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Proliferation centers in chronic lymphocytic leukemia: the niche where NF-κB activation takes place.
Published in:
2010
By:
- Herreros, B.;
- Rodríguez-Pinilla, S. M.;
- Pajares, R.;
- Martínez-Gónzalez, M. Á;
- Ramos, R.;
- Munoz, I.;
- Montes-Moreno, S.;
- Lozano, M.;
- Sánchez-Verde, L.;
- Roncador, G.;
- Sánchez-Beato, M.;
- de Otazu, R. D.;
- Pérez-Guillermo, M.;
- Mestre, M. J.;
- Bellas, C.;
- Piris, M. Á
Publication type:
Letter
ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence.
Published in:
2010
By:
- Yang, W.;
- Treviño, L. R.;
- Yang, J. J.;
- Scheet, P.;
- Pui, C.-H.;
- Evans, W. E.;
- Relling, M. V.;
- Treviño, L R
Publication type:
Letter
A novel exon in AML1-ETO negatively influences the clonogenic potential of the t(8;21) in acute myeloid leukemia.
Published in:
2010
By:
- Mannari, D.;
- Gascoyne, D.;
- Dunne, J.;
- Chaplin, T.;
- Young, B.
Publication type:
Letter
Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.
Published in:
2010
By:
- Wang, S. A.;
- Jabbar, K.;
- Lu, G.;
- Chen, S. S.;
- Galili, N.;
- Vega, F.;
- Jones, D.;
- Raza, A.;
- Kantarjian, H.;
- Garcia-Manero, G.;
- McDonnell, T. J.;
- Medeiros, L. J.
Publication type:
journal article
The NDE1 gene is disrupted by the inv(16) in 90% of cases with CBFB–MYH11-positive acute myeloid leukemia.
Published in:
2010
By:
- Van der Reijden, B. A.;
- Massop, M.;
- Simons, A.;
- de Witte, T.;
- Breuning, M.;
- Jansen, J. H.
Publication type:
Letter
NHR4 domain mutations of ETO are probably very infrequent in AML1-ETO positive myeloid leukemia cells.
Published in:
2010
By:
- Hackanson, B.;
- Abdelkarim, M.;
- Jansen, J. H.;
- Lübbert, M.;
- Lübbert, M
Publication type:
Letter
Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 699, doi. 10.1038/leu.2009.292
By:
- Lancet, J. E.;
- Gojo, I.;
- Burton, M.;
- Quinn, M.;
- Tighe, S. M.;
- Kersey, K.;
- Zhong, Z.;
- Albitar, M. X.;
- Bhalla, K.;
- Hannah, A. L.;
- Baer, M. R.
Publication type:
Article
Identification of activated Tnk1 kinase in Hodgkin's lymphoma.
Published in:
2010
By:
- Gu, T.-L.;
- Cherry, J.;
- Tucker, M;
- Wu, J.;
- Reeves, C.;
- Polakiewicz, R. D.
Publication type:
Letter
Biclonal origin prevails in concomitant chronic lymphocytic leukemia and multiple myeloma.
Published in:
2010
By:
- Pantic, M.;
- Schroettner, P.;
- Pfeifer, D.;
- Rawluk, J.;
- Denz, U.;
- Schmitt-Gräff, A.;
- Veelken, H.;
- Wäsch, R.;
- Engelhardt, M.
Publication type:
Letter
Serum metabolome analysis by <sup>1</sup>H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 788, doi. 10.1038/leu.2009.295
By:
- MacIntyre, D. A.;
- Jiménez, B.;
- Lewintre, E. Jantus;
- Martín, C. Reinoso;
- Schäfer, H.;
- Ballesteros, C. García;
- Mayans, J. Ramón;
- Spraul, M.;
- García-Conde, J.;
- Pineda-Lucena, A.
