Works matching IS 08876924 AND DT 2010 AND VI 24 AND IP 10

Results: 25

The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma.

Published in:

2010

By:

Bhende, P. M.;
Park, S. I.;
Lim, M. S.;
Dittmer, D. P.;
Damania, B.

Publication type:

Letter

The use of biochemical markers of bone remodeling in multiple myeloma: a report of the International Myeloma Working Group.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1700, doi. 10.1038/leu.2010.173

By:

Terpos, E.;
Dimopoulos, M. A.;
Sezer, O.;
Roodman, D.;
Abildgaard, N.;
Vescio, R.;
Tosi, P.;
Garcia-Sanz, R.;
Davies, F.;
Chanan-Khan, A.;
Palumbo, A.;
Sonneveld, P.;
Drake, M. T.;
Harousseau, J.-L.;
Anderson, K. C.;
Durie, B. G. M.

Publication type:

Article

HH-GV-678, a novel selective inhibitor of Bcr-Abl, outperforms imatinib and effectively overrides imatinib resistance.

Published in:

2010

By:

Luo, H.;
Quan, H.;
Xie, C.;
Xu, Y.;
Fu, L.;
Lou, L.

Publication type:

Letter

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies.

Published in:

2010

By:

Makishima, H.;
Jankowska, A. M.;
Tiu, R. V.;
Szpurka, H.;
Sugimoto, Y.;
Hu, Z.;
Saunthararajah, Y.;
Guinta, K.;
Keddache, M. A.;
Putnam, P.;
Sekeres, M. A.;
Moliterno, A. R.;
List, A. F.;
McDevitt, M. A.;
Maciejewski, J. P.

Publication type:

Letter

Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation.

Published in:

2010

By:

Jaganathan, B. G.;
Tisato, V.;
Vulliamy, T.;
Dokal, I.;
Marsh, J.;
Dazzi, F.;
Bonnet, D.

Publication type:

Case Study

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis.

Published in:

2010

By:

Gan, T.;
Jude, C. D.;
Zaffuto, K.;
Ernst, P.

Publication type:

journal article

The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1725, doi. 10.1038/leu.2010.165

By:

Michallet, M.;
Sobh, M.;
Milligan, D.;
Morisset, S.;
Niederwieser, D.;
Koza, V.;
Ruutu, T.;
Russell, N. H.;
Verdonck, L.;
Dhedin, N.;
Vitek, A.;
Boogaerts, M.;
Vindelov, L.;
Finke, J.;
Dubois, V.;
van Biezen, A.;
Brand, R.;
de Witte, T.;
Dreger, P.

Publication type:

Article

Analysis of BCR-ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype.

Published in:

2010

By:

Grant, H.;
Jiang, X.;
Stebbing, J.;
Foroni, L.;
Craddock, C.;
Griffiths, M.;
Clark, R. E.;
O'Brien, S.;
Khorashad, J. S.;
Gerrard, G.;
Wang, L.;
Irving, J. A. E.;
Wang, M.;
Karran, L.;
Dyer, M. J. S.;
Forrest, D.;
Page, K.;
Eaves, C. J.;
Woolfson, A.

Publication type:

research

Innate immunity as orchestrator of stem cell mobilization.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1667, doi. 10.1038/leu.2010.162

By:

Ratajczak, M. Z.;
Kim, C. H.;
Wojakowski, W.;
Janowska-Wieczorek, A.;
Kucia, M.;
Ratajczak, J.

Publication type:

Article

Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1719, doi. 10.1038/leu.2010.185

By:

Ross, D. M.;
Branford, S.;
Seymour, J. F.;
Schwarer, A. P.;
Arthur, C.;
Bartley, P. A.;
Slader, C.;
Field, C.;
Dang, P.;
Filshie, R. J.;
Mills, A. K.;
Grigg, A. P.;
Melo, J. V.;
Hughes, T. P.

Publication type:

Article

Spotlight series on stem cell mobilization: many hands on the ball, but who is the quarterback?

Published in:

2010

By:

Ratajczak, M. Z.

Publication type:

Editorial

Robust in vivo differentiation of t(8;21)-positive acute myeloid leukemia blasts to neutrophilic granulocytes induced by treatment with dasatinib.

Published in:

2010

By:

Chevalier, N.;
Solari, M. L.;
Becker, H.;
Pantic, M.;
Gärtner, F.;
Maul-Pavicic, A.;
Hübner, J.;
Wäsch, R.;
Schmitt-Gräff, A.;
Lübbert, M.

Publication type:

Letter

Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia.

