Works matching IS 07248741 AND DT 2022 AND VI 39 AND IP 7

Results: 26

Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer's Disease in Rat and Dog.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1497, doi. 10.1007/s11095-022-03285-z

By:

Lessard, Etienne;
Rennie, Kerry;
Haqqani, Arsalan;
Ling, Binbing;
Whitfield, James;
Paradis, Andrea;
Araujo, Joseph;
Yoganathan, Nathan;
Gillard, John;
Stanimirovic, Danica;
Chakravarthy, Balu

Publication type:

Article

Transferrin Receptor Binding BBB-Shuttle Facilitates Brain Delivery of Anti-Aβ-Affibodies.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1509, doi. 10.1007/s11095-022-03282-2

By:

Faresjö, Rebecca;
Lindberg, Hanna;
Ståhl, Stefan;
Löfblom, John;
Syvänen, Stina;
Sehlin, Dag

Publication type:

Article

Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC<sub>50</sub> Values in Aging and Alzheimer's Disease, Using the Physiologically Based LeiCNS-PK3.0 Model.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1303, doi. 10.1007/s11095-022-03281-3

By:

Saleh, Mohammed A. A.;
Bloemberg, Julia S.;
Elassaiss-Schaap, Jeroen;
de Lange, Elizabeth C. M.

Publication type:

Article

Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1283, doi. 10.1007/s11095-022-03279-x

By:

Loryan, Irena;
Smith, David E.;
Artursson, Per;
Breimer, Douwe;
Deguchi, Yoshiharu;
Paalzow, Lennart;
Sugiyama, Yuichi;
Terasaki, Tetsuya;
de Lange, Elizabeth C. M.

Publication type:

Article

Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1291, doi. 10.1007/s11095-022-03278-y

By:

Syvänen, Stina;
Fridén, Markus

Publication type:

Article

PET Imaging in Preclinical Anti-Aβ Drug Development.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1481, doi. 10.1007/s11095-022-03277-z

By:

Syvänen, Stina;
Meier, Silvio R.;
Roshanbin, Sahar;
Xiong, Mengfei;
Faresjö, Rebecca;
Gustavsson, Tobias;
Bonvicini, Gillian;
Schlein, Eva;
Aguilar, Ximena;
Julku, Ulrika;
Eriksson, Jonas;
Sehlin, Dag

Publication type:

Article

Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1393, doi. 10.1007/s11095-022-03275-1

By:

Takeuchi, Hina;
Suzuki, Masayoshi;
Goto, Ryohei;
Tezuka, Kenta;
Fuchs, Holger;
Ishiguro, Naoki;
Terasaki, Tetsuya;
Braun, Clemens;
Uchida, Yasuo

Publication type:

Article

Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1457, doi. 10.1007/s11095-022-03266-2

By:

Kucharz, Krzysztof;
Kutuzov, Nikolay;
Zhukov, Oleg;
Mathiesen Janiurek, Mette;
Lauritzen, Martin

Publication type:

Article

Correction to: Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.

Published in:

2022

By:

Kurosawa, Toshiki;
Sako, Daiki;
Tega, Yuma;
Debori, Yasuyuki;
Tomihara, Yumi;
Aoyama, Kazunobu;
Kubo, Yoshiyuki;
Amano, Nobuyuki;
Deguchi, Yoshiharu

Publication type:

Correction Notice

Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1469, doi. 10.1007/s11095-022-03251-9

By:

Sun, Austin;
Wang, Joanne

Publication type:

Article

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1535, doi. 10.1007/s11095-022-03249-3

By:

Kurosawa, Toshiki;
Sako, Daiki;
Tega, Yuma;
Debori, Yasuyuki;
Tomihara, Yumi;
Aoyama, Kazunobu;
Kubo, Yoshiyuki;
Amano, Nobuyuki;
Deguchi, Yoshiharu

Publication type:

Article

Unbound Brain-to-Plasma Partition Coefficient, K<sub>p,uu,brain</sub>—a Game Changing Parameter for CNS Drug Discovery and Development.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1321, doi. 10.1007/s11095-022-03246-6

By:

Loryan, Irena;
Reichel, Andreas;
Feng, Bo;
Bundgaard, Christoffer;
Shaffer, Christopher;
Kalvass, Cory;
Bednarczyk, Dallas;
Morrison, Denise;
Lesuisse, Dominique;
Hoppe, Edmund;
Terstappen, Georg C.;
Fischer, Holger;
Di, Li;
Colclough, Nicola;
Summerfield, Scott;
Buckley, Stephen T.;
Maurer, Tristan S.;
Fridén, Markus

Publication type:

Article

Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1415, doi. 10.1007/s11095-022-03241-x

By:

Puris, Elena;
Fricker, Gert;
Gynther, Mikko

Publication type:

Article

Correction: In Vitro—In Vivo Extrapolation of Hepatic Clearance in Preclinical Species.

