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Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 781, doi. 10.1038/leu.2011.20
By:
- Evangelisti, C.;
- Ricci, F.;
- Tazzari, P.;
- Tabellini, G.;
- Battistelli, M.;
- Falcieri, E.;
- Chiarini, F.;
- Bortul, R.;
- Melchionda, F.;
- Pagliaro, P.;
- Pession, A.;
- McCubrey, J. A.;
- Martelli, A. M.
Publication type:
Article
The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.
Published in:
2011
By:
- Haferlach, C.;
- Bacher, U.;
- Haferlach, T.;
- Dicker, F.;
- Alpermann, T.;
- Kern, W.;
- Schnittger, S.
Publication type:
Letter
Reply to: 'Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity' by Kern et al.
Published in:
2011
By:
- Oelschlaegel, U.;
- Mohr, B.;
- Schaich, M.;
- Kroschinsky, F.;
- Parmentier, S.;
- Bornhäuser, M.;
- Ehninger, G.;
- Thiede, C.
Publication type:
Letter
IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 828, doi. 10.1038/leu.2011.12
By:
- Coscia, M.;
- Pantaleoni, F.;
- Riganti, C.;
- Vitale, C.;
- Rigoni, M.;
- Peola, S.;
- Castella, B.;
- Foglietta, M.;
- Griggio, V.;
- Drandi, D.;
- Ladetto, M.;
- Bosia, A.;
- Boccadoro, M.;
- Massaia, M.
Publication type:
Article
Optimizing the use of lenalidomide in relapsed or refractory multiple myeloma: consensus statement.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 749, doi. 10.1038/leu.2011.3
By:
- Dimopoulos, M. A.;
- Palumbo, A.;
- Attal, M.;
- Beksaç, M.;
- Davies, F. E.;
- Delforge, M.;
- Einsele, H.;
- Hajek, R.;
- Harousseau, J.-L.;
- da Costa, F. Leal;
- Ludwig, H.;
- Mellqvist, U.-H.;
- Morgan, G. J.;
- San-Miguel, J. F.;
- Zweegman, S.;
- Sonneveld, P.
Publication type:
Article
Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.
Published in:
2011
By:
- Grossmann, V.;
- Kohlmann, A.;
- Eder, C.;
- Haferlach, C.;
- Kern, W.;
- Cross, N. C. P.;
- Haferlach, T.;
- Schnittger, S.
Publication type:
Letter
Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model.
Published in:
2011
By:
- Tamai, H.;
- Miyake, K.;
- Takatori, M.;
- Miyake, N.;
- Yamaguchi, H.;
- Dan, K.;
- Shimada, T.;
- Inokuchi, K.
Publication type:
Letter
Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 838, doi. 10.1038/leu.2011.2
By:
- Huber, S.;
- Oelsner, M.;
- Decker, T.;
- zum Büschenfelde, C. Meyer;
- Wagner, M.;
- Lutzny, G.;
- Kuhnt, T.;
- Schmidt, B.;
- Oostendorp, R. A. J.;
- Peschel, C.;
- Ringshausen, I.
Publication type:
Article
Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 808, doi. 10.1038/leu.2011.13
By:
- Craddock, C.;
- Labopin, M.;
- Pillai, S.;
- Finke, J.;
- Bunjes, D.;
- Greinix, H.;
- Ehninger, G.;
- Steckel, N.-K.;
- Zander, A. R.;
- Schwerdtfeger, R.;
- Buchholz, S.;
- Kolb, H.-J.;
- Volin, L.;
- Fauser, A.;
- Polge, E.;
- Schmid, C.;
- Mohty, M.;
- Rocha, V.
Publication type:
Article
In vitro-established alloantigen-specific CD8<sup>+</sup> CTLs mediate graft-versus-tumor activity in the absence of graft-versus-host disease.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 848, doi. 10.1038/leu.2011.16
By:
- Hartmann, N.;
- Leithäuser, F.;
- Albers, C.;
- Duyster, J.;
- Möller, P.;
- Debatin, K.-M.;
- Strauss, G.
Publication type:
Article
HAX-1 expression in human B lymphoma.
Published in:
2011
By:
- Kwiecinska, A.;
- Ottosson-Wadlund, A.;
- Ceder, R.;
- Grafström, R. C.;
- Björck, E.;
- Nordenskjöld, M.;
- Porwit, A.;
- Fadeel, B.
Publication type:
Letter
Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).
Published in:
2011
By:
- Drakos, E.;
- Singh, R. R.;
- Rassidakis, G. Z.;
- Schlette, E.;
- Li, J.;
- Claret, F. X.;
- Ford, Jr., R. J.;
- Vega, F.;
- Medeiros, L. J.;
- Ford, R J Jr
Publication type:
journal article
Relative fitness of hematopoietic progenitors influences leukemia progression.
