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Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR–ABL1-positive acute lymphoblastic leukemia patients.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 66, doi. 10.1038/leu.2009.197
By:
- Iacobucci, I.;
- Lonetti, A.;
- Messa, F.;
- Ferrari, A.;
- Cilloni, D.;
- Soverini, S.;
- Paoloni, F.;
- Arruga, F.;
- Ottaviani, E.;
- Chiaretti, S.;
- Messina, M.;
- Vignetti, M.;
- Papayannidis, C.;
- Vitale, A.;
- Pane, F.;
- Piccaluga, P. P.;
- Paolini, S.;
- Berton, G.;
- Baruzzi, A.;
- Saglio, G.
Publication type:
Article
TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p.
Published in:
2010
By:
- Jasek, M.;
- Gondek, L. P.;
- Bejanyan, N.;
- Tiu, R.;
- Huh, J.;
- Theil, K. S.;
- O'Keefe, C.;
- McDevitt, M. A.;
- Maciejewski, J. P.
Publication type:
Letter
Myelodysplastic syndromes: lost between two states?
Published in:
2010
By:
- Acquaviva, C.;
- Gelsi-Boyer, V.;
- Birnbaum, D.
Publication type:
Editorial
Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias.
Published in:
2010
By:
- Couronné, L.;
- Lippert, E.;
- Andrieux, J.;
- Kosmider, O.;
- Radford-Weiss, I.;
- Penther, D.;
- Dastugue, N.;
- Mugneret, F.;
- Lafage, M.;
- Gachard, N.;
- Nadal, N.;
- Bernard, O. A.;
- Nguyen-Khac, F.;
- Couronné, L
Publication type:
Letter
Identification of a novel TEL–Lyn fusion gene in primary myelofibrosis.
Published in:
2010
By:
- Tanaka, H.;
- Takeuchi, M.;
- Takeda, Y.;
- Sakai, S.;
- Abe, D.;
- Ohwada, C.;
- Sakaida, E.;
- Shimizu, N.;
- Saito, Y.;
- Miyagi, S.;
- Iwama, A.;
- Nakaseko, C.
Publication type:
Letter
Stem cell traits in long-term co-culture revealed by time-lapse imaging.
Published in:
2010
By:
- Song, Y.;
- Bahnson, A.;
- Hall, N.;
- Yu, H.;
- Shen, H.;
- Koebler, D.;
- Houck, R.;
- Xie, Y.;
- Cheng, T.
Publication type:
journal article
Extensive mutational status of genes and clinical outcome in pediatric acute myeloid leukemia.
Published in:
2010
By:
- Lapillonne, H.;
- Llopis, L.;
- Auvrignon, A.;
- Renneville, A.;
- Labopin, M.;
- Mazingue, F.;
- Perot, C.;
- Lai, J.-L.;
- Philippe, N.;
- Ballerini, P.;
- Zurawski, V.;
- Adam, M.;
- Douay, L.;
- Leverger, G.;
- Landman-Parker, J.;
- Preudhomme, C.
Publication type:
Letter
Characterizing chromosomal break points of t(12;21)[ETV6–RUNX1]-positive leukaemia using multiple tiling PCR on whole-genome-amplified DNA.
Published in:
2010
By:
- Lausten-Thomsen, U.;
- Madsen, H. O.;
- Schmiegelow, K.
Publication type:
Letter
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 125, doi. 10.1038/leu.2009.186
By:
- Darzentas, N.;
- Hadzidimitriou, A.;
- Murray, F.;
- Hatzi, K.;
- Josefsson, P.;
- Laoutaris, N.;
- Moreno, C.;
- Anagnostopoulos, A.;
- Jurlander, J.;
- Tsaftaris, A.;
- Chiorazzi, N.;
- Belessi, C.;
- Ghia, P.;
- Rosenquist, R.;
- Davi, F.;
- Stamatopoulos, K.
Publication type:
Article
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients.