Publication type:
Article
Lenalidomide induces cell death in an MDS-derived cell line with deletion of chromosome 5q by inhibition of cytokinesis.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 748, doi. 10.1038/leu.2009.296
By:
- Matsuoka, A.;
- Tochigi, A.;
- Kishimoto, M.;
- Nakahara, T.;
- Kondo, T.;
- Tsujioka, T.;
- Tasaka, T.;
- Tohyama, Y.;
- Tohyama, K.
Publication type:
Article
The use of low-dose alemtuzumab in pretreated B-cell chronic lymphocytic leukemia.
Published in:
2010
By:
- Tarnani, M.;
- D'Arena, G.;
- Efremov, D. G.;
- Marietti, S.;
- S., Sica;
- Leone, G.;
- Laurenti, L.
Publication type:
Letter
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia.
Published in:
2010
By:
- Allan, J. M.;
- Sunter, N. J.;
- Bailey, J. R.;
- Pettitt, A. R.;
- Harris, R. J.;
- Pepper, C.;
- Fegan, C.;
- Hall, A. G.;
- Deignan, L.;
- Bacon, C. M.;
- Pointon, J. C.;
- Houlston, R. S.;
- Broderick, P.;
- Mainou-Fowler, T.;
- Jackson, G. H.;
- Summerfield, G.;
- Evans, P. A.;
- Strefford, J. C.;
- Parker, A.;
- Oscier, D.
Publication type:
Letter
Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 771, doi. 10.1038/leu.2009.299
By:
- Hiwase, D. K.;
- White, D. L.;
- Powell, J. A.;
- Saunders, V. A.;
- Zrim, S. A.;
- Frede, A. K.;
- Guthridge, M. A.;
- Lopez, A. F.;
- D'Andrea, R. J.;
- To, L. B.;
- Melo, J. V.;
- Kumar, S.;
- Hughes, T. P.
Publication type:
Article
ON012380, a putative BCR-ABL kinase inhibitor with a unique mechanism of action in imatinib-resistant cells.
Published in:
2010
By:
- Wu, J.;
- Meng, F.;
- Ying, Y.;
- Peng, Z.;
- Daniels, L.;
- Bornmann, W. G.;
- Quintás-Cardama, A.;
- Roulston, D.;
- Talpaz, M.;
- Peterson, L. F.;
- Donato, N. J.;
- Quintás-Cardama, A
Publication type:
Letter
FES kinases are required for oncogenic FLT3 signaling.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 721, doi. 10.1038/leu.2009.301
By:
- Voisset, E.;
- Lopez, S.;
- Chaix, A.;
- Georges, C.;
- Hanssens, K.;
- Prébet, T.;
- Dubreuil, P.;
- De Sepulveda, P.
Publication type:
Article
Development of resistance to dasatinib in Bcr/Abl-positive acute lymphoblastic leukemia.
Published in:
2010
By:
- Fei, F.;
- Stoddart, S.;
- Müschen, M.;
- Kim, Y.-M.;
- Groffen, J.;
- Heisterkamp, N.;
- Müschen, M
Publication type:
journal article
The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 715, doi. 10.1038/leu.2009.303
By:
- Schmiegelow, K.;
- Heyman, M.;
- Gustafsson, G.;
- Lausen, B.;
- Wesenberg, F.;
- Kristinsson, J.;
- Vettenranta, K.;
- Schroeder, H.;
- Forestier, E.;
- Rosthoej, S.
Publication type:
Article
Chronic lymphoproliferative disorder of natural killer cells: a distinct entity with subtypes correlating with normal natural killer cell subsets.
Published in:
2010
By:
- Morice, W. G.;
- Jevremovic, D.;
- Olteanu, H.;
- Roden, A.;
- Nowakowski, G.;
- Kroft, S.;
- Hanson, C. A.;
- Kurtin, P. J.
Publication type:
Letter
Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 671, doi. 10.1038/leu.2010.15
By:
- Moore, A. S.;
- Blagg, J.;
- Linardopoulos, S.;
- Pearson, A. D. J.