Published in:

2010

By:

Oelschlaegel, U.;
Koch, S.;
Mohr, B.;
Schaich, M.;
Falini, B.;
Ehninger, G.;
Thiede, C.

Publication type:

Letter

Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.

Published in:

2010

By:

Davenport, E. L.;
Zeisig, A.;
Aronson, L. I.;
Moore, H. E.;
Hockley, S.;
Gonzalez, D.;
Smith, E. M.;
Powers, M. V.;
Sharp, S. Y.;
Workman, P.;
Morgan, G. J.;
Davies, F. E.

Publication type:

Letter

Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1686, doi. 10.1038/leu.2010.170

By:

Chapuis, N.;
Tamburini, J.;
Green, A. S.;
Willems, L.;
Bardet, V.;
Park, S.;
Lacombe, C.;
Mayeux, P.;
Bouscary, D.

Publication type:

Article

HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1760, doi. 10.1038/leu.2010.157

By:

Shimizu, R.;
Kikuchi, J.;
Wada, T.;
Ozawa, K.;
Kano, Y.;
Furukawa, Y.

Publication type:

Article

Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia.

Published in:

2010

By:

Bulgar, A. D.;
Snell, M.;
Donze, J. R.;
Kirkland, E. B.;
Li, L.;
Yang, S.;
Xu, Y.;
Gerson, S. L.;
Liu, L.

Publication type:

Letter

Meis1 disrupts the genomic imprint of Dlk1 in a NUP98-HOXD13 leukemia model.

Published in:

2010

By:

Argiropoulos, B.;
Palmqvist, L.;
Imren, S.;
Miller, M.;
Rouhi, A.;
Mager, D. L.;
Humphries, R. K.

Publication type:

Letter

Treatment of patients with relapsed/refractory multiple myeloma with lenalidomide and dexamethasone with or without bortezomib: prospective evaluation of the impact of cytogenetic abnormalities and of previous therapies.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1769, doi. 10.1038/leu.2010.175

By:

Dimopoulos, M. A.;
Kastritis, E.;
Christoulas, D.;
Migkou, M.;
Gavriatopoulou, M.;
Gkotzamanidou, M.;
Iakovaki, M.;
Matsouka, C.;
Mparmparoussi, D.;
Roussou, M.;
Efstathiou, E.;
Terpos, E.

Publication type:

Article

JAK2 46/1 haplotype analysis in myeloproliferative neoplasms and acute myeloid leukemia.

Published in:

2010

By:

Andrikovics, H.;
Nahajevszky, S.;
Koszarska, M.;
Meggyesi, N.;
Bors, A.;
Halm, G.;
Lueff, S.;
Lovas, N.;
Matrai, Z.;
Csomor, J.;
Rasonyi, R.;
Egyed, M.;
Varkonyi, J.;
Mikala, G.;
Sipos, A.;
Kozma, A.;
Adam, E.;
Fekete, S.;
Masszi, T.;
Tordai, A.

Publication type:

Letter

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.

Published in:

2010

By:

Wunderlich, M.;
Chou, F.-S.;
Link, K. A.;
Mizukawa, B.;
Perry, R. L.;
Carroll, M.;
Mulloy, J. C.

Publication type:

Letter

Genomic profiling of high-risk acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1676, doi. 10.1038/leu.2010.177

By:

Collins-Underwood, J. R.;
Mullighan, C. G.

Publication type:

Article

LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations.

Published in:

2010

By:

Pardanani, A.;
Lasho, T.;
Finke, C.;
Oh, S. T.;
Gotlib, J.;
Tefferi, A.

Publication type:

journal article

Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.

Published in:

Leukemia (08876924), 2010, v. 24, n. 10, p. 1751, doi. 10.1038/leu.2010.155

By:

Gessner, A.;
Thomas, M.;
Garrido Castro, P.;
Büchler, L.;
Scholz, A.;
Brümmendorf, T. H.;
Martinez Soria, N.;
Vormoor, J.;
Greil, J.;
Heidenreich, O.

Publication type:

Article

Analysis of genomic breakpoints in p190 and p210 BCR-ABL indicate distinct mechanisms of formation.

Published in:

2010

By:

Score, J.;
Calasanz, M. J.;
Ottman, O.;
Pane, F.;
Yeh, R. F.;
Sobrinho-Simões, M. A.;
Kreil, S.;
Ward, D.;
Hidalgo-Curtis, C.;
Melo, J. V.;
Wiemels, J.;
Nadel, B.;
Cross, N. C. P.;
Grand, F. H.;
Sobrinho-Simões, M A

Publication type:

journal article