Published in:
2010
By:
- Gunnarsson, R.;
- Isaksson, A.;
- Mansouri, M.;
- Göransson, H.;
- Jansson, M.;
- Cahill, N.;
- Rasmussen, M.;
- Staaf, J.;
- Lundin, J.;
- Norin, S.;
- Buhl, A. M.;
- Smedby, K. E.;
- Hjalgrim, H.;
- Karlsson, K.;
- Jurlander, J.;
- Juliusson, G.;
- Rosenquist, R.
Publication type:
Letter
Identification of native, immunogenic peptides from Cyclin D1.
Published in:
2010
By:
- von Bergwelt-Baildon, M. S.;
- Shimabukuro-Vornhagen, A.;
- Wendtner, C. M.;
- Kondo, E.
Publication type:
Letter
Inhibition of Syk protein tyrosine kinase induces apoptosis and blocks proliferation in T-cell non-Hodgkin's lymphoma cell lines.
Published in:
2010
By:
- Wilcox, R. A.;
- Sun, D. X.;
- Novak, A.;
- Dogan, A.;
- Ansell, S. M.;
- Feldman, A. L.
Publication type:
Letter
A phase I/II trial of TLR-7 agonist immunotherapy in chronic lymphocytic leukemia.
Published in:
2010
By:
- Spaner, D. E.;
- Shi, Y.;
- White, D.;
- Shaha, S.;
- He, L.;
- Masellis, A.;
- Wong, K.;
- Gorczynski, R.
Publication type:
Letter
The function of the pleckstrin homology domain in BCR–ABL-mediated leukemogenesis.
Published in:
2010
By:
- Demehri, S.;
- O'Hare, T.;
- Eide, C. A.;
- Smith, C. A.;
- Tyner, J. W.;
- Druker, B. J.;
- Deininger, M. W. N.
Publication type:
Letter
Low or undetectable numbers of Philadelphia chromosome-positive leukemic stem cells (Ph+CD34+CD38neg) in chronic myeloid leukemia patients in complete cytogenetic remission after tyrosine kinase inhibitor therapy.
Published in:
2010
By:
- Mustjoki, S.;
- Rohon, P.;
- Rapakko, K.;
- Jalkanen, S.;
- Koskenvesa, P.;
- Lundán, T.;
- Porkka, K.
Publication type:
Letter
Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib: weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history.
Published in:
2010
By:
- Jabbour, E.;
- Hochhaus, A.;
- Cortes, J.;
- La Rosée, P.;
- Kantarjian, H. M.;
- La Rosée, P
Publication type:
journal article
Single-cell analysis reveals oligoclonality among 'low-count' monoclonal B-cell lymphocytosis.
Published in:
2010
By:
- Lanasa, M. C.;
- Allgood, S. D.;
- Volkheimer, A. D.;
- Gockerman, J. P.;
- Whitesides, J. F.;
- Goodman, B. K.;
- Moore, J. O.;
- Weinberg, J. B.;
- Levesque, M. C.
Publication type:
journal article
Analysis of factors that affect in vitro chemosensitivity of leukaemic stem and progenitor cells to gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukaemia.
Published in:
2010
By:
- Jawad, M.;
- Seedhouse, C.;
- Mony, U.;
- Grundy, M.;
- Russell, N. H.;
- Pallis, M.
Publication type:
journal article
EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 81, doi. 10.1038/leu.2009.202
By:
- Goyama, S.;
- Nitta, E.;
- Yoshino, T.;
- Kako, S.;
- Watanabe-Okochi, N.;
- Shimabe, M.;
- Imai, Y.;
- Takahashi, K.;
- Kurokawa, M.
Publication type:
Article
Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia.
Published in:
2010
By:
- Jotta, P. Y.;
- Ganazza, M. A.;
- Silva, A.;
- Viana, M. B.;
- da Silva, M. J.;
- Zambaldi, L. J. G.;
- Barata, J. T.;
- Brandalise, S. R.;
- Yunes, J. A.
Publication type:
Letter
PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy.
Published in:
2010
By:
- Molteni, C. G.;
- te Kronnie, G.;
- Bicciato, S.;
- Villa, T.;
- Tartaglia, M.;
- Basso, G.;
- Biondi, A.;
- Cazzaniga, G.