Published in:

2022

By:

Tess, David A.;
Ryu, Sangwoo;
Di, Li

Publication type:

Correction Notice

To Measure is to Know: A Perspective on the Work of Dr. Margareta Hammarlund-Udenaes.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1297, doi. 10.1007/s11095-022-03225-x

By:

Griffith, Jessica I.;
Elmquist, William F.

Publication type:

Article

Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1549, doi. 10.1007/s11095-022-03223-z

By:

Kadoguchi, Moeno;
Arakawa, Hiroshi;
Honda, Ryokichi;
Hotta, Kazuki;
Shirasaka, Yoshiyuki;
Deguchi, Yoshiharu;
Tamai, Ikumi

Publication type:

Article

In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1587, doi. 10.1007/s11095-022-03218-w

By:

Nozohouri, Saeideh;
Esfahani, Shiva Hadi;
Noorani, Behnam;
Patel, Dhaval;
Villalba, Heidi;
Ghanwatkar, Yashwardhan;
Rahman, Md. Shafikur;
Zhang, Yong;
Bickel, Ulrich;
Trippier, Paul C.;
Karamyan, Vardan T.;
Abbruscato, Thomas J.

Publication type:

Article

In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1615, doi. 10.1007/s11095-022-03205-1

By:

Tess, David A.;
Ryu, Sangwoo;
Di, Li

Publication type:

Article

Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1633, doi. 10.1007/s11095-022-03197-y

By:

Öbrink-Hansen, Kristina;
Pham, Anh Duc;
Bue, Mats;
Hanberg, Pelle;
Bendtsen, Mathias;
Slater, Josefine;
Friberg, Lena E.;
Thorsted, Anders;
Stilling, Maiken

Publication type:

Article

Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1363, doi. 10.1007/s11095-022-03193-2

By:

Huttunen, Kristiina M.;
Terasaki, Tetsuya;
Urtti, Arto;
Montaser, Ahmed B.;
Uchida, Yasuo

Publication type:

Article

In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1575, doi. 10.1007/s11095-022-03189-y

By:

Ito, Ryo;
Morio, Hanae;
Baba, Tomoyo;
Sakaguchi, Yasuyuki;
Wakayama, Naomi;
Isogai, Ryuto;
Yamaura, Yoshiyuki;
Komori, Takafumi;
Furihata, Tomomi

Publication type:

Article

Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1523, doi. 10.1007/s11095-022-03186-1

By:

Ye, Zhou;
Gastfriend, Benjamin D.;
Umlauf, Benjamin J.;
Lynn, David M.;
Shusta, Eric V.

Publication type:

Article

High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1599, doi. 10.1007/s11095-022-03171-8

By:

Chen, Eugene C.;
Matsson, Pär;
Azimi, Mina;
Zhou, Xujia;
Handin, Niklas;
Yee, Sook Wah;
Artursson, Per;
Giacomini, Kathleen M.

Publication type:

Article

Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1645, doi. 10.1007/s11095-022-03165-6

By:

Fujita, Arimi;
Noguchi, Saki;
Hamada, Rika;
Inoue, Satoko;
Shimada, Tsutomu;
Katakura, Satomi;
Maruyama, Tetsuo;
Sai, Yoshimichi;
Nishimura, Tomohiro;
Tomi, Masatoshi

Publication type:

Article

The Extension of the LeiCNS-PK3.0 Model in Combination with the "Handshake" Approach to Understand Brain Tumor Pathophysiology.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1343, doi. 10.1007/s11095-021-03154-1

By:

Hirasawa, Makoto;
Saleh, Mohammed A. A.;
de Lange, Elizabeth C. M.

Publication type:

Article

Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood–Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1561, doi. 10.1007/s11095-021-03131-8

By:

Nagano, Hinako;
Ito, Shingo;
Masuda, Takeshi;
Ohtsuki, Sumio

Publication type:

Article