Publication type:
Article
Lck is a key target of imatinib and dasatinib in T-cell activation.
Published in:
2010
By:
- Lee, K. C.;
- Ouwehand, I.;
- Giannini, A. L.;
- Thomas, N. S.;
- Dibb, N. J.;
- Bijlmakers, M. J.
Publication type:
Letter
Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 843, doi. 10.1038/leu.2010.25
By:
- Kobayashi, T.;
- Kuroda, J.;
- Ashihara, E.;
- Oomizu, S.;
- Terui, Y.;
- Taniyama, A.;
- Adachi, S.;
- Takagi, T.;
- Yamamoto, M.;
- Sasaki, N.;
- Horiike, S.;
- Hatake, K.;
- Yamauchi, A.;
- Hirashima, M.;
- Taniwaki, M.
Publication type:
Article
Targeting PKCδ-mediated topoisomerase IIβ overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 729, doi. 10.1038/leu.2010.27
By:
- McNamara, S.;
- Nichol, J. N.;
- Wang, H.;
- Miller, W. H.
Publication type:
Article
Partial retraction. VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance.
Published in:
2010
By:
- Lee, Y K;
- Shanafelt, T D;
- Bone, N D;
- Strege, A K;
- Jelinek, D F;
- Kay, N E
Publication type:
corrected article
Monitoring of adenovirus load in stool by real-time PCR permits early detection of impending invasive infection in patients after allogeneic stem cell transplantation.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 706, doi. 10.1038/leu.2010.4
By:
- Lion, T.;
- Kosulin, K.;
- Landlinger, C.;
- Rauch, M.;
- Preuner, S.;
- Jugovic, D.;
- Pötschger, U.;
- Lawitschka, A.;
- Peters, C.;
- Fritsch, G.;
- Matthes-Martin, S.
Publication type:
Article
Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment.
Published in:
2010
By:
- Jung, R.;
- Jacobs, U.;
- Krumbholz, M.;
- Langer, T.;
- Keller, T.;
- De Lorenzo, P.;
- Valsecchi, M. G.;
- van der Velden, V. H. J.;
- Moericke, A.;
- Stanulla, M.;
- Teigler-Schlegel, A.;
- Panzer-Gruemayer, E. R.;
- van Dongen, J. J. M.;
- Schrappe, M.;
- den Boer, M. L.;
- Pieters, R.;
- Rascher, W.;
- Metzler, M.
Publication type:
Letter
MPL mutation effect on JAK2 46/1 haplotype frequency in JAK2V617F-negative myeloproliferative neoplasms.
Published in:
2010
By:
- Patnaik, M. M.;
- Lasho, T. L.;
- Finke, C. M.;
- Gangat, N.;
- Caramazza, D.;
- Siragusa, S.;
- Hanson, C. A.;
- Pardanani, A.;
- Tefferi, A.
Publication type:
Letter
Chronic Myeloid Leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 Activity.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 765, doi. 10.1038/leu.2010.16
By:
- Engler, J. R.;
- Frede, A.;
- Saunders, V. A.;
- Zannettino, A. C. W.;
- Hughes, T. P.;
- White, D. L.
Publication type:
Article
gammaH2AX: a sensitive molecular marker of DNA damage and repair.
Published in:
2010
By:
- Mah, L.-J.;
- El-Osta, A.;
- Karagiannis, T. C.
Publication type:
journal article
Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma.
Published in:
2010
By:
- Chng, W. J.;
- Gertz, M. A.;
- Chung, T.-H.;
- Van Wier, S.;
- Keats, J. J.;
- Baker, A.;
- Bergsagel, P. L.;
- Carpten, J.;
- Fonseca, R.
Publication type:
journal article
Role of BCR-ABL-Y177-mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors.
Published in:
2010
By:
- Chu, S.;
- McDonald, T.;
- Bhatia, R.