Publication type:
Letter
Novel RUNX1 mutations in familial platelet disorder with enhanced risk for acute myeloid leukemia: clues for improved identification of the FPD/AML syndrome.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 242, doi. 10.1038/leu.2009.210
By:
- Jongmans, M. C. J.;
- Kuiper, R. P.;
- Carmichael, C. L.;
- Wilkins, E. J.;
- Dors, N.;
- Carmagnac, A.;
- Schouten-van Meeteren, A. Y. N.;
- Li, X.;
- Stankovic, M.;
- Kamping, E.;
- Bengtsson, H.;
- Schoenmakers, E. F. P. M.;
- van Kessel, A. Geurts;
- Hoogerbrugge, P. M.;
- Hahn, C. N.;
- Brons, P. P.;
- Scott, H. S.;
- Hoogerbrugge, N.
Publication type:
Article
DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 169, doi. 10.1038/leu.2009.203
By:
- Bardini, M.;
- Spinelli, R.;
- Bungaro, S.;
- Mangano, E.;
- Corral, L.;
- Cifola, I.;
- Fazio, G.;
- Giordan, M.;
- Basso, G.;
- De Rossi, G.;
- Biondi, A.;
- Battaglia, C.;
- Cazzaniga, G.
Publication type:
Article
Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma.
Published in:
2010
By:
- Quach, H.;
- Ritchie, D.;
- Stewart, A. K.;
- Neeson, P.;
- Harrison, S.;
- Smyth, M. J.;
- Prince, H. M.
Publication type:
journal article
Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles.
Published in:
2010
By:
- Shaw, B. E.;
- Mayor, N. P.;
- Russell, N. H.;
- Apperley, J. F.;
- Clark, R. E.;
- Cornish, J.;
- Darbyshire, P.;
- Ethell, M. E.;
- Goldman, J. M.;
- Little, A.-M.;
- Mackinnon, S.;
- Marks, D. I.;
- Pagliuca, A.;
- Thomson, K.;
- Marsh, S. G. E.;
- Madrigal, J. A.
Publication type:
journal article
Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine.
Published in:
2010
By:
- Wermke, M.;
- Thiede, C.;
- Kiani, A.;
- Ehninger, G.;
- Bornhäuser, M.;
- Platzbecker, U.
Publication type:
Letter
Oral fludarabine in untreated patients with B-cell chronic lymphocytic leukemia.
Published in:
2010
By:
- Shustik, C.;
- Turner, A. R.;
- Desjardins, P.;
- Fernandez, L.;
- Rubin, S.;
- Larratt, L.;
- Duncan, A. M. V.;
- Rizi, D.;
- Sadura, A.;
- Shepherd, L.;
- Li, D.;
- Rassenti, L.;
- Kipps, T.
Publication type:
Letter
In vivo dynamics of human cord blood-derived CD34− SCID-repopulating cells using intra-bone marrow injection.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 162, doi. 10.1038/leu.2009.206
By:
- Kimura, T.;
- Matsuoka, Y.;
- Murakami, M.;
- Takahashi, M.;
- Nakamoto, T.;
- Yasuda, K.;
- Matsui, K.;
- Kobayashi, K.;
- Imai, S.;
- Asano, H.;
- Nakatsuka, R.;
- Uemura, Y.;
- Sasaki, Y.;
- Sonoda, Y.
Publication type:
Article
Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53.
Published in:
2010
By:
- Gefen, N.;
- Binder, V.;
- Zaliova, M.;
- Linka, Y.;
- Morrow, M.;
- Novosel, A.;
- Edry, L.;
- Hertzberg, L.;
- Shomron, N.;
- Williams, O.;
- Trka, J.;
- Borkhardt, A.;
- Izraeli, S.
Publication type:
journal article
Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1/Noxa axis.
Published in:
2010
By:
- Kojima, K.;
- Konopleva, M.;
- Tsao, T.;
- Andreeff, M.;
- Ishida, H.;
- Shiotsu, Y.;
- Jin, L.;
- Tabe, Y.;
- Nakakuma, H.
