;
- Croce, C. M.;
- Pekarsky, Y.
Publication type:
journal article
EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 942, doi. 10.1038/leu.2010.47
By:
- Balgobind, B. V.;
- Lugthart, S.;
- Hollink, I. H.;
- Arentsen-Peters, S. T. J. C. M.;
- van Wering, E. R.;
- de Graaf, S. S. N.;
- Reinhardt, D.;
- Creutzig, U.;
- Kaspers, G. J. L.;
- de Bont, E. S. J. M.;
- Stary, J.;
- Trka, J.;
- Zimmermann, M.;
- Beverloo, H. B.;
- Pieters, R.;
- Delwel, R.;
- Zwaan, C. M.;
- van den Heuvel-Eibrink, M. M.
Publication type:
Article
MSK1 activation in acute myeloid leukemia cells with FLT3 mutations.
Published in:
2010
By:
- Odgerel, T.;
- Kikuchi, J.;
- Wada, T.;
- Shimizu, R.;
- Kano, Y.;
- Furukawa, Y.
Publication type:
Letter
CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome.
Published in:
2010
By:
- Shiba, N.;
- Kato, M.;
- Park, M.-j.;
- Sanada, M.;
- Ito, E.;
- Fukushima, K.;
- Sako, M.;
- Arakawa, H.;
- Ogawa, S.;
- Hayashi, Y.
Publication type:
Letter
Trisomy 11: prevalence among 22 403 unique patient cytogenetic studies and clinical correlates.
Published in:
2010
By:
- Caramazza, D.;
- Ketterling, R. P.;
- Knudson, R. A.;
- Hanson, C. A.;
- Siragusa, S.;
- Pardanani, A.;
- Tefferi, A.
Publication type:
Letter
Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms.
Published in:
2010
By:
- Kosmider, O.;
- Gelsi-Boyer, V.;
- Slama, L.;
- Dreyfus, F.;
- Beyne-Rauzy, O.;
- Quesnel, B.;
- Hunault-Berger, M.;
- Slama, B.;
- Vey, N.;
- Lacombe, C.;
- Solary, E.;
- Birnbaum, D.;
- Bernard, O. A.;
- Fontenay, M.
Publication type:
Letter
Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex.
Published in:
2010
By:
- Ratajczak, M. Z.;
- Lee, H.;
- Wysoczynski, M.;
- Wan, W.;
- Marlicz, W.;
- Laughlin, M. J.;
- Kucia, M.;
- Janowska-Wieczorek, A.;
- Ratajczak, J.
Publication type:
journal article
Targeting lysosomes to eradicate imatinib-resistant chronic myelogenous leukemia cells.
Published in:
2010
By:
- Puissant,3, A.;
- Dufies, M.;
- Raynaud, S.;
- Cassuto, J.-P.;
- Auberger, P.
Publication type:
Letter
Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.
Published in:
2010
By:
- Ho, P. A.;
- Alonzo, T. A.;
- Kopecky, K. J.;
- Miller, K. L.;
- Kuhn, J.;
- Zeng, R.;
- Gerbing, R. B.;
- Raimondi, S. C.;
- Hirsch, B. A.;
- Oehler, V.;
- Hurwitz, C. A.;
- Franklin, J. L.;
- Gamis, A. S.;
- Petersdorf, S. H.;
- Anderson, J. E.;
- Reaman, G. H.;
- Baker, L. H.;
- Willman, C. L.;
- Bernstein, I. D.;
- Radich, J. P.
Publication type:
journal article
Lenalidomide, melphalan, prednisone and thalidomide (RMPT) for relapsed/refractory multiple myeloma.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1037, doi. 10.1038/leu.2010.58
By:
- Palumbo, A.;
- Larocca, A.;
- Falco, P.;
- Sanpaolo, G.;
- Falcone, A. P.;
- Federico, V.;
- Canepa, L.;
- Crugnola, M.;
- Genuardi, M.;
- Magarotto, V.;
- Petrucci, M. T;
- Boccadoro, M.
Publication type:
Article
POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature.
Published in:
2010
By:
- Fortier, J. M.;
- Payton, J. E.;
- Cahan, P.;
- Ley, T. J.;
- Walter, M. J.;
- Graubert, T. A.
Publication type:
journal article
Prognostic variables for survival and skeletal complications in patients with multiple myeloma osteolytic bone disease.
Published in:
Leukemia (08876924), 2010, v. 24, n. 5, p. 1043, doi. 10.1038/leu.2010.62
By:
- Terpos, E.;
- Berenson, J.;
- Cook, R. J.;
- Lipton, A.;
- Coleman, R. E.
Publication type:
Article
Retraction. Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between the NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations.
Published in:
2010
By:
- Cilloni, D;
- Messa, F;
- Rosso, V;
- Arruga, F;
- Defilippi, I;
- Carturan, S;
- Catalano, R;
- Pautasso, M;
- Panuzzo, C;
- Nicoli, P;
- Messa, E;
- Morotti, A;
- Iacobucci, I;
- Martinelli, G;
- Bracco, E;
- Saglio, G
Publication type:
corrected article
Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia.
Published in:
2010
By:
- Hochhaus, A;
- O'Brien, S G;
- Guilhot, F;
- Druker, B J;
- Branford, S;
- Foroni, L;
- Goldman, J M;
- Müller, M C;
- Radich, J P;
- Rudoltz, M;
- Mone, M;
- Gathmann, I;
- Hughes, T P;
- Larson, R A
Publication type:
Correction Notice