Publication type:
journal article
NF-kappaB activation mediates resistance to IFN beta in MLL-rearranged acute lymphoblastic leukemia.
Published in:
2010
By:
- Tracey, L.;
- Streck, C. J.;
- Du, Z.;
- Williams, R. F.;
- Pfeffer, L. M.;
- Nathwani, A. C.;
- Davidoff, A. M.
Publication type:
journal article
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 687, doi. 10.1038/leu.2010.32
By:
- Martelli, A. M.;
- Papa, V.;
- Tazzari, P. L.;
- Ricci, F.;
- Evangelisti, C.;
- Chiarini, F.;
- Grimaldi, C.;
- Cappellini, A.;
- Martinelli, G.;
- Ottaviani, E.;
- Pagliaro, P.;
- Horn, S.;
- Bäsecke, J.;
- Lindner, L. H.;
- Eibl, H.;
- McCubrey, J. A.
Publication type:
Article
Nucleoside analog ARC targets Mcl-1 to induce apoptosis in leukemia cells.
Published in:
2010
By:
- Bhat, U. G.;
- Gartel, A. L.
Publication type:
Letter
Peptide vaccination elicits leukemia-associated antigen-specific cytotoxic CD8+ T-cell responses in patients with chronic lymphocytic leukemia.
Published in:
2010
By:
- Giannopoulos, K.;
- Dmoszynska, A.;
- Kowal, M.;
- Rolinski, J.;
- Gostick, E.;
- Price, D. A.;
- Greiner, J.;
- Rojewski, M.;
- Stilgenbauer, S.;
- Döhner, H.;
- Schmitt, M.;
- Döhner, H
Publication type:
journal article
Leukocytosis is associated with poor survival but not with increased risk of thrombosis in essential thrombocythemia: a population-based study of 311 patients.
Published in:
2010
By:
- Girodon, F.;
- Dutrillaux, F.;
- Broséus, J.;
- Mounier, M.;
- Goussot, V.;
- Bardonnaud, P.;
- Chrétien, M. L.;
- Maynadié, M.
Publication type:
Letter
Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells.
Published in:
Leukemia (08876924), 2010, v. 24, n. 4, p. 756, doi. 10.1038/leu.2010.31
By:
- Pellagatti, A.;
- Cazzola, M.;
- Giagounidis, A.;
- Perry, J.;
- Malcovati, L.;
- Della Porta, M. G.;
- Jädersten, M.;
- Killick, S.;
- Verma, A.;
- Norbury, C. J.;
- Hellström-Lindberg, E.;
- Wainscoat, J. S.;
- Boultwood, J.
Publication type:
Article
Nilotinib does not significantly reduce imatinib OCT-1 activity in either cell lines or primary CML cells.
Published in:
2010
By:
- Eadie, L.;
- Hughes, T. P.;
- White, D. L.
Publication type:
research
Specific induction of CD33 expression by E2A–HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor.
Published in:
2010
By:
- Akahane, K.;
- Inukai, T.;
- Inaba, T.;
- Kurosawa, H.;
- Look, A. T.;
- Kiyokawa, N.;
- Fujimoto, J.;
- Goto, H.;
- Endo, M.;
- Zhang, X.;
- Hirose, K.;
- Kuroda, I.;
- Honna, H.;
- Kagami, K.;
- Goi, K.;
- Nakazawa, S.;
- Sugita, K.
Publication type:
Letter
SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity.
Published in:
2010
By:
- Charlier, E.;
- Condé, C.;
- Zhang, J.;
- Deneubourg, L.;
- Di Valentin, E.;
- Rahmouni, S.;
- Chariot, A.;
- Agostinis, P.;
- Pang, P.-C.;
- Haslam, S. M.;
- Dell, A.;
- Penninger, J.;
- Erneux, C.;
- Piette, J.;
- Gloire, G.;
- Condé, C
Publication type:
journal article

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