Publication type:
journal article
Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells.
Published in:
2010
By:
- Brugat, T.;
- Gault, N.;
- Baccelli, I.;
- Maës, J.;
- Roborel de Climens, A.;
- Nguyen-Khac, F.;
- Davi, F.;
- Merle-Béral, H.;
- Gilson, E.;
- Goodhardt, M.;
- Delic, J.
Publication type:
Letter
Recruitment of PKC-βII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 141, doi. 10.1038/leu.2009.216
By:
- Meyer zum Büschenfelde, C.;
- Wagner, M.;
- Lutzny, G.;
- Oelsner, M.;
- Feuerstacke, Y.;
- Decker, T.;
- Bogner, C.;
- Peschel, C.;
- Ringshausen, I.
Publication type:
Article
Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia.
Published in:
2010
By:
- Sanchez-Aguilera, A.;
- Rattmann, I.;
- Drew, D. Z.;
- Müller, L. U. W.;
- Summey, V.;
- Lucas, D. M.;
- Byrd, J. C.;
- Croce, C. M.;
- Gu, Y.;
- Cancelas, J. A.;
- Johnston, P.;
- Moritz, T.;
- Williams, D. A.;
- Müller, L U W
Publication type:
journal article
Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways.
Published in:
2010
By:
- Zhao, W.-L.
Publication type:
journal article
WAVE1 regulates Bcl-2 localization and phosphorylation in leukemia cells.
Published in:
2010
By:
- Kang, R.;
- Tang, D.;
- Yu, Y.;
- Wang, Z.;
- Hu, T.;
- Wang, H.;
- Cao, L.
Publication type:
journal article
JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 105, doi. 10.1038/leu.2009.225
By:
- Tefferi, A.;
- Lasho, T. L.;
- Patnaik, M. M.;
- Finke, C. M.;
- Hussein, K.;
- Hogan, W. J.;
- Elliott, M. A.;
- Litzow, M. R.;
- Hanson, C. A.;
- Pardanani, A.
Publication type:
Article
The JAK2 46/1 haplotype confers susceptibility to essential thrombocythemia regardless of JAK2V617F mutational status—clinical correlates in a study of 226 consecutive patients.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 110, doi. 10.1038/leu.2009.226
By:
- Pardanani, A.;
- Lasho, T. L.;
- Finke, C. M.;
- Gangat, N.;
- Wolanskyj, A. P.;
- Hanson, C. A.;
- Tefferi, A.
Publication type:
Article
Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells.
Published in:
2010
By:
- Belardo, G.;
- Piva, R.;
- Santoro, M. G.
Publication type:
journal article
A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells.
Published in:
2010
By:
- Rix, U.;
- Rix, L. L. Remsing;
- Terker, A. S.;
- Fernbach, N. V.;
- Hantschel, O.;
- Planyavsky, M.;
- Breitwieser, F. P.;
- Herrmann, H.;
- Colinge, J.;
- Bennett, K. L.;
- Augustin, M.;
- Till, J. H.;
- Heinrich, M. C.;
- Valent, P.;
- Superti^Furga, G.;
- Remsing Rix, L L
Publication type:
journal article
TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species.
Published in:
2010
By:
- Vahdat, A. M.;
- Reiners, K. S.;
- Simhadri, V. L.;
- Eichenauer, D. A.;
- Böll, B.;
- Chalaris, A.;
- Simhadri, V. R.;
- Wiegmann, K.;
- Krell, H.-W.;
- John, S. Rose;
- Engert, A.;
- von Strandmann, E. P.;
- Hansen, H. P.;
- Böll, B;
- Rose-John, S
Publication type:
journal article
Cathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR–ABL cleavage and elimination of chronic myelogenous leukemia cells.
Published in:
Leukemia (08876924), 2010, v. 24, n. 1, p. 115, doi. 10.1038/leu.2009.233
By:
- Puissant, A.;
- Colosetti, P.;
- Robert, G.;
- Cassuto, J.-P.;
- Raynaud, S.;
- Auberger, P.
Publication type:
Article

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