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Circadian Rhythms of Human Pineal Melatonin, Related Indoles, and Beta Adrenoreceptors: Post-Mortem Evaluation.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 1, doi. 10.1111/j.1600-079X.1990.tb00688.x
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- Article
Light Suppression of Melatonin in the Squirrel Monkey ( Saimiri sciureus).
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 13, doi. 10.1111/j.1600-079X.1990.tb00689.x
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- Article
Alpha-1 Adrenoceptor Involvement in the Control of Melatonin Secretion in the Golden Hamster.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 21, doi. 10.1111/j.1600-079X.1990.tb00690.x
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- Article
Choline Acetyltransferase in Bovine Pineal Gland.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 29, doi. 10.1111/j.1600-079X.1990.tb00691.x
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- Article
Saliva and serum samples were collected from eight healthy volunteers every two hours during a 26-hour period. Melatonin concentrations were measured by radioimmunoassay after chloroform extraction using radioiodinated melatonin as a tracer. Five of the subjects had high serum melatonin levels at night (peak levels higher than 75 pg/ml); in three subjects the highest serum melatonin concentration was 20-40 pg/ml. All subjects had low levels (<10 pg/ml) during the day. The correlations between salivary and serum levels were calculated. The regression line y =0.33×+ 3.7 pg/ml, r= 0.95, P <0.001, was obtained for all detectable value pairs (n= 73). The regression and correlation coefficients were almost equal for the peak values of melatonin and during the rising and descending phases of the secretion patterns. However, no significant correlation was found between low daytime salivary and serum concentrations when calculated separately. In the five high-secretors the melatonin levels in saliva reflected reliably the changes in serum, but in the three low-secretors the correlation between salivary and serum melatonin was not significant. The proportion of melatonin found in saliva decreased with increasing serum melatonin levels. Circadian rhythm parameters were estimated by single cosinor analysis. The acrophases did not differ significantly within a subject in the concomitant measurements of serum and salivary melatonin. The measurements of salivary melatonin levels seem valid for studies on melatonin rhythms, but the melatonin concentrations measured in saliva do not always consistently reflect the absolute concentrations in blood.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 39, doi. 10.1111/j.1600-079X.1990.tb00692.x
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- Article
Time-Dependent Effect of Melatonin on Actin mRNA Levels and Incorporation of <sup>35</sup>S-Methionine Into Actin and Proteins by the Rat Hypothalamus.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 51, doi. 10.1111/j.1600-079X.1990.tb00693.x
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- Article
Pineal Gland Free Amino Acids and Indoles During Postnatal Development of the Rat: Correlations in Individual Glands.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 65, doi. 10.1111/j.1600-079X.1990.tb00694.x
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- Article
Propranolol Blockade of Short Photoperiod-Induced Gonadal Regression: Modification by Melatonin Injections or Implants.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 75, doi. 10.1111/j.1600-079X.1990.tb00695.x
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- Article
Thymidine Incorporation by Chick Pineal Glands as Studied by Pulse-Labelling In Vitro.
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- Journal of Pineal Research, 1990, v. 9, n. 1, p. 85, doi. 10.1111/j.1600-079X.1990.tb00696.x
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- Article