Published in:
2011
By:
- Porter, C. C.;
- Baturin, D.;
- Choudhary, R.;
- DeGregori, J.
Publication type:
Letter
p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells.
Published in:
2011
By:
- Peterson, L. F.;
- Mitrikeska, E.;
- Giannola, D.;
- Lui, Y.;
- Sun, H.;
- Bixby, D.;
- Malek, S. N.;
- Donato, N. J.;
- Wang, S.;
- Talpaz, M.
Publication type:
journal article
Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 821, doi. 10.1038/leu.2011.19
By:
- Greif, P. A.;
- Eck, S. H.;
- Konstandin, N. P.;
- Benet-Pagès, A.;
- Ksienzyk, B.;
- Dufour, A.;
- Vetter, A. T.;
- Popp, H. D.;
- Lorenz-Depiereux, B.;
- Meitinger, T.;
- Bohlander, S. K.;
- Strom, T. M.
Publication type:
Article
Phase I study of the anti insulin-like growth factor 1 receptor (IGF-1R) monoclonal antibody, AVE1642, as single agent and in combination with bortezomib in patients with relapsed multiple myeloma.
Published in:
2011
By:
- Moreau, P.;
- Cavallo, F.;
- Leleu, X.;
- Hulin, C.;
- Amiot, M.;
- Descamps, G.;
- Facon, T.;
- Boccadoro, M.;
- Mignard, D.;
- Harousseau, J. L.
Publication type:
Letter
Interferon-α in acute myeloid leukemia: an old drug revisited.
Published in:
Leukemia (08876924), 2011, v. 25, n. 5, p. 739, doi. 10.1038/leu.2010.324
By:
- Anguille, S.;
- Lion, E.;
- Willemen, Y.;
- Van Tendeloo, V. F. I.;
- Berneman, Z. N.;
- Smits, E. L. J. M.
Publication type:
Article
Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720.
Published in:
2011
By:
- Baer, M. R.;
- George, S. L.;
- Sanford, B. L.;
- Mrózek, K.;
- Kolitz, J. E.;
- Moore, J. O.;
- Stone, R. M.;
- Powell, B. L.;
- Caligiuri, M. A.;
- Bloomfield, C. D.;
- Larson, R. A.;
- Mrózek, K;
- Cancer and Leukemia Group B
Publication type:
journal article
Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.
Published in:
2011
By:
- Vandewoestyne, M. L.;
- Pede, V. C.;
- Lambein, K. Y.;
- Dhaenens, M. F.;
- Offner, F. C.;
- Praet, M. M.;
- Philippé, J. J.;
- Kipps, T. J.;
- Deforce, D. L.
Publication type:
Letter
Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy.
Published in:
2011
By:
- Tuve, S.;
- Gayoso, J.;
- Scheid, C.;
- Radke, J.;
- Kiani, A.;
- Serrano, D.;
- Platzbecker, U.;
- Rodríguez-Macías, G.;
- Wermke, M.;
- Holtick, U.;
- Balsalobre, P.;
- Middeke, J. M.;
- Shayegi, N.;
- Chemnitz, J. M.;
- Krause, A.;
- Gruner, N.;
- Füssel, M.;
- Schetelig, J.;
- Thiede, C.;
- Ehninger, G.
Publication type:
Letter
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia.
Published in:
2011
By:
- Coles, S. J.;
- Wang, E. C. Y.;
- Man, S.;
- Hills, R. K.;
- Burnett, A. K.;
- Tonks, A.;
- Darley, R. L.
Publication type:
journal article
The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha.
Published in:
2011
By:
- Occhionorelli, M.;
- Santoro, F.;
- Pallavicini, I.;
- Gruszka, A.;
- Moretti, S.;
- Bossi, D.;
- Viale, A.;
- Shing, D.;
- Ronzoni, S.;
- Muradore, I.;
- Soncini, M.;
- Pruneri, G.;
- Rafaniello, P.;
- Viale, G.;
- Pelicci, P. G.;
- Minucci, S.
Publication type:
journal article
Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.
Published in:
2011
By:
- Gandillet, A.;
- Park, S.;
- Lassailly, F.;
- Griessinger, E.;
- Vargaftig, J.;
- Filby, A.;
- Lister, T. A.;
- Bonnet, D.;
- Gandillet, Arnaud;
- Park, Sophie;
- Lassailly, François;
- Griessinger, Emmanuel;
- Vargaftig, Jacques;
- Filby, Andrew;
- Lister, T Andrew;
- Bonnet, Dominique
Publication type:
